SUMO

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S8829 TAK-981 <1 mg/mL 100 mg/mL <1 mg/mL
S8696 2-D08 <1 mg/mL 54 mg/mL <1 mg/mL
S9432 Ginkgolic Acid -1 mg/mL 69 mg/mL -1 mg/mL
S9445 Ginkgolic Acid (C13:0) -1 mg/mL 64 mg/mL -1 mg/mL
S9159 momordin-Ic -1 mg/mL 100 mg/mL -1 mg/mL

SUMO製品

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S8829

TAK-981

TAK-981 is a novel, selective inhibitor of the SUMOylation enzymatic cascade with potential immune-activating and antineoplastic activities.

S8696

2-D08

2-D08 (2',3',4'-trihydroxy flavone) is a cell permeable, mechanistically unique inhibitor of protein sumoylation. It is also inhibits Axl, IRAK4, ROS1, MLK4, GSK3β, RET, KDR and PI3Kα with IC50 values of 0.49, 3.9, 5.3, 9.8, 11, 11, 17 and 35 nM respectively in biochemical assays.

S9432

Ginkgolic Acid

Ginkgolic acid, toxic phenolic compounds present in the fruits and leaves of Ginkgo biloba L., is a potent sumoylation inhibitor also reported to inhibit histone acetylation transferase (HAT).

S9445

Ginkgolic Acid (C13:0)

Ginkgolic Acid (C13:0) is a natural anticariogenic agent in Ginkgo biloba L. that exhibits antimicrobial activity against S. mutans and suppresses the specific virulence factors associated with its cariogenicity. Ginkgolic acid is a potent sumoylation inhibitor and reported to inhibit histone acetylation transferase (HAT).

S9159

momordin-Ic

Momordin Ic, a natural triterpenoid saponin, is a novel SENP1 (SUMO-specific protease 1) inhibitor that inhibited proliferation of prostate cancer cells in vitro and in vivo.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S8829

TAK-981

TAK-981 is a novel, selective inhibitor of the SUMOylation enzymatic cascade with potential immune-activating and antineoplastic activities.

S8696

2-D08

2-D08 (2',3',4'-trihydroxy flavone) is a cell permeable, mechanistically unique inhibitor of protein sumoylation. It is also inhibits Axl, IRAK4, ROS1, MLK4, GSK3β, RET, KDR and PI3Kα with IC50 values of 0.49, 3.9, 5.3, 9.8, 11, 11, 17 and 35 nM respectively in biochemical assays.

S9432

Ginkgolic Acid

Ginkgolic acid, toxic phenolic compounds present in the fruits and leaves of Ginkgo biloba L., is a potent sumoylation inhibitor also reported to inhibit histone acetylation transferase (HAT).

S9445

Ginkgolic Acid (C13:0)

Ginkgolic Acid (C13:0) is a natural anticariogenic agent in Ginkgo biloba L. that exhibits antimicrobial activity against S. mutans and suppresses the specific virulence factors associated with its cariogenicity. Ginkgolic acid is a potent sumoylation inhibitor and reported to inhibit histone acetylation transferase (HAT).

S9159

momordin-Ic

Momordin Ic, a natural triterpenoid saponin, is a novel SENP1 (SUMO-specific protease 1) inhibitor that inhibited proliferation of prostate cancer cells in vitro and in vivo.

Tags: SUMO Inhibition | SUMO antibody | SUMO inhibitors | SUMO modulation