PKD

PKD製品

All (4)
PKD阻害剤 (4)
新製品

製品コード	製品名称	製品説明	文献中Selleckの製品使用例
S7188	CID755673	CID755673 is a cell-active pan-PKD1/2/3 inhibitor with IC50 of 180 nM, 280nM, and 227 nM, respectively, about 200-fold selectivity over other CAMKs.	Nat Commun, 2023, 14(1):3543 Oncogene, 2023, 42(39):2878-2891 Oncogene, 2023, 10.1038/s41388-023-02809-0
S8366	CRT0066101 dihydrochloride	CRT0066101 dihydrochloride is a small molecule PKD family specific inhibitor which specifically blocks PKD1/2 activity and does not suppress PKCα/PKCβ/PKCε activity in multiple.	Cell Rep, 2023, 42(9):113035 Cells, 2023, 12(2)212 NAR Cancer, 2023, 5(2):zcad027
S5792	CID 2011756	CID 2011756 is an inhibitor of protein kinase D (PKD) with IC50 values of 3.2, 0.6, and 0.7 μM for PKD1, PKD2, and PKD3, respectively.
S2642	1-Naphthyl PP1(1-NA-PP1)	1-Naphthyl PP1(1-NA-PP 1) is a highly selective and potent pan-PKD inhibitor with IC50 of 154.6 nM,133.4 nM and 109.4 nM for PKD1, PKD2 and PKD3, respectively. 1-Naphthyl PP1 is a selective inhibitor of Src family kinases (v-Src, c-Fyn) and the tyrosine kinase c-Abl with IC50 of 1.0 μM, 0.6 μM, 0.6 μM, 18 μM and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II, respectively.
S7188	CID755673	CID755673 is a cell-active pan-PKD1/2/3 inhibitor with IC50 of 180 nM, 280nM, and 227 nM, respectively, about 200-fold selectivity over other CAMKs.	Nat Commun, 2023, 14(1):3543 Oncogene, 2023, 42(39):2878-2891 Oncogene, 2023, 10.1038/s41388-023-02809-0
S8366	CRT0066101 dihydrochloride	CRT0066101 dihydrochloride is a small molecule PKD family specific inhibitor which specifically blocks PKD1/2 activity and does not suppress PKCα/PKCβ/PKCε activity in multiple.	Cell Rep, 2023, 42(9):113035 Cells, 2023, 12(2)212 NAR Cancer, 2023, 5(2):zcad027
S5792	CID 2011756	CID 2011756 is an inhibitor of protein kinase D (PKD) with IC50 values of 3.2, 0.6, and 0.7 μM for PKD1, PKD2, and PKD3, respectively.
S2642	1-Naphthyl PP1(1-NA-PP1)	1-Naphthyl PP1(1-NA-PP 1) is a highly selective and potent pan-PKD inhibitor with IC50 of 154.6 nM,133.4 nM and 109.4 nM for PKD1, PKD2 and PKD3, respectively. 1-Naphthyl PP1 is a selective inhibitor of Src family kinases (v-Src, c-Fyn) and the tyrosine kinase c-Abl with IC50 of 1.0 μM, 0.6 μM, 0.6 μM, 18 μM and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II, respectively.

PKD阻害剤の選択性比較