Tisotumab vedotin

Tisotumab vedotin (TF-011-MMAE, HuMax-TF-ADC) is an antibody-drug conjugate (ADC) composed of a fully human monoclonal antibody to tissue factor III (thromboplastin) also known as CD142, conjugated to Monomethyl Auristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinylp-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Tisotumab vedotin has the potential for use in research of solid tumors mainly in cervical cancer.

CAS No. 1418731-10-8

サイズ	価格(税別)	在庫状況
1mg	JPY 145500	国内在庫あり
1mg*5	JPY 445500	お問い合わせ

代表番号: 045-509-1970\|電子メール：[email protected] よく尋ねられる質問

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質量管理及び製品安全説明書

現在のバッチを見る： D405101 純度： 98% タンパク質濃度： 9.88mg/ml 内毒素：＜1EU/mg

98

CD markers阻害剤の選択性比較

生物活性

製品説明	Tisotumab vedotin (TF-011-MMAE, HuMax-TF-ADC) is an antibody-drug conjugate (ADC) composed of a fully human monoclonal antibody to tissue factor III (thromboplastin) also known as CD142, conjugated to Monomethyl Auristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinylp-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Tisotumab vedotin has the potential for use in research of solid tumors mainly in cervical cancer.

製品説明

Tisotumab vedotin (TF-011-MMAE, HuMax-TF-ADC) is an antibody-drug conjugate (ADC) composed of a fully human monoclonal antibody to tissue factor III (thromboplastin) also known as CD142, conjugated to Monomethyl Auristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinylp-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Tisotumab vedotin has the potential for use in research of solid tumors mainly in cervical cancer.

参考
[1] Heitz N, et al. Ann Pharmacother. 2023 May;57(5):585-596. [2] Gibiansky L, et al. CPT Pharmacometrics Syst Pharmacol. 2022 Oct;11(10):1358-1370.

参考

製品説明

CAS No.	1418731-10-8
Formulation	1xPBS
DAR	4.2
ADC antiody	Tisotumab
ADC cytotoxin	MMAE
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.
Shipping	Shipped under low temperature conditions

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質量管理及び製品安全説明書

CD markers阻害剤の選択性比較

生物活性

製品説明

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