ホームページ Immunology & Inflammation TLR TLR1 阻害剤
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TLR1 阻害剤

製品コード 製品名 製品説明 Selective / Pan IC50 / Ki
S8677 Cu-CPT22 CU-CPT22 shows dose-dependent inhibitory effects blocking Pam3CSK4-induced TLR1/2 activation with an IC50 of 0.58 ± 0.09 µM while no significant inhibition to TLR2/6. It demonstrates minimal non-specific inhibition against a panel of 10 representative kinases (PDGFRB, MET, DDR2, SRC, MAPK1, PAK1, AKT1, PKC-γ, CAMK1, and PLK4). Pan TLR1/2, IC50: 0.58 μM