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gp91ds-tat

gp91ds-tat, a peptide inhibitor for NADPH oxidase assembly, is composed of gp91phox sequence linked to the human immunodeficiency virus-tat peptide. The tat sequence facilitates the entry of this peptide into cells.

Amino-acid Sequence

gp91ds-tat化学構造

CAS No.

サイズ 価格(税別) 在庫状況
5mg JPY 22000 国内在庫あり
25mg JPY 62500 国内在庫あり
100mg JPY 145500 お問い合わせ
1g JPY 598500 お問い合わせ
バルクサイズ バルク特価あり

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製品安全説明書

現在のバッチを見る： P121301 Water] 49 mg/mL] false] ] ] false] ] ] false 純度： 99.95%
99.95

化学情報

保管 3 years-20°C powder

In vitro
Batch:

Water : 49 mg/mL

モル濃度計算器

in vivo
Batch:

Add solvents to the product individually and in order.

投与溶液組成計算機

生物活性

製品説明 gp91ds-tat, a peptide inhibitor for NADPH oxidase assembly, is composed of gp91phox sequence linked to the human immunodeficiency virus-tat peptide. The tat sequence facilitates the entry of this peptide into cells.
Targets
NADPH oxidase
In vitro
In vitro

Gp91ds-tat, an inhibitor of NOX (NADPH oxidase) 2, can prevented high extracellular glucose (Hi-Glu)/Thiamet G (ThmG)-induced ROS generation.
In Vivo
In vivo

Gp91ds-tat can attenuate cerebral I/R injury in a rat model of middle cerebral artery occlusion (MCAO) through reducing ROS levels, inhibiting neuronal apoptosis and degeneration, and alleviating BBB damage.
動物実験 動物モデル middle cerebral artery occlusion (MCAO) model rats
投与量 100 ng/kg
投与経路 infused into the ventricle
  • https://pubmed.ncbi.nlm.nih.gov/12861025/
  • https://pubmed.ncbi.nlm.nih.gov/32134364/
  • https://pubmed.ncbi.nlm.nih.gov/31407062/

製品情報

Molecular Formula

C109H202N52O25S1
Molecular Weight 2673.3
Appearance White Powder
Peptide Content (by %N) ≥80%
Single Impurity (by HPLC) ≤1.0%
Assay (By Anhydrous, Acetic Acid-free) 95.0~105.0%
MS Consistent
Packing plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement.
Storage
(From the date of receipt)		 3 years-20°C powder
Shipping Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
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