Chloride Channel

阻害剤の選択性比較

カタログ番号	製品カタログ	溶解度(25°C)
カタログ番号	製品カタログ	水	DMSO	アルコール
S1698	Torsemide	<1 mg/mL	3 mg/mL	<1 mg/mL
S8279	Shikonin	<1 mg/mL	57 mg/mL	23 mg/mL
S3807	Dehydroandrographolide	-1 mg/mL	66 mg/mL	-1 mg/mL
S1675	Lubiprostone	<1 mg/mL	78 mg/mL	78 mg/mL
S1351	Ivermectin	<1 mg/mL	100 mg/mL	28 mg/mL

Chloride Channel製品

All (5) Chloride Channel阻害剤(3) Chloride Channel活性剤(2)

製品コード	製品説明	文献中Selleckの製品使用例
S1698	Torsemide Torsemide is a pyridyl sulfonylurea with a chemical structure between that of traditional loop diuretics and Cl- channel blockers, used to treat hypertension.
S8279	Shikonin Shikonin, a potent and specific Pyruvate kinase M2 (PKM2) inhibitor, is a major component of zicao (purple gromwell, the dried root of Lithospermum erythrorhizon), a Chinese herbal medicine with various biological activities. It is also an inhibitor of TMEM16A chloride channel activity using cell-based fluorescent-quenching assay.	Mol Med Rep, 2018, 18(4):3882-3890
S3807	Dehydroandrographolide Dehydroandrographolide, isolated from Andrographis paniculata (Burm. F.) Nees (Chuan-xin-lian), is a novel TMEM16A inhibitor and possesses multiple pharmacological activities, including anti-inflammation, anti-cancer, anti-bacterial, anti-virus and anti-hepatitis activity.
S1675	Lubiprostone Lubiprostone is an activator of ClC-2 chloride channels, used in the management of idiopathic chronic constipation.
S1351	Ivermectin Ivermectin is a glutamate-gated chloride channel (GluCls) activator, used as a broad-spectrum antiparasitic drug.	Cell Death Dis, 2019, 10(2):118

製品コード

製品説明

文献中Selleckの製品使用例

お客様のフィードバック

S1698

Torsemide

Torsemide is a pyridyl sulfonylurea with a chemical structure between that of traditional loop diuretics and Cl- channel blockers, used to treat hypertension.

S8279

Shikonin, a potent and specific Pyruvate kinase M2 (PKM2) inhibitor, is a major component of zicao (purple gromwell, the dried root of Lithospermum erythrorhizon), a Chinese herbal medicine with various biological activities. It is also an inhibitor of TMEM16A chloride channel activity using cell-based fluorescent-quenching assay.

Mol Med Rep, 2018, 18(4):3882-3890

S3807

Dehydroandrographolide

Dehydroandrographolide, isolated from Andrographis paniculata (Burm. F.) Nees (Chuan-xin-lian), is a novel TMEM16A inhibitor and possesses multiple pharmacological activities, including anti-inflammation, anti-cancer, anti-bacterial, anti-virus and anti-hepatitis activity.

製品コード	製品説明	文献中Selleckの製品使用例	お客様のフィードバック
S1675	Lubiprostone Lubiprostone is an activator of ClC-2 chloride channels, used in the management of idiopathic chronic constipation.
S1351	Ivermectin Ivermectin is a glutamate-gated chloride channel (GluCls) activator, used as a broad-spectrum antiparasitic drug.	Cell Death Dis, 2019, 10(2):118

製品コード

製品説明

文献中Selleckの製品使用例

お客様のフィードバック

S1675