cGAS
阻害剤の選択性比較
| カタログ番号 | 製品カタログ | 溶解度(25°C) | ||
|---|---|---|---|---|
| 水 | DMSO | アルコール | ||
| S6841 | RU.521 | ˂1 mg/mL | 83 mg/mL | '2 mg/mL |
| S9615 | PF-06928215 | ' mg/mL | ||
| S0775 | IRAK4-IN-4 | <1 mg/mL | 68 mg/mL | '''68 mg/mL |
| S8944 | G150 | <1 mg/mL | 78 mg/mL | 2 mg/mL |
cGAS製品
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| S6841 |
RU.521RU.521 (RU320521) is an active, potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS) that inhibits the cGAS-mediated signaling with IC50 of 700 nM. RU.521 binds to the cGAS/dsDNA complex with Kd of 36.2 nM. |
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| S9615新 |
PF-06928215PF-06928215 is a high affinity inhibitor of cyclic GMP-AMP synthase (cGAS) with an IC50 of 4.9 μM. |
||
| S0775 |
IRAK4-IN-4IRAK4-IN-4 (compound 15) is an inhibitor of interleukin-1 receptor–associated kinase 4 (IRAK4) and cyclic GMP-AMP synthase (cGAS) with IC50 of 2.8 nM and 2.1 nM, respectively. |
||
| S8944 |
G150G150 is a potent and highly selective human cyclic GMP-AMP synthase (cGAS) inhibitor with IC50 of 10.2 nM. |
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| S6841 |
RU.521RU.521 (RU320521) is an active, potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS) that inhibits the cGAS-mediated signaling with IC50 of 700 nM. RU.521 binds to the cGAS/dsDNA complex with Kd of 36.2 nM. |
||
| S9615新 |
PF-06928215PF-06928215 is a high affinity inhibitor of cyclic GMP-AMP synthase (cGAS) with an IC50 of 4.9 μM. |
||
| S0775 |
IRAK4-IN-4IRAK4-IN-4 (compound 15) is an inhibitor of interleukin-1 receptor–associated kinase 4 (IRAK4) and cyclic GMP-AMP synthase (cGAS) with IC50 of 2.8 nM and 2.1 nM, respectively. |
||
| S8944 |
G150G150 is a potent and highly selective human cyclic GMP-AMP synthase (cGAS) inhibitor with IC50 of 10.2 nM. |
