DNA alkylator

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S1312 Streptozotocin (STZ) 53 mg/mL 53 mg/mL <1 mg/mL
S1692 Busulfan <1 mg/mL 49 mg/mL <1 mg/mL
S2057 Cyclophosphamide Monohydrate 7 mg/mL 55 mg/mL <1 mg/mL
S1278 Altretamine <1 mg/mL 15 mg/mL 33 mg/mL
S7829 CB1954 <1 mg/mL 50 mg/mL <1 mg/mL
S5840 Palifosfamide 13 mg/mL 44 mg/mL 2 mg/mL
S8266 Melphalan <1 mg/mL 10 mg/mL <1 mg/mL

DNA alkylator製品

新DNA alkylator製品
製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S1312

Streptozotocin (STZ)

Streptozotocin is a glucosamine-nitrosourea derivative, which is a methylating, carcinogenic, antibiotic and diabetes inducing agent.

S1692

Busulfan

Busulfan is a cell cycle non-specific alkylating antineoplastic agent.

S2057

Cyclophosphamide Monohydrate

Cyclophosphamide Monohydrate is a nitrogen mustard alkylating agent, it attaches the alkyl group to the guanine base of DNA, shown to crosslink DNA, causing strand breakage and inducing mutations.

S1278

Altretamine

Altretamine is an anti-neoplastic agent.

S7829

CB1954

CB1954(Tretazicar) is a anticancer prodrug that is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent. It can be activated by NAD(P)H quinone oxidoreductase 2.

S5840

Palifosfamide

S8266

Melphalan

Melphalan is a phenylalanine derivative of nitrogen mustard with antineoplastic activity.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S1312

Streptozotocin (STZ)

Streptozotocin is a glucosamine-nitrosourea derivative, which is a methylating, carcinogenic, antibiotic and diabetes inducing agent.

2017, 17(3):411-418

2018, 106(1):1-19

S1692

Busulfan

Busulfan is a cell cycle non-specific alkylating antineoplastic agent.

2017, 403:74-85

S2057

Cyclophosphamide Monohydrate

Cyclophosphamide Monohydrate is a nitrogen mustard alkylating agent, it attaches the alkyl group to the guanine base of DNA, shown to crosslink DNA, causing strand breakage and inducing mutations.

2013, 73(20):6310-22

2018, 18:118

2017, 403:74-85

S1278

Altretamine

Altretamine is an anti-neoplastic agent.

S7829

CB1954

CB1954(Tretazicar) is a anticancer prodrug that is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent. It can be activated by NAD(P)H quinone oxidoreductase 2.

S5840

Palifosfamide

S8266

Melphalan

Melphalan is a phenylalanine derivative of nitrogen mustard with antineoplastic activity.

2018, 10.1158/1078-0432.CCR-18-1776