p97

シグナル伝達経路

研究分野

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S7285 NMS-873 <1 mg/mL 100 mg/mL <1 mg/mL
S7199 DBeQ <1 mg/mL 68 mg/mL 5 mg/mL
S4921 MNS (3,4-Methylenedioxy-β-nitrostyrene) <1 mg/mL 39 mg/mL <1 mg/mL
S8101 CB-5083 <1 mg/mL 82 mg/mL 13 mg/mL
S4453 NPD8733 <1 mg/mL 31 mg/mL '''<1 mg/mL

p97製品

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S7285

NMS-873

NMS-873 is an allosteric and specific p97 inhibitor with IC50 of 30 nM that demonstrates potent selectivity for VCP/p97 compared to a panel of other AAA ATPases, Hsp90, and 53 additional analyzed kinases (IC50s >10 μM).

S7199

DBeQ

DBeQ (JRF 12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor with IC50 of 1.5 μM.

S4921

MNS (3,4-Methylenedioxy-β-nitrostyrene)

MNS is a tyrosine kinase inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.

S8101

CB-5083

CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor with IC50 of 11 nM. Phase 1.

S4453

NPD8733

NPD8733 is an inhibitor of cancer cell-enhanced fibroblast migration that specifically binds to valosin-containing protein (VCP)/p97, a member of the ATPase-associated with diverse cellular activities (AAA+) protein family.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S7285

NMS-873

NMS-873 is an allosteric and specific p97 inhibitor with IC50 of 30 nM that demonstrates potent selectivity for VCP/p97 compared to a panel of other AAA ATPases, Hsp90, and 53 additional analyzed kinases (IC50s >10 μM).

S7199

DBeQ

DBeQ (JRF 12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor with IC50 of 1.5 μM.

S4921

MNS (3,4-Methylenedioxy-β-nitrostyrene)

MNS is a tyrosine kinase inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.

S8101

CB-5083

CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor with IC50 of 11 nM. Phase 1.

S4453

NPD8733

NPD8733 is an inhibitor of cancer cell-enhanced fibroblast migration that specifically binds to valosin-containing protein (VCP)/p97, a member of the ATPase-associated with diverse cellular activities (AAA+) protein family.