HBV

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S1704 Emtricitabine (BW 1592) 49 mg/mL 49 mg/mL ''''9 mg/mL
S0285 Bay 41-4109 racemate ˂1 mg/mL 79 mg/mL ''11 mg/mL
S0038 AB-423 ˂1 mg/mL 77 mg/mL '77 mg/mL
S5979 2',3'-Dideoxyadenosine 47 mg/mL 47 mg/mL ''''<1 mg/mL
E0094 Morphothiadin <1 mg/mL 100 mg/mL 12 mg/mL
S8627 OSS_128167 <1 mg/mL 73 mg/mL '<1 mg/mL
S6729 Besifovir 60 mg/mL 60 mg/mL '2 mg/mL
S0796 JNJ-632 <1 mg/mL 76 mg/mL ''''76 mg/mL

HBV製品

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S1704

Emtricitabine (BW 1592)

Emtricitabine (BW1592, FTC) is a new nucleoside agent that has activity against both human immunodeficiency virus (HIV) and hepatitis B virus. It is a reverse transcriptase inhibitor. Intracellular half-life is 39 h.

S0285

Bay 41-4109 racemate

BAY 41-4109 racemate (BAY41-4109 Racemic) is a mixture of R-isomer of BAY 41-4109 and S-isomer of BAY 41-4109. BAY 41-4109 an antiviral compound that inhibits human hepatitis B virus (HBV) with IC50 of 53 nM.

S0038

AB-423

AB-423, a member of the sulfamoylbenzamide (SBA) class of hepatitis B virus (HBV) capsid inhibitors, shows potent inhibition of HBV replication with EC50 of 0.08 μM - 0.27 μM and EC90 of 0.33 μM - 1.32 μM in cells. Phase 1.

S5979

2',3'-Dideoxyadenosine

2',3'-Dideoxyadenosine (ddA, ddAdo) is an anti-human immunodeficiency virus agent against human immunodeficiency virus (HIV) and human hepatitis B virus (HBV) replication.

E0094

Morphothiadin

Morphothiadin (GLS4) is a potent inhibitor on the replication of both wild-type and adefovir-resistant Hepatitis B virus (HBV) with an IC50 of 12 nM. Morphothiadin (GLS4), a nucleoside analogs that target the virus polymerase, can block the HBV replication cycle and HBV-associated chronic liver diseases.

S8627

OSS_128167

OSS_128167 (SIRT6-IN-1) is a specific SIRT6 inhibitor with IC50 values of 89, 1578 and 751 μM for SIRT6, SIRT1 and SIRT2, respectively. OSS_128167 has anti-viral effect in HBV transcription and replication.

S6729

Besifovir

Besifovir is novel and potent acyclic nucleotide phosphonate used to treat hepatitis B virus (HBV) infection.

S0796

JNJ-632

JNJ-632 is a potent hepatitis B virus (HBV) capsid assembly modulator (CAM) with mean EC50 of 121 nM in HepG2.2.15 cells.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S1704

Emtricitabine (BW 1592)

Emtricitabine (BW1592, FTC) is a new nucleoside agent that has activity against both human immunodeficiency virus (HIV) and hepatitis B virus. It is a reverse transcriptase inhibitor. Intracellular half-life is 39 h.

S0285

Bay 41-4109 racemate

BAY 41-4109 racemate (BAY41-4109 Racemic) is a mixture of R-isomer of BAY 41-4109 and S-isomer of BAY 41-4109. BAY 41-4109 an antiviral compound that inhibits human hepatitis B virus (HBV) with IC50 of 53 nM.

S0038

AB-423

AB-423, a member of the sulfamoylbenzamide (SBA) class of hepatitis B virus (HBV) capsid inhibitors, shows potent inhibition of HBV replication with EC50 of 0.08 μM - 0.27 μM and EC90 of 0.33 μM - 1.32 μM in cells. Phase 1.

S5979

2',3'-Dideoxyadenosine

2',3'-Dideoxyadenosine (ddA, ddAdo) is an anti-human immunodeficiency virus agent against human immunodeficiency virus (HIV) and human hepatitis B virus (HBV) replication.

E0094

Morphothiadin

Morphothiadin (GLS4) is a potent inhibitor on the replication of both wild-type and adefovir-resistant Hepatitis B virus (HBV) with an IC50 of 12 nM. Morphothiadin (GLS4), a nucleoside analogs that target the virus polymerase, can block the HBV replication cycle and HBV-associated chronic liver diseases.

S8627

OSS_128167

OSS_128167 (SIRT6-IN-1) is a specific SIRT6 inhibitor with IC50 values of 89, 1578 and 751 μM for SIRT6, SIRT1 and SIRT2, respectively. OSS_128167 has anti-viral effect in HBV transcription and replication.

S6729

Besifovir

Besifovir is novel and potent acyclic nucleotide phosphonate used to treat hepatitis B virus (HBV) infection.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S0796

JNJ-632

JNJ-632 is a potent hepatitis B virus (HBV) capsid assembly modulator (CAM) with mean EC50 of 121 nM in HepG2.2.15 cells.

Tags: HBV inhibitor|HBV agonist|HBV activator|HBV inducer|HBV antagonist|HBV signaling pathway|HBV assay kit