Apelin receptor

Apelin receptor製品

All (4)
Apelin receptor阻害剤 (1)
Apelin receptor拮抗剤(1)
Apelin receptor作動薬(1)
新製品

製品コード	製品名称	製品説明	文献中Selleckの製品使用例
S8695	ML221	ML221 is a potent apelin receptor (APJ) functional antagonist in cell-based assays that is >37-fold selective over the closely related angiotensin II type 1 (AT1) receptor. The IC50 values of ML221 are 0.70 and 1.75 μM in a cAMP assay and β-arrestin assay, respectively.	Nat Commun, 2022, 13(1):4229 Nat Commun, 2022, 13(1):4229 J Mol Cell Cardiol, 2021, S0022-2828(21)00246-7
E7448	[Pyr1]-Apelin-13	[Pyr1]-Apelin-13 is one of the endogenous agonists of the APJ receptor with high binding affinity Kd of 4.5 nM for hAPJ, predominantly found in the myocardium and plasma. It exhibits analgesic effects and improves cardiovascular function, making it a promising candidate for neuropathic pain and heart failure research.
E1928^New	Azelaprag	Azelaprag (AMG 986) is a potent agonist of apelin receptor (APJ) with an EC50 of 0.32 nM. It exhibits potential and can be used in Heart failure (HF) research.
E1928^New	Azelaprag	Azelaprag (AMG 986) is a potent agonist of apelin receptor (APJ) with an EC50 of 0.32 nM. It exhibits potential and can be used in Heart failure (HF) research.
E7448	[Pyr1]-Apelin-13	[Pyr1]-Apelin-13 is one of the endogenous agonists of the APJ receptor with high binding affinity Kd of 4.5 nM for hAPJ, predominantly found in the myocardium and plasma. It exhibits analgesic effects and improves cardiovascular function, making it a promising candidate for neuropathic pain and heart failure research.
S8695	ML221	ML221 is a potent apelin receptor (APJ) functional antagonist in cell-based assays that is >37-fold selective over the closely related angiotensin II type 1 (AT1) receptor. The IC50 values of ML221 are 0.70 and 1.75 μM in a cAMP assay and β-arrestin assay, respectively.	Nat Commun, 2022, 13(1):4229 Nat Commun, 2022, 13(1):4229 J Mol Cell Cardiol, 2021, S0022-2828(21)00246-7
E1928^New	Azelaprag	Azelaprag (AMG 986) is a potent agonist of apelin receptor (APJ) with an EC50 of 0.32 nM. It exhibits potential and can be used in Heart failure (HF) research.
E1928^New	Azelaprag	Azelaprag (AMG 986) is a potent agonist of apelin receptor (APJ) with an EC50 of 0.32 nM. It exhibits potential and can be used in Heart failure (HF) research.
E1928^New	Azelaprag	Azelaprag (AMG 986) is a potent agonist of apelin receptor (APJ) with an EC50 of 0.32 nM. It exhibits potential and can be used in Heart failure (HF) research.