Wee1

シグナル伝達経路

研究分野

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S1525 Adavosertib (MK-1775) 0.0001 mg/mL 80 mg/mL ''10 mg/mL
S8148 PD0166285 <1 mg/mL 100 mg/mL '100 mg/mL

Wee1製品

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S1525

Adavosertib (MK-1775)

Adavosertib (MK-1775, AZD1775) is a potent and selective Wee1 inhibitor with IC50 of 5.2 nM in a cell-free assay; hinders G2 DNA damage checkpoint. Phase 2.

S8148

PD0166285

PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations (IC50=24 nM for Wee1 and 72 nM for Myt1). PD0166285 is also a novel G2 checkpoint abrogator. PD0166285 induces apoptosis.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S1525

Adavosertib (MK-1775)

Adavosertib (MK-1775, AZD1775) is a potent and selective Wee1 inhibitor with IC50 of 5.2 nM in a cell-free assay; hinders G2 DNA damage checkpoint. Phase 2.

S8148

PD0166285

PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations (IC50=24 nM for Wee1 and 72 nM for Myt1). PD0166285 is also a novel G2 checkpoint abrogator. PD0166285 induces apoptosis.