cGAS

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S6841 RU.521 ˂1 mg/mL 83 mg/mL '2 mg/mL
S0775 IRAK4-IN-4 <1 mg/mL 68 mg/mL '''68 mg/mL
S8944 G150 <1 mg/mL 78 mg/mL 2 mg/mL

cGAS製品

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S6841

RU.521

RU.521 (RU320521) is an active, potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS) that inhibits the cGAS-mediated signaling with IC50 of 700 nM. RU.521 binds to the cGAS/dsDNA complex with Kd of 36.2 nM.

S0775

IRAK4-IN-4

IRAK4-IN-4 (compound 15) is an inhibitor of interleukin-1 receptor–associated kinase 4 (IRAK4) and cyclic GMP-AMP synthase (cGAS) with IC50 of 2.8 nM and 2.1 nM, respectively.

S8944

G150

G150 is a potent and highly selective human cyclic GMP-AMP synthase (cGAS) inhibitor with IC50 of 10.2 nM.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S6841

RU.521

RU.521 (RU320521) is an active, potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS) that inhibits the cGAS-mediated signaling with IC50 of 700 nM. RU.521 binds to the cGAS/dsDNA complex with Kd of 36.2 nM.

S0775

IRAK4-IN-4

IRAK4-IN-4 (compound 15) is an inhibitor of interleukin-1 receptor–associated kinase 4 (IRAK4) and cyclic GMP-AMP synthase (cGAS) with IC50 of 2.8 nM and 2.1 nM, respectively.

S8944

G150

G150 is a potent and highly selective human cyclic GMP-AMP synthase (cGAS) inhibitor with IC50 of 10.2 nM.