VDAC

VDAC製品

All (5)
VDAC阻害剤 (4)
VDACモジュレータ(1)
新製品

製品コード	製品名称	製品説明	文献中Selleckの製品使用例
S7242	Erastin	Erastin is a ferroptosis activator by acting on mitochondrial VDAC, exhibiting selectivity for tumor cells bearing oncogenic RAS. Solutions are unstable and should be fresh-prepared.	Exp Cell Res, 2026, 454(1):114825 Nature, 2025, 10.1038/s41586-025-09741-1 Cell, 2025, S0092-8674(25)00751-2
S3544	VBIT-4	VBIT-4 is a voltage-dependent anion channel (VDAC) oligomerization inhibitor that decreases mitochondrial DNA (mtDNA) release, type I interferon (IFN) signaling, neutrophil extracellular traps, and disease severity in a mouse model of systemic lupus erythematosus.	Cell Rep, 2025, 44(5):115605 Cell Rep, 2025, 44(6):115834 Aging Cell, 2025, 24(9):e70135
S8936	VBIT-12	VBIT-12 is a potent inhibitor of Voltage-dependent anion-selective channel 1 (VDAC1), directly interacting with purified VDAC1, reducing its channel conductance and preventing VDAC1 oligomerization.	PLoS Pathog, 2025, 21(1):e1012872 Heliyon, 2024, 10(1):e23426 Exp Cell Res, 2024, 434(2):113874
S0231	NSC15364	NSC 15364 (compound 59) is an inhibitor that directly interacts with VDAC1 and prevents VDAC1 oligomerization, concomitant with an inhibition of apoptosis.	Exp Cell Res, 2024, 434(2):113874
E5770	DIDS sodium salt	DIDS sodium salt (MDL101114ZA) is a pharmacological inhibitor of voltage-dependent anion channel 1 (VDAC1), which effectively suppresses apoptosis in THP-1 macrophages. It also acts as an antagonist of ABCA1 and inhibits RAD51-mediated homologous pairing and strand exchange reactions.
S3544	VBIT-4	VBIT-4 is a voltage-dependent anion channel (VDAC) oligomerization inhibitor that decreases mitochondrial DNA (mtDNA) release, type I interferon (IFN) signaling, neutrophil extracellular traps, and disease severity in a mouse model of systemic lupus erythematosus.	Cell Rep, 2025, 44(5):115605 Cell Rep, 2025, 44(6):115834 Aging Cell, 2025, 24(9):e70135
S8936	VBIT-12	VBIT-12 is a potent inhibitor of Voltage-dependent anion-selective channel 1 (VDAC1), directly interacting with purified VDAC1, reducing its channel conductance and preventing VDAC1 oligomerization.	PLoS Pathog, 2025, 21(1):e1012872 Heliyon, 2024, 10(1):e23426 Exp Cell Res, 2024, 434(2):113874
S0231	NSC15364	NSC 15364 (compound 59) is an inhibitor that directly interacts with VDAC1 and prevents VDAC1 oligomerization, concomitant with an inhibition of apoptosis.	Exp Cell Res, 2024, 434(2):113874
E5770	DIDS sodium salt	DIDS sodium salt (MDL101114ZA) is a pharmacological inhibitor of voltage-dependent anion channel 1 (VDAC1), which effectively suppresses apoptosis in THP-1 macrophages. It also acts as an antagonist of ABCA1 and inhibits RAD51-mediated homologous pairing and strand exchange reactions.
S7242	Erastin	Erastin is a ferroptosis activator by acting on mitochondrial VDAC, exhibiting selectivity for tumor cells bearing oncogenic RAS. Solutions are unstable and should be fresh-prepared.	Exp Cell Res, 2026, 454(1):114825 Nature, 2025, 10.1038/s41586-025-09741-1 Cell, 2025, S0092-8674(25)00751-2