CD markers

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S2632 BMS-378806 <1 mg/mL 81 mg/mL 3 mg/mL
S3301 Cynarin -1 mg/mL 100 mg/mL -1 mg/mL
S0141 NQ301 <1 mg/mL 30 mg/mL <1 mg/mL
S7487 YYA-021 <1 mg/mL 0.01 mg/mL <1 mg/mL
S8960 CD38 inhibitor 1 (compound 78c) <1 mg/mL 83 mg/mL <1 mg/mL
S0215 MDK 24720 (CTLA-4 inhibitor) -1 mg/mL 85 mg/mL -1 mg/mL
S6727 AX-024 HCl 4 mg/mL 75 mg/mL 18 mg/mL

CD markers製品

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S2632

BMS-378806

BMS-378806 (BMS 806) selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus.

S3301

Cynarin

Cynarin (Cynarine) is an artichoke phytochemical that possesses a variety of pharmacological features including free-radical scavenging, antioxidant, antihistamic and antiviral activities. Cynarin blocks the interaction between the CD28 of T-cell receptor and CD80 of antigen presenting cells. Cynarin triggers Nrf2 nuclear translocation, restores the balance of glutathione (GSH) and reactive oxygen species (ROS), and inhibits mitochondrial depolarization.

S0141

NQ301

NQ301 (compound 211), an antiplatelet and antithrombotic agent, is a selective CD45 inhibitor with IC50 of 200 nM. NQ301 inhibits thromboxane A2 receptor (TXA2) and synthase activity in rabbit platelets.

S7487

YYA-021

YYA-021 is a CD4-mimic HIV entry inhibitor, competitively inhibiting the interaction between gp120 and CD4.

S8960

CD38 inhibitor 1 (compound 78c)

CD38 inhibitor 1 (compound 78c, CD38-IN-78c, MDK-7553) is a potent inhibitor of CD38 with IC50 of 7.3 nM and 1.9 nM for human CD38 and mouse CD38, respetively.

S0215

MDK 24720 (CTLA-4 inhibitor)

MDK 24720 (CTLA-4 inhibitor, copmound 6b) is an inhibitor of Cytotoxic T-Lymphocyte-Associated protein 4 (CTLA-4, CD152) with IC50 of 50 nM for B7.1–CD28 inhibition.

S6727

AX-024 HCl

AX-024 HCl blocks the interaction of the CD3ε PRS with SH3.1(Nck). AX-024 HCl also inhibits IL-6, TNF-α, IFN-γ, IL-10 and IL-17A.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S2632

BMS-378806

BMS-378806 (BMS 806) selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus.

S3301

Cynarin

Cynarin (Cynarine) is an artichoke phytochemical that possesses a variety of pharmacological features including free-radical scavenging, antioxidant, antihistamic and antiviral activities. Cynarin blocks the interaction between the CD28 of T-cell receptor and CD80 of antigen presenting cells. Cynarin triggers Nrf2 nuclear translocation, restores the balance of glutathione (GSH) and reactive oxygen species (ROS), and inhibits mitochondrial depolarization.

S0141

NQ301

NQ301 (compound 211), an antiplatelet and antithrombotic agent, is a selective CD45 inhibitor with IC50 of 200 nM. NQ301 inhibits thromboxane A2 receptor (TXA2) and synthase activity in rabbit platelets.

S7487

YYA-021

YYA-021 is a CD4-mimic HIV entry inhibitor, competitively inhibiting the interaction between gp120 and CD4.

S8960

CD38 inhibitor 1 (compound 78c)

CD38 inhibitor 1 (compound 78c, CD38-IN-78c, MDK-7553) is a potent inhibitor of CD38 with IC50 of 7.3 nM and 1.9 nM for human CD38 and mouse CD38, respetively.

S0215

MDK 24720 (CTLA-4 inhibitor)

MDK 24720 (CTLA-4 inhibitor, copmound 6b) is an inhibitor of Cytotoxic T-Lymphocyte-Associated protein 4 (CTLA-4, CD152) with IC50 of 50 nM for B7.1–CD28 inhibition.

S6727

AX-024 HCl

AX-024 HCl blocks the interaction of the CD3ε PRS with SH3.1(Nck). AX-024 HCl also inhibits IL-6, TNF-α, IFN-γ, IL-10 and IL-17A.