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ABC Transporter
ABC Transporter製品
- All (9)
- ABC Transporter阻害剤 (7)
- ABC Transporter拮抗剤(1)
- ABC Transporterモジュレータ(1)
- 新製品
| 製品コード | 製品名称 | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|---|
| S1082 | Vismodegib (GDC-0449) | Vismodegib (GDC-0449) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM in a cell-free assay. |
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| S2492 | Novobiocin Sodium (NSC 2382) | Novobiocin Sodium (NSC 2382, Albamycin, Cathomycin) is an aminocoumarin antibiotic that targets bacterial DNA gyrase (TopoIV), used to treat susceptible gram positive bacteria. |
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| S1715 | Glipizide | Glipizide (CP-28720,K 4024) is used to treat high blood sugar levels caused by a type of diabetes mellitus called type 2 diabetes. | ||
| S1424 | Prazosin HCl | Prazosin HCl (cp-12299-1) is a competitive alpha-1 adrenoceptor antagonist, used to treat high blood pressure or benign prostatic hyperplasia. | ||
| S4166 | Chlorpropamide | Chlorpropamide inhibits Na(+),K(+)-ATPase and stimulates a high affinity cyclic AMP-phosphodiesterase of isolated liver plasma membrane. Chlorpropamide is a sulfonylurea class drug for type 2 diabetes mellitus. | ||
| S2119 | Probucol | Probucol (DH-581) is an anti-hyperlipidemic drug by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism. | ||
| S7043 | Ko143 | KO143 is a potent and relatively selective ATP-binding cassette sub-family G member 2 (ABCG2/BCRP) inhibitor. KO143 decreases the ATPase activity of ABCG2 with IC50 of 9.7 nM. | ||
| E5770 | DIDS sodium salt | DIDS sodium salt (MDL101114ZA) is a pharmacological inhibitor of voltage-dependent anion channel 1 (VDAC1), which effectively suppresses apoptosis in THP-1 macrophages. It also acts as an antagonist of ABCA1 and inhibits RAD51-mediated homologous pairing and strand exchange reactions. | ||
| E7972 | Isosilybin A | Isosilybin A is a flavonolignan isolated from silymarin that exhibits anti-prostate cancer (PCA) efficacy with an IC50 of 32 μM in DU145 cells. It induces growth inhibition, G1 arrest, and apoptosis in PCA cells by targeting the Akt-NF-κB-AR axis, highlighting its potential as a therapeutic agent in clinical prostate cancer (PCA) management. | ||
| S1082 | Vismodegib (GDC-0449) | Vismodegib (GDC-0449) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM in a cell-free assay. |
|
|
| S2492 | Novobiocin Sodium (NSC 2382) | Novobiocin Sodium (NSC 2382, Albamycin, Cathomycin) is an aminocoumarin antibiotic that targets bacterial DNA gyrase (TopoIV), used to treat susceptible gram positive bacteria. |
|
|
| S1715 | Glipizide | Glipizide (CP-28720,K 4024) is used to treat high blood sugar levels caused by a type of diabetes mellitus called type 2 diabetes. | ||
| S4166 | Chlorpropamide | Chlorpropamide inhibits Na(+),K(+)-ATPase and stimulates a high affinity cyclic AMP-phosphodiesterase of isolated liver plasma membrane. Chlorpropamide is a sulfonylurea class drug for type 2 diabetes mellitus. | ||
| S7043 | Ko143 | KO143 is a potent and relatively selective ATP-binding cassette sub-family G member 2 (ABCG2/BCRP) inhibitor. KO143 decreases the ATPase activity of ABCG2 with IC50 of 9.7 nM. | ||
| E5770 | DIDS sodium salt | DIDS sodium salt (MDL101114ZA) is a pharmacological inhibitor of voltage-dependent anion channel 1 (VDAC1), which effectively suppresses apoptosis in THP-1 macrophages. It also acts as an antagonist of ABCA1 and inhibits RAD51-mediated homologous pairing and strand exchange reactions. | ||
| E7972 | Isosilybin A | Isosilybin A is a flavonolignan isolated from silymarin that exhibits anti-prostate cancer (PCA) efficacy with an IC50 of 32 μM in DU145 cells. It induces growth inhibition, G1 arrest, and apoptosis in PCA cells by targeting the Akt-NF-κB-AR axis, highlighting its potential as a therapeutic agent in clinical prostate cancer (PCA) management. | ||
| S1424 | Prazosin HCl | Prazosin HCl (cp-12299-1) is a competitive alpha-1 adrenoceptor antagonist, used to treat high blood pressure or benign prostatic hyperplasia. | ||
| S2119 | Probucol | Probucol (DH-581) is an anti-hyperlipidemic drug by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism. |
納期 国内在庫品：受注日の翌日（15時までの受注分） ＊北海道、九州、沖縄への配送は受注日より２日以上 を要する場合あり 海外在庫品：受注後１〜２週間