GTPase

GTPase製品

All (5)
GTPase阻害剤 (5)
新製品

製品コード	製品名称	製品説明	文献中Selleckの製品使用例
S7606	RBC8	RBC8 is a selective inhibitor of the GTPases RalA and RalB by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases Ras and RhoA.	Cell Res, 2025, 10.1038/s41422-025-01085-9 J Exp Clin Cancer Res, 2022, 41(1):301 Haematologica, 2019, 10.3324/haematol.2019.223024
S2901	CCG 50014	CCG 50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM.	Mol Pharmacol, 2018, 93(1):25-35
S7607	BQU57	BQU57, a derivative of RBC8, is a selective GTPase Ral inhibitor relative to the GTPases Ras and RhoA.	J Adv Res, 2024, S2090-1232(24)00171-1 PLoS One, 2019, 14(4):e0214764
E1047	NAV-2729	NAV-2729, an inhibitor of Arf6 activation which directly binds to Arf6, also inhibits all Arf guanine nucleotide exchange factors (ArfGEFs) with a strongest effect against BRAG2 and Arf1 .
E4716	QS11	QS11 acts as an inhibitor of ARFGAP1 (ADP-ribosylation factor GTPase-activating protein 1), with an EC50 of 1.5 μM. QS11 regulates Wnt/β-catenin signaling by interacting with ARF GTPase-activating protein 1 (ARFGAP1) and influences protein trafficking. Additionally, QS11 suppresses the migration of breast cancer cells that overexpress ARFGAP1.
S7606	RBC8	RBC8 is a selective inhibitor of the GTPases RalA and RalB by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases Ras and RhoA.	Cell Res, 2025, 10.1038/s41422-025-01085-9 J Exp Clin Cancer Res, 2022, 41(1):301 Haematologica, 2019, 10.3324/haematol.2019.223024
S2901	CCG 50014	CCG 50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM.	Mol Pharmacol, 2018, 93(1):25-35
S7607	BQU57	BQU57, a derivative of RBC8, is a selective GTPase Ral inhibitor relative to the GTPases Ras and RhoA.	J Adv Res, 2024, S2090-1232(24)00171-1 PLoS One, 2019, 14(4):e0214764
E1047	NAV-2729	NAV-2729, an inhibitor of Arf6 activation which directly binds to Arf6, also inhibits all Arf guanine nucleotide exchange factors (ArfGEFs) with a strongest effect against BRAG2 and Arf1 .
E4716	QS11	QS11 acts as an inhibitor of ARFGAP1 (ADP-ribosylation factor GTPase-activating protein 1), with an EC50 of 1.5 μM. QS11 regulates Wnt/β-catenin signaling by interacting with ARF GTPase-activating protein 1 (ARFGAP1) and influences protein trafficking. Additionally, QS11 suppresses the migration of breast cancer cells that overexpress ARFGAP1.