RAAS
阻害剤の選択性比較
カタログ番号 | 製品カタログ | 溶解度(25°C) | ||
---|---|---|---|---|
水 | DMSO | アルコール | ||
S2199 | Aliskiren Hemifumarate | 100 mg/mL | 100 mg/mL | 100 mg/mL |
S1657 | Enalaprilat Dihydrate | <1 mg/mL | 70 mg/mL | <1 mg/mL |
S1506 | Perindopril Erbumine | 88 mg/mL | <1 mg/mL | 88 mg/mL |
S1793 | Ramipril | <1 mg/mL | 83 mg/mL | 83 mg/mL |
S2488 | VTP-27999 TFA | 100 mg/mL | 100 mg/mL | '100 mg/mL |
S1941 | Enalapril Maleate | <1 mg/mL | 99 mg/mL | 4 mg/mL |
S2051 | Captopril | 2 mg/mL | 43 mg/mL | 43 mg/mL |
S2076 | Lisinopril dihydrate | 20 mg/mL | <1 mg/mL | <1 mg/mL |
S2079 | Moexipril HCl | <1 mg/mL | 20 mg/mL | <1 mg/mL |
S2581 | Quinapril HCl | 95 mg/mL | 18 mg/mL | 95 mg/mL |
S2099 | Temocapril HCl | <1 mg/mL | 103 mg/mL | 103 mg/mL |
S2100 | Temocapril | <1 mg/mL | 95 mg/mL | 95 mg/mL |
S2109 | Imidapril HCl | 54 mg/mL | 88 mg/mL | 29 mg/mL |
S7382 | Phosphoramidon Disodium Salt | 100 mg/mL | 100 mg/mL | <1 mg/mL |
S5767 | Aliskiren | 6 mg/mL | 100 mg/mL | 100 mg/mL |
S5728 | Delapril Hydrochloride | <1 mg/mL | 98 mg/mL | 25 mg/mL |
S5712 | Zofenopril calcium | <1 mg/mL | 5.33 mg/mL | '<1 mg/mL |
S5938 | Benazepril | <1 mg/mL | 85 mg/mL | 85 mg/mL |
S6468 | Trandolapril | <1 mg/mL | 86 mg/mL | 43 mg/mL |
S2095 | Fosinopril Sodium | 117 mg/mL | <1 mg/mL | 4 mg/mL |
S1284 | Benazepril HCl | 19 mg/mL | 92 mg/mL | 92 mg/mL |
RAAS製品
製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
---|---|---|---|
S2199 |
Aliskiren HemifumarateAliskiren hemifumarate is a direct renin inhibitor with IC50 of 1.5 nM. |
||
S1657 |
Enalaprilat DihydrateEnalaprilat (MK-422) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM. |
||
S1506 |
Perindopril ErbuminePerindopril Erbumine (S9490-3) is a pro-drug and metabolized in vivo by hydrolysis of the ester group to form Perindoprilat, the biologically active metabolite, a potent ACE inhibitor with IC50 of 1.05 nM. Perindopril Erbumine is used for in vivo studies and Perindoprilat is recommened for in vitro research. |
||
S1793 |
RamiprilRamipril is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM. |
||
S2488新 |
VTP-27999 TFAVTP-27999 TFA (VTP-27999 Trifluoroacetate, VTP-27999 2,2,2-trifluoroacetate) is an orally efficacious, selecitive alkyl amine renin inhibitor with IC50 of 0.47 nM for 0.3 nM of purified recombinant human renin. |
||
S1941 |
Enalapril MaleateEnalapril (MK-421) Maleate is an angiotensin-converting enzyme (ACE) inhibitor, used in the treatment of hypertension, diabetic nephropathy, and chronic heart failure. |
||
S2051 |
CaptoprilCaptopril (SQ 14225) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM. |
||
S2076 |
Lisinopril dihydrateLisinopril dihydrate is an angiotensin-converting enzyme (ACE) inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications of diabetes. |
||
S2079 |
Moexipril HClMoexipril HCl (RS-10085) is a potent orally active nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, used for the treatment of hypertension and congestive heart failure. |
||
S2581 |
Quinapril HClQuinapril HCl (CI-906, PD-109452-2) is the hydrochloride salt of quinapril that is an angiotensin-converting enzyme inhibitor with a Ki of 20 μM. |
||
S2099 |
Temocapril HClTemocapril HCl (CS-622) is the hydrochloride of Temocapril, which is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension. |
||
S2100 |
TemocaprilTemocapril (CS-622) is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension. |
||
S2109 |
Imidapril HClImidapril HCl is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension. |
||
S7382 |
Phosphoramidon Disodium SaltPhosphoramidon Disodium Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool. Phosphoramidon inhibited ECE, NEP, and ACE activities with IC50 values of 3.5 μM, 0.034 μM, and 78 μM, respectively. |
||
S5767 |
AliskirenAliskiren is a renin inhibitor with antihypertensive activity. |
||
S5728 |
Delapril HydrochlorideDelapril Hydrochloride (Alindapril) is the hydrochloride salt form of delapril, which is a lipophilic, non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. |
||
S5712 |
Zofenopril calciumZofenopril calcium (SQ-26991) is an angiotensin-converting enzyme (ACE) inhibitor that protects the heart and helps reduce high blood pressure. |
||
S5938 |
BenazeprilBenazepril is used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure. |
||
S6468 |
TrandolaprilTrandolapril is a newly developed angiotensin-converting enzyme (ACE) inhibitor that is rapidly hydrolyzed mainly in the liver to its biologically active metabolite trandolaprilat. |
||
S2095 |
Fosinopril SodiumFosinopril Sodium (SQ28555) is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure. |
||
S1284 |
Benazepril HClBenazepril HCl (CGS 14824A) is a novel angiotensin I converting enzyme inhibitor, used primarily in treatment of hypertension. |
製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
---|---|---|---|
S2199 |
Aliskiren HemifumarateAliskiren hemifumarate is a direct renin inhibitor with IC50 of 1.5 nM. |
||
S1657 |
Enalaprilat DihydrateEnalaprilat (MK-422) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM. |
||
S1506 |
Perindopril ErbuminePerindopril Erbumine (S9490-3) is a pro-drug and metabolized in vivo by hydrolysis of the ester group to form Perindoprilat, the biologically active metabolite, a potent ACE inhibitor with IC50 of 1.05 nM. Perindopril Erbumine is used for in vivo studies and Perindoprilat is recommened for in vitro research. |
||
S1793 |
RamiprilRamipril is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM. |
||
S2488新 |
VTP-27999 TFAVTP-27999 TFA (VTP-27999 Trifluoroacetate, VTP-27999 2,2,2-trifluoroacetate) is an orally efficacious, selecitive alkyl amine renin inhibitor with IC50 of 0.47 nM for 0.3 nM of purified recombinant human renin. |
||
S1941 |
Enalapril MaleateEnalapril (MK-421) Maleate is an angiotensin-converting enzyme (ACE) inhibitor, used in the treatment of hypertension, diabetic nephropathy, and chronic heart failure. |
||
S2051 |
CaptoprilCaptopril (SQ 14225) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM. |
||
S2076 |
Lisinopril dihydrateLisinopril dihydrate is an angiotensin-converting enzyme (ACE) inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications of diabetes. |
||
S2079 |
Moexipril HClMoexipril HCl (RS-10085) is a potent orally active nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, used for the treatment of hypertension and congestive heart failure. |
||
S2581 |
Quinapril HClQuinapril HCl (CI-906, PD-109452-2) is the hydrochloride salt of quinapril that is an angiotensin-converting enzyme inhibitor with a Ki of 20 μM. |
||
S2099 |
Temocapril HClTemocapril HCl (CS-622) is the hydrochloride of Temocapril, which is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension. |
||
S2100 |
TemocaprilTemocapril (CS-622) is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension. |
||
S2109 |
Imidapril HClImidapril HCl is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension. |
||
S7382 |
Phosphoramidon Disodium SaltPhosphoramidon Disodium Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool. Phosphoramidon inhibited ECE, NEP, and ACE activities with IC50 values of 3.5 μM, 0.034 μM, and 78 μM, respectively. |
||
S5767 |
AliskirenAliskiren is a renin inhibitor with antihypertensive activity. |
||
S5728 |
Delapril HydrochlorideDelapril Hydrochloride (Alindapril) is the hydrochloride salt form of delapril, which is a lipophilic, non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. |
||
S5712 |
Zofenopril calciumZofenopril calcium (SQ-26991) is an angiotensin-converting enzyme (ACE) inhibitor that protects the heart and helps reduce high blood pressure. |
||
S5938 |
BenazeprilBenazepril is used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure. |
||
S6468 |
TrandolaprilTrandolapril is a newly developed angiotensin-converting enzyme (ACE) inhibitor that is rapidly hydrolyzed mainly in the liver to its biologically active metabolite trandolaprilat. |
||
S2095 |
Fosinopril SodiumFosinopril Sodium (SQ28555) is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure. |
製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
---|---|---|---|
S1284 |
Benazepril HClBenazepril HCl (CGS 14824A) is a novel angiotensin I converting enzyme inhibitor, used primarily in treatment of hypertension. |
2015, 12(9):3399-407 |