PERK

  • 阻害剤の選択性比較
  • 溶解度
カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S7307 GSK2606414 <1 mg/mL 90 mg/mL 19 mg/mL
S7033 GSK2656157 <1 mg/mL 32 mg/mL <1 mg/mL
S7400 ISRIB (trans-isomer) <1 mg/mL 4 mg/mL <1 mg/mL
S7307 GSK2606414 <1 mg/mL 90 mg/mL 19 mg/mL
S7033 GSK2656157 <1 mg/mL 32 mg/mL <1 mg/mL
S7400 ISRIB (trans-isomer) <1 mg/mL 4 mg/mL <1 mg/mL
製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S7307

GSK2606414

GSK2606414 is an orally available, potent, and selective PERK inhibitor with IC50 of 0.4 nM, displaying at least 100-fold selectivity over the other EIF2AKs assayed.

S7033

GSK2656157

GSK2656157 is an ATP-competitive and highly selective inhibitor of PERK with IC50 of 0.9 nM in a cell-free assay, 500-fold greater against a panel of 300 kinases.

S7400

ISRIB (trans-isomer)

ISRIB (trans-isomer), the trans-isomer of ISRIB, is a potent and selective PERK inhibitor with IC50 of 5 nM and does not have global effects on translation, transcription, or mRNA stability in non-stressed cells.

S7307

GSK2606414

GSK2606414 is an orally available, potent, and selective PERK inhibitor with IC50 of 0.4 nM, displaying at least 100-fold selectivity over the other EIF2AKs assayed.

S7033

GSK2656157

GSK2656157 is an ATP-competitive and highly selective inhibitor of PERK with IC50 of 0.9 nM in a cell-free assay, 500-fold greater against a panel of 300 kinases.

S7400

ISRIB (trans-isomer)

ISRIB (trans-isomer), the trans-isomer of ISRIB, is a potent and selective PERK inhibitor with IC50 of 5 nM and does not have global effects on translation, transcription, or mRNA stability in non-stressed cells.