PP2A

PP2A阻害剤の選択性比較

PP2A製品

  • All (4)
  • PP2A阻害剤 (3)
  • PP2A活性剤(1)
  • 新製品
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S0308 AMZ30 AMZ30 (ML136, CS-2122) is a selective and covalent inhibitor of protein phosphatase methylesterase-1(PME-1) with IC50 of 0.60 μM. AMZ30 reduces the demethylated form of PP2A in living cells.
S7537 LB-100 LB-100 is a water soluble protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells.
J Neuroinflammation, 2022, 19(1):177
Sci Signal, 2022, 15(716):eabi7400
Mol Cell, 2021, S1097-2765(21)00624-9
S8248 IQ-1 IQ-1 enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation, Maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells and prevents PP2A/Nkd interaction.
Neoplasia, 2020, 23(1):1-11
Cell Mol Life Sci, 2019, 76(14):2817-2832
Front Genet, 2018, 9:746
S8774 DT-061 (SMAP) DT-061 (SMAP) is a bioavailable PP2A activator. It decreases cell viability in HCC827 and HCC3255 cell lines, with IC50 values of 14.3 μM and 12.4 μM respectively.
Development, 2021, dev.198838
Research Square, 2021, 10.21203/rs.3.rs-362391/v1
S0308 AMZ30 AMZ30 (ML136, CS-2122) is a selective and covalent inhibitor of protein phosphatase methylesterase-1(PME-1) with IC50 of 0.60 μM. AMZ30 reduces the demethylated form of PP2A in living cells.
S7537 LB-100 LB-100 is a water soluble protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells.
J Neuroinflammation, 2022, 19(1):177
Sci Signal, 2022, 15(716):eabi7400
Mol Cell, 2021, S1097-2765(21)00624-9
S8248 IQ-1 IQ-1 enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation, Maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells and prevents PP2A/Nkd interaction.
Neoplasia, 2020, 23(1):1-11
Cell Mol Life Sci, 2019, 76(14):2817-2832
Front Genet, 2018, 9:746
S8774 DT-061 (SMAP) DT-061 (SMAP) is a bioavailable PP2A activator. It decreases cell viability in HCC827 and HCC3255 cell lines, with IC50 values of 14.3 μM and 12.4 μM respectively.
Development, 2021, dev.198838
Research Square, 2021, 10.21203/rs.3.rs-362391/v1
Tags: PP2A inhibitor|PP2A agonist|PP2A activator|PP2A inducer|PP2A antagonist|PP2A signaling pathway|PP2A assay kit