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Specific Compounds Quantities 96 or 384 well Plate Map Dry/solid or DMSO solution

抗体

製品コード	製品名	製品説明	Selective / Pan	IC50 / Ki
S3245	Nodakenetin	Nodakenetin (NANI), a plant-derived coumarin isolated from Angelica decursiva, inhibits α-glucosidase, PTP1B, rat lens aldose reductase (RLAR), AChE, BChE, and β-site amyloid precursor protein cleaving enzyme 1 (BACE1). Nodakenetin alters the protein expression of Bax and Bcl-2, and prompts mitochondrial apoptosis. Nodakenetin exhibits anti-tumor activity.	Selective
S3839	1-Deoxynojirimycin	1-Deoxynojirimycin (duvoglustat, moranolin) is a potent α-glucosidase inhibitor and most commonly found in mulberry leaves. It has therapeutic potency against diabetes mellitus.	Selective
S6921	Dorzagliatin	Dorzagliatin (HMS-5552, RO-5305552, Sinogliatin) is a dual-acting glucokinase (GK) activator that improves glycaemic control and pancreatic β-cell function in patients with type 2 diabetes.	Selective
S2155	LY2608204	LY2608204 activates glucokinase (GK) with EC50 of 42 nM. Phase 2.	Selective	glucokinase , EC50: 42 nM
S3527	AM2394	AM-2394 is a structurally distinct glucokinase activator (GKA), activates glucokinase (GK) with an EC50 of 60 nM.	Selective	GK, EC50: 60 nM
S0553	Butyl isobutyl phthalate	Butyl isobutyl phthalate (BIP), isolated from the rhizoid of Laminaria japonica, is a non-competitive inhibitor of α-glucosidase with IC50 of 38 μM. Butyl isobutyl phthalate displays a significant hypoglycemic effect and has the potential for diabetes treatment.	Selective	α-glucosidase, IC50: 38 μM

hexokinase 選択性 阻害剤 | 活性剤 | モジュレータ

hexokinase 選択性阻害剤 | 活性剤 | モジュレータ