Glembatumumab vedotin

Glembatumumab vedotin (CDX-011 (DOX), CR011,CR011-vcMMAE) is an antibody-drug conjugate (ADC) composed of an fully human IgG2 monoclonal antibody (CR011) directed against glycoprotein NMB (GPNMB), conjugated to Monomethyl Auristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Glembatumumab vedotin has the potential for use in research of Breast cancer (TNBC) and advanced or metastatic melanoma.

CAS No. 1182215-65-1

サイズ	価格(税別)	在庫状況
1mg	JPY 145500	国内在庫あり
1mg*5	JPY 445500	お問い合わせ

代表番号: 045-509-1970\|電子メール：[email protected] よく尋ねられる質問

クリックしてGlembatumumab vedotinの関連製品を購入する

質量管理及び製品安全説明書

現在のバッチを見る：純度： 99% タンパク質濃度：内毒素：＜1EU/mg

99

生物活性

製品説明	Glembatumumab vedotin (CDX-011 (DOX), CR011,CR011-vcMMAE) is an antibody-drug conjugate (ADC) composed of an fully human IgG2 monoclonal antibody (CR011) directed against glycoprotein NMB (GPNMB), conjugated to Monomethyl Auristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Glembatumumab vedotin has the potential for use in research of Breast cancer (TNBC) and advanced or metastatic melanoma.

製品説明

Glembatumumab vedotin (CDX-011 (DOX), CR011,CR011-vcMMAE) is an antibody-drug conjugate (ADC) composed of an fully human IgG2 monoclonal antibody (CR011) directed against glycoprotein NMB (GPNMB), conjugated to Monomethyl Auristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Glembatumumab vedotin has the potential for use in research of Breast cancer (TNBC) and advanced or metastatic melanoma.

参考
[1] Ott PA, et al. Cancer. 2019 Apr 1;125(7):1113-1123. [2] Keir CH, et al. Expert Opin Biol Ther. 2012 Feb;12(2):259-63.

参考

製品説明

CAS No.	1182215-65-1
Formulation	1xPBS
ADC antiody	Glembatumumab
ADC cytotoxin	MMAE
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.
Shipping	Shipped under low temperature conditions

Glembatumumab vedotin

クリックしてGlembatumumab vedotinの関連製品を購入する

質量管理及び製品安全説明書

生物活性

製品説明

技術サポート