ホームページ Cytoskeletal Signaling -Cell Cycle Kinesin Kinesin-12 選択性 阻害剤

Kinesin-12 選択性 阻害剤

製品コード 製品名 製品説明 Selective / Pan IC50 / Ki
S6953 GW406108X GW406108X (GW108X) is an inhibitor of Kif15 (Kinesin-12) with an IC50 of 0.82 μM in the ATPase assay. GW406108X inhibits recombinant ULK1 kinase activity with a pIC50 of 6.37 and blocks autophagy in cells, without affecting the upstream signalling kinases mTORC1 and AMPK. Selective Kif15, IC50: 0.82 μM