ErbB3 阻害剤

製品コード 製品名 製品説明 Selective / Pan IC50 / Ki
S2192 AZD8931 (Sapitinib) AZD8931 (Sapitinib) is a reversible, ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 with IC50 of 4 nM, 3 nM and 4 nM in cell-free assays, more potent than Gefitinib or Lapatinib against NSCLC cell, 100-fold more selective f Pan ErbB3, IC50: 4 nM
Tags: ErbB3 inhibitor | ErbB3 cancer | ErbB3 activity | ErbB3 phosphorylation | ErbB3 mutation