RAAS

シグナル伝達経路

研究分野

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S2199 Aliskiren Hemifumarate 100 mg/mL 100 mg/mL 100 mg/mL
S1657 Enalaprilat Dihydrate <1 mg/mL 70 mg/mL '<1 mg/mL
S1506 Perindopril Erbumine 88 mg/mL <1 mg/mL '88 mg/mL
S1793 Ramipril <1 mg/mL 83 mg/mL '83 mg/mL
S2488 VTP-27999 TFA 100 mg/mL 100 mg/mL 100 mg/mL
S1941 Enalapril Maleate <1 mg/mL 99 mg/mL ''4 mg/mL
S2051 Captopril 2 mg/mL 43 mg/mL '43 mg/mL
S2076 Lisinopril dihydrate 20 mg/mL <1 mg/mL ''''<1 mg/mL
S2079 Moexipril HCl <1 mg/mL 20 mg/mL ''<1 mg/mL
S2581 Quinapril HCl 95 mg/mL 18 mg/mL '95 mg/mL
S2099 Temocapril HCl <1 mg/mL 103 mg/mL '103 mg/mL
S2100 Temocapril <1 mg/mL 95 mg/mL ''95 mg/mL
S2109 Imidapril HCl 54 mg/mL 88 mg/mL '29 mg/mL
S3981 Sinapinic Acid <1 mg/mL 44 mg/mL 44 mg/mL
S7382 Phosphoramidon Disodium Salt 100 mg/mL 100 mg/mL <1 mg/mL
S5767 Aliskiren 6 mg/mL 100 mg/mL 100 mg/mL
S5728 Delapril Hydrochloride <1 mg/mL 98 mg/mL '25 mg/mL
S5712 Zofenopril calcium <1 mg/mL 5.33 mg/mL <1 mg/mL
S5938 Benazepril <1 mg/mL 85 mg/mL 85 mg/mL
S7678 Sacubitril/valsartan (LCZ696) 100 mg/mL 30 mg/mL '9 mg/mL
S6468 Trandolapril <1 mg/mL 86 mg/mL '43 mg/mL
S2095 Fosinopril Sodium 117 mg/mL <1 mg/mL ''4 mg/mL
S1284 Benazepril HCl 19 mg/mL 92 mg/mL '92 mg/mL

亜型選択性的な製品

RAAS製品

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S2199

Aliskiren Hemifumarate

Aliskiren hemifumarate is a direct renin inhibitor with IC50 of 1.5 nM.

S1657

Enalaprilat Dihydrate

Enalaprilat (MK-422) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM.

S1506

Perindopril Erbumine

Perindopril Erbumine (S9490-3) is a potent ACE inhibitor with IC50 of 1.05 nM.

S1793

Ramipril

Ramipril is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM.

S2488

VTP-27999 TFA

VTP-27999 TFA is an orally efficacious, selecitive alkyl amine renin inhibitor with IC50 of 0.47 nM for 0.3 nM of purified recombinant human renin.

S1941

Enalapril Maleate

Enalapril (MK-421) Maleate is an angiotensin-converting enzyme (ACE) inhibitor, used in the treatment of hypertension, diabetic nephropathy, and chronic heart failure.

S2051

Captopril

Captopril is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM.

S2076

Lisinopril dihydrate

Lisinopril dihydrate is an angiotensin-converting enzyme (ACE) inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications of diabetes.

S2079

Moexipril HCl

Moexipril HCl is a potent orally active nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, used for the treatment of hypertension and congestive heart failure.

S2581

Quinapril HCl

Quinapril HCl (CI-906, PD-109452-2) is the hydrochloride salt of quinapril that is an angiotensin-converting enzyme inhibitor with a Ki of 20 μM.

S2099

Temocapril HCl

Temocapril HCl is the hydrochloride of Temocapril, which is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.

S2100

Temocapril

Temocapril (CS-622) is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.

S2109

Imidapril HCl

Imidapril HCl is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.

S3981

Sinapinic Acid

Sinapinic acid (Sinapic acid), or sinapic acid is a small naturally occurring hydroxycinnamic acid which belongs to phenylpropanoid family and commonly used as matrix in MALDI mass spectrometry.

S7382

Phosphoramidon Disodium Salt

Phosphoramidon Disodium Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool. Phosphoramidon inhibited ECE, NEP, and ACE activities with IC50 values of 3.5 μM, 0.034 μM, and 78 μM, respectively.

S5767

Aliskiren

Aliskiren is a renin inhibitor with antihypertensive activity.

S5728

Delapril Hydrochloride

Delapril Hydrochloride is the hydrochloride salt form of delapril, which is a lipophilic, non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.

S5712

Zofenopril calcium

Zofenopril calcium is an angiotensin-converting enzyme (ACE) inhibitor that protects the heart and helps reduce high blood pressure.

S5938

Benazepril

Benazepril is used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure.

S7678

Sacubitril/valsartan (LCZ696)

Sacubitril/valsartan (LCZ696, Sacubitril, Valsartan), consisting of valsartan and sacubitril in 1:1 molar ratio, is an orally bioavailable, dual-acting angiotensin receptor-neprilysin inhibitor (ARNi) for hypertension and heart failure. Phase 3.

S6468

Trandolapril

Trandolapril is a newly developed angiotensin-converting enzyme (ACE) inhibitor that is rapidly hydrolyzed mainly in the liver to its biologically active metabolite trandolaprilat.

S2095

Fosinopril Sodium

Fosinopril Sodium (SQ28555) is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure.

S1284

Benazepril HCl

Benazepril HCl (CGS 14824A) is a novel angiotensin I converting enzyme inhibitor, used primarily in treatment of hypertension.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S2199

Aliskiren Hemifumarate

Aliskiren hemifumarate is a direct renin inhibitor with IC50 of 1.5 nM.

S1657

Enalaprilat Dihydrate

Enalaprilat (MK-422) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM.

S1506

Perindopril Erbumine

Perindopril Erbumine (S9490-3) is a potent ACE inhibitor with IC50 of 1.05 nM.

S1793

Ramipril

Ramipril is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM.

S2488

VTP-27999 TFA

VTP-27999 TFA is an orally efficacious, selecitive alkyl amine renin inhibitor with IC50 of 0.47 nM for 0.3 nM of purified recombinant human renin.

S1941

Enalapril Maleate

Enalapril (MK-421) Maleate is an angiotensin-converting enzyme (ACE) inhibitor, used in the treatment of hypertension, diabetic nephropathy, and chronic heart failure.

S2051

Captopril

Captopril is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM.

S2076

Lisinopril dihydrate

Lisinopril dihydrate is an angiotensin-converting enzyme (ACE) inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications of diabetes.

S2079

Moexipril HCl

Moexipril HCl is a potent orally active nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, used for the treatment of hypertension and congestive heart failure.

S2581

Quinapril HCl

Quinapril HCl (CI-906, PD-109452-2) is the hydrochloride salt of quinapril that is an angiotensin-converting enzyme inhibitor with a Ki of 20 μM.

S2099

Temocapril HCl

Temocapril HCl is the hydrochloride of Temocapril, which is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.

S2100

Temocapril

Temocapril (CS-622) is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.

S2109

Imidapril HCl

Imidapril HCl is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.

S3981

Sinapinic Acid

Sinapinic acid (Sinapic acid), or sinapic acid is a small naturally occurring hydroxycinnamic acid which belongs to phenylpropanoid family and commonly used as matrix in MALDI mass spectrometry.

S7382

Phosphoramidon Disodium Salt

Phosphoramidon Disodium Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool. Phosphoramidon inhibited ECE, NEP, and ACE activities with IC50 values of 3.5 μM, 0.034 μM, and 78 μM, respectively.

S5767

Aliskiren

Aliskiren is a renin inhibitor with antihypertensive activity.

S5728

Delapril Hydrochloride

Delapril Hydrochloride is the hydrochloride salt form of delapril, which is a lipophilic, non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.

S5712

Zofenopril calcium

Zofenopril calcium is an angiotensin-converting enzyme (ACE) inhibitor that protects the heart and helps reduce high blood pressure.

S5938

Benazepril

Benazepril is used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure.

S7678

Sacubitril/valsartan (LCZ696)

Sacubitril/valsartan (LCZ696, Sacubitril, Valsartan), consisting of valsartan and sacubitril in 1:1 molar ratio, is an orally bioavailable, dual-acting angiotensin receptor-neprilysin inhibitor (ARNi) for hypertension and heart failure. Phase 3.

S6468

Trandolapril

Trandolapril is a newly developed angiotensin-converting enzyme (ACE) inhibitor that is rapidly hydrolyzed mainly in the liver to its biologically active metabolite trandolaprilat.

S2095

Fosinopril Sodium

Fosinopril Sodium (SQ28555) is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S1284

Benazepril HCl

Benazepril HCl (CGS 14824A) is a novel angiotensin I converting enzyme inhibitor, used primarily in treatment of hypertension.

2015, 12(9):3399-407