TET

TET製品

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  • TET阻害剤 (1)
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S6682 Bobcat339 hydrochloride Bobcat339 is a selective cytosine-based TET enzyme inhibitor with IC50 of 33 μM and 73 μM for TET1 and TET2, respectively. Bobcat339 can reduce DNA 5-hydroxymethylcytosine abundance by inhibiting TET enzyme function in living cells and provide support for its utility as a viable pharmacological probe.
EMBO Mol Med, 2025, 17(10):2809-2826
Nat Cell Biol, 2024, 10.1038/s41556-024-01475-y
Cell Death Dis, 2024, 15(8):617
S6682 Bobcat339 hydrochloride Bobcat339 is a selective cytosine-based TET enzyme inhibitor with IC50 of 33 μM and 73 μM for TET1 and TET2, respectively. Bobcat339 can reduce DNA 5-hydroxymethylcytosine abundance by inhibiting TET enzyme function in living cells and provide support for its utility as a viable pharmacological probe.
EMBO Mol Med, 2025, 17(10):2809-2826
Nat Cell Biol, 2024, 10.1038/s41556-024-01475-y
Cell Death Dis, 2024, 15(8):617