SUMO
阻害剤の選択性比較
| カタログ番号 | 製品カタログ | 溶解度(25°C) | ||
|---|---|---|---|---|
| 水 | DMSO | アルコール | ||
| S4922 | NSC 632839 | <1 mg/mL | 7 mg/mL | ''''<1 mg/mL |
| S8829 | Subasumstat (TAK-981) | <1 mg/mL | 100 mg/mL | ''<1 mg/mL |
| S8696 | 2-D08 | <1 mg/mL | 54 mg/mL | '<1 mg/mL |
| S9432 | Ginkgolic Acid | -1 mg/mL | 69 mg/mL | -1 mg/mL |
| S9445 | Ginkgolic Acid (C13:0) | -1 mg/mL | 64 mg/mL | -1 mg/mL |
| S9159 | momordin-Ic | -1 mg/mL | 100 mg/mL | -1 mg/mL |
SUMO製品
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| S4922 |
NSC 632839NSC 632839 is not only a DUB inhibitor, but also a deSUMOylase inhibitor, it inhibits USP2, USP7, and SENP2 with EC50 of 45 μM, 37 μM, and 9.8 μM, respectively. |
||
| S8829新 |
Subasumstat (TAK-981)Subasumstat (TAK-981) is a novel, selective inhibitor of the SUMOylation enzymatic cascade with potential immune-activating and antineoplastic activities. |
||
| S8696 |
2-D082-D08 (2',3',4'-trihydroxy flavone) is a cell permeable, mechanistically unique inhibitor of protein sumoylation. It is also inhibits Axl, IRAK4, ROS1, MLK4, GSK3β, RET (c-RET), KDR and PI3Kα with IC50 values of 0.49, 3.9, 5.3, 9.8, 11, 11, 17 and 35 nM respectively in biochemical assays. |
||
| S9432 |
Ginkgolic AcidGinkgolic acid, toxic phenolic compounds present in the fruits and leaves of Ginkgo biloba L., is a potent sumoylation inhibitor also reported to inhibit histone acetylation transferase (HAT). |
||
| S9445 |
Ginkgolic Acid (C13:0)Ginkgolic Acid (C13:0) is a natural anticariogenic agent in Ginkgo biloba L. that exhibits antimicrobial activity against S. mutans and suppresses the specific virulence factors associated with its cariogenicity. Ginkgolic acid is a potent sumoylation inhibitor and reported to inhibit histone acetylation transferase (HAT). |
||
| S9159 |
momordin-IcMomordin Ic, a natural triterpenoid saponin, is a novel SENP1 (SUMO-specific protease 1) inhibitor that inhibited proliferation of prostate cancer cells in vitro and in vivo. |
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| S4922 |
NSC 632839NSC 632839 is not only a DUB inhibitor, but also a deSUMOylase inhibitor, it inhibits USP2, USP7, and SENP2 with EC50 of 45 μM, 37 μM, and 9.8 μM, respectively. |
||
| S8829新 |
Subasumstat (TAK-981)Subasumstat (TAK-981) is a novel, selective inhibitor of the SUMOylation enzymatic cascade with potential immune-activating and antineoplastic activities. |
||
| S8696 |
2-D082-D08 (2',3',4'-trihydroxy flavone) is a cell permeable, mechanistically unique inhibitor of protein sumoylation. It is also inhibits Axl, IRAK4, ROS1, MLK4, GSK3β, RET (c-RET), KDR and PI3Kα with IC50 values of 0.49, 3.9, 5.3, 9.8, 11, 11, 17 and 35 nM respectively in biochemical assays. |
||
| S9432 |
Ginkgolic AcidGinkgolic acid, toxic phenolic compounds present in the fruits and leaves of Ginkgo biloba L., is a potent sumoylation inhibitor also reported to inhibit histone acetylation transferase (HAT). |
||
| S9445 |
Ginkgolic Acid (C13:0)Ginkgolic Acid (C13:0) is a natural anticariogenic agent in Ginkgo biloba L. that exhibits antimicrobial activity against S. mutans and suppresses the specific virulence factors associated with its cariogenicity. Ginkgolic acid is a potent sumoylation inhibitor and reported to inhibit histone acetylation transferase (HAT). |
||
| S9159 |
momordin-IcMomordin Ic, a natural triterpenoid saponin, is a novel SENP1 (SUMO-specific protease 1) inhibitor that inhibited proliferation of prostate cancer cells in vitro and in vivo. |
