Chloride Channel

  • 阻害剤の選択性比較
  • 溶解度
カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S8279 Shikonin <1 mg/mL 57 mg/mL 23 mg/mL
S3807 Dehydroandrographolide -1 mg/mL 66 mg/mL -1 mg/mL
S1675 Lubiprostone <1 mg/mL 78 mg/mL 78 mg/mL
S1351 Ivermectin <1 mg/mL 100 mg/mL 28 mg/mL
製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S8279

Shikonin

Shikonin, a potent and specific Pyruvate kinase M2 (PKM2) inhibitor, is a major component of zicao (purple gromwell, the dried root of Lithospermum erythrorhizon), a Chinese herbal medicine with various biological activities. It is also an inhibitor of TMEM16A chloride channel activity using cell-based fluorescent-quenching assay.

S3807

Dehydroandrographolide

Dehydroandrographolide, isolated from Andrographis paniculata (Burm. F.) Nees (Chuan-xin-lian), is a novel TMEM16A inhibitor and possesses multiple pharmacological activities, including anti-inflammation, anti-cancer, anti-bacterial, anti-virus and anti-hepatitis activity.

S1675

Lubiprostone

Lubiprostone is an activator of ClC-2 chloride channels, used in the management of idiopathic chronic constipation.

S1351

Ivermectin

Ivermectin is a glutamate-gated chloride channel (GluCls) activator, used as a broad-spectrum antiparasitic drug.

Tags: Chloride Channel inhibitor | Chloride Channel activator | Chloride Channel blocker