炭酸脱水酵素
シグナル伝達経路
研究分野
阻害剤の選択性比較
| カタログ番号 | 製品カタログ | 溶解度(25°C) | ||
|---|---|---|---|---|
| 水 | DMSO | アルコール | ||
| S1375 | Dorzolamide HCl | 14 mg/mL | <1 mg/mL | '<1 mg/mL |
| S1438 | Topiramate | <1 mg/mL | 68 mg/mL | '68 mg/mL |
| S2866 | U-104 | <1 mg/mL | 62 mg/mL | '''<1 mg/mL |
| S2603 | Tioxolone | <1 mg/mL | 34 mg/mL | 34 mg/mL |
| S1736 | Methocarbamol | 2 mg/mL | 48 mg/mL | '48 mg/mL |
| S2177 | Dichlorphenamide | <1 mg/mL | 61 mg/mL | '33 mg/mL |
| S3178 | Brinzolamide | <1 mg/mL | 77 mg/mL | <1 mg/mL |
| S4039 | Methazolamide | <1 mg/mL | 47 mg/mL | '3 mg/mL |
| S3697 | Mafenide hydrochloride | 44 mg/mL | 44 mg/mL | 8 mg/mL |
| S3647 | Mafenide Acetate | 49 mg/mL | 49 mg/mL | 3 mg/mL |
| S4506 | Acetazolamide | <1 mg/mL | 44 mg/mL | <1 mg/mL |
| S4998 | 2-Aminobenzenesulfonamide | -1 mg/mL | 34 mg/mL | '-1 mg/mL |
| S4725 | Benzenesulfonamide | <1 mg/mL | 31 mg/mL | '31 mg/mL |
亜型選択性的な製品
Carbonic Anhydrase製品
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| S1375 |
Dorzolamide HClDorzolamide (MK-507, L-671152) HCl is a water-soluble, potent inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM, respectively, used as anti-glaucoma agent. |
||
| S1438 |
TopiramateTopiramate (MCN 4853, RWJ 17021) is a mutil-targeted inhibitor, including voltage-gated sodium channel and calcium channel, AMPA/kainate receptor and carbonic anhydrase, used to treat epilepsy. |
||
| S2866 |
U-104U-104 (MST-104, NSC 213841, SLC-0111, WBI-5111) is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki of 45.1 nM and 4.5 nM, respectively, very low inhibition for CA I and CA II. |
(c-f) Effects of the CAIX inhibitor U-104 (75 μM) on cell proliferation by Pt45.P1/asTF+ cells (c, e) or Pt45.P1 cells (d, f) under advanced-stage (c, d) or early-stage conditions (e, f). At the indicated times, WST-1 uptake was measured by colorimetry. The error bars are s.e.m. * Indicates significance at P<0.05. |
|
| S2603 |
TioxoloneTioxolone is a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM. |
||
| S1736 |
MethocarbamolMethocarbamol (AHR 85) is a carbonic anhydrase inhibitor, used as a central muscle relaxant to treat skeletal muscle spasms. |
||
| S2177 |
DichlorphenamideDichlorphenamide (Diclofenamide) is a sulfonamide and a carbonic anhydrase inhibitor of the meta-Disulfamoylbenzene class. |
||
| S3178 |
BrinzolamideBrinzolamide is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM. |
||
| S4039 |
MethazolamideMethazolamide (CL 8490) is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively. |
||
| S3697 |
Mafenide hydrochlorideMafenide is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy. |
||
| S3647 |
Mafenide AcetateMafenide Acetate is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy. |
||
| S4506 |
AcetazolamideAcetazolamide, a potent carbonic anhydrase (CA) inhibitor, is commonly used in clinical practice as an immediate and readily available option for acute reduction of intraocular pressure(IOP). |
||
| S4998 |
2-Aminobenzenesulfonamide2-Aminobenzenesulfonamide (Orthanilamide, O-Aminobenzenesulfonamide, O-Sulfanilamide, Benzenesulfonamide) is an inhibitor of carbonic anhydrase IX. |
||
| S4725 |
BenzenesulfonamideBenzenesulfonamide (Benzenesulphonamide, Benzosulfonamide, Phenyl sulfonamide, Benzene sulfonamide) ia an inhibitor of carbonic anhydrases. |
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| S1375 |
Dorzolamide HClDorzolamide (MK-507, L-671152) HCl is a water-soluble, potent inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM, respectively, used as anti-glaucoma agent. |
||
| S1438 |
TopiramateTopiramate (MCN 4853, RWJ 17021) is a mutil-targeted inhibitor, including voltage-gated sodium channel and calcium channel, AMPA/kainate receptor and carbonic anhydrase, used to treat epilepsy. |
||
| S2866 |
U-104U-104 (MST-104, NSC 213841, SLC-0111, WBI-5111) is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki of 45.1 nM and 4.5 nM, respectively, very low inhibition for CA I and CA II. |
(c-f) Effects of the CAIX inhibitor U-104 (75 μM) on cell proliferation by Pt45.P1/asTF+ cells (c, e) or Pt45.P1 cells (d, f) under advanced-stage (c, d) or early-stage conditions (e, f). At the indicated times, WST-1 uptake was measured by colorimetry. The error bars are s.e.m. * Indicates significance at P<0.05. |
|
| S2603 |
TioxoloneTioxolone is a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM. |
||
| S1736 |
MethocarbamolMethocarbamol (AHR 85) is a carbonic anhydrase inhibitor, used as a central muscle relaxant to treat skeletal muscle spasms. |
||
| S2177 |
DichlorphenamideDichlorphenamide (Diclofenamide) is a sulfonamide and a carbonic anhydrase inhibitor of the meta-Disulfamoylbenzene class. |
||
| S3178 |
BrinzolamideBrinzolamide is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM. |
||
| S4039 |
MethazolamideMethazolamide (CL 8490) is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively. |
||
| S3697 |
Mafenide hydrochlorideMafenide is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy. |
||
| S3647 |
Mafenide AcetateMafenide Acetate is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy. |
||
| S4506 |
AcetazolamideAcetazolamide, a potent carbonic anhydrase (CA) inhibitor, is commonly used in clinical practice as an immediate and readily available option for acute reduction of intraocular pressure(IOP). |
||
| S4998 |
2-Aminobenzenesulfonamide2-Aminobenzenesulfonamide (Orthanilamide, O-Aminobenzenesulfonamide, O-Sulfanilamide, Benzenesulfonamide) is an inhibitor of carbonic anhydrase IX. |
||
| S4725 |
BenzenesulfonamideBenzenesulfonamide (Benzenesulphonamide, Benzosulfonamide, Phenyl sulfonamide, Benzene sulfonamide) ia an inhibitor of carbonic anhydrases. |
