IL受容体

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S4028 Dexamethasone Sodium Phosphate 103 mg/mL <1 mg/mL <1 mg/mL
S5764 YM 90709 -1 mg/mL 47 mg/mL -1 mg/mL
S8562 CA-4948 <1 mg/mL 30 mg/mL <1 mg/mL
S1322 Dexamethasone <1 mg/mL 79 mg/mL 6 mg/mL
S3124 Dexamethasone Acetate <1 mg/mL 87 mg/mL 20 mg/mL

IL Receptor製品

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
A2011

Sarilumab (anti-IL-6Rα)

Sarilumab is a fully human anti-IL-6Rα mAb that binds membrane-bound and soluble human IL-6Rα with high affinity, MW: 144.13 KD.

A2012

Tocilizumab (anti-IL-6R)

Tocilizumab is a humanized monoclonal antibody that binds to the interleukin-6 receptor, MW: 148 KD.

S4028

Dexamethasone Sodium Phosphate

Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.

S5764

YM 90709

YM 90709 is a novel IL-5 inhibitor which selectively blocks the binding of IL-5 to the IL-5 receptor (IL-5R).

S8562

CA-4948

CA-4948 is a reversible kinase inhibitor that modulates IRAK4 function in both the toll-like receptor (TLR) and interleukin 1 receptor (IL-1R) signaling cascades, and demonstrates pharmacodynamic and antitumor activity in in vitro and in vivo nonclinical models. CA-4948 also inhibits FLT3.

S1322

Dexamethasone

Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects. Dexamethasone induces autophagy and mitophagy. Dexamethasone is tested in hospitalized patients with COVID-19 and is found to have benefits for critically ill patients.

S3124

Dexamethasone Acetate

Dexamethasone (NSC 39471) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
A2011

Sarilumab (anti-IL-6Rα)

Sarilumab is a fully human anti-IL-6Rα mAb that binds membrane-bound and soluble human IL-6Rα with high affinity, MW: 144.13 KD.

A2012

Tocilizumab (anti-IL-6R)

Tocilizumab is a humanized monoclonal antibody that binds to the interleukin-6 receptor, MW: 148 KD.

S4028

Dexamethasone Sodium Phosphate

Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.

S5764

YM 90709

YM 90709 is a novel IL-5 inhibitor which selectively blocks the binding of IL-5 to the IL-5 receptor (IL-5R).

S8562

CA-4948

CA-4948 is a reversible kinase inhibitor that modulates IRAK4 function in both the toll-like receptor (TLR) and interleukin 1 receptor (IL-1R) signaling cascades, and demonstrates pharmacodynamic and antitumor activity in in vitro and in vivo nonclinical models. CA-4948 also inhibits FLT3.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S1322

Dexamethasone

Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects. Dexamethasone induces autophagy and mitophagy. Dexamethasone is tested in hospitalized patients with COVID-19 and is found to have benefits for critically ill patients.

2020, 10.1158/1078-0432.CCR-20-1315

2020, 10(6):72

2020, 16(4):543-552

S3124

Dexamethasone Acetate

Dexamethasone (NSC 39471) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.

2020, 10(6):72

2020, 1-10

2020, 48(8):613-621