Parasite

阻害剤の選択性比較

カタログ番号	製品カタログ	溶解度(25°C)
カタログ番号	製品カタログ	水	DMSO	アルコール
S2468	Fenbendazole	<1 mg/mL	4 mg/mL	'<1 mg/mL
S1837	Flubendazole	<1 mg/mL	3 mg/mL	'<1 mg/mL
S7379	E-64	11 mg/mL	71 mg/mL	''<1 mg/mL
S4044	Toltrazuril	<1 mg/mL	85 mg/mL	'<1 mg/mL
S3741	Benznidazole	<1 mg/mL	52 mg/mL	''5 mg/mL
S3591	Eprinomectin	<1 mg/mL	100 mg/mL	'''100 mg/mL
S4422	Nitenpyram	54 mg/mL	54 mg/mL	'54 mg/mL
S0081	DDD107498 succinate			' mg/mL
S3889	Arteether	-1 mg/mL	62 mg/mL	''-1 mg/mL
S5557	Aklomide	-1 mg/mL	40 mg/mL	'-1 mg/mL
S4564	Diethylcarbamazine citrate	78 mg/mL	78 mg/mL	''30 mg/mL
S5247	Selamectin	-1 mg/mL	100 mg/mL	''-1 mg/mL

Parasite製品

All (12) Parasite阻害剤(12)

製品コード	製品説明	文献中Selleckの製品使用例	お客様のフィードバック
S2468	Fenbendazole Fenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites with an IC50 of about 0.01 μg/mL.
S1837	Flubendazole Flubendazole (Flumoxanal, NSC 313680) is an autophagy inducer by targeting Atg4B, used to treat internal parasite and worm infection.	Sci Rep, 2020, 10(1):13124 RSC Advances, 2018, 10.1039/C7RA12259D	Inhibitory curves and IC50 values for the reference compound flubendazole (B) against VEGFR2.
S7379	E-64 E-64 is an irreversible and selective cysteine protease inhibitor, and also inhibits papain, calpain, and cathepsins B and H, but not serine proteases or aspartic proteases. The IC50 for papain is 9 nM. E-64 induces oxidative stress and apoptosis in Filarial Parasite.	Sci Adv, 2021, 7(3)eabc6364 Bioorg Med Chem, 2021, 35:116055 J Am Soc Nephrol, 2020, 31(2):374-391
S4044	Toltrazuril Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites.
S3741	Benznidazole Benznidazole (Radanil) is a nitroimidazole derivative having an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and stimulating host phagocytosis.
S3591^新	Eprinomectin Eprinomectin (EPM, MK-397) is an excellent broad-spectrum endectocide with anthelmintic, insecticidal and miticidal activity.
S4422	Nitenpyram Nitenpyram is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets.	Proc Natl Acad Sci U S A, 2020, 117(21):11321-11327
S0081	DDD107498 succinate DDD107498 succinate (M-5717, DDD-498 succinate) is a potent and orally active antimalarial agent. DDD107498 succinate inhibits multiple life-cycle stages of the parasite with EC50 of 1 nM against P. falciparum 3D7. DDD107498 succinate inhibits protein synthesis by targeting eEF2/CaMKIII with EC50 of 2 nM for WT-PfeEF2.
S3889	Arteether Arteether is a well-known antimalarial drug which acts by producing free radicals within the malarial parasite.	ACS Infect Dis, 2020, 10.1021/acsinfecdis.0c00522
S5557	Aklomide Aklomide (2-Chloro-4-nitrobenzamide) is a coccidiostat and used to fight disease, parasites and insects that infest poultry.
S4564	Diethylcarbamazine citrate Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria and is highly specific for several parasites and does not contain any toxic metallic elements.
S5247	Selamectin Selamectin (UK-124114) is a novel macrocyclic lactone of the avermectin class. It paralyses and/or kills a wide range of invertebrate parasites through interference with their chloride channel conductance causing disruption of normal neurotransmission and has adulticidal, ovicidal and larvicidal activity against fleas.

製品コード	製品説明	文献中Selleckの製品使用例	お客様のフィードバック
S2468	Fenbendazole Fenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites with an IC50 of about 0.01 μg/mL.
S1837	Flubendazole Flubendazole (Flumoxanal, NSC 313680) is an autophagy inducer by targeting Atg4B, used to treat internal parasite and worm infection.	Sci Rep, 2020, 10(1):13124 RSC Advances, 2018, 10.1039/C7RA12259D	Inhibitory curves and IC50 values for the reference compound flubendazole (B) against VEGFR2.
S7379	E-64 E-64 is an irreversible and selective cysteine protease inhibitor, and also inhibits papain, calpain, and cathepsins B and H, but not serine proteases or aspartic proteases. The IC50 for papain is 9 nM. E-64 induces oxidative stress and apoptosis in Filarial Parasite.	Sci Adv, 2021, 7(3)eabc6364 Bioorg Med Chem, 2021, 35:116055 J Am Soc Nephrol, 2020, 31(2):374-391
S4044	Toltrazuril Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites.
S3741	Benznidazole Benznidazole (Radanil) is a nitroimidazole derivative having an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and stimulating host phagocytosis.
S3591^新	Eprinomectin Eprinomectin (EPM, MK-397) is an excellent broad-spectrum endectocide with anthelmintic, insecticidal and miticidal activity.
S4422	Nitenpyram Nitenpyram is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets.	Proc Natl Acad Sci U S A, 2020, 117(21):11321-11327
S0081	DDD107498 succinate DDD107498 succinate (M-5717, DDD-498 succinate) is a potent and orally active antimalarial agent. DDD107498 succinate inhibits multiple life-cycle stages of the parasite with EC50 of 1 nM against P. falciparum 3D7. DDD107498 succinate inhibits protein synthesis by targeting eEF2/CaMKIII with EC50 of 2 nM for WT-PfeEF2.
S3889	Arteether Arteether is a well-known antimalarial drug which acts by producing free radicals within the malarial parasite.	ACS Infect Dis, 2020, 10.1021/acsinfecdis.0c00522
S5557	Aklomide Aklomide (2-Chloro-4-nitrobenzamide) is a coccidiostat and used to fight disease, parasites and insects that infest poultry.
S4564	Diethylcarbamazine citrate Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria and is highly specific for several parasites and does not contain any toxic metallic elements.
S5247	Selamectin Selamectin (UK-124114) is a novel macrocyclic lactone of the avermectin class. It paralyses and/or kills a wide range of invertebrate parasites through interference with their chloride channel conductance causing disruption of normal neurotransmission and has adulticidal, ovicidal and larvicidal activity against fleas.