Carbonic Anhydrase

亜型選択性的な製品

Carbonic Anhydrase製品

• All (18)
• Carbonic Anhydrase阻害剤 (15)
• Carbonic Anhydrase抗体(1)
• 新製品

製品コード	製品名称	製品説明	文献中Selleckの製品使用例	お客様のフィードバック
S2866	U-104	U-104 (MST-104, NSC 213841, SLC-0111, WBI-5111) is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki of 45.1 nM and 4.5 nM, respectively, very low inhibition for CA I and CA II.	Eur Thyroid J, 2025, 14(3)e250022 Nat Immunol, 2023, 24(11):1867-1878 Front Oncol, 2023, 13:1118268
S1438	Topiramate	Topiramate (MCN 4853, RWJ 17021) is a mutil-targeted inhibitor, including voltage-gated sodium channel and calcium channel, AMPA/kainate receptor and carbonic anhydrase, used to treat epilepsy.	J Headache Pain, 2025, 26(1):182 Commun Biol, 2025, 8(1):28 Cell Rep, 2022, 40(5):111153
S4506	Acetazolamide	Acetazolamide (Diamox), a potent carbonic anhydrase (CA) inhibitor, is commonly used in clinical practice as an immediate and readily available option for acute reduction of intraocular pressure(IOP).	Commun Biol, 2025, 8(1):28 Eur Thyroid J, 2025, 14(3)e250022 Cell Commun Signal, 2024, 22(1):383
S1375	Dorzolamide HCl	Dorzolamide (MK-507, L-671152) HCl is a water-soluble, potent inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM, respectively, used as anti-glaucoma agent.	Neuro Oncol, 2021, noab156 ETD, 2020, N/A
S3178	Brinzolamide	Brinzolamide (AL-4862) is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM.	Cell Rep, 2025, 44(4):115450 Commun Biol, 2025, 8(1):28 bioRxiv, 2024, 2024.03.13.584872
S3697	Mafenide hydrochloride	Mafenide is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy.	ETD, 2020, N/A
S9742	Indisulam (E7070)	Indisulam (E7070), a sulfonamide anticancer agent, is a potent carbonic anhydrase (CA) inhibitor that inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX. Indisulam suppresses the expression of cyclin E and phosphorylation of CDK2, both of which are essential for the G1 to S transition.	Nat Commun, 2025, 16(1):9754 Oncogenesis, 2024, 13(1):25 Cancer Cell, 2022, S1535-6108(22)00312-9
S4725	Benzenesulfonamide	Benzenesulfonamide (Benzenesulphonamide, Benzosulfonamide, Phenyl sulfonamide, Benzene sulfonamide) is an inhibitor of carbonic anhydrases.	Br J Pharmacol, 2016, 173(6):1018-32
S2603	Tioxolone	Tioxolone(Thioxolone) is a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM.
S1736	Methocarbamol	Methocarbamol (AHR 85) is a carbonic anhydrase inhibitor, used as a central muscle relaxant to treat skeletal muscle spasms.	Cancer Res Commun, 2025, 10.1158/2767-9764.CRC-24-0433
S2177	Dichlorphenamide	Dichlorphenamide (Diclofenamide) is a sulfonamide and a carbonic anhydrase inhibitor of the meta-Disulfamoylbenzene class.
F2607	Carbonic anhydrase 2/CA2 Antibody [C4P17]	CA2,Carbonic anhydrase 2/CA2
S4039	Methazolamide	Methazolamide (CL 8490) is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively.
S3647	Mafenide Acetate	Mafenide Acetate is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy.
E6058New	Acetazolamide sodium	Acetazolamide sodium is an inhibitor of carbonic anhydrase (CA) IX with an IC50 of 30 nM for hCA IX and also inhibits hCA II with an IC50 of 13 nM. It possesses diuretic, antihypertensive, and anti-gonococcal properties.
A2578	Girentuximab (Anti-CA9 / Carbonic anhydrase 9)	Girentuximab (Anti-CA9 / Carbonic anhydrase 9) is a chimeric monoclonal antibody that targets and binds to Carbonic Anhydrase IX (CAIX) / Carbonic Anhydrase 9 (CA9), a cell surface glycoprotein ubiquitously expressed in clear cell renal cell carcinoma (ccRCC). MW:145.5 KD.
F3479New	Carbonic Anhydrase 1/CA1 Antibody [H20K14]
S4998	2-Aminobenzenesulfonamide	2-Aminobenzenesulfonamide (Orthanilamide, O-Aminobenzenesulfonamide, O-Sulfanilamide, Benzenesulfonamide) is an inhibitor of Carbonic Anhydrase IX (CAIX) / Carbonic Anhydrase 9 (CA9).
S2866	U-104	U-104 (MST-104, NSC 213841, SLC-0111, WBI-5111) is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki of 45.1 nM and 4.5 nM, respectively, very low inhibition for CA I and CA II.	Eur Thyroid J, 2025, 14(3)e250022 Nat Immunol, 2023, 24(11):1867-1878 Front Oncol, 2023, 13:1118268
S1438	Topiramate	Topiramate (MCN 4853, RWJ 17021) is a mutil-targeted inhibitor, including voltage-gated sodium channel and calcium channel, AMPA/kainate receptor and carbonic anhydrase, used to treat epilepsy.	J Headache Pain, 2025, 26(1):182 Commun Biol, 2025, 8(1):28 Cell Rep, 2022, 40(5):111153
S4506	Acetazolamide	Acetazolamide (Diamox), a potent carbonic anhydrase (CA) inhibitor, is commonly used in clinical practice as an immediate and readily available option for acute reduction of intraocular pressure(IOP).	Commun Biol, 2025, 8(1):28 Eur Thyroid J, 2025, 14(3)e250022 Cell Commun Signal, 2024, 22(1):383
S1375	Dorzolamide HCl	Dorzolamide (MK-507, L-671152) HCl is a water-soluble, potent inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM, respectively, used as anti-glaucoma agent.	Neuro Oncol, 2021, noab156 ETD, 2020, N/A
S3178	Brinzolamide	Brinzolamide (AL-4862) is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM.	Cell Rep, 2025, 44(4):115450 Commun Biol, 2025, 8(1):28 bioRxiv, 2024, 2024.03.13.584872
S3697	Mafenide hydrochloride	Mafenide is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy.	ETD, 2020, N/A
S9742	Indisulam (E7070)	Indisulam (E7070), a sulfonamide anticancer agent, is a potent carbonic anhydrase (CA) inhibitor that inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX. Indisulam suppresses the expression of cyclin E and phosphorylation of CDK2, both of which are essential for the G1 to S transition.	Nat Commun, 2025, 16(1):9754 Oncogenesis, 2024, 13(1):25 Cancer Cell, 2022, S1535-6108(22)00312-9
S4725	Benzenesulfonamide	Benzenesulfonamide (Benzenesulphonamide, Benzosulfonamide, Phenyl sulfonamide, Benzene sulfonamide) is an inhibitor of carbonic anhydrases.	Br J Pharmacol, 2016, 173(6):1018-32
S2603	Tioxolone	Tioxolone(Thioxolone) is a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM.
S1736	Methocarbamol	Methocarbamol (AHR 85) is a carbonic anhydrase inhibitor, used as a central muscle relaxant to treat skeletal muscle spasms.	Cancer Res Commun, 2025, 10.1158/2767-9764.CRC-24-0433
S2177	Dichlorphenamide	Dichlorphenamide (Diclofenamide) is a sulfonamide and a carbonic anhydrase inhibitor of the meta-Disulfamoylbenzene class.
S4039	Methazolamide	Methazolamide (CL 8490) is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively.
S3647	Mafenide Acetate	Mafenide Acetate is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy.
E6058New	Acetazolamide sodium	Acetazolamide sodium is an inhibitor of carbonic anhydrase (CA) IX with an IC50 of 30 nM for hCA IX and also inhibits hCA II with an IC50 of 13 nM. It possesses diuretic, antihypertensive, and anti-gonococcal properties.
S4998	2-Aminobenzenesulfonamide	2-Aminobenzenesulfonamide (Orthanilamide, O-Aminobenzenesulfonamide, O-Sulfanilamide, Benzenesulfonamide) is an inhibitor of Carbonic Anhydrase IX (CAIX) / Carbonic Anhydrase 9 (CA9).
A2578	Girentuximab (Anti-CA9 / Carbonic anhydrase 9)	Girentuximab (Anti-CA9 / Carbonic anhydrase 9) is a chimeric monoclonal antibody that targets and binds to Carbonic Anhydrase IX (CAIX) / Carbonic Anhydrase 9 (CA9), a cell surface glycoprotein ubiquitously expressed in clear cell renal cell carcinoma (ccRCC). MW:145.5 KD.
E6058New	Acetazolamide sodium	Acetazolamide sodium is an inhibitor of carbonic anhydrase (CA) IX with an IC50 of 30 nM for hCA IX and also inhibits hCA II with an IC50 of 13 nM. It possesses diuretic, antihypertensive, and anti-gonococcal properties.
F3479New	Carbonic Anhydrase 1/CA1 Antibody [H20K14]

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