cGAS

cGAS製品

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  • cGAS阻害剤 (5)
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製品コード 製品名称 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S6841 RU.521 RU.521 (RU320521) is an active, potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS) that inhibits the cGAS-mediated signaling with IC50 of 700 nM. RU.521 binds to the cGAS/dsDNA complex with Kd of 36.2 nM.
Cancer Lett, 2024, 586:216695
Phytomedicine, 2023, 120:155020
iScience, 2023, 26(10):107792
S8944 G150 G150 is a potent and highly selective human cyclic GMP-AMP synthase (cGAS) inhibitor with IC50 of 10.2 nM.
J Leukoc Biol, 2022, 10.1002/JLB.4MA0422-616R
S9615 PF-06928215 PF-06928215 is a high affinity inhibitor of cyclic GMP-AMP synthase (cGAS) with an IC50 of 4.9 μM.
S0775 IRAK4-IN-4 IRAK4-IN-4 (compound 15) is an inhibitor of interleukin-1 receptor–associated kinase 4 (IRAK4) and cyclic GMP-AMP synthase (cGAS) with IC50 of 2.8 nM and 2.1 nM, respectively.
S9945 G140 G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS), with IC50s of 14.0 nM and 442 nM for h-cGAS and m-cGAS, respectively.
S6841 RU.521 RU.521 (RU320521) is an active, potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS) that inhibits the cGAS-mediated signaling with IC50 of 700 nM. RU.521 binds to the cGAS/dsDNA complex with Kd of 36.2 nM.
Cancer Lett, 2024, 586:216695
Phytomedicine, 2023, 120:155020
iScience, 2023, 26(10):107792
S8944 G150 G150 is a potent and highly selective human cyclic GMP-AMP synthase (cGAS) inhibitor with IC50 of 10.2 nM.
J Leukoc Biol, 2022, 10.1002/JLB.4MA0422-616R
S9615 PF-06928215 PF-06928215 is a high affinity inhibitor of cyclic GMP-AMP synthase (cGAS) with an IC50 of 4.9 μM.
S0775 IRAK4-IN-4 IRAK4-IN-4 (compound 15) is an inhibitor of interleukin-1 receptor–associated kinase 4 (IRAK4) and cyclic GMP-AMP synthase (cGAS) with IC50 of 2.8 nM and 2.1 nM, respectively.
S9945 G140 G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS), with IC50s of 14.0 nM and 442 nM for h-cGAS and m-cGAS, respectively.

cGAS阻害剤の選択性比較

Tags: cGAS inhibitor|cGAS agonist|cGAS activator|cGAS inducer|cGAS antagonist|cGAS signaling pathway|cGAS assay kit