mGluR2 作動薬

製品コード 製品名 製品説明 Selective / Pan IC50 / Ki
S6001 LY404039

LY404039 is a potent agonist of recombinant human mGlu2/mGlu3 receptors with Ki of 149 nM/92 nM, shows >100-fold selectivity over ionotropic glutamate receptors, glutamate transporters, and other receptors. Phase 3.

Pan Rat neurons expressing native mGlu2/3, Ki: 88 nM; Recombinant human mGlu2, Ki: 149 nM