gp120/CD4

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
水 DMSO アルコール
S2632 BMS-378806 <1 mg/mL 81 mg/mL 3 mg/mL
S7220 Fostemsavir <1 mg/mL 100 mg/mL '''''''<1 mg/mL
S7487 YYA-021 <1 mg/mL 0.01 mg/mL <1 mg/mL
A2101 Anti-mouse CD4-InVivo 150 kDa mg/mL protein A mg/mL 0.2 μM filtered mg/mL

gp120/CD4製品

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S2632

BMS-378806

BMS-378806 (BMS 806) selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus.
J Virol, 2020, 10.1128/JVI.00148-20
Traffic, 2017, 18(6):392-410
S7220

Fostemsavir

Fostemsavir (BMS-663068, Rukobia), the phosphonooxymethyl prodrug of BMS626529, is an attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells with EC50 of < 10 nM.
S7487

YYA-021

YYA-021 is a CD4-mimic HIV entry inhibitor, competitively inhibiting the interaction between gp120 and CD4.
A2101

Anti-mouse CD4-InVivo

Anti-mouse CD4 antibody reacts with mouse CD4, which is a 55 kDa cell surface type I membrane glycoprotein. CD4 is a co-receptor of the T cell receptor (TCR) and assists the latter in communicating with antigen-presenting cells.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S2632

BMS-378806

BMS-378806 (BMS 806) selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus.
J Virol, 2020, 10.1128/JVI.00148-20
Traffic, 2017, 18(6):392-410
S7220

Fostemsavir

Fostemsavir (BMS-663068, Rukobia), the phosphonooxymethyl prodrug of BMS626529, is an attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells with EC50 of < 10 nM.
S7487

YYA-021

YYA-021 is a CD4-mimic HIV entry inhibitor, competitively inhibiting the interaction between gp120 and CD4.
製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
A2101

Anti-mouse CD4-InVivo

Anti-mouse CD4 antibody reacts with mouse CD4, which is a 55 kDa cell surface type I membrane glycoprotein. CD4 is a co-receptor of the T cell receptor (TCR) and assists the latter in communicating with antigen-presenting cells.