Mechanosensitive Channel antagonist | Mechanosensitive Channel inhibitor | Mechanosensitive Channel agonist

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Specific Compounds Quantities 96 or 384 well Plate Map Dry/solid or DMSO solution

抗体

製品コード	製品名称	製品説明	文献中Selleckの製品使用例
S6678	Yoda1	Yoda1 acts as an agonist for both human and mouse Piezo1(EC50 of 17.1 and 26.6 μM for mouse and human). Yoda1 activates purified Piezo1 channels in the absence of other cellular components.	Int J Mol Sci, 2023, 24(7)6720 J Innate Immun, 2023, 15(1):709-23 Sci Adv, 2023, 9(22):eadg0478
S2953	Dooku1	Dooku1 is an analog of Yoda1 with antagonist activity against mechanosensitive Piezo1 channel. Dooku1 inhibits 2 μM Yoda1-induced Ca²⁺-entry with IC50 of 1.3 μM in HEK 293 cells and 1.5 μM in HUVECs, respectively.	Sci Adv, 2023, 9(22):eadg0478
S6678	Yoda1	Yoda1 acts as an agonist for both human and mouse Piezo1(EC50 of 17.1 and 26.6 μM for mouse and human). Yoda1 activates purified Piezo1 channels in the absence of other cellular components.	Int J Mol Sci, 2023, 24(7)6720 J Innate Immun, 2023, 15(1):709-23 Sci Adv, 2023, 9(22):eadg0478
S2953	Dooku1	Dooku1 is an analog of Yoda1 with antagonist activity against mechanosensitive Piezo1 channel. Dooku1 inhibits 2 μM Yoda1-induced Ca²⁺-entry with IC50 of 1.3 μM in HEK 293 cells and 1.5 μM in HUVECs, respectively.	Sci Adv, 2023, 9(22):eadg0478
S6678	Yoda1	Yoda1 acts as an agonist for both human and mouse Piezo1(EC50 of 17.1 and 26.6 μM for mouse and human). Yoda1 activates purified Piezo1 channels in the absence of other cellular components.	Int J Mol Sci, 2023, 24(7)6720 J Innate Immun, 2023, 15(1):709-23 Sci Adv, 2023, 9(22):eadg0478

Mechanosensitive Channel

Mechanosensitive Channel製品

Mechanosensitive Channel阻害剤の選択性比較