RAD51

RAD51製品

All (4)
RAD51阻害剤 (3)
RAD51活性剤(1)
新製品

製品コード	製品名称	製品説明	文献中Selleckの製品使用例	お客様のフィードバック
S2871	T0070907	T0070907 is a potent inhibitor of PPARγ (peroxisome proliferator activator receptor γ ) that induces G2/M arrest and enhances the effect of radiation in human cervical cancer cells through mitotic catastrophe. It also acts as an antagonist of PPARγ that suppresses breast cancer cell proliferation and motility via both PPARgamma-dependent and -independent mechanisms.	Nat Commun, 2024, 15(1):1429 Cell Discov, 2023, 9(1):54 Cell Discov, 2023, 9(1):54
S1244	Amuvatinib (MP-470)	Amuvatinib (MP-470, HPK 56) is a potent and multi-targeted inhibitor of c-Kit, PDGFRα and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively. Amuvatinib suppresses c-MET and c-RET. Amuvatinib is also active as a DNA repair protein Rad51 inhibitor with antineoplastic activity. Phase 2.	Microbiol Spectr, 2023, e0510522. J Pers Med, 2022, 12(2)258 Hum Cell, 2022, 10.1007/s13577-022-00671-y
S8077	RI-1	RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor with IC50 ranging from 5 to 30 μM.	Int J Mol Sci, 2023, 24(3)2498 Biomed Rep, 2023, 18(4):28 Clin Exp Pharmacol Physiol, 2022, 10.1111/1440-1681.13646
S8234	RS-1	RS-1 is a RAD51-stimulatory compound, which increases the DNA binding activity of RAD51. It is an HDR(homology-directed repair) enhancer.	Int J Biol Sci, 2021, 17(4):1026-1040 Chembiochem, 2021, 22(20):2957-2965
S2871	T0070907	T0070907 is a potent inhibitor of PPARγ (peroxisome proliferator activator receptor γ ) that induces G2/M arrest and enhances the effect of radiation in human cervical cancer cells through mitotic catastrophe. It also acts as an antagonist of PPARγ that suppresses breast cancer cell proliferation and motility via both PPARgamma-dependent and -independent mechanisms.	Nat Commun, 2024, 15(1):1429 Cell Discov, 2023, 9(1):54 Cell Discov, 2023, 9(1):54
S1244	Amuvatinib (MP-470)	Amuvatinib (MP-470, HPK 56) is a potent and multi-targeted inhibitor of c-Kit, PDGFRα and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively. Amuvatinib suppresses c-MET and c-RET. Amuvatinib is also active as a DNA repair protein Rad51 inhibitor with antineoplastic activity. Phase 2.	Microbiol Spectr, 2023, e0510522. J Pers Med, 2022, 12(2)258 Hum Cell, 2022, 10.1007/s13577-022-00671-y
S8077	RI-1	RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor with IC50 ranging from 5 to 30 μM.	Int J Mol Sci, 2023, 24(3)2498 Biomed Rep, 2023, 18(4):28 Clin Exp Pharmacol Physiol, 2022, 10.1111/1440-1681.13646
S8234	RS-1	RS-1 is a RAD51-stimulatory compound, which increases the DNA binding activity of RAD51. It is an HDR(homology-directed repair) enhancer.	Int J Biol Sci, 2021, 17(4):1026-1040 Chembiochem, 2021, 22(20):2957-2965

RAD51阻害剤の選択性比較

Tags: RAD51 inhibitor | RAD51 activator | RAD51 modulator