Docetaxel

For research use only. Not for use in humans.

製品コードS1148 別名:RP56976, NSC 628503

Docetaxel化学構造

分子量(MW):807.88

Docetaxel, an analog of paclitaxel, is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules.

サイズ 価格(税別) 在庫  
10mM (1mL in DMSO) JPY 17100 あり
JPY 13600 あり
JPY 46800 あり
最寄りの販売代理店を探す

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バルク問合せ

文献中Selleckの製品使用例(56)

製品安全説明書

Microtubule Associated阻害剤の選択性比較

生物活性

製品説明 Docetaxel, an analog of paclitaxel, is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules.
ターゲット
Microtubules [1]
(Cell-free assay)
体外試験

Docetaxel is a cytotoxic agent, especially for proliferating cells, which is related to its ability to promote the formation of microtubule bundles and induce sustained mitotic arrest, followed by apoptosis of mitotically arrested cells or permanent mitotic block. Docetaxel suppresses microtubule dynamic instability as well as tread-milling, resulting in the failure of chromosomes to segregate to the daughter cells, which in turn triggers premature exit from mitosis rather than a block at this phase of the cell cycle. [2] Docetaxel inhibits the clonogenic survival of Human cancer cell Hs746T (stomach), AGS (stomach), HeLa (cervix), CaSki (cervix), BxPC3 (pancreas), Capan-1 (pancreas) with IC50 of 1 nM, 1 nM, 0.3 nM, 0.3 nM, 0.3 nM and 0.3 nM respectively. [4] Docetaxel inhibits endothelial cell migration that does not affects microtubule gross morphology or inhibit cell proliferation, although they does produce more subtle effects on microtubule dynamics. Docetaxel inhibits HUVEC migration with an observed IC50 of 1 pM. HUVEC chemotaxis stimulated by either of two angiogenic factors, thymidine phosphorylase or VEGF, is inhibited by Docetaxel with IC 50 of 10 pM and is ablated at 1 nM. [7] Docetaxel induces human monocytes, but not RAW 264.7 murine macrophages, Prostaglandin H Synthase-2m (PGHS-2) expression. [8]

細胞データ
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
HSC-3 M2jCSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIDmbIRKSzVyPUCuNFAxOTN{IN88US=> NWXaZ5Z4W0GQR1XS
5637 M3XrfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3TTNWlEPTB;MD6wNFAyPDNizszN MWnTRW5ITVJ?
HT-144 M4j4V2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV3JR|UxRTBwMECwNVU4KM7:TR?= NUfvb|ZHW0GQR1XS
NCI-H292 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MW\JR|UxRTBwMECwNVU6KM7:TR?= M2fJbnNCVkeHUh?=
HCE-T M{W3UGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4LNWmlEPTB;MD6wNFAyPjJizszN M3LjVnNCVkeHUh?=
ESS-1 NUGxWY1lT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml;jTWM2OD1yLkCwNFE4QSEQvF2= M4PvNHNCVkeHUh?=
D-566MG M4jyfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2T6SGlEPTB;MD6wNFAyQDJizszN M2jsWXNCVkeHUh?=
CAL-62 NXjjVI5nT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWPRS2c6UUN3ME2wMlAxODF6NTFOwG0> M{jBPHNCVkeHUh?=
GT3TKB NHSwd5pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mo\STWM2OD1yLkCwNFI{OiEQvF2= MXLTRW5ITVJ?
HSC-4 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVLMWGZlUUN3ME2wMlAxODJ|OTFOwG0> MVfTRW5ITVJ?
KOSC-2 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX7nXGRVUUN3ME2wMlAxODJ3NTFOwG0> MULTRW5ITVJ?
NB14 NWK2TIJoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWnlUWhVUUN3ME2wMlAxODJ4IN88US=> MV;TRW5ITVJ?
ES8 M1vFRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkjiTWM2OD1yLkCwNFI3KM7:TR?= M4DXSnNCVkeHUh?=
BFTC-905 MmDvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFPrRZBKSzVyPUCuNFAxOjZ6IN88US=> NELYdJNUSU6JRWK=
A498 NYjPdINlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3[yTmlEPTB;MD6wNFAzPzhizszN NW\6NGpLW0GQR1XS
HO-1-N-1 NWXsOpNKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MY\JR|UxRTBwMECwNlgyKM7:TR?= MWDTRW5ITVJ?
SF539 NID3VnBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkDrTWM2OD1yLkCwNFMxOiEQvF2= Mn\TV2FPT0WU
HuO-3N1 M1vCdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4f6XmlEPTB;MD6wNFA{ODJizszN M2fqTXNCVkeHUh?=
NCI-H510A NFfJVGVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUTJR|UxRTBwMECwN|M3KM7:TR?= NWj1fpR7W0GQR1XS
CAL-27 NYD1W2M1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MULJR|UxRTBwMECwN|M6KM7:TR?= MWXTRW5ITVJ?
TE-8 M{HSdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4\n[GlEPTB;MD6wNFA{PjZizszN MXnTRW5ITVJ?
VA-ES-BJ MoSwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3vG[GlEPTB;MD6wNFA{PzVizszN MUjTRW5ITVJ?
RH-1 M1TNV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4T6U2lEPTB;MD6wNFA{QDZizszN NWqwfIg6W0GQR1XS
COLO-800 NVnKOHNJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX\JR|UxRTBwMECwN|g5KM7:TR?= MVXTRW5ITVJ?
ES7 MnT6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkT2TWM2OD1yLkCwNFM5QSEQvF2= NGXrUXFUSU6JRWK=
GAMG Mk\OS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnfWTWM2OD1yLkCwNFQyPiEQvF2= MlTTV2FPT0WU
Ca9-22 MlnUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1fCSWlEPTB;MD6wNFA1OjNizszN M3rFb3NCVkeHUh?=
SBC-1 MlnMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmLGTWM2OD1yLkCwNFQ{KM7:TR?= MmrTV2FPT0WU
RPMI-7951 M1G5bmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVzJR|UxRTBwMECwOFQ5KM7:TR?= MoLYV2FPT0WU
SW1710 Mnf5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NULjcXAyUUN3ME2wMlAxODR4NjFOwG0> MU\TRW5ITVJ?
HGC-27 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYHJR|UxRTBwMECwOFcyKM7:TR?= NVez[3ljW0GQR1XS
MC-IXC MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUnJR|UxRTBwMECwOFc6KM7:TR?= MXvTRW5ITVJ?
FTC-133 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYLoeoJXUUN3ME2wMlAxODR6OTFOwG0> MX;TRW5ITVJ?
HT-1080 Mn3QS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVnHVI5JUUN3ME2wMlAxODVyMTFOwG0> NUXpb|d7W0GQR1XS
NMC-G1 M{TiNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYTJR|UxRTBwMECwOVE4KM7:TR?= NFXGbHlUSU6JRWK=
GI-1 NVf3NGJ{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX7WN3RlUUN3ME2wMlAxODV{ODFOwG0> NYPxS|JpW0GQR1XS
CGTH-W-1 NVzaOWxQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3XDUGlEPTB;MD6wNFA2PDJizszN NWnXbZJIW0GQR1XS
A2058 NYX3d|c3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlHNTWM2OD1yLkCwNFU1PCEQvF2= MnfLV2FPT0WU
ETK-1 MlzMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVzJR|UxRTBwMECwOVU5KM7:TR?= Ml3qV2FPT0WU
NEC8 NUPNV3F6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEH6V4hKSzVyPUCuNFAxPTZzIN88US=> MY\TRW5ITVJ?
TE-11 NVyxXVd2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGHodllKSzVyPUCuNFAxPTZ7IN88US=> NETzNppUSU6JRWK=
NCI-H720 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3u4e2lEPTB;MD6wNFA2QCEQvF2= M372NnNCVkeHUh?=
PSN1 NUHxN5pRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M33FV2lEPTB;MD6wNFA2QDFizszN M1H4TXNCVkeHUh?=
SW780 Ml\vS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIfz[4hKSzVyPUCuNFAxPTh5IN88US=> NVfMRnVSW0GQR1XS
8-MG-BA MmfGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXG1eYx1UUN3ME2wMlAxODV6OTFOwG0> NVrVcW9jW0GQR1XS
EC-GI-10 NFTRTHlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHfDWpVKSzVyPUCuNFAxPTl{IN88US=> M3faZXNCVkeHUh?=
SJSA-1 MlfRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{fxUWlEPTB;MD6wNFA3OTVizszN NXXaWmdGW0GQR1XS
639-V MnnrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVjSPVhXUUN3ME2wMlAxODZ2NzFOwG0> M1vJTnNCVkeHUh?=
PFSK-1 NX7tWIh7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkfFTWM2OD1yLkCwNFY2PyEQvF2= MmTaV2FPT0WU
DMS-273 NVPsU2o5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHqyRnlKSzVyPUCuNFAxPjd2IN88US=> NIjPb4FUSU6JRWK=
TE-9 Mm\RS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{L6TGlEPTB;MD6wNFA3PzZizszN Mmm4V2FPT0WU
SCC-25 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MorGTWM2OD1yLkCwNFY5KM7:TR?= NFHKe4tUSU6JRWK=
PA-1 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlzNTWM2OD1yLkCwNFY5PyEQvF2= NYXlSIJnW0GQR1XS
MHH-ES-1 NFLpZ5RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXHQPXh2UUN3ME2wMlAxODdizszN MkTXV2FPT0WU
Daoy MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEfnclFKSzVyPUCuNFAxPyEQvF2= M3jFZXNCVkeHUh?=
G-402 NIrqR2xIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml;WTWM2OD1yLkCwNFcxPiEQvF2= NEW0bZRUSU6JRWK=
YKG-1 M17zc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnrtTWM2OD1yLkCwNFcxPyEQvF2= NV\FNGFrW0GQR1XS
Ca-Ski NEHuZWxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXTQeWlLUUN3ME2wMlAxODd{ODFOwG0> NGq2UlNUSU6JRWK=
CHP-212 NIO3Om1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{[0R2lEPTB;MD6wNFA4OyEQvF2= NYDQTlV{W0GQR1XS
SCC-4 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlXJTWM2OD1yLkCwNFc{QSEQvF2= NH;CcXFUSU6JRWK=
EW-3 M3\pZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn3vTWM2OD1yLkCwNFc1PSEQvF2= MnewV2FPT0WU
P12-ICHIKAWA NVryfWtxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIniZVVKSzVyPUCuNFAxPzR3IN88US=> Mni5V2FPT0WU
HSC-2 Ml\ES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH;keHZKSzVyPUCuNFAxPzV3IN88US=> MoPBV2FPT0WU
HN M4XPcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlmwTWM2OD1yLkCwNFc2QCEQvF2= NXX0e4FuW0GQR1XS
LXF-289 MmDYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MojwTWM2OD1yLkCwNFc2QCEQvF2= MYTTRW5ITVJ?
ES1 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV3JR|UxRTBwMECwO|ch|ryP MUXTRW5ITVJ?
NTERA-S-cl-D1 NGW4cVlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlPnTWM2OD1yLkCwNFc4OyEQvF2= NXfjdldzW0GQR1XS
K5 NV:yWohzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{TrbmlEPTB;MD6wNFA4PzhizszN NFXnfm9USU6JRWK=
HOS M4nuSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoXSTWM2OD1yLkCwNFc5OiEQvF2= M{fZOnNCVkeHUh?=
YH-13 NXjnT|Y5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWC5c2x[UUN3ME2wMlAxODd7MTFOwG0> NUX0PY4{W0GQR1XS
SW954 NEKw[XlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2DUOmlEPTB;MD6wNFA5OjNizszN MmPOV2FPT0WU
KYSE-510 NGi0NHJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYXJR|UxRTBwMECwPFQh|ryP MVvTRW5ITVJ?
8505C M1fZeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml\ETWM2OD1yLkCwNFg2PCEQvF2= Mn2xV2FPT0WU
A549 NXfJbWt4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NET5[XlKSzVyPUCuNFAxQDh{IN88US=> M3[5PXNCVkeHUh?=
Detroit562 NYL5b|NvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1jXZWlEPTB;MD6wNFA6ODJizszN NI\kRnJUSU6JRWK=
ES5 M2C4SWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M17ad2lEPTB;MD6wNFA6OSEQvF2= MlqzV2FPT0WU
KYSE-140 MnrKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4XRc2lEPTB;MD6wNFA6OzNizszN M4[5XnNCVkeHUh?=
GMS-10 Mn7WS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnHkTWM2OD1yLkCwNFk1OSEQvF2= NXn3UopHW0GQR1XS
D-263MG NYGxPYk4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3nONmlEPTB;MD6wNFA6PDdizszN NUe0R45nW0GQR1XS
BCPAP MlfnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYjJR|UxRTBwMECwPVQ4KM7:TR?= NWroXHlYW0GQR1XS
CHL-1 NFXjb3RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3jieWlEPTB;MD6wNFA6PThizszN M2TpWnNCVkeHUh?=
RKO NV\4dpFFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXr4dHZ4UUN3ME2wMlAxODl6OTFOwG0> NHm5TmpUSU6JRWK=
SW48 NGDhcJJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYHocHJ7UUN3ME2wMlAxOTBzIN88US=> NYLGPFNSW0GQR1XS
BPH-1 NFnhUppIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnHETWM2OD1yLkCwNVAzKM7:TR?= MXXTRW5ITVJ?
EFO-27 NGrR[XdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NInMWZBKSzVyPUCuNFAyODJizszN MWrTRW5ITVJ?
CAL-33 NV20TGhNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUDJR|UxRTBwMECxNFQh|ryP NGq5SZFUSU6JRWK=
NCI-H1792 M{DoXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3PXZWlEPTB;MD6wNFExPCEQvF2= MlH6V2FPT0WU
BB30-HNC MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3j0fGlEPTB;MD6wNFExPSEQvF2= MX7TRW5ITVJ?
VM-CUB-1 NEjPcWJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXXUV4lQUUN3ME2wMlAxOTB3IN88US=> MmfDV2FPT0WU
TE-5 M4DUW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVvJR|UxRTBwMECxNFYh|ryP Mm\VV2FPT0WU
NB13 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkHaTWM2OD1yLkCwNVA4KM7:TR?= NGjvUZZUSU6JRWK=
NBsusSR NYT1O5B1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF\nWZJKSzVyPUCuNFAyOSEQvF2= NED2[WlUSU6JRWK=
LNCaP-Clone-FGC MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWfJR|UxRTBwMECxNUDPxE1? NYnyco8xW0GQR1XS
EPLC-272H NXLEcmJkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFvRcZVKSzVyPUCuNFAyOTFizszN MXjTRW5ITVJ?
KNS-62 M1zuR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4nwZWlEPTB;MD6wNFEyOiEQvF2= MX;TRW5ITVJ?
RERF-LC-MS MkO0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NW\oR5o4UUN3ME2wMlAxOTF|IN88US=> MUjTRW5ITVJ?
LOXIMVI MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{C5b2lEPTB;MD6wNFEyPiEQvF2= MkK3V2FPT0WU
KINGS-1 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnfHTWM2OD1yLkCwNVE4KM7:TR?= MlX6V2FPT0WU
T98G M4fsPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mm\MTWM2OD1yLkCwNVE4KM7:TR?= MVnTRW5ITVJ?
HCC1806 NULGWJZ1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmnLTWM2OD1yLkCwNVE5KM7:TR?= NGniZm1USU6JRWK=
MZ1-PC M2DqbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFfZfGlKSzVyPUCuNFAyOThizszN NV;yd3p5W0GQR1XS
RT-112 NHXpXnFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHLOVJRKSzVyPUCuNFAyOTlizszN MUfTRW5ITVJ?
LK-2 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml\kTWM2OD1yLkCwNVIyKM7:TR?= MlLHV2FPT0WU
A375 NU\VS29kT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{jE[WlEPTB;MD6wNFEzOSEQvF2= NFexUpVUSU6JRWK=
SF268 MmjnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFuxNWlKSzVyPUCuNFAyOjFizszN MkSyV2FPT0WU
H9 MnyyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NETTR|NKSzVyPUCuNFAyOjRizszN MlvWV2FPT0WU
KYSE-410 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEHne4RKSzVyPUCuNFAyOjRizszN M2rPb3NCVkeHUh?=
G-401 MkjkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUnHc41XUUN3ME2wMlAxOTJ5IN88US=> NYCzcnpiW0GQR1XS
SW982 NYrUNXpUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1PxeGlEPTB;MD6wNFEzPyEQvF2= MoS5V2FPT0WU
D-423MG M2jMTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWfJR|UxRTBwMECxN{DPxE1? Mlu0V2FPT0WU
CAMA-1 MlX3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH71eolKSzVyPUCuNFAyOzFizszN NWrpdm9EW0GQR1XS
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CaR-1 NHP6XWpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmfJTWM2OD1yLkCwN|I4KM7:TR?= MY\TRW5ITVJ?
AGS NIP4dItIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXXJR|UxRTBwMECzNlgh|ryP NHLtNldUSU6JRWK=
SF126 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFfINZZKSzVyPUCuNFA{OjlizszN NH60WYFUSU6JRWK=
UACC-62 MlzzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3K4WGlEPTB;MD6wNFM{KM7:TR?= MnfmV2FPT0WU
NCI-H28 MkjRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHPubXpKSzVyPUCuNFA{OzRizszN M4nHdHNCVkeHUh?=
A2780 NYP6PIVpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVHJR|UxRTBwMECzN|Uh|ryP M3W2cnNCVkeHUh?=
CTV-1 NIXKd2hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mki0TWM2OD1yLkCwN|M4KM7:TR?= M2TtSnNCVkeHUh?=
LC-2-ad M4W2WGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXm0OHN[UUN3ME2wMlAxOzRizszN NF7kS2hUSU6JRWK=
NCI-H1770 Mn3OS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF;RPHJKSzVyPUCuNFA{PDJizszN M4SxfHNCVkeHUh?=
HuO9 NHPwbIlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYTTeGpLUUN3ME2wMlAxOzR4IN88US=> M3vF[nNCVkeHUh?=
U-266 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEP4fI1KSzVyPUCuNFA{PDhizszN NIn2NWxUSU6JRWK=
MLMA MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXPJR|UxRTBwMECzOVUh|ryP NX;mPWJVW0GQR1XS
U-87-MG NFnsd45Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlXjTWM2OD1yLkCwN|U2KM7:TR?= NXnzbIxqW0GQR1XS
GI-ME-N Ml7aS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmTQTWM2OD1yLkCwN|U5KM7:TR?= MYLTRW5ITVJ?
HL-60 NEX0NGJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWrJR|UxRTBwMECzOVkh|ryP NFf5TpBUSU6JRWK=
EGI-1 Mk\YS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4jqXmlEPTB;MD6wNFM3OiEQvF2= NX71WGl7W0GQR1XS
NCI-H23 NEnaOItIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGmzO3hKSzVyPUCuNFA{PjRizszN NI[xNI9USU6JRWK=
NCI-H226 NUPtWppGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH\Rb|hKSzVyPUCuNFA{PjhizszN NETkdnZUSU6JRWK=
NCI-H520 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1THb2lEPTB;MD6wNFM4OiEQvF2= NIDpepVUSU6JRWK=
L-363 M{fWfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWXvOWdOUUN3ME2wMlAxOzd4IN88US=> NIHad5JUSU6JRWK=
CAL-12T MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXLIbmZ1UUN3ME2wMlAxOzd4IN88US=> NEj5NZJUSU6JRWK=
BT-20 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYDvdlFHUUN3ME2wMlAxOzd4IN88US=> MXPTRW5ITVJ?
SNB75 MnmzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlX3TWM2OD1yLkCwN|gyKM7:TR?= M4LN[HNCVkeHUh?=
A4-Fuk MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MorRTWM2OD1yLkCwN|kh|ryP NVmxWnF[W0GQR1XS
BE-13 MkjLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGX1[|RKSzVyPUCuNFA{QTNizszN MXfTRW5ITVJ?
NCI-H1395 NIHUV|BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVXySox[UUN3ME2wMlAxOzl4IN88US=> MVfTRW5ITVJ?
SW620 M4HpVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NW\Fd4Q4UUN3ME2wMlAxOzl5IN88US=> MYfTRW5ITVJ?
KNS-81-FD MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M17rO2lEPTB;MD6wNFM6QSEQvF2= NXuzWYMxW0GQR1XS
RD MonYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWHJR|UxRTBwMEC0JO69VQ>? NFP3b2FUSU6JRWK=
HLE NW\vbmhPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF3aUWVKSzVyPUCuNFA1ODVizszN MmWyV2FPT0WU
OVCAR-3 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnXxTWM2OD1yLkCwOFA4KM7:TR?= MWrTRW5ITVJ?
KM12 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml3oTWM2OD1yLkCwOFA5KM7:TR?= MnT2V2FPT0WU
HCC2998 M3T0[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWjTOpduUUN3ME2wMlAxPDB6IN88US=> MVrTRW5ITVJ?
D-502MG NVP6Zm9oT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NI\MOGhKSzVyPUCuNFA1OSEQvF2= MkfRV2FPT0WU
KNS-42 NEX3SGdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGD0cHFKSzVyPUCuNFA1OTJizszN MmjPV2FPT0WU
LS-123 MmTNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIjveoxKSzVyPUCuNFA1OjVizszN MUTTRW5ITVJ?
SiHa NHf2V2ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYLreGxLUUN3ME2wMlAxPDNizszN M4X5RnNCVkeHUh?=
T47D M2nzXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1\FZ2lEPTB;MD6wNFQ{OSEQvF2= Mn3kV2FPT0WU
EW-24 MmOyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1Pue2lEPTB;MD6wNFQ{OyEQvF2= NEDYSYxUSU6JRWK=
CAL-120 NGDie3JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYP3UGxWUUN3ME2wMlAxPDN3IN88US=> MkX4V2FPT0WU
JAR MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnSyTWM2OD1yLkCwOFM4KM7:TR?= NX3Re2o1W0GQR1XS
QIMR-WIL M{nSOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXzJR|UxRTBwMEC0N|gh|ryP NFr3OYRUSU6JRWK=
OCUB-M M3LlNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVHwU4R5UUN3ME2wMlAxPDN6IN88US=> MkmxV2FPT0WU
Calu-6 NGDwUYVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWDJR|UxRTBwMEC0OFch|ryP MkLVV2FPT0WU
MDA-MB-453 NVrVRZRtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGPoWZBKSzVyPUCuNFA1PTFizszN M17EcHNCVkeHUh?=
MKN45 NWTjb|ZZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{HETmlEPTB;MD6wNFQ2OyEQvF2= NHLxcIZUSU6JRWK=
ECC10 NFPxT5pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmDXTWM2OD1yLkCwOFYh|ryP M1jyUnNCVkeHUh?=
RVH-421 NEPDXJJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnfuTWM2OD1yLkCwOFYyKM7:TR?= M1\5O3NCVkeHUh?=
TGBC11TKB M13CUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoD0TWM2OD1yLkCwOFY6KM7:TR?= M2W5dXNCVkeHUh?=
MOLT-4 NFf0d29Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH;mTVhKSzVyPUCuNFA1PzFizszN M3j5cnNCVkeHUh?=
LN-405 MlvUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXvJR|UxRTBwMEC0PFIh|ryP NGK4fXRUSU6JRWK=
S-117 Ml6zS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUTJR|UxRTBwMEC0PFYh|ryP MofEV2FPT0WU
RPMI-8226 M3;nN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmDUTWM2OD1yLkCwOFk4KM7:TR?= MUXTRW5ITVJ?
KYSE-150 M2\aXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUH3cVdGUUN3ME2wMlAxPDl7IN88US=> NYOzSpo2W0GQR1XS
NCI-H1666 NI\zXm5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXTJR|UxRTBwMEC1NFUh|ryP NWL3WFRJW0GQR1XS
Mewo NHv2UXFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXfJR|UxRTBwMEC1NFUh|ryP NX22XWNsW0GQR1XS
AN3-CA M3WzUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4HSTGlEPTB;MD6wNFUxPyEQvF2= MV\TRW5ITVJ?
COLO-680N NVfwRWJVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn7mTWM2OD1yLkCwOVA5KM7:TR?= M4DWVXNCVkeHUh?=
FADU NFP4XlNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXy0OlhDUUN3ME2wMlAxPTFizszN MVPTRW5ITVJ?
GB-1 Mo\OS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MU\JR|UxRTBwMEC1NVEh|ryP Ml;OV2FPT0WU
KASUMI-1 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NU\pSpA3UUN3ME2wMlAxPTFzIN88US=> NWTzUWo5W0GQR1XS
NOMO-1 NWf2UVRpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkLnTWM2OD1yLkCwOVE{KM7:TR?= NX\vU4FmW0GQR1XS
BV-173 NGS3cIJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHHNSVdKSzVyPUCuNFA2OyEQvF2= NEHzU5lUSU6JRWK=
RO82-W-1 NHrNWYRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWTjXXVvUUN3ME2wMlAxPTNzIN88US=> NI\0eIpUSU6JRWK=
LB2241-RCC MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV;DW40yUUN3ME2wMlAxPTNzIN88US=> M3q3OHNCVkeHUh?=
NCI-H2170 NUTzUWh6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MorjTWM2OD1yLkCwOVM2KM7:TR?= NIjPNVJUSU6JRWK=
SK-N-AS NF3aV4lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmXPTWM2OD1yLkCwOVM2KM7:TR?= M4DzXXNCVkeHUh?=
NCI-H1651 NFHQSFJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVLJR|UxRTBwMEC1OEDPxE1? NX;temhOW0GQR1XS
NCI-SNU-5 NIjpZVlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYfJR|UxRTBwMEC1OFUh|ryP Mle4V2FPT0WU
SN12C NXe0enJQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{\BSGlEPTB;MD6wNFU2KM7:TR?= M2f1[XNCVkeHUh?=
KY821 M1nze2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmfkTWM2OD1yLkCwOVUyKM7:TR?= NVX0SoZ{W0GQR1XS
SW1573 NEnBbodIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYHJR|UxRTBwMEC1OVQh|ryP MXnTRW5ITVJ?
OE19 M2\P[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoX3TWM2OD1yLkCwOVU6KM7:TR?= NVPRSGZPW0GQR1XS
MPP-89 MljUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MojJTWM2OD1yLkCwOVY4KM7:TR?= MUnTRW5ITVJ?
HuCCT1 NHPUbZVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NULUSGo1UUN3ME2wMlAxPTZ6IN88US=> NH\JdZBUSU6JRWK=
SW1783 M4\6bWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NILHVnFKSzVyPUCuNFA2PyEQvF2= NXT1NHY2W0GQR1XS
8305C NVfYW2ZbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGTCWWNKSzVyPUCuNFA2PzZizszN M{DTR3NCVkeHUh?=
OVCAR-4 M3L5dGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVPJR|UxRTBwMEC1PFYh|ryP MVzTRW5ITVJ?
MMAC-SF NXLSN2ZHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MljQTWM2OD1yLkCwOVg3KM7:TR?= NXvNR|U2W0GQR1XS
COLO-824 NGfF[XBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUPJR|UxRTBwMEC1PUDPxE1? M4Xjd3NCVkeHUh?=
HCC38 MlLaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWHJR|UxRTBwMEC2JO69VQ>? MnS2V2FPT0WU
NCI-H1648 MnXTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2\3N2lEPTB;MD6wNFYxOSEQvF2= MVzTRW5ITVJ?
NCI-H1573 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M17Qd2lEPTB;MD6wNFYxPyEQvF2= NWDNdFRxW0GQR1XS
MFM-223 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXTJR|UxRTBwMEC2NVYh|ryP MkHXV2FPT0WU
NCI-H810 MmjBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnHjTWM2OD1yLkCwOlIzKM7:TR?= NVLoPFN2W0GQR1XS
EM-2 NHv1XZdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{\PSGlEPTB;MD6wNFYzOyEQvF2= Mn3tV2FPT0WU
D-283MED MoLMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NETEZ2pKSzVyPUCuNFA3OjRizszN NID5PJhUSU6JRWK=
NCI-H1755 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYXJc3BWUUN3ME2wMlAxPjJ2IN88US=> NXPzZmpUW0GQR1XS
KYSE-70 NHq3VYFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFnaeYJKSzVyPUCuNFA3OjRizszN M37wNXNCVkeHUh?=
SW626 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1H1[WlEPTB;MD6wNFYzPCEQvF2= NH7aUoRUSU6JRWK=
WM-115 NV3rVHVyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHzYdVhKSzVyPUCuNFA3OjdizszN NILXXZVUSU6JRWK=
NB69 NVzhNWNHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYjJR|UxRTBwMEC2Nlkh|ryP M3vKbnNCVkeHUh?=
DOHH-2 MoTQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV;JR|UxRTBwMEC2N{DPxE1? NULVT3NHW0GQR1XS
MEL-JUSO NYTodWF{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVWxRWNNUUN3ME2wMlAxPjN7IN88US=> MonVV2FPT0WU
IGR-1 M1LudGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHLyb3BKSzVyPUCuNFA3PDFizszN MVzTRW5ITVJ?
ACN M2nNWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mm[0TWM2OD1yLkCwOlQ1KM7:TR?= MYnTRW5ITVJ?
KARPAS-45 Mne2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnnXTWM2OD1yLkCwOlUzKM7:TR?= NIHnSY9USU6JRWK=
HC-1 Ml3WS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkjYTWM2OD1yLkCwOlU3KM7:TR?= MXzTRW5ITVJ?
MZ2-MEL NHHZWVBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWX6d3R{UUN3ME2wMlAxPjV6IN88US=> NY[1Nlk{W0GQR1XS
NCI-H1355 M3T2cGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkLzTWM2OD1yLkCwOlc6KM7:TR?= MnTyV2FPT0WU
HuP-T4 NUXqOnJmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmrsTWM2OD1yLkCwOlc6KM7:TR?= NFWyPFFUSU6JRWK=
AsPC-1 NV3ae2pYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3P3eWlEPTB;MD6wNFY5OyEQvF2= NH\oNHpUSU6JRWK=
SCC-15 M1vnemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGfH[nJKSzVyPUCuNFA3QDlizszN NEKwVGVUSU6JRWK=
CP50-MEL-B M1zLPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3fsPGlEPTB;MD6wNFY6OyEQvF2= M4XKZXNCVkeHUh?=
DMS-114 NV;XWXpzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlnuTWM2OD1yLkCwOlk3KM7:TR?= Mn\OV2FPT0WU
KYSE-520 NF;rRo9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFK0T2dKSzVyPUCuNFA4KM7:TR?= NH\yVYFUSU6JRWK=
NCI-H2228 NVzZSGtzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoHsTWM2OD1yLkCwO|I2KM7:TR?= M{DuSHNCVkeHUh?=
COLO-829 MmO0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYX2dYtVUUN3ME2wMlAxPzJ3IN88US=> NVTJWVNOW0GQR1XS
NCI-H2052 M2P5WWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkLxTWM2OD1yLkCwO|I4KM7:TR?= M2D0RnNCVkeHUh?=
HOP-92 NYn0PGNGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmiyTWM2OD1yLkCwO|Mh|ryP NYD5Umh4W0GQR1XS
MDA-MB-231 MlT5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{XwSmlEPTB;MD6wNFc{KM7:TR?= MkPXV2FPT0WU
SK-MEL-30 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MonQTWM2OD1yLkCwO|MzKM7:TR?= M2\aTnNCVkeHUh?=
NCI-H2087 M1;aN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXv3[HF1UUN3ME2wMlAxPzR6IN88US=> Ml36V2FPT0WU
SW900 MnzTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXXJR|UxRTBwMEC3OVUh|ryP MnLwV2FPT0WU
NCI-H358 Mo\rS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV\rVoFPUUN3ME2wMlAxPzV6IN88US=> M3vNe3NCVkeHUh?=
NCI-H2126 NITVNWNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWLJR|UxRTBwMEC3O|Mh|ryP MUfTRW5ITVJ?
TGBC24TKB MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmPmTWM2OD1yLkCwO|gyKM7:TR?= NW\me4Z3W0GQR1XS
786-0 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{D1cmlEPTB;MD6wNFc5PiEQvF2= NGrrVGNUSU6JRWK=
no-10 M3HJPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2TRUmlEPTB;MD6wNFc5QCEQvF2= NGXQbXRUSU6JRWK=
SCH M2nHOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MULJR|UxRTBwMEC4NVgh|ryP MluxV2FPT0WU
COLO-741 NVXIdotzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVLJR|UxRTBwMEC4NkDPxE1? MkLnV2FPT0WU
NCI-H82 M2rZWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYrJR|UxRTBwMEC4NlIh|ryP MlfWV2FPT0WU
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HT NG\NW21Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4\mZmlEPTB;MD6wOFAxPyEQvF2= NHX0SFdUSU6JRWK=
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NCI-H1693 NH7EOndIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFvDUZlKSzVyPUCuNFQ{ODVizszN M3HWZnNCVkeHUh?=
LAN-6 NI\6XIRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mm\XTWM2OD1yLkC0N|M2KM7:TR?= MlezV2FPT0WU
MDA-MB-175-VII NWjPcGpMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV\x[nVYUUN3ME2wMlA1PDF5IN88US=> NFPF[YZUSU6JRWK=
KMOE-2 NIXROplIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1Pk[2lEPTB;MD6wOFQ3QSEQvF2= NIexcGRUSU6JRWK=
DMS-79 MlLDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYrOXlJnUUN3ME2wMlA1PTd7IN88US=> NEPWNo1USU6JRWK=
MHH-NB-11 M{HleGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYDGS3RjUUN3ME2wMlA1PjF2IN88US=> M{e5T3NCVkeHUh?=
NCI-H69 NYfPWo9yT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFLCTGlKSzVyPUCuNFQ5PDlizszN M1TYNHNCVkeHUh?=
KE-37 M3nPUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{T6bWlEPTB;MD6wOVAyKM7:TR?= NYXXOZdyW0GQR1XS
Ramos-2G6-4C10 NVrDU2FTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmP0TWM2OD1yLkC1NFY4KM7:TR?= NF\M[GxUSU6JRWK=
NCI-H1793 M2rWXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3jQcGlEPTB;MD6wOVA6OyEQvF2= M3jjSHNCVkeHUh?=
HT-1376 Mom3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFX1WXVKSzVyPUCuNFUyQDZizszN MYnTRW5ITVJ?
EKVX NEfPfYpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mm\NTWM2OD1yLkC1N|g1KM7:TR?= M4PZWXNCVkeHUh?=
Capan-2 MmLLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIPEdG5KSzVyPUCuNFU{QTZizszN Mn3aV2FPT0WU
DoTc2-4510 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWfJR|UxRTBwMEW0OFYh|ryP M1PRdHNCVkeHUh?=
UACC-893 NFX5dJdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXHJR|UxRTBwMEW0OlIh|ryP NGHaOmxUSU6JRWK=
SK-MEL-3 NVGz[XRiT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWXJR|UxRTBwMEW3PFgh|ryP NX;veJp1W0GQR1XS
SK-MEL-1 M{i5VWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1vkTmlEPTB;MD6wOVgh|ryP MXLTRW5ITVJ?
SW948 M3XHPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXe5VnV{UUN3ME2wMlA2QTl4IN88US=> M131ZXNCVkeHUh?=
P30-OHK MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEjC[|JKSzVyPUCuNFYyPjdizszN MkfLV2FPT0WU
NH-12 NWTxWGN2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFKySpRKSzVyPUCuNFYzPDRizszN NIXqTIpUSU6JRWK=
KU-19-19 M1LiTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXi1b25PUUN3ME2wMlA3OzZzIN88US=> MlzsV2FPT0WU
A431 M1jOeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX7JR|UxRTBwME[zO|Qh|ryP NHrwSW1USU6JRWK=
NCI-H2405 MkLvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUTJR|UxRTBwME[zPFMh|ryP Mn\zV2FPT0WU
KARPAS-299 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGTuXW5KSzVyPUCuNFY2QDJizszN NX7SW29kW0GQR1XS
BALL-1 M2jUdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV\pfplqUUN3ME2wMlA3Pjd2IN88US=> MWrTRW5ITVJ?
KURAMOCHI NEnCZnNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXGwPGVEUUN3ME2wMlA4ODd|IN88US=> NXHrVVFEW0GQR1XS
LS-1034 NUn3WW1GT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4HzSGlEPTB;MD6wO|M3QSEQvF2= M37WSXNCVkeHUh?=
MFE-280 NXPEWpNJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MULJR|UxRTBwMEe1N|Yh|ryP NVfBW5lCW0GQR1XS
HOP-62 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFz6UW5KSzVyPUCuNFc3PzZizszN NIDoUnJUSU6JRWK=
KG-1 NUK5d5E2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVvJR|UxRTBwMEe3PFch|ryP M2PnWHNCVkeHUh?=
CW-2 Mnq4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mo\2TWM2OD1yLkC3PFMzKM7:TR?= NUjtdo55W0GQR1XS
SW837 MmDYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MULJR|UxRTBwMEizOFIh|ryP MVvTRW5ITVJ?
MFH-ino M1\lNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUDJR|UxRTBwMEi1NFEh|ryP MmnMV2FPT0WU
HCC1419 NXO3PZBqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVTJR|UxRTBwMEi5PFch|ryP NE\DTJNUSU6JRWK=
HMV-II M{fZUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEe2OoNKSzVyPUCuNFkxOSEQvF2= NXniVYVFW0GQR1XS
BEN NGLXWG5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn7ZTWM2OD1yLkC5N|g2KM7:TR?= NXnTV3h3W0GQR1XS
SK-N-FI MoHQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVzzZmZYUUN3ME2wMlA6PTV4IN88US=> M{HBO3NCVkeHUh?=
JVM-2 MojvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWLTZnVRUUN3ME2wMlA6PzF4IN88US=> M17XZXNCVkeHUh?=
CAL-54 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MU\JR|UxRTBwMUCwOEDPxE1? MkPQV2FPT0WU
T84 Ml63S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYr5SYkyUUN3ME2wMlExQTV{IN88US=> MWPTRW5ITVJ?
SHP-77 NFO5d5ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2SydGlEPTB;MD6xNVY1OSEQvF2= NGrvd4VUSU6JRWK=
G-361 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXPuNIlGUUN3ME2wMlEzOzJ2IN88US=> NVPSb5I6W0GQR1XS
Calu-3 NGXnd21Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWjJR|UxRTBwMUO4NVYh|ryP MnztV2FPT0WU
HCC1937 NFHtZo9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkeyTWM2OD1yLkG0PVM4KM7:TR?= M2HFW3NCVkeHUh?=
KM-H2 MnzaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXrJR|UxRTBwMUWwNUDPxE1? NUTMco5LW0GQR1XS
769-P NFTWVFBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnzITWM2OD1yLkG1PFQ{KM7:TR?= M4OzcXNCVkeHUh?=
NCI-H1304 NWXSTWRKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{fiSGlEPTB;MD6xOlA3OSEQvF2= M4HZU3NCVkeHUh?=
D-542MG MmLLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3nOSmlEPTB;MD6xOlI4QCEQvF2= MnL4V2FPT0WU
ATN-1 M{L1bGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnzxTWM2OD1yLkG3OFQyKM7:TR?= MYnTRW5ITVJ?
NCI-H2029 NHHRcoNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGe0VmpKSzVyPUCuNlAzPDNizszN MWnTRW5ITVJ?
ZR-75-30 MlSxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX3JR|UxRTBwMkC2OFMh|ryP NUTVZ3RxW0GQR1XS
SW1116 M1PWeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mnr1TWM2OD1yLkKxNVE4KM7:TR?= MoXzV2FPT0WU
CCRF-CEM MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{nhT2lEPTB;MD6yO|YyPCEQvF2= MofrV2FPT0WU
LU-135 NGSyS|VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MojMTWM2OD1yLkK3O|M6KM7:TR?= NEP2O4lUSU6JRWK=
MC116 MoPaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4r6NmlEPTB;MD6yPFMxQSEQvF2= MVnTRW5ITVJ?
LS-513 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2Hld2lEPTB;MD6yPFc4OyEQvF2= NUjud2tJW0GQR1XS
NCI-H630 MmXPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWDsXHNNUUN3ME2wMlI6Ozd4IN88US=> NHnMWGxUSU6JRWK=
L-428 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHjhV4JKSzVyPUCuNlk5QDNizszN NXv6VIo6W0GQR1XS
UM-UC-3 NIjETIRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1\HTGlEPTB;MD6zNVI6OSEQvF2= M3LsSXNCVkeHUh?=
NCI-H1838 MlKxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXrxTGZ7UUN3ME2wMlMyPzh2IN88US=> NYPzS25GW0GQR1XS
HEL M4[wRmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2X5d2lEPTB;MD6zNlI1KM7:TR?= MmmxV2FPT0WU
OCI-AML2 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXzJR|UxRTBwM{KyPVgh|ryP NWnqd5ptW0GQR1XS
A3-KAW M4jjSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWXYT4dOUUN3ME2wMlM{PDd5IN88US=> MXnTRW5ITVJ?
IGROV-1 MoL0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1X6N2lEPTB;MD6zN|c2PSEQvF2= NUHzb25XW0GQR1XS
Mo-T NUXYT|ZjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoHrTWM2OD1yLkOzPFU{KM7:TR?= NGTMT5dUSU6JRWK=
HDLM-2 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV\LWWdXUUN3ME2wMlM{QSEQvF2= MUjTRW5ITVJ?
HCC1569 NHj2UoNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXXJR|UxRTBwM{SzNFkh|ryP MmnEV2FPT0WU
COLO-678 NFjMVYhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYHJWXloUUN3ME2wMlM4ODB{IN88US=> NX;kemNDW0GQR1XS
COR-L105 MnjGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIrFeG9KSzVyPUCuN|c6OyEQvF2= MX7TRW5ITVJ?
SK-MEL-24 MoHjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUT5UpA4UUN3ME2wMlM5Ozh{IN88US=> M4W2cnNCVkeHUh?=
COLO-320-HSR M1jsUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmPjTWM2OD1yLkSzPVc3KM7:TR?= M33Xc3NCVkeHUh?=
C8166 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MofKTWM2OD1yLkS5NFI{KM7:TR?= NXjJU3NnW0GQR1XS
COLO-679 Mlj3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF7rWZZKSzVyPUCuOlIyPzJizszN MkXxV2FPT0WU
TE-12 M3f1U2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1j2XmlEPTB;MD62OVM6PCEQvF2= MXjTRW5ITVJ?
HAL-01 M2KwXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF;KOHVKSzVyPUCuOlYzOiEQvF2= MlvrV2FPT0WU
H-EMC-SS NF[1PYJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEjrPINKSzVyPUCuO|A2PDZizszN MmXMV2FPT0WU
SNU-449 Mny4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFm5[|FKSzVyPUCuO|I4PDhizszN MUjTRW5ITVJ?
C32 NULtZWRYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3PDWmlEPTB;MD63OFEyOiEQvF2= M371d3NCVkeHUh?=
K-562 NGTUUlRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVLJR|UxRTBwN{ewNlQh|ryP MWLTRW5ITVJ?
DJM-1 NWf0boVbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYTvdGZGUUN3ME2wMlc5PzhzIN88US=> NWfVV3JZW0GQR1XS
RCC10RGB MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWLJR|UxRTBwN{mxPFMh|ryP NWnIWnBmW0GQR1XS
CAL-85-1 NXHmcZV4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NI\y[phKSzVyPUCuPVA4KM7:TR?= M4rqdHNCVkeHUh?=
NY M4fme2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUHLdIpIUUN3ME2wMlk{OzV{IN88US=> M3PpbHNCVkeHUh?=
NCI-H1993 M2rPc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{X4UGlEPTB;MT6xPVI5QSEQvF2= M{HjUnNCVkeHUh?=
SK-OV-3 Ml7WS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnXMTWM2OD1zLkKyNFg6KM7:TR?= NUTtZ2s1W0GQR1XS

他の多くの細胞株試験データをご覧になる場合はこちらをクリックして下さい

アッセイ
Methods Test Index PMID
Western blot
PIM1; 

PubMed: 18426800     


Cells were treated with 100 nm docetaxel for the indicated times. PIM1 and β-ACTIN proteins were analyzed by immunoblot analysis. One of three similar blots is shown. Ratio, ratio of PIM1/β-ACTIN from pooled densitometry data from three separate experimen䲧疝Ỵ疞㧀疜膉痘 瘿뾠ՂᾰƌՂĀ 㺣痖帉痖Ѐ瑖堘𢡄빢᎒ՂĀ鑸᎒彿堙奋堙巫堙᎒ﻺ᎒彿堙ﻮ᎒塚堙ﻺ᎒ꍈ堞빢᎒學堙漸堞圔堙빢᎒圞堙圭堙𢡄玚Wᾰƌ ᾰƌ戤瘯Ɖ⟸෕䐺痖暼瘿⟸෕ᾰƌ

cyclin B; 

PubMed: 18426800     


Immunoblot analysis of cyclin B1 and PIM1 expression after docetaxel 10 nm (left) or 100 nm (right) treatment at various time points.

pSTAT3 / STAT3 ; 

PubMed: 18426800     


Immunoblots of RWPE-2 cells treated with 100 nm docetaxel for the indicated time.

p-p53 / p53; 

PubMed: 22996738     


C4-2 cells were treated with 5 nM docetaxel, the whole cell lysates were collected at different time points and subjected to Western blot.

18426800 22996738
Immunofluorescence
α-tubulin; 

PubMed: 27177833     


Noscapine has no effect on gross microtubule polymerization state but noscapine pre-sensitization followed by docetaxel treatment stabilizes microtubules, hence inhibits cell proliferation. TNBC cells were treated with noscapine (4 µM) or docetaxel (0.4 µ䲧疝Ỵ疞㧀疜膉痘 瘿⟸෕ᾰƌ෕Ð 㺣痖帉痖Ѐ瑖堘𢡄빢᎒෕Ð鑸᎒彿堙奋堙巫堙᎒ﻺ᎒彿堙ﻮ᎒塚堙ﻺ᎒ꍈ堞빢᎒學堙漸堞圔堙빢᎒圞堙圭堙𢡄玚Wᾰƌ ᾰƌ戤瘯Ɖ뾠Ղ䐺痖暼瘿뾠Ղᾰƌ 뾠ՂÐ㺣痖뾠Ղ€𢡄뾤Ղ€䀷痗뾤Ղ౴뾤Ղ㵶痗뾤Ղ뺖᎒泌Itemセ᎒Count﫨呂뿔Ղ猴፲뾤Ղ፲씢痗猸፲髸莤䥷堙᎒セ᎒�堞ﻮ᎒፲露𢡄堚Ҕ齃礤v�堞ﻮ᎒猢Wセ᎒䨼Ą鹿齃殺獸W戀醙

cleaved PARP / cleaved caspase-3; 

PubMed: 21087597     


Immunofluorescence images of PC-3 cells treated with the docetaxel and EM011 schedule treatment. Cells were pretreated with docetaxel for 12 h before addition of EM011 and were fixed at 48 h post docetaxel treatment compared to treatment with EM011 (10 μM䲧疝Ỵ疞㧀疜膉痘 瘿⟸෕ᾰƌ෕Ð 㺣痖帉痖Ѐ瑖堘𢡄빢᎒෕Ð鑸᎒彿堙奋堙巫堙᎒ﻺ᎒彿堙ﻮ᎒塚堙ﻺ᎒ꍈ堞빢᎒學堙漸堞圔堙빢᎒圞堙圭堙𢡄玚Wᾰƌ ᾰƌ戤瘯Ɖ�෋䐺痖暼瘿�෋ᾰƌ �෋à

Acetylated tubulin ; 

PubMed: 18426800     


Immunofluorescence of acetylated tubulin in cells treated with DMSO, 30 nM laulimalide and 30 nM docetaxel for 2.5 h. Tubulin shown in green and DAPI in blue, and the white arrow indicates microtubule bundling. Scale bar represents 10 μm.

SQSTM1 / LAMP1; 

PubMed: 29795139     


AGS cells were treated with docetaxel (10 nM) for 12 h. After immunostaining with SQSTM1 (Alexa Fluor 488, green) and LAMP1 (Alexa Fluor 594, red), cells were examined by fluorescence microscopy (scale bar 20 μm). The colocalization of SQSTM1and LAMP1 was䲧疝Ỵ疞㧀疜膉痘 瘿�෋ᾰƌ෋à 㺣痖帉痖Ѐ

27177833 21087597 18426800 29795139
Growth inhibition assay
Cell viability ; 

PubMed: 22996738     


Docetaxel inhibits the growth of LNCaP, C4-2, DU145, and PC3 prostate cancer cells. Cells were plated in 12-well plates and treated with different concentrations of docetaxel. The cell number was counted after 24 hr. 

22996738
体内試験 Docetaxel (33 mg/kg/dose, given i.v. every 4 days for 3 injections) results in a tumor growth delay of 19.3 days in M2OL2 colon xenografts. Docetaxel also shows great antitumor activities in MX-1, SK-MEL-2, LX-1 and OVCAR-3 xenografts. Docetaxel inhibits the angiogenic response to fibroblast growth factor 2 with IC 50 of 5.4 mg/kg when injected twice weekly over a 14-day period, and angiogenesis is completely blocked in mice that receives 10 mg/kg Docetaxel. Docetaxel has selectivity for endothelial cell migration and/or microvessel formation because infiltration of inflammatory cells into the Matrigel plug is much less sensitive to inhibition by Docetaxel. [7]

お薦めの試験操作(参考用のみ)

細胞試験: [5]
- 合併
  • 細胞株: Human gastric cancer cell lines MKN-28
  • 濃度: 6 nM
  • 反応時間: 3 days
  • 実験の流れ: 2000 cells in 180 μL of medium are seeded in a 96-well plate, and 20 μL of drug solution is simultaneously added in triplicate to each well. The plate is incubated for 3 days at 37°C in a humidified atmosphere of 5% CO2. On day 3, 25 μL of MTT reagent is added to each well. After 4 h of incubation, the medium is removed by aspiration. 0.2 mL of dimethylsulphoxide (DMSO) is added to each well and thoroughly mixed by using a mechanical plate mixer to dissolve the resulting MTT-formazan crystals. Absorbance at 540 nm (OD) is measured by a reader.
    (参考用のみ)
動物試験:[6]
- 合併
  • 動物モデル: Human colon carcinomas xenografts CX-1
  • 製剤: 50 mg/mL stock solution in ethanol by adding an equal volume of polysorbate 80 and diluting with 5% dextrose in water to the final volume
  • 投薬量: 33 mg/kg
  • 投与方法: i.v. every 4 days for 3 injections
    (参考用のみ)

溶解度 (25°C)

体外 DMSO 100 mg/mL (123.78 mM)
Ethanol 53 mg/mL warmed (65.6 mM)
Water Insoluble
体内 左から(NMPから)右の順に溶剤を製品に加えます(文献ではなく、Selleckの実験によるデータ):
5% DMSO+30% PEG 300+5% Tween 80+ddH2O
混合させたのち直ちに使用することを推奨します。
2mg/mL

* 溶解度測定はSelleck技術部門によって行われており、その他文献に示されている溶解度と差異がある可能性がありますが、同一ロットの生産工程で起きる正常な現象ですからご安心ください。

化学情報

分子量 807.88
化学式

C43H53NO14

CAS No. 114977-28-5
保管
in solvent
別名 RP56976, NSC 628503
Smiles CC(=O)OC12COC1CC(O)C3(C)C2C(OC(=O)C4=CC=CC=C4)C5(O)CC(OC(=O)C(O)C(NC(=O)OC(C)(C)C)C6=CC=CC=C6)C(=C(C(O)C3=O)C5(C)C)C

便利ツール

モル濃度計算器

モル濃度計算器

求めたい質量、体積または濃度を計算してください。

質量 (mg) = 濃度 (mM) x 体積 (mL) x 分子量 (g/mol)

モル濃度計算器方程式

  • 質量
    濃度
    体積
    分子量

*貯蔵液を準備するとき、常に、オンであるとわかる製品のバッチに特有の分子量を使って、を通してラベルとMSDS/COA(製品ページで利用可能な)。

希釈計算器

希釈計算器

貯蔵液を準備するために必要な希釈率を計算してください。Selleck希釈計算器は、以下の方程式に基づきます:

開始濃度 x 開始体積 = 最終濃度 x 最終体積

希釈の計算式

この方程式は、一般に略語を使われます:C1V1 = C2V2 ( 入力 出力 )

  • C1
    V1
    C2
    V2

常に貯蔵液を準備するとき、小びんラベルとMSDS/COA(オンラインで利用できる)で見つかる製品のバッチに特有の分子量を使ってください。

連続希釈計算器方程式

  • 連続希釈剤

  • 計算結果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量計算器

分子量计算器

そのモル質量と元素組成を計算するために、合成物の化学式を入力してください:

総分子量:g/mol

チップス: 化学式は大文字と小文字の区別ができます。C10H16N2O2 c10h16n2o2

モル濃度計算器

質量 濃度 体積 分子量

臨床試験

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04113005 Not yet recruiting Drug: Desmopressin Castrate Resistance Prostate Cancer Sunnybrook Health Sciences Centre|Sunnybrook Research Institute October 1 2019 Early Phase 1
NCT03700099 Recruiting Drug: Docetaxel|Drug: Enzalutamide Prostate Cancer|Castration-resistant Prostate Cancer Instituto do Cancer do Estado de São Paulo|Astellas Pharma Inc September 3 2019 Phase 2
NCT04067713 Recruiting -- Metastatic Prostate Cancer University College London|Epic Sciences September 20 2019 --
NCT03976375 Recruiting Biological: Pembrolizumab|Drug: Lenvatinib|Drug: Docetaxel Metastatic Non-Small Cell Lung Cancer Merck Sharp & Dohme Corp.|Eisai Inc. June 26 2019 Phase 3

技術サポート

ストックの作り方、阻害剤の保管方法、細胞実験や動物実験の際に注意すべき点など、製品を取扱う時に問い合わせが多かった質問に対しては取扱説明書でお答えしています。

Handling Instructions

他に質問がある場合は、お気軽にお問い合わせください。

  • * 必須

Microtubule Associatedシグナル伝達経路

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細胞株 試験類型 濃度 培養時間 溶剤類型 活性叙述 PMID