MLL

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S7265 MM-102 100 mg/mL 100 mg/mL 100 mg/mL
S7817 MI-503 <1 mg/mL 100 mg/mL 15 mg/mL
S7619 MI-3 (Menin-MLL Inhibitor) <1 mg/mL 19 mg/mL 19 mg/mL
S7618 MI-2 (Menin-MLL Inhibitor) <1 mg/mL 75 mg/mL 75 mg/mL

MLL製品

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S7265

MM-102

MM-102 is a high-affinity peptidomimetic MLL1 inhibitor with IC50 of 0.4 μM in a cell-free assay.

S7817

MI-503

MI-503 is a potent and selective Menin-MLL inhibitor with IC50 of 14.7 nM. It shows pronounced growth suppressive activity in a panel of human MLL leukemia cell lines(GI50 at 250 nM-570 nM range), but only a minimal effect in human leukemia cell lines without MLL translocations.

S7619

MI-3 (Menin-MLL Inhibitor)

MI-3 (Menin-MLL Inhibitor) is a potent menin-MLL interaction inhibitor with IC50 of 648 nM.

S7618

MI-2 (Menin-MLL Inhibitor)

MI-2 (Menin-MLL Inhibitor) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S7265

MM-102

MM-102 is a high-affinity peptidomimetic MLL1 inhibitor with IC50 of 0.4 μM in a cell-free assay.

S7817

MI-503

MI-503 is a potent and selective Menin-MLL inhibitor with IC50 of 14.7 nM. It shows pronounced growth suppressive activity in a panel of human MLL leukemia cell lines(GI50 at 250 nM-570 nM range), but only a minimal effect in human leukemia cell lines without MLL translocations.

S7619

MI-3 (Menin-MLL Inhibitor)

MI-3 (Menin-MLL Inhibitor) is a potent menin-MLL interaction inhibitor with IC50 of 648 nM.

S7618

MI-2 (Menin-MLL Inhibitor)

MI-2 (Menin-MLL Inhibitor) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.

Tags: MLL inhibitor | MLL modulator | MLL regulation| MLL interaction | MLL inhibition