• ET-A
  • ET-B

ET-B 拮抗剤

製品コード 製品名 製品説明 Selective / Pan IC50 / Ki
S3051 Bosentan Hydrate Bosentan (Ro 47-0203) is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively. Pan ET-B, Ki: 95 nM
S8051 Macitentan (ACT 064992) Macitentan (ACT 064992) is an orally active, non-peptide, dual ETA/ETB (endothelin) receptor antagonist with IC50 of 0.5 nM/391 nM. Pan ET-B, IC50: 391 nM