IL受容体

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S4028 Dexamethasone Sodium Phosphate 103 mg/mL <1 mg/mL <1 mg/mL
S2015 Suplatast Tosylate 100 mg/mL 100 mg/mL 100 mg/mL
S5764 YM 90709 -1 mg/mL 47 mg/mL -1 mg/mL
S2039 IRAK inhibitor 6 <1 mg/mL 7 mg/mL <1 mg/mL
S8531 PF-06650833 <1 mg/mL 72 mg/mL 3 mg/mL
S6598 IRAK-1-4 Inhibitor I <1 mg/mL 11 mg/mL <1 mg/mL
S4267 Diacerein <1 mg/mL 48 mg/mL <1 mg/mL
S8562 CA-4948 <1 mg/mL 30 mg/mL <1 mg/mL
S8696 2-D08 <1 mg/mL 54 mg/mL <1 mg/mL
S1322 Dexamethasone <1 mg/mL 79 mg/mL 6 mg/mL
S3124 Dexamethasone Acetate <1 mg/mL 87 mg/mL 20 mg/mL

IL Receptor製品

新IL Receptor製品
製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
A2011

Sarilumab

Sarilumab is a fully human anti-IL-6Rα mAb that binds membrane-bound and soluble human IL-6Rα with high affinity, MW: 144.13 KD.

A2012

Tocilizumab

Tocilizumab is a humanized monoclonal antibody that binds to the interleukin-6 receptor, MW: 148 KD.

S4028

Dexamethasone Sodium Phosphate

Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.

S2015

Suplatast Tosylate

Suplatast Tosilate is a novel capsular anti-asthmatic agent that suppresses both IgE production, IL-4 and IL-5 synthesis with IC50 above 100 μM.

S5764

YM 90709

YM 90709 is a novel IL-5 inhibitor which selectively blocks the binding of IL-5 to the IL-5 receptor (IL-5R).

S2039

IRAK inhibitor 6

IRAK inhibitor 6 is a selective Interleukin-1 receptor-associated kinase 4(IRAK4) inhibitor with IC50 of 0.16 μM.

S8531

PF-06650833

PF-06650833 is a potent, selective inhibitor of IRAK4 with an IC50 of 0.2 nM.

S6598

IRAK-1-4 Inhibitor I

IRAK-1-4 Inhibitor I is an inhibitor of interleukin-1 receptor associated kinase (IRAK) with IC50 values of 0.3 μM and 0.2 μM for IRAK-1 and IRAK-4, respectively. It displays IC50 values >10 µM in a panel of 27 other kinases tested.

S4267

Diacerein

Diacerein is an inhibitor of pro-inflammatory cytokine Interleukin-1B (IL-1B) production, prescribed for osteoarthritis and chronic inflammatory arthritis.

S8562

CA-4948

CA-4948 is a reversible kinase inhibitor that modulates IRAK4 function in both the toll-like receptor (TLR) and interleukin 1 receptor (IL-1R) signaling cascades, and demonstrates pharmacodynamic and antitumor activity in in vitro and in vivo nonclinical models.

S8696

2-D08

2-D08 is a cell permeable, mechanistically unique inhibitor of protein sumoylation. It is also inhibits Axl, IRAK4, ROS1, MLK4, GSK3β, RET, KDR and PI3Kα with IC50 values of 0.49, 3.9, 5.3, 9.8, 11, 11, 17 and 35 nM respectively in biochemical assays.

S1322

Dexamethasone

Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.

S3124

Dexamethasone Acetate

Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
A2011

Sarilumab

Sarilumab is a fully human anti-IL-6Rα mAb that binds membrane-bound and soluble human IL-6Rα with high affinity, MW: 144.13 KD.

A2012

Tocilizumab

Tocilizumab is a humanized monoclonal antibody that binds to the interleukin-6 receptor, MW: 148 KD.

S4028

Dexamethasone Sodium Phosphate

Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.

S2015

Suplatast Tosylate

Suplatast Tosilate is a novel capsular anti-asthmatic agent that suppresses both IgE production, IL-4 and IL-5 synthesis with IC50 above 100 μM.

S5764

YM 90709

YM 90709 is a novel IL-5 inhibitor which selectively blocks the binding of IL-5 to the IL-5 receptor (IL-5R).

S2039

IRAK inhibitor 6

IRAK inhibitor 6 is a selective Interleukin-1 receptor-associated kinase 4(IRAK4) inhibitor with IC50 of 0.16 μM.

S8531

PF-06650833

PF-06650833 is a potent, selective inhibitor of IRAK4 with an IC50 of 0.2 nM.

S6598

IRAK-1-4 Inhibitor I

IRAK-1-4 Inhibitor I is an inhibitor of interleukin-1 receptor associated kinase (IRAK) with IC50 values of 0.3 μM and 0.2 μM for IRAK-1 and IRAK-4, respectively. It displays IC50 values >10 µM in a panel of 27 other kinases tested.

S4267

Diacerein

Diacerein is an inhibitor of pro-inflammatory cytokine Interleukin-1B (IL-1B) production, prescribed for osteoarthritis and chronic inflammatory arthritis.

S8562

CA-4948

CA-4948 is a reversible kinase inhibitor that modulates IRAK4 function in both the toll-like receptor (TLR) and interleukin 1 receptor (IL-1R) signaling cascades, and demonstrates pharmacodynamic and antitumor activity in in vitro and in vivo nonclinical models.

S8696

2-D08

2-D08 is a cell permeable, mechanistically unique inhibitor of protein sumoylation. It is also inhibits Axl, IRAK4, ROS1, MLK4, GSK3β, RET, KDR and PI3Kα with IC50 values of 0.49, 3.9, 5.3, 9.8, 11, 11, 17 and 35 nM respectively in biochemical assays.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S1322

Dexamethasone

Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.

2019, 9(5):628-645

2019, 10.1158/1078-0432

2019, 10.1016/j.ymthe.2019.08.011

S3124

Dexamethasone Acetate

Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.

2018, 390:151-159

2015, 6:8481