サブスタンスP

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S1189 Aprepitant <1 mg/mL 107 mg/mL 15 mg/mL
S4654 Netupitant <1 mg/mL 2 mg/mL 100 mg/mL

Substance P製品

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S1189

Aprepitant

Aprepitant is a potent and selective neurokinin-1 receptor antagonist with IC50 of 0.1 nM.

S5476

Rolapitant

Rolapitant is a selective and competitive antagonist of human substance P/NK1 receptors with antiemetic activity. It has a high affinity for the human NK1 receptor of 0.66 nM and high selectivity over the human NK2 and NK3 subtypes of >1000-fold, as well as preferential affinity for human, guinea pig, gerbil and monkey NK1 receptors over rat, mouse and rabbit.

S4654

Netupitant

Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S1189

Aprepitant

Aprepitant is a potent and selective neurokinin-1 receptor antagonist with IC50 of 0.1 nM.

2019, 103(3):432-444

2019, 8(2):97-108

2019, 10.1093/humrep/dey392

S5476

Rolapitant

Rolapitant is a selective and competitive antagonist of human substance P/NK1 receptors with antiemetic activity. It has a high affinity for the human NK1 receptor of 0.66 nM and high selectivity over the human NK2 and NK3 subtypes of >1000-fold, as well as preferential affinity for human, guinea pig, gerbil and monkey NK1 receptors over rat, mouse and rabbit.

S4654

Netupitant

Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity.

2019, 10(1):17