炭酸脱水酵素

シグナル伝達経路

研究分野

  • 阻害剤の選択性比較
  • 溶解度
カタログ番号 製品カタログ 溶解度(25°C)
水 DMSO アルコール
S1375 Dorzolamide HCl 14 mg/mL <1 mg/mL <1 mg/mL
S1438 Topiramate <1 mg/mL 68 mg/mL 68 mg/mL
S2866 U-104 <1 mg/mL 62 mg/mL <1 mg/mL
S2603 Tioxolone <1 mg/mL 34 mg/mL 34 mg/mL
S1736 Methocarbamol 2 mg/mL 48 mg/mL 48 mg/mL
S4998 2-Aminobenzenesulfonamide -1 mg/mL 34 mg/mL -1 mg/mL
S3647 Mafenide Acetate 49 mg/mL 49 mg/mL 3 mg/mL
S3697 Mafenide hydrochloride 44 mg/mL 44 mg/mL 8 mg/mL
S2177 Dichlorphenamide <1 mg/mL 61 mg/mL 33 mg/mL
S3178 Brinzolamide <1 mg/mL 77 mg/mL <1 mg/mL
S4039 Methazolamide <1 mg/mL 47 mg/mL 3 mg/mL
S4506 Acetazolamide <1 mg/mL 44 mg/mL <1 mg/mL
S4725 Benzenesulfonamide <1 mg/mL 31 mg/mL 31 mg/mL

亜型選択性的な製品

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S1375

Dorzolamide HCl

Dorzolamide HCl is a water-soluble, potent inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM, respectively, used as anti-glaucoma agent.
S1438

Topiramate

Topiramate is a mutil-targeted inhibitor, including voltage-gated sodium channel and calcium channel, AMPA/kainate receptor and carbonic anhydrase, used to treat epilepsy.
S2866

U-104

U-104 is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki of 45.1 nM and 4.5 nM, respectively, very low inhibition for CA I and CA II.
Lab Invest, 2016, 10.1038/labinvest.2016.103
Sci Rep, 2015, 5:14508
S2603

Tioxolone

Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM.
S1736

Methocarbamol

Methocarbamol is a carbonic anhydrase inhibitor, used as a central muscle relaxant to treat skeletal muscle spasms.
S4998新

2-Aminobenzenesulfonamide

2-Aminobenzenesulfonamide is an inhibitor of carbonic anhydrase IX.
S3647新

Mafenide Acetate

Mafenide Acetate is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy.
S3697新

Mafenide hydrochloride

Mafenide is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy.

S2177

Dichlorphenamide

Dichlorphenamide is a sulfonamide and a carbonic anhydrase inhibitor of the meta-Disulfamoylbenzene class.
S3178

Brinzolamide

Brinzolamide is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM.
S4039

Methazolamide

Methazolamide is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively.
S4506

Acetazolamide

Acetazolamide, a potent carbonic anhydrase (CA) inhibitor, is commonly used in clinical practice as an immediate and readily available option for acute reduction of intraocular pressure(IOP).
S4725

Benzenesulfonamide

Benzenesulfonamide ia an inhibitor of carbonic anhydrases.
Br J Pharmacol, 2016, 173(6):1018-32