- Proteasome
- 20S proteasome
Proteasome 選択性阻害剤
製品コード | 製品名 | 製品説明 | Selective / Pan | IC50 / Ki |
---|---|---|---|---|
S2853 | Carfilzomib (PR-171) | Carfilzomib (PR-171) is an irreversible proteasome inhibitor with IC50 of <5 nM, displayed preferential in vitro inhibitory potency against the ChT-L activity in the β5 subunit, but little or no effect on the PGPH and T-L activities. |
Selective | Proteasome, IC50: 5 nM |
S2619 | MG-132 | MG-132 is an inhibitor of proteasome with IC50 of 100 nM, and also inhibits calpain with IC50 of 1.2 μM. |
Selective | Proteasome, IC50: 100 nM |