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CaSR

CaSR製品

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  • CaSR活性剤(2)
  • CaSR拮抗剤(1)
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製品コード 製品名称 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S2633 NPS-2143 NPS-2143 (SB262470) is a novel potent and selective antagonist of Ca(2+) receptor with IC50 of 43 nM.
Biomed Pharmacother, 2023, 163:114843
Toxins (Basel), 2023, 16(1)21
Kaohsiung J Med Sci, 2022, 10.1002/kjm2.12601
NPS-2143-S2633Z0120150119.gif
S1260 Cinacalcet (AMG-073) HCl Cinacalcet (Mimpara, Sensipar,AMG-073) HCl represents a new class of compounds for the treatment of hyperparathyroidism.
Int J Mol Sci, 2022, 23(8)4323
Int J Mol Sci, 2020, 21(20)E7617
Mol Cell Endocrinol, 2020, 501:110654
Cinacalcet-S126001H0120190505.gif
E0359 Evocalcet Evocalcet (KHK7580) is an novel oral calcimimetic agent which acts via allosteric activation of the calcium sensing receptor (CaSR). Evocalcet (0, 20 and 60 nM) dose-dependently increases cytoplasmic [Ca2+] concentrations with an EC50 value of 92.7 nM in hCaR-HEK293 cells.
S1260 Cinacalcet (AMG-073) HCl Cinacalcet (Mimpara, Sensipar,AMG-073) HCl represents a new class of compounds for the treatment of hyperparathyroidism.
Int J Mol Sci, 2022, 23(8)4323
Int J Mol Sci, 2020, 21(20)E7617
Mol Cell Endocrinol, 2020, 501:110654
 Cinacalcet-S126001H0120190505.gif
E0359 Evocalcet Evocalcet (KHK7580) is an novel oral calcimimetic agent which acts via allosteric activation of the calcium sensing receptor (CaSR). Evocalcet (0, 20 and 60 nM) dose-dependently increases cytoplasmic [Ca2+] concentrations with an EC50 value of 92.7 nM in hCaR-HEK293 cells.
S2633 NPS-2143 NPS-2143 (SB262470) is a novel potent and selective antagonist of Ca(2+) receptor with IC50 of 43 nM.
Biomed Pharmacother, 2023, 163:114843
Toxins (Basel), 2023, 16(1)21
Kaohsiung J Med Sci, 2022, 10.1002/kjm2.12601
 NPS-2143-S2633Z0120150119.gif

CaSRシグナル伝達経路

united states