LATS antagonist | LATS inhibitor | LATS agonist |LATS activator

製品コード	製品名称	製品説明	文献中Selleckの製品使用例
E1314	TDI-011536	TDI-011536 is a potent Lats kinase inhibitor that interrupts Hippo-Yap signaling and promotes proliferation of lesioned cardiac muscle cells.	Nat Commun, 2024, 15(1):6953 Int J Mol Sci, 2024, 25(20)11234 bioRxiv, 2024, 2024.10.11.617852
F2952^New	LATS1/WARTS Antibody [F14J12]
E1061	TRULI	TRULI inhibits both Lats1 and Lats2 with a IC50 of 0.2 nM, suppresses Yap phosphorylation, induces cell proliferation in several cell lines and tissues, and promotes the initial stages of proliferative regeneration of the sensory receptors in the inner ear.	Cell, 2025, S0092-8674(25)00807-4 Nat Commun, 2024, 15(1):5449 Cell Rep, 2024, 43(4):114032
E1145	GA-017	GA-017 inhibits the serine/threonine protein kinases large tumor suppressor kinase 1/2 (LATS1/2), which exerts inhibitory with IC50s against LATS1 and 2 of 4.10±0.79 and 3.92±0.42 nM, respectively, and competitively inhibits LATS1 and 2 against ATP, with Ki (inhibition constant) values of 0.58±0.11 and 0.25±0.03 nM, respectively.	Nat Cell Biol, 2025, NONE
F0232^New	LATS1 Antibody [A5C10]	LATS1,LATS1/WARTS
E1314	TDI-011536	TDI-011536 is a potent Lats kinase inhibitor that interrupts Hippo-Yap signaling and promotes proliferation of lesioned cardiac muscle cells.	Nat Commun, 2024, 15(1):6953 Int J Mol Sci, 2024, 25(20)11234 bioRxiv, 2024, 2024.10.11.617852
E1061	TRULI	TRULI inhibits both Lats1 and Lats2 with a IC50 of 0.2 nM, suppresses Yap phosphorylation, induces cell proliferation in several cell lines and tissues, and promotes the initial stages of proliferative regeneration of the sensory receptors in the inner ear.	Cell, 2025, S0092-8674(25)00807-4 Nat Commun, 2024, 15(1):5449 Cell Rep, 2024, 43(4):114032
E1145	GA-017	GA-017 inhibits the serine/threonine protein kinases large tumor suppressor kinase 1/2 (LATS1/2), which exerts inhibitory with IC50s against LATS1 and 2 of 4.10±0.79 and 3.92±0.42 nM, respectively, and competitively inhibits LATS1 and 2 against ATP, with Ki (inhibition constant) values of 0.58±0.11 and 0.25±0.03 nM, respectively.	Nat Cell Biol, 2025, NONE
F2952^New	LATS1/WARTS Antibody [F14J12]
F0232^New	LATS1 Antibody [A5C10]	LATS1,LATS1/WARTS

LATS

LATS製品