Parasite
阻害剤の選択性比較
| カタログ番号 | 製品カタログ | 溶解度(25°C) | ||
|---|---|---|---|---|
| 水 | DMSO | アルコール | ||
| S2468 | Fenbendazole | <1 mg/mL | 4 mg/mL | '<1 mg/mL |
| S1837 | Flubendazole | <1 mg/mL | 3 mg/mL | '<1 mg/mL |
| S7379 | E-64 | 11 mg/mL | 71 mg/mL | '<1 mg/mL |
| S4044 | Toltrazuril | <1 mg/mL | 85 mg/mL | '<1 mg/mL |
| S3741 | Benznidazole | <1 mg/mL | 52 mg/mL | ''5 mg/mL |
| S0081 | DDD107498 succinate | ' mg/mL | ||
| S4422 | Nitenpyram | 54 mg/mL | 54 mg/mL | '54 mg/mL |
| S3889 | Arteether | -1 mg/mL | 62 mg/mL | ''-1 mg/mL |
| S5557 | Aklomide | -1 mg/mL | 40 mg/mL | '-1 mg/mL |
| S4564 | Diethylcarbamazine citrate | 78 mg/mL | 78 mg/mL | ''30 mg/mL |
| S5247 | Selamectin | -1 mg/mL | 100 mg/mL | ''-1 mg/mL |
Parasite製品
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| S2468 |
FenbendazoleFenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites with an IC50 of about 0.01 μg/mL. |
||
| S1837 |
FlubendazoleFlubendazole (Flumoxanal, NSC 313680) is an autophagy inducer by targeting Atg4B, used to treat internal parasite and worm infection. |
Inhibitory curves and IC50 values for the reference compound flubendazole (B) against VEGFR2.
|
|
| S7379 |
E-64E-64 is an irreversible and selective cysteine protease inhibitor, and also inhibits papain, calpain, and cathepsins B and H, but not serine proteases or aspartic proteases. The IC50 for papain is 9 nM. E-64 induces oxidative stress and apoptosis in Filarial Parasite. |
||
| S4044 |
ToltrazurilToltrazuril is an antiprotozoal agent that acts upon Coccidia parasites. |
||
| S3741 |
BenznidazoleBenznidazole (Radanil) is a nitroimidazole derivative having an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and stimulating host phagocytosis. |
||
| S0081新 |
DDD107498 succinateDDD107498 succinate (DDD-498 succinate) is a potent and orally active antimalarial agent. DDD107498 succinate inhibits multiple life-cycle stages of the parasite with EC50 of 1 nM against P. falciparum 3D7. DDD107498 succinate inhibits protein synthesis by targeting eEF2/CaMKIII with EC50 of 2 nM for WT-PfeEF2. |
||
| S4422 |
NitenpyramNitenpyram is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets. |
||
| S3889 |
ArteetherArteether is a well-known antimalarial drug which acts by producing free radicals within the malarial parasite. |
||
| S5557 |
AklomideAklomide (2-Chloro-4-nitrobenzamide) is a coccidiostat and used to fight disease, parasites and insects that infest poultry. |
||
| S4564 |
Diethylcarbamazine citrateDiethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria and is highly specific for several parasites and does not contain any toxic metallic elements. |
||
| S5247 |
SelamectinSelamectin (UK-124114) is a novel macrocyclic lactone of the avermectin class. It paralyses and/or kills a wide range of invertebrate parasites through interference with their chloride channel conductance causing disruption of normal neurotransmission and has adulticidal, ovicidal and larvicidal activity against fleas. |
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| S2468 |
FenbendazoleFenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites with an IC50 of about 0.01 μg/mL. |
||
| S1837 |
FlubendazoleFlubendazole (Flumoxanal, NSC 313680) is an autophagy inducer by targeting Atg4B, used to treat internal parasite and worm infection. |
Inhibitory curves and IC50 values for the reference compound flubendazole (B) against VEGFR2.
|
|
| S7379 |
E-64E-64 is an irreversible and selective cysteine protease inhibitor, and also inhibits papain, calpain, and cathepsins B and H, but not serine proteases or aspartic proteases. The IC50 for papain is 9 nM. E-64 induces oxidative stress and apoptosis in Filarial Parasite. |
||
| S4044 |
ToltrazurilToltrazuril is an antiprotozoal agent that acts upon Coccidia parasites. |
||
| S3741 |
BenznidazoleBenznidazole (Radanil) is a nitroimidazole derivative having an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and stimulating host phagocytosis. |
||
| S0081新 |
DDD107498 succinateDDD107498 succinate (DDD-498 succinate) is a potent and orally active antimalarial agent. DDD107498 succinate inhibits multiple life-cycle stages of the parasite with EC50 of 1 nM against P. falciparum 3D7. DDD107498 succinate inhibits protein synthesis by targeting eEF2/CaMKIII with EC50 of 2 nM for WT-PfeEF2. |
||
| S4422 |
NitenpyramNitenpyram is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets. |
||
| S3889 |
ArteetherArteether is a well-known antimalarial drug which acts by producing free radicals within the malarial parasite. |
||
| S5557 |
AklomideAklomide (2-Chloro-4-nitrobenzamide) is a coccidiostat and used to fight disease, parasites and insects that infest poultry. |
||
| S4564 |
Diethylcarbamazine citrateDiethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria and is highly specific for several parasites and does not contain any toxic metallic elements. |
||
| S5247 |
SelamectinSelamectin (UK-124114) is a novel macrocyclic lactone of the avermectin class. It paralyses and/or kills a wide range of invertebrate parasites through interference with their chloride channel conductance causing disruption of normal neurotransmission and has adulticidal, ovicidal and larvicidal activity against fleas. |
