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S6415 Azeliragon (TTP488) Azeliragon (TTP488, PF-04494700) is an orally bioavailable small molecule that inhibits the receptor for advanced glycation endproducts (RAGE), which is an immunoglobulin-like cell surface receptor overexpressed in brain tissues of patients with AD.
Oncogene, 2025, 44(15):1051-1062
iScience, 2025, 28(8):113063
Circ J, 2025, 10.1253/circj.CJ-24-0878
S6415 Azeliragon (TTP488) Azeliragon (TTP488, PF-04494700) is an orally bioavailable small molecule that inhibits the receptor for advanced glycation endproducts (RAGE), which is an immunoglobulin-like cell surface receptor overexpressed in brain tissues of patients with AD.
Oncogene, 2025, 44(15):1051-1062
iScience, 2025, 28(8):113063
Circ J, 2025, 10.1253/circj.CJ-24-0878
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