- 阻害剤
- 研究分野別
- PI3K/Akt/mTOR
- Epigenetics
- Methylation
- Immunology & Inflammation
- Protein Tyrosine Kinase
- Angiogenesis
- Apoptosis
- Autophagy
- ER stress & UPR
- JAK/STAT
- MAPK
- Cytoskeletal Signaling
- Cell Cycle
- TGF-beta/Smad
- 化合物ライブラリー
- 抗体
- 新製品
- お問い合わせ
Antibiotics
Antibiotics製品
- All (209)
- Antibiotics阻害剤 (27)
- 新製品
| 製品コード | 製品名称 | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|---|
| S1208 | Doxorubicin (Adriamycin) Hydrochloride | ドキソルビチン塩酸塩 (Doxorubicin (Adriamycin, NSC 123127, DOX, Hydroxydaunorubicin) HCl) は抗生物質の一種であり、DNA トポイソメラーゼ (topoisomerase) II を阻害することで DNA 損傷を引き起こし、がん細胞中においてマイトファジー (mitophagy) およびアポトーシス (apoptosis) を誘導します。ドキソルビシンは AMPK の 基底状態におけるリン酸化を減弱します。また、ドキソルビシンは HIV 感染患者の併用療法において使用されますが、同時に HBV 再活性化のリスクを伴うことが分かっています。This product may precipitate when dissolved in PBS solution. It is recommended to prepare the stock solution in pure water and dilute with either pure water or saline to obtain the working solution. |
|
|
| S7417 | Puromycin Dihydrochloride | Puromycin 2HCl is an aminonucleoside antibiotic derived from Streptomyces alboniger. It is an inhibitor of protein synthesis and has been used to study transcription regulatory mechanisms that control the sequential and coordinated expression of genes during cell differentiation. | ||
| S7046 | Brefeldin A (BFA chemical) | Brefeldin A (BFA)は、HCT 116細胞におけるIC50が0.2 μMのタンパク質輸送に対するラクトン系抗生物質およびATPase阻害剤であり、がん細胞の分化とアポトーシスを誘導します。また、HDR（相同組換え修復）効率を向上させ、CRISPRを介したHDRのエンハンサーとなる可能性もあります。Brefeldin Aは、オートファジーおよびマイトファジーの阻害剤でもあります。 |
|
|
| S5159 | Doxycycline | Doxycycline (Vibramycin, Doxytetracycline, Doxiciclina, Doxycyclinum) is an antibiotic that is used in the treatment of a number of types of infections caused by bacteria and protozoa. Doxycycline is also a nonspecific matrix metalloproteinase (MMP) inhibitor. | ||
| S1228 | Idarubicin HCl | Idarubicin HCl (4-demethoxydaunorubicin (NSC256439, 4-DMDR) HCl) は、Idarubicin の塩酸塩型で、アントラサイクリン系のAntibioticsであり、細胞を含まないアッセイでMCF-7細胞に対するIC50が3.3 ng/mLのDNA Topoisomerase II (topo II)阻害剤です。Idarubicin は、mTOR依存性の細胞毒性Autophagyを誘導します。 |
|
|
| S4226 | Minocycline HCl | Minocycline HClは、最も脂溶性が高く、最も活性の高いテトラサイクリン系抗生物質で、30Sリボソームサブユニットに結合し、tRNAのmRNA-リボソーム複合体への結合を妨げ、タンパク質合成を阻害します。 | ||
| S7419 | Blasticidin S Hydrochloride | Blasticidin S HCl is a nucleoside antibiotic isolated from Stretomyces girseochromogenes. It acts by blocking hydrolysis of peptidyl-tRNA induced by release factors and inhibits peptide bond formation. It is used to select transfected cells carrying bsr or BSD resistance genes. | ||
| S3028 | G418 Sulfate (Geneticin) | アミノグリコシド系の抗生物質であるGeneticin (G418 Sulfate) は、原核細胞と真核細胞の両方で伸長段階を阻害することにより、ポリペプチド合成を阻害する80 Sリボソームの伸長阻害剤です。 | ||
| S1835 | Azithromycin | Azithromycinは、タンパク質合成を阻害することにより機能するAntibioticsであり、Bacterial感染症の治療に用いられます。 | ||
| E4996 | Puromycin | Puromycin (CL13900, Puromycine) is an antibiotic, analog of the 3' end of aminoacyl-tRNA and an inhibitor of protein synthesis that mimics tyrosyl-tRNA, causing premature termination of translation. It blocks translation by labeling and releasing elongating polypeptide chains from ribosomes and has been widely used in molecular biology research. | ||
| S1373 | Daptomycin | Daptomycinは、グラム陽性菌に対し迅速なin vitro殺菌活性を有する新規のAntibioticsです。 |
|
|
| S1408 | Linezolid (PNU-100766) | Linezolid (PNU-100766)は、重篤な感染症の治療に使用される合成Antibioticsです。 |
|
|
| E2894 | Penicillin-Streptomycin | Penicillin-Streptomycin is used to prevent microbial contamination of cell culture during long-term in vitro cell culture maintenance. | ||
| S1636 | Amphotericin B | Amphotericin B (AMB、NSC 527017) は、エルゴステロール含有膜を透過させる両親媒性ポリエン Antibiotics です。 | ||
| S6068 | Doxycycline monohydrate | Doxycycline is a synthetic, broad-spectrum tetracycline antibiotic exhibiting antimicrobial activity. | ||
| S2908 | Hygromycin B | Hygromycin B（Hygrovetine）は、ほとんどの細菌、真菌、および高等真核生物に有効な選択的抗生物質であり、70Sリボソームでの転位を妨害し、誤った翻訳を引き起こすことによりタンパク質合成を阻害します。 | ||
| S2527 | Methacycline HCl | Methacycline HCl（Rondomycin）はテトラサイクリン系Antibioticsであり、約5 μMのIC50を持つ上皮間葉転換（EMT）阻害剤でもあり、さまざまな感染症の治療に使用されます。 | ||
| S7894 | Tunicamycin | Tunicamycin, an antibiotic, can potently inhibit the N-linked glycosylation (NLG) by competitively inhibiting UDP-GlcNAc-dolichol-phosphate N-acetylglucosamine-1 phosphate transferase (DPAGT1) activity and can target several types of tumors by reducing angiogenesis, inhibiting colony formation, and enhancing TRAIL-induced apoptosis. | ||
| S1741 | Rifabutin (LM427) | Rifabutin (LM427, Ansamycin) は、Mycobacterium avium intracellulare (MAI) および結核の治療に使用される半合成のansamycin系抗生物質です。 | ||
| S4030 | Gentamicin Sulfate | Gentamycin Sulfate（NSC-82261、SCH9724）は、感受性生物のタンパク質合成を阻害する、細胞培養に使用される広範囲のアミノグリコシド抗生物質です。Gentamicin Sulfateは、腎不全の動物モデルを誘発するために使用できます。 | ||
| S1450 | Nanchangmycin | Nanchangmycinは、ダイナマイシンと構造が類似したポリエーテル抗生物質であり、広範囲の有害な線虫や昆虫に対して非常に活性がありますが、哺乳類や植物には影響がありません。 | ||
| S7074 | Ionomycin | Ionomycin (SQ23377) is a potent and selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. It induces the activation of protein kinase C (PKC) and promotes apoptosis. | ||
| S1399 | Teicoplanin | Teicoplanin（Teichomycin、Targocid、MDL-507）は、グラム陽性Bacterialによる重篤な感染症の治療に使用されるグリコペプチドAntibioticsです。 | ||
| S2574 | Tetracycline HCl | Tetracycline HCl（NCI-c55561）は、広範囲スペクトルを有するポリケチド系Antibioticsであるテトラサイクリンの塩酸塩です。 | ||
| S3015 | Amoxicillin | Amoxicillin（アモキシシリン）は、感受性微生物によって引き起こされるBacterial感染症の治療に使用される、中程度のスペクトラムを持つ殺菌性のβ-ラクタムAntibioticsです。 | ||
| S5535 | Moxifloxacin | Moxifloxacin is an antibiotic used to treat a number of bacterial infections, active against Mycobacterium tuberculosis in vitro. | ||
| S1502 | Cephalexin | Cephalexin（セファレキシン）は、多くのBacterial感染症を治療できるAntibioticsです。 | ||
| S1635 | Erythromycin | Erythromycin（E-Mycin）は、ペニシリン（IC50=1.5 μg/ml）と同等か、わずかに広い抗菌スペクトルを持つマクロライド系のAntibioticsです。 | ||
| S2565 | Amoxicillin Sodium | Amoxicillin Sodium（Clavulanate, Amoxycillin sodium）は、中スペクトル、殺菌性のβ-ラクタム Antibioticsです。 | ||
| S5784 | Vancomycin | Vancomycin is an antibiotic used to treat serious bacterial infections. It works by stopping the growth of bacteria. | ||
| S1505 | Aztreonam | Aztreonam (SQ 26776) は合成モノサイクリックベータラクタムAntibioticsで、グラム陰性好気性Bacterial感染症の治療に使用されます。 | ||
| S2152 | Sitafloxacin Hydrate | Sitafloxacin Hydrate（DU-6859a）は、次世代の広範囲経口フルオロキノロン系Antibioticsです。 | ||
| S3129 | Trimethoprim | Trimethoprim (BW 56-72, NIH 204, NSC-106568) は、主に尿路感染症の予防と治療に用いられる静菌性抗生物質です。 | ||
| S4056 | Retapamulin | Retapamulin (SB-275833) は、大腸菌と黄色ブドウ球菌のリボソームの両方に同程度の力価で結合する局所抗生物質であり、Kd は 3 nM です。 | ||
| S3122 | Amikacin hydrate | Amikacin(BAY416651 hydrate)は、さまざまな種類の細菌感染症の治療に使用されるアミノグリコシド系抗生物質です。 | ||
| S4848 | Dalbavancin | Dalbavancin is a lipoglycopeptide antibiotic that has bactericidal activity against Gram-positive bacteria including various staphylococci. | ||
| S4490 | Tetracycline | Tetracycline (TC) is a broad-spectrum antibiotic that exhibits activity against a wide range of microorganisms including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, rickettsiae, and protozoan parasites. | ||
| S4148 | Ampicillin Trihydrate | Ampicillin Trihydrate (NCI-C56086、D-(-)-α-アミノベンジルペニシリン三水和物) は、細菌の細胞膜内表面にあるトランスペプチダーゼを不活性化することにより、細菌の細胞壁合成 (ペプチドグリカン架橋) を阻害するβ-ラクタム系抗生物質です。 | ||
| S4720 | Cefotaxime | Cefotaxime(HR-756) is a third-generation cephalosporin antibiotic and has broad spectrum activity against Gram positive and Gram negative bacteria. | ||
| S6010 | Sodium L-lactate | Sodium L-lactate is used as a food additive, preservative, acidity regulator and bulking agent. | ||
| S5206 | Benzylpenicillin potassium | Benzylpenicillin potassium (Penicillin G potassium) is the potassium salt form of penicillin G, a broad-spectrum penicillin antibiotic. | ||
| S3170 | Ampicillin sodium | Ampicillin(D-(-)-α-Aminobenzylpenicillin sodium salt) は、アミノペニシリンファミリーに属するβ-ラクタム系抗生物質です。 | ||
| S4279 | Demeclocycline HCl | Demeclocycline HCl(Demeclocycline hydrochloride) is a tetracycline antibiotic via inhibition of protein synthesis by bacteria, used for the treatment of bacterial infections. | ||
| S1773 | Oxytetracycline (Terramycin) | Oxytetracycline(Terramycin) は、Bacterial 感染症の治療に使用される広域テトラサイクリン系 Antibiotics です。 |
|
|
| S2506 | Roxithromycin | Roxithromycin (Roxl-150, Roxo, Surlid, Rulide, Biaxsig, Roxar, Roximycin, Roxomycin, Tirabicin, Coroxin, RU-28965)は半合成マクロライドAntibioticsです。これは、呼吸器、尿路、および軟部組織の感染症の治療に使用されます。 | ||
| S4093 | Bismuth Subcitrate Potassium | Bismuth Subcitrateは、細菌感染症であるヘリコバクター・ピロリに関連する胃潰瘍の治療に使用される抗生物質です。 | ||
| S5531 | Doripenem | Doripenem(S 4661) is a new parenteral carbapenem antibiotic with broad-spectrum activity against gram-negative and gram-positive pathogens. | ||
| S5268 | Solithromycin | Solithromycin (CEM-101, OP-1068), belonging to the well-known class of macrolide antibiotics that also includes azithromycin, is a potent bacterial protein synthesis inhibitor. | ||
| S4158 | Ceftriaxone disodium salt hemi (heptahydrate) | Ceftriaxone disodium salt hemi (heptahydrate)は、第三世代セファロスポリン系抗生物質です。 | ||
| S4160 | Penicillin G Sodium | Penicillin G Sodium（ベンジルペニシリン）は、Penicillin spp.によって産生されるβ-ラクタム系抗生物質です。 | ||
| S1395 | Polymyxin B sulphate | Polymyxin B (Aerosporin, PMB, Poly-RX) は、主に薬剤耐性グラム陰性菌感染症に使用されるAntibioticsです。 | ||
| S4641 | Tedizolid Phosphate | Tedizolid (TR-701FA) is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid. | ||
| S5298 | Amoxicillin trihydrate | Amoxicillin (Amoxil, Amoxipen, Moxaline) is a broad-spectrum, semisynthetic aminopenicillin antibiotic with bactericidal activity. | ||
| S2315 | Kanamycin sulfate | Kanamycin sulfate（Kanamycin monosulfate、Ophtalmokalixan）は、経口、静脈内、筋肉内投与が可能なaminoglycoside antibioticであり、幅広い感染症の治療に使用されます。 | ||
| S4215 | Ribostamycin Sulfate | Ribostamycin Sulfate（Vistamycin Sulfate、Landamycine）は、中性糖部分を含むアミノグリコシド系抗生物質で、Streptomyces ribosidificusによって産生されます。 | ||
| S4222 | Piperacillin Sodium | Piperacillin (CL227193, Pipracil) は、緑膿菌感染症を対象とした、アンピシリン由来の広範囲スペクトルを有する半合成ウレイ ドペニシリン系抗生物質です。 | ||
| S5208 | Ciprofloxacin hydrochloride hydrate | Ciprofloxacin Hydrochloride (Ciloxan, Ceprimax, Oftacilox,Bay-09867 hydrochloride hydrate) is the hydrochloride salt form of ciprofloxacin, which is an antibiotic used to treat a number of bacterial infections. | ||
| S4783 | Benzyl isothiocyanate | Benzyl isothiocyanate (BITC, Benzoylthiocarbimide, Isothiocyanic Acid Benzoyl Ester) is an isothiocyanate originally found in cruciferous vegetables that exhibits immunomodulatory, anti-parasitic, antibiotic, antioxidative, anti-atherosclerotic, anti-angiogenic, anti-metastatic, anticancer chemotherapeutic, and chemopreventive activities. | ||
| S1374 | Doripenem Hydrate | Doripenem Hydrate（S-4661）は、複雑な腹腔内感染症および複雑な尿路感染症の治療に使用される超広域スペクトル注射用Antibioticsです。 | ||
| S1381 | Meropenem | Meropenem (SM 7338)は、超広域スペクトル注射用Antibioticsです。 | ||
| S2510 | Spectinomycin 2HCl | Spectinomycin 2HCl (Actinospectacin) は、Streptomyces spectabilis から調製された新しい非経口Antibioticsです。 | ||
| S1605 | Cefdinir | Cefdinir（FK 482、PD 134393、CI-983）は、体内の様々な部位におけるBacterial感染症の治療に用いられる経口セファロスポリン系Antibioticsである。 | ||
| S2568 | Neomycin sulfate | Neomycin sulfate（フラマイセチン硫酸塩）はアミノグリコシド系の抗生物質で、細菌感染症の治療に使用されます。 | ||
| S4052 | Netilmicin Sulfate | Netilmicin Sulfateはアミノグリコシド系抗生物質の一種です。 | ||
| S4082 | Spiramycin | Spiramycin（Formacidine）は16員環マクロライド（抗生物質）です。 | ||
| S2514 | Tobramycin | Tobramycin (NSC 180514, Deoxykanamycin B, Nebramycin Factor 6) は、IC50 が 9.7 µM の aminoglycoside antibiotic です。 | ||
| S3059 | Enrofloxacin | Enrofloxacin（BAY-Vp2674、PD160788）はフルオロキノロン系抗生物質です。 | ||
| S2539 | Lomefloxacin HCl | Lomefloxacin HClはロメフロキサシンの塩酸塩であり、フルオロキノロン系のAntibioticsです。 | ||
| S3105 | Nadifloxacin | Nadifloxacin（OPC-7251）は、ざ瘡治療のための局所フルオロキノロン系抗生物質です。 | ||
| S4234 | Capreomycin Sulfate | Capreomycin Sulfateは環状ペプチド抗生物質であり、70Sリボソームユニットに結合することでタンパク質合成を阻害すると考えられています。 | ||
| S5051 | Pipemidic acid | Pipemidic acid (Acido pipemidico) is a pyridopyrimidine antibiotic derivative of piromidic acid with activity against gram-negative bacteria including Pseudomonas aeruginosa and some gram-positive bacteria. Pipemidic acid is an inhibitor of DNA gyrase that is a bacterial enzyme which catalyzes the ATP-dependent negative supercoiling of DNA. It can be used for the research of intestinal, urinary, and biliary tract infections. | ||
| S5328 | Gamithromycin | Gamithromycin (ML-1709460) is a new macrolide antibiotic that is only registered for use in cattle to treat respiratory disorders such as bovine respiratory disease. | ||
| S5199 | Oxytetracycline hydrochloride | Oxytetracycline (OTC, Oxycycin, Stevacin, Terramycin) hydrochloride is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins. | ||
| S2583 | Thiamphenicol | Thiamphenicol (Thiophenicol,Dextrosulphenidol)は、抗菌性のAntibioticsであり、クロラムフェニコールのメチルスルホニルアナログです。 | ||
| S5533 | Tobramycin sulfate | Tobramycin sulfate is the sulfate salt of tobramycin, an aminoglycoside antibiotic derived from the bacterium Streptomyces tenebrarius with bactericidal activity. | ||
| S3971 | Fusidine | Fusidine (Fusidic Acid), isolated from Fusidium coccineum, is a steroidal antibiotic that inhibits protein synthesis. | ||
| S5008 | Ciprofloxacin (CPX) hydrochloride | Ciprofloxacin (CPX) hydrochloride, a fluorinated quinolone, is a β-diketone antibiotic with a broad spectrum antibacterial activity. Ciprofloxacin is an inhibitor of bacterial DNA gyrase (a subclass of Type II topoisomerases). | ||
| S2052 | Oxytetracycline Dihydrate | Oxytetracycline Dihydrateは、細菌が必須タンパク質を生成する能力を妨げる処方箋抗生物質です。 | ||
| S3496 | Lefamulin acetate (Xenleta) | Lefamulin acetate (Xenleta, BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, thus preventing the binding of transfer RNA for peptide transfer. | ||
| S5491 | Lomefloxacin | Lomefloxacin(SC47111A) is a fluoroquinolone antibiotic used to treat bacterial infections. | ||
| S4885 | Taurolidine | Taurolidine (Taurolin, Tauroline, Tauroflex) is a synthetic broad-spectrum antibiotic with antibacterial, anticoagulant and potential antiangiogenic activities. | ||
| S6549 | PBTZ169 | PBTZ169 (macozinone), an antibiotic with antimycobacterial activity, is an irreversible inhibitor of DprE1. | ||
| S4183 | Paromomycin Sulfate | Paromomycin Sulfate（アミノシジン硫酸塩）は、16SリボソームRNAに結合することにより、非耐性細胞のタンパク質合成を阻害するアミノグリコシド系抗生物質です。 | ||
| S5644 | Ceftriaxone Sodium | Ceftriaxone Sodium is the sodium salt form of ceftriaxone, a beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity. | ||
| S5330 | Amikacin Sulfate Salt | Amikacin (BAY 41-6551) sulfate, a semisynthetic analog of kanamycin, is an aminoglycoside antibiotic which is very active against most gram-negative bacteria including gentamicin- and tobramycin-resistant strains. | ||
| S6423 | Tildipirosin | Tildipirosin is a 16-membered ring, tribasic and semi-synthetic macrolide antibiotic. | ||
| S4986 | Latamoxef sodium | Latamoxef sodium (Moxalactam Disodium, FestamoxinLy, Shiomarin, Ly 127935, 6059 S) is an antibiotic and has anti-bacterial and anti-inflammation effects. | ||
| E8174 | Streptomycin | Streptomycin (Agrept, Agrimycin, Streptomycin A) is an aminoglycoside antibiotic isolated from Streptomyces griseus and used in tuberculosis (TB) research due to its activity against Mycobacterium tuberculosis. It is also a bactericidal agent useful for studying various bacterial infections. | ||
| S5410 | Chloramphenicol sodium succinate | Chloramphenicol Sodium Succinate is the sodium succinate salt form of chloramphenicol, a nitrobenzene derivate and broad-spectrum antibiotic with antibacterial activity. | ||
| S4517 | Cefotaxime sodium | Cefotaxime sodium salt(HR-756) is a third-generation cephalosporin antibiotic; broad-spectrum antibiotic with activity against numerous Gram-positive and Gram-negative bacteria. | ||
| S4833 | Cefoxitin sodium | Cefoxitin Sodium is the sodium salt form of cefoxitin, a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. | ||
| S4536 | Nitrofurantoin | Nitrofurantoin (Macrodantin, Furadantine, Furadonine) is an antibiotic used to treat bladder infections.It inhibits bacterial DNA, RNA, and cell wall protein synthesis. | ||
| S1370 | Biapenem | Biapenem (L-627, LJC10627)は、グラム陽性菌株とグラム陰性菌株の両方に対して活性を持つカルバペネム系のAntibioticsです。 | ||
| S1371 | Cefoselis Sulfate | Cefoselis（FK 037 Sulfate）は、広く使用されているベータラクタム系のAntibioticsです。 | ||
| S2159 | Tebipenem Pivoxil (L084) | Tebipenem Pivoxil (L-084, ME1211,TBPM-PI,LJC 11036)は、耳鼻咽喉科および呼吸器感染症の治療に使用される経口carbapenem Antibioticsです。 | ||
| S1768 | Cefditoren Pivoxil | Cefditoren Pivoxil（ME-1207）は、Gram陰性およびGram陽性のBacterialに対する広域Antibioticsです。 | ||
| S1998 | D-Cycloserine | D-Cycloserine（RO-1-9213）はアミノ酸D-アラニンのアナログであり、結核治療におけるAntibioticsとして使用されます。 | ||
| S1611 | Cefoperazone | Cefoperazone は、rMrp2 を介した [3H]E217βG 取り込みを 199 μM の IC50 で阻害するセファロスポリン系 Antibiotics です。 | ||
| S1777 | Ethionamide | Ethionamide (Bayer 5312) は、結核の治療に用いられるantibioticです。 | ||
| S2544 | Cefprozil hydrate | Cefprozil hydrate は、気管支炎、耳、喉、副鼻腔、皮膚の感染症など、細菌によって引き起こされる特定の感染症の治療に使用される半合成広域スペクトルantibioticです。 | ||
| S2563 | Oxacillin sodium monohydrate | Oxacillin sodium monohydrate (Methicillin)は抗菌薬であり、ペニシリン系に属する狭スペクトルβ-ラクタムAntibioticsです。 | ||
| S1499 | Cefaclor monohydrate | Cefaclor monohydrate(Cefachlor, Cefaclorum)はセファロスポリン系のAntibioticsです。 | ||
| S1915 | Sulfamethoxazole | Sulfamethoxazole(Ro 4-2130)は、IC50が2.7 μMのスルホンアミド系静菌性Antibioticsです。 | ||
| S1791 | Bacitracin Zinc | Bacitracin (Zinc Bacitracin) は、ペプチドグリカン Bacterial 細胞壁の構成要素を内膜の外側に輸送する膜キャリア分子である C55-イソプレニルピロリン酸の脱リン酸化を阻害する Antibiotics です。IC50 10 μM で Met-エンケファリンからの Tyr の切断を阻害します。 | ||
| S2530 | 7-Aminocephalosporanic acid | 7-Aminocephalosporanic acidは、セファロスポリン系Antibioticsや中間体の合成に使用されます。 | ||
| S2543 | Ceftiofur HCl | Ceftiofur HCl（U-67279A、Excenel hydrochloride）は、グラム陽性菌とグラム陰性菌の両方の感染症の治療に使用されるセファロスポリン系Antibioticsです。 | ||
| S3162 | Tylosin tartrate | Tylosin tartrateは、家禽におけるマイコプラズマ症の制御が承認されているマクロライド系抗生物質です。 | ||
| S1770 | Sulfadiazine | Sulfadiazineはサルファ剤系のAntibioticsです。 | ||
| S2048 | Clindamycin Phosphate | Clindamycin Phosphate (NSC 618653) は、IC50が12 nMの熱帯熱マラリア原虫に対するリンコサミド系Antibioticsです。 | ||
| S3055 | Besifloxacin HCl | Besifloxacin HCl は、第4世代のフルオロキノロン系抗生物質です。 | ||
| S1977 | Sarafloxacin HCl | Sarafloxacin HCl (A-56620)は、IC50が0.96 μg/Lのキノロン系Antibioticsであるsarafloxacinの塩酸塩です。 | ||
| S4254 | Apramycin Sulfate | Apramycin Sulfate (Ai3-29795)は、RNAの深い溝に結合するアミノグリコシド系抗生物質です。 | ||
| S3179 | Carbenicillin disodium | Carbenicillin (BRL-2064,α-carboxybenzylpenicillin)は、グラム陰性菌の細胞壁合成を阻害する低毒性の半合成ペニシリン系抗生物質です。 | ||
| S3193 | Ticarcillin sodium | Ticarcillin（AB 2288、BRL 2288）は、多くのグラム陽性菌およびグラム陰性菌、好気性菌、嫌気性菌に対して幅広い殺菌活性を持つ半合成抗生物質です。 | ||
| S5227 | Erythromycin thiocyanate | Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits and inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins. | ||
| S5560 | Midecamycin | Midecamycin (Espinomycin A, Medecamycin A1, Platenomycin B1, Rubimycin, Turimycin P3) is a naturally occuring macrolide antibiotic that acts by inhibiting bacterial protein synthesis. | ||
| E6075New | Penicillin G benzathine tetrahydrate | Penicillin G benzathine tetrahydrate (Benzathine benzylpenicillin tetrahydrate) is a long-acting beta-lactam antibiotic effective against many bacterial infections such as impetigo. | ||
| S5048 | Fosfomycin Disodium | Fosfomycin (Phosphonemycin) is a bactericidal, low-molecular weight, broad-spectrum antibiotic, with putative activity against several bacteria, including multidrug-resistant Gram-negative bacteria, by irreversibly inhibiting an early stage in cell wall synthesis. | ||
| S5353 | Cefpiramide sodium | Cefpiramide sodium (CPMS, SM-1652,wy-44635) is an anionic β-lactam antibiotic. It exhibits antibacterial activity against gram-positive and gram-negative bacteria, in particular, to Pseudomonas aeruginosa, which can result in achronic life-threatening infection in the lungs of cystic fibrosis patients. | ||
| S5951 | Cefoxitin | Cefoxitin is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. | ||
| S4974 | Oxacillin sodium | Oxacillin sodium (salt) is a narrow-spectrum β-lactam antibiotic that can be used for treatment of methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia. | ||
| S5035 | 6-Aminopenicillanic acid | 6-Aminopenicillanic acid (6-APA) is the central component of penicillin β-lactam antibiotics which are generated by Penicillium. It is used as precursor for antibiotic compounds ampicillin and amoxicillin. | ||
| E8298New | Duocarmycin SA | Duocarmycin SA is a potent antitumor antibiotic with an IC50 of 10 pM. It is an extremely potent cytotoxic agent capable of inducing a sequence-selective alkylation of duplex DNA and can be used in research treatment for glioblastoma multiforme (GBM). | ||
| S4850 | Flucloxacillin sodium | Flucloxacillin sodium (Floxacillin sodium) is the sodium salt of flucloxacillin, a penicillin antibiotic used to treat bacterial infections. | ||
| S4594 | Cephalothin sodium | Cephalothin (Cefalotin, Cephalotin) sodium is a semisynthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalothin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. | ||
| S4865 | Cefetamet pivoxil hydrochloride | Cefetamet pivoxil hydrochloride is the hydrochloride salt form of cefetamet pivoxil, which is an oral third-generation cephalosporin antibiotic. | ||
| S5941 | Besifloxacin | Besifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial conjunctivitis. | ||
| S4979 | Procaine penicillin G | Penicillin G Procaine (PGP, Penicillin G Procaine, Bicillin C-R), a crystalline complex combining penicillin G with procaine, is a β-lactam antibiotic. | ||
| E4802 | Ticarcillin disodium | Ticarcillin disodium is a semisynthetic β-lactam antibiotic, which is active against Pseudomonas aeruginosa, Escherichia coli, Pseudomonas mirabilis, Pseudomonas rettgeri, and Klebsiella aerogenes. | ||
| S5278 | Tedizolid | Tedizolid is an oxazolidinone-class antibiotic prodrug used for the treatment of acute bacterial skin and skin structure infections caused by susceptible isolates of several Gram-positive bacteria. | ||
| S4122 | Tilmicosin | Tilmicosin (EL 870,LY-177370) はマクロライド系抗生物質です。 | ||
| S4869 | Sulfamethoxazole sodium | Sulfamethoxazole sodium is an antibiotic used for bacterial infections. | ||
| S5719 | Ceftizoxime sodium | Ceftizoxime sodium(SKF-88373) is a semisynthetic cephalosporin antibiotic that is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. | ||
| S5207 | Cephalexin Monohydrate | Cephalexin is a semisynthetic cephalosporin antibiotic with antimicrobial activity. | ||
| S4585 | Succinylsulfathiazole | Succinylsulfathiazole (Succinylsulphathiazole), a sulfonamide, is an antibiotic. | ||
| S8418 | Phleomycin D1 | Phleomycin D1(PLM D1), a glycopeptide antibiotic, is a member of the Bleomycin/Phleomycin family. It causes cell death by binding and cleaving DNA. It shows antiproliferative activities and strong cytotoxicity against HT-29 cells. | ||
| S4941 | Farnesol | Farnesol is a natural sesquiterpene alcohol that is potent in treating antimetabolic disorders, anti-inflammation, showing antioxidant, anticancer, and antibiotic effects. | ||
| S4595 | Cefazolin Sodium | Cefazolin Sodium (cefazoline, cephazolin, Ancef) is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine. | ||
| S5333 | Sulbenicillin Sodium | Sulbenicillin Sodium (Sulfocillin, Sulfobenzylpenicillin) is the sodium salt of sulbenicillin, which is a penicillin antibiotic. | ||
| S5936 | Cefazolin | Cefazolin(Cephazolin) is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine. | ||
| S4596 | Cefixime | Cefixime (Cefixima, Cefiximum, Cephoral, Cefspan, FR-17027, FK-027, CL-284635) is an antibiotic useful for the treatment of a number of bacterial infections. It is a third generation cephalosporin. | ||
| S4150 | Orbifloxacin | Orbifloxacin(CP-104354)は、合成広域フルオロキノロン系抗生物質です。 | ||
| S7784 | Fumagillin | Fumagillin(Amebacilin,NSC9168) is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis. | ||
| S4421 | Josamycin | Josamycin (EN-141, Kitasamycin A3, Leucomycin A3, Turimycin A5) is a macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens. | ||
| S5968 | Kasugamycin hydrochloride hydrate | Kasugamycin (Ksg) hydrochloride hydrate, an antibiotic which binds both the 30S and 70S ribosome, specifically inhibits translation initiation of canonical but not of leaderless messenger RNAs. | ||
| S4156 | Chlortetracycline HCl (NSC 13252) | Chlortetracycline HCl（NSC 13252、7-クロルテトラサイクリン、オーレオマイシン一塩酸塩）は、最初に同定されたテトラサイクリン系抗生物質です。 | ||
| S4647 | Cefmenoxime hydrochloride | Cefmenoxime (SCE-1365), a potent inhibitor of Enterobacteriaceae, is a cephalosporin antibiotic that is administered intravenously or intramuscularly. | ||
| S5296 | Cephradine monohydrate | Cefradine is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. | ||
| S5290 | Ormetoprim | Ormetoprim (OMP) is an antibiotic to prevent the spread of disease in freshwater aquaculture. | ||
| S5487 | Cefoperazone sodium | Cefoperazone(CP 52640-2) Sodium is the sodium salt form of cefoperazone, which is a semi-synthetic, broad-spectrum, beta-lactamase resistant antibiotic with bactericidal activity. | ||
| S5294 | Cephalotin acid | Cephalotin acid (Cephalothin, Cefalotin, Cephalothinum) is a cephalosporin antibiotic. | ||
| S5736 | Benzathine penicilline | Benzathine penicilline (Benzathine penicillin G) is an antibiotic useful for the treatment of a number of bacterial infections. | ||
| S4612 | Dapson | Dapson (Dapsone, 4,4′-Diaminodiphenyl sulfone, 4,4′-Sulfonyldianiline, 4-Aminophenyl sulfone, Bis(4-aminophenyl) sulfone, DDS), also known as diaminodiphenyl sulfone (DDS), is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy. | ||
| S1884 | Sparfloxacin | Sparfloxacin (AT-4140, CI-978, PD 131501,Zagam) はフルオロキノロン系のAntibioticsであり、広範囲で強力なantibacterial活性を示します。 | ||
| S2385 | Hordenine | Hordenine（N,N-ジメチル-4-ヒドロキシフェニルエチルアミン）は、抗菌作用とAntibiotics作用を持つフェニルエチルアミンアルカロイドです。 | ||
| S5601 | Balofloxacin Dihydrate | Balofloxacin Dihydrate is an orally active fluoroquinolone antibiotic. | ||
| S5417 | Spectinomycin dihydrochloride pentahydrate | Spectinomycin dihydrochloride pentahydrate (Trobicin) is a widely used antibiotic that inhibits bacterial protein synthesis by blocking translocation of messenger RNA and transfer RNAs on the ribosome. | ||
| S3645 | Kitasamycin | Kitasamycin (Leucomycin) is a macrolide antibiotic. It has antimicrobial activity against a wide spectrum of pathogens. | ||
| S6562 | KKL-35 | KKL-35 inhibits the trans-translation tagging reaction with an IC50 of 0.9 µM. It has broad-spectrum antibiotic activity. | ||
| E4877 | Lefamulin | Lefamulin (BC-3781), is a pleuromutilin antibiotic, inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome. It is effective against a range of gram-positive pathogens involved in community-acquired bacterial pneumonia (CABP), including Streptococcus pneumoniae, Haemophilus influenzae, Mycoplasma pneumoniae, Legionella pneumophila, Chlamydophila pneumoniae, Staphylococcus aureus (including methicillin-resistant and vancomycin-intermediate strains), and vancomycin-resistant Enterococcus faecium. | ||
| S4179 | Mezlocillin Sodium | Mezlocillin Sodiumは、感受性のある通常グラム陽性の生物によって引き起こされるBacterial感染症の治療に使用されるペニシリンベータラクタムAntibioticsです。 | ||
| S4060 | Erythromycin Ethylsuccinate | Streptomyces erythreusによって産生される経口マクロライド抗生物質であるErythromycin Ethylsuccinateは、細菌の50Sリボソームに可逆的に結合し、タンパク質合成を阻害します。 | ||
| S5515 | Penicillin G Procaine | Procaine benzylpenicillin (Procaine benzylpenicillin,PGP), also known as Procaine benzylpenicillin, is an antibiotic useful for the treatment of a number of bacterial infections. | ||
| S5637 | Cefotiam Hexetil Hydrochloride | Cefotiam Hexetil Hydrochloride is the hydrochloride salt of cefotiam hexetil. Cefotiam is a semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. | ||
| S5299 | Tosufloxacin p-Toluenesulfonate Hydrate | Tosufloxacin (T-3262) is a fluoroquinolone antibiotic that is used to treat susceptible infections. | ||
| S5295 | Lincomycin Hydrochloride Monohydrate | Lincomycin hydrochloride monohydrate is a narrow-spectrum antibiotic used in the treatment of staphylococcal, streptococcal, and Bacteroides fragilis infections. | ||
| S8871 | Omadacycline tosylate | Omadacycline tosylate(PTK 0796 tosylate,Amadacycline tosylate) is a first-in-class aminomethylcycline antibiotic, demonstrating antimicrobial activity in vitro against a range of Gram-positive and Gram-negative aerobes and some anaerobic bacteria. | ||
| S5420 | Clindamycin alcoholate | Clindamycin alcoholate is a crystallizable compound of Clindamycin with alcohol. Clindamycin is a semisynthetic lincosamide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits. | ||
| E4906 | Cefadroxil | Cefadroxil(BL-S 578) is a first-generation, cephalosporin antibiotic with broad spectrum of anti-bacterial activity. It can be used in the management of infections in the respiratory tract, urinary tract, skin and soft tissues, and bones and joints. | ||
| S5421 | Fluoroquinolonic Acid | Fluoroquinolonic Acid (Ciprofloxacin Impurity A, Q-Acid) is an antibiotic and antimicrobial agent. | ||
| S4750 | Sulfacetamide sodium salt hydrate | Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase(DHPS) with IC50 of 9.5 μM. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. | ||
| S6584 | Amdinocillin | Amdinocillin (Mecillinam, Coactin, FL 1060) is a β-lactam antibiotic with a broad spectrum of antibacterial activity. Amdinocillin is active alone against many gram-negative organisms. | ||
| S6582 | Ozenoxacin | Ozenoxacin(T-3912) is a quinolone antibiotic used for the treatment of impetigo. | ||
| S4870 | Cefodizime Sodium | Cefodizime Sodium, a third generation cephalosporin antibiotic, has broad-spectrum activity and is stable to most beta-lactamases. | ||
| S3636 | Cefadroxil hydrate | Cefadroxil(BL-S 578 hydrate) is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections. | ||
| E2890 | CHIR-090 | CHIR-090 is a potent and tight-binding inhibitor of the LpxC deacetylase. It also binds to E. coli LpxC with a Ki of 4.0 nM. | ||
| S4978 | Azathramycin | Azathramycin (Azaerythromycin A, Azaerythromycin) is a macrolide antibiotic containing cladinose. | ||
| S3708 | Sulfachloropyridazine | Sulfachloropyridazine is an antibiotic used to treat a variety of bacterial infections. | ||
| S4663 | Fusidate Sodium | Fusidate Sodium (Fucidin, SQ-16360) is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infections. | ||
| S5041 | Difloxacin hydrochloride | Difloxacin is a second-generation, synthetic fluoroquinolone antimicrobial antibiotic used in veterinary medicine. | ||
| S5657 | Ertapenem sodium | Ertapenem Sodium (MK826) is the sodium salt of ertapenem, a long-acting, broad-spectrum antibiotic of β-lactam subclass. | ||
| S4271 | Isepamicin Sulphate | Isepamicin Sulphate (Isepamicine, Isepamycin, sch21420) is an aminoglycoside antibiotic, which inhibits bacterial protein synthesis by targeting the bacterial 30S ribosomal subunit. | ||
| S3672 | Cefonicid sodium | Cefonicid sodium (Monocid) is a cephalosporin antibiotic. It interferes with cell wall biosynthesis in bacteria, leading to lysis of the infectious organism. | ||
| S4213 | Dirithromycin | Dirithromycin（LY-237216、ASE 136、Dynabac）は、70S Bacterialリボソームの50Sサブユニットに結合してペプチドの転位を阻害するマクロライド糖ペプチド抗生物質です。 | ||
| S4671 | Cefradine | Cefradine (Cephradine, Sefril, Anspor, Velosef) is a semi-synthetic cephalosporin antibiotic. | ||
| S5070 | Mupirocin calcium | Mupirocin Calcium (Pseudomonic acid A) is the calcium salt form of mupirocin, a natural crotonic acid derivative extracted from Pseudomonas fluorescens,which inhibits bacterial protein synthesis and is used as an antibiotic. | ||
| E6061New | Cefamandole sodium | Cefamandole (sodium) is a parenteral, broad-spectrum, second-generation cephalosporin antibiotic effective against various gram-positive and gram-negative bacteria, including Neisseria, Haemophilus, and Proteus species. | ||
| S3650 | Penicillin V potassium salt | Phenoxymethylpenicillin, also known as penicillin V, is an antibiotic useful for the treatment of a number of bacterial infections. It acts by inhibiting the biosynthesis of cell-wall peptidoglycan. | ||
| E4847 | Tosufloxacin | Tosufloxacin (A-61827) is an orally active fluoroquinolone antibiotic. Tosufloxacin effectively targets a broad spectrum of antibacterial activity, including both gram-positive and gram-negative strains. | ||
| E6052New | Enrofloxacin hydrochloride | Enrofloxacin hydrochloride is a fluoroquinolone antibiotic with potent activity against Mycoplasma bovis, showing an MIC₉₀ of 0.312 μg/mL. It can be used in research to study treatments for pneumonia, mastitis, arthritis, and other conditions in cattle. | ||
| E0706 | Gemifloxacin mesylate | Gemifloxacin mesylate (SB265805 mesylate, LB20304 mesylate) is a novel fluoronaphthyridone with a broad spectrum of antimicrobial activity and enhances activity against gram-positive aerobes. | ||
| E0656 | 7-Methylcoumarin | 7-Methylcoumarin can inhibit the growth of S. aureus and the growth of Gram-positive bacteria within a concentration of 0.8–3.6 μg/ml, and also has a strong hepatoprotective activity. | ||
| S5573 | Tilmicosin phosphate | Tilmicosin phosphate is a macrolide antibiotic that is used to treat cattle for pathogens that cause Bovine Respiratory Disease. | ||
| S4523 | Dihydrostreptomycin sulfate | Dihydrostreptomycin sulfate is an aminoglycoside antibiotic, used to treat bacterial diseases in cattle, pigs and sheep. Dihydrostreptomycin is a derivative of streptomycin. | ||
| S5473 | Pivmecillinam hydrochloride | Pivmecillinam is a β-lactam antibiotic and a prodrug of mecillinam. It has selective activity against Gram-negative bacteria and is used primarily in the treatment of lower urinary tract infections. | ||
| S5350 | Cefpodoxime proxetil | Cefpodoxime Proxetil is a third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. | ||
| S4540 | Sisomicin sulfate | Sisomicin sulfate is an aminoglycoside antibiotic, isolated from the fermentation broth of a new species of the genus Micromonospora. | ||
| E7524 | G-418 | G-418 (Geneticin, Antibiotic G-418) is an aminoglycoside antibiotic originally isolated from Micromonospora rhodorangea. It functions by binding to the ribosomal subunit, thereby inhibiting translational elongation and disrupting protein synthesis in both prokaryotic and eukaryotic cells, thus impairing cell growth and viability. | ||
| S4425 | Rifamycin S | Rifamycin S, a quinone and an antibiotic against Gram-positive bacteria (including MRSA), is a clinical drug used to treat tuberculosis and leprosy. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation. | ||
| S5744 | Spiramycin I | Spiramycin I (Foromacidin A) is a main component of spiramycin, which is a macrolide antimicrobial agent with broad spectrum antibiotic activity. | ||
| S4813 | Cefuroxime axetil | Cefuroxime axetil, a prodrug of the cephalosporin cefuroxime, is a second generation oral cephalosporin antibiotic with in vitro antibacterial activity against several gram-positive and gram-negative organisms. | ||
| S4436 | Pleuromutilin | Pleuromutilin (Drosophilin B, Mutilin 14-glycolate), the lead compound for novel antibiotics, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria. | ||
| S4393 | Cephapirin Sodium | Cephapirin Sodium（セファピリン）は、殺菌活性を持つ半合成の第一世代セファロスポリン系抗生物質であるセファピリンのナトリウム塩です。Cephapirin Sodiumはグラム陰性菌とグラム陽性菌に対して有効です。 | ||
| S5351 | Cefmetazole sodium | Cefmetazole sodium is a semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. | ||
| S5859 | Sancycline | Sancycline (Bonomycin, Norcycline, GS 2147) is a semi-synthetic tetracycline antibiotic. | ||
| S4812 | Ceftizoxime | Ceftizoxime is a semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. It is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. | ||
| S4488 | Delafloxacin Meglumine | Delafloxacin (ABT-492, RX-3341, WQ-3034, Baxdela) meglumine is a broad-spectrum fluoroquinolone antibiotic against multiple pathogens. | ||
| S5108 | Tylosin | Tylosin (Fradizine, Tylocine, Tylosine, Tylosin A) is a macrolide-class broad spectrum antibiotic that's used in veterinary medicine to treat felines, canines and livestock. | ||
| S4847 | Faropenem Sodium | Faropenem sodium is an orally active beta-lactam antibiotic that has been used in trials studying the treatment of Tuberculosis, Pulmonary Tuberculosis, and Community Acquired Pneumonia. | ||
| S7417 | Puromycin Dihydrochloride | Puromycin 2HCl is an aminonucleoside antibiotic derived from Streptomyces alboniger. It is an inhibitor of protein synthesis and has been used to study transcription regulatory mechanisms that control the sequential and coordinated expression of genes during cell differentiation. | ||
| S7046 | Brefeldin A (BFA chemical) | Brefeldin A (BFA)は、HCT 116細胞におけるIC50が0.2 μMのタンパク質輸送に対するラクトン系抗生物質およびATPase阻害剤であり、がん細胞の分化とアポトーシスを誘導します。また、HDR（相同組換え修復）効率を向上させ、CRISPRを介したHDRのエンハンサーとなる可能性もあります。Brefeldin Aは、オートファジーおよびマイトファジーの阻害剤でもあります。 |
|
|
| S1228 | Idarubicin HCl | Idarubicin HCl (4-demethoxydaunorubicin (NSC256439, 4-DMDR) HCl) は、Idarubicin の塩酸塩型で、アントラサイクリン系のAntibioticsであり、細胞を含まないアッセイでMCF-7細胞に対するIC50が3.3 ng/mLのDNA Topoisomerase II (topo II)阻害剤です。Idarubicin は、mTOR依存性の細胞毒性Autophagyを誘導します。 |
|
|
| E4996 | Puromycin | Puromycin (CL13900, Puromycine) is an antibiotic, analog of the 3' end of aminoacyl-tRNA and an inhibitor of protein synthesis that mimics tyrosyl-tRNA, causing premature termination of translation. It blocks translation by labeling and releasing elongating polypeptide chains from ribosomes and has been widely used in molecular biology research. | ||
| E2894 | Penicillin-Streptomycin | Penicillin-Streptomycin is used to prevent microbial contamination of cell culture during long-term in vitro cell culture maintenance. | ||
| S2527 | Methacycline HCl | Methacycline HCl（Rondomycin）はテトラサイクリン系Antibioticsであり、約5 μMのIC50を持つ上皮間葉転換（EMT）阻害剤でもあり、さまざまな感染症の治療に使用されます。 | ||
| S4490 | Tetracycline | Tetracycline (TC) is a broad-spectrum antibiotic that exhibits activity against a wide range of microorganisms including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, rickettsiae, and protozoan parasites. | ||
| S4783 | Benzyl isothiocyanate | Benzyl isothiocyanate (BITC, Benzoylthiocarbimide, Isothiocyanic Acid Benzoyl Ester) is an isothiocyanate originally found in cruciferous vegetables that exhibits immunomodulatory, anti-parasitic, antibiotic, antioxidative, anti-atherosclerotic, anti-angiogenic, anti-metastatic, anticancer chemotherapeutic, and chemopreventive activities. | ||
| S5199 | Oxytetracycline hydrochloride | Oxytetracycline (OTC, Oxycycin, Stevacin, Terramycin) hydrochloride is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins. | ||
| S5008 | Ciprofloxacin (CPX) hydrochloride | Ciprofloxacin (CPX) hydrochloride, a fluorinated quinolone, is a β-diketone antibiotic with a broad spectrum antibacterial activity. Ciprofloxacin is an inhibitor of bacterial DNA gyrase (a subclass of Type II topoisomerases). | ||
| S3496 | Lefamulin acetate (Xenleta) | Lefamulin acetate (Xenleta, BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, thus preventing the binding of transfer RNA for peptide transfer. | ||
| S6549 | PBTZ169 | PBTZ169 (macozinone), an antibiotic with antimycobacterial activity, is an irreversible inhibitor of DprE1. | ||
| S1611 | Cefoperazone | Cefoperazone は、rMrp2 を介した [3H]E217βG 取り込みを 199 μM の IC50 で阻害するセファロスポリン系 Antibiotics です。 | ||
| S1791 | Bacitracin Zinc | Bacitracin (Zinc Bacitracin) は、ペプチドグリカン Bacterial 細胞壁の構成要素を内膜の外側に輸送する膜キャリア分子である C55-イソプレニルピロリン酸の脱リン酸化を阻害する Antibiotics です。IC50 10 μM で Met-エンケファリンからの Tyr の切断を阻害します。 | ||
| S4974 | Oxacillin sodium | Oxacillin sodium (salt) is a narrow-spectrum β-lactam antibiotic that can be used for treatment of methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia. | ||
| E8298New | Duocarmycin SA | Duocarmycin SA is a potent antitumor antibiotic with an IC50 of 10 pM. It is an extremely potent cytotoxic agent capable of inducing a sequence-selective alkylation of duplex DNA and can be used in research treatment for glioblastoma multiforme (GBM). | ||
| S4979 | Procaine penicillin G | Penicillin G Procaine (PGP, Penicillin G Procaine, Bicillin C-R), a crystalline complex combining penicillin G with procaine, is a β-lactam antibiotic. | ||
| S4941 | Farnesol | Farnesol is a natural sesquiterpene alcohol that is potent in treating antimetabolic disorders, anti-inflammation, showing antioxidant, anticancer, and antibiotic effects. | ||
| S7784 | Fumagillin | Fumagillin(Amebacilin,NSC9168) is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis. | ||
| S4647 | Cefmenoxime hydrochloride | Cefmenoxime (SCE-1365), a potent inhibitor of Enterobacteriaceae, is a cephalosporin antibiotic that is administered intravenously or intramuscularly. | ||
| S6584 | Amdinocillin | Amdinocillin (Mecillinam, Coactin, FL 1060) is a β-lactam antibiotic with a broad spectrum of antibacterial activity. Amdinocillin is active alone against many gram-negative organisms. | ||
| E2890 | CHIR-090 | CHIR-090 is a potent and tight-binding inhibitor of the LpxC deacetylase. It also binds to E. coli LpxC with a Ki of 4.0 nM. | ||
| E0656 | 7-Methylcoumarin | 7-Methylcoumarin can inhibit the growth of S. aureus and the growth of Gram-positive bacteria within a concentration of 0.8–3.6 μg/ml, and also has a strong hepatoprotective activity. | ||
| E7524 | G-418 | G-418 (Geneticin, Antibiotic G-418) is an aminoglycoside antibiotic originally isolated from Micromonospora rhodorangea. It functions by binding to the ribosomal subunit, thereby inhibiting translational elongation and disrupting protein synthesis in both prokaryotic and eukaryotic cells, thus impairing cell growth and viability. | ||
| S4425 | Rifamycin S | Rifamycin S, a quinone and an antibiotic against Gram-positive bacteria (including MRSA), is a clinical drug used to treat tuberculosis and leprosy. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation. | ||
| S4436 | Pleuromutilin | Pleuromutilin (Drosophilin B, Mutilin 14-glycolate), the lead compound for novel antibiotics, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria. | ||
| S4488 | Delafloxacin Meglumine | Delafloxacin (ABT-492, RX-3341, WQ-3034, Baxdela) meglumine is a broad-spectrum fluoroquinolone antibiotic against multiple pathogens. | ||
| E6075New | Penicillin G benzathine tetrahydrate | Penicillin G benzathine tetrahydrate (Benzathine benzylpenicillin tetrahydrate) is a long-acting beta-lactam antibiotic effective against many bacterial infections such as impetigo. | ||
| E8298New | Duocarmycin SA | Duocarmycin SA is a potent antitumor antibiotic with an IC50 of 10 pM. It is an extremely potent cytotoxic agent capable of inducing a sequence-selective alkylation of duplex DNA and can be used in research treatment for glioblastoma multiforme (GBM). | ||
| E6061New | Cefamandole sodium | Cefamandole (sodium) is a parenteral, broad-spectrum, second-generation cephalosporin antibiotic effective against various gram-positive and gram-negative bacteria, including Neisseria, Haemophilus, and Proteus species. | ||
| E6052New | Enrofloxacin hydrochloride | Enrofloxacin hydrochloride is a fluoroquinolone antibiotic with potent activity against Mycoplasma bovis, showing an MIC₉₀ of 0.312 μg/mL. It can be used in research to study treatments for pneumonia, mastitis, arthritis, and other conditions in cattle. |
納期 国内在庫品：受注日の翌日（15時までの受注分） ＊北海道、九州、沖縄への配送は受注日より２日以上 を要する場合あり 海外在庫品：受注後１〜２週間