Fascin

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S2962

NP-G2-044 is a potent, orally active inhibitor of the actin-bundling activity of fascin with IC50 of ~0.2 μM. NP-G2-044 blocks tumor metastasis and increases antitumor immune response.

EMBO J, 2025, 10.1038/s44318-025-00515-z

bioRxiv, 2025, 2025.06.07.658418

Cancers (Basel), 2022, 14(11)2738

S2962

NP-G2-044 is a potent, orally active inhibitor of the actin-bundling activity of fascin with IC50 of ~0.2 μM. NP-G2-044 blocks tumor metastasis and increases antitumor immune response.

EMBO J, 2025, 10.1038/s44318-025-00515-z

bioRxiv, 2025, 2025.06.07.658418

Cancers (Basel), 2022, 14(11)2738