トロンビン
阻害剤の選択性比較
| カタログ番号 | 製品カタログ | 溶解度(25°C) | ||
|---|---|---|---|---|
| 水 | DMSO | アルコール | ||
| S2196 | Dabigatran (BIBR 953) | <1 mg/mL | 0.5 mg/mL | 0.01 mg/mL |
| S2154 | Dabigatran Etexilate | <1 mg/mL | 126 mg/mL | 12 mg/mL |
| S2069 | Argatroban | <1 mg/mL | 9 mg/mL | 6 mg/mL |
| S5074 | Argatroban hydrate|Argipidine | <1 mg/mL | 100 mg/mL | 40 mg/mL |
| S1346 | Heparin sodium | 100 mg/mL | <1 mg/mL | <1 mg/mL |
Thrombin製品
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| S2196 |
Dabigatran (BIBR 953)Dabigatran (BIBR 953) is a potent nonpeptide thrombin inhibitor with an IC50 of 9.3 nM in a cell-free assay. |
|
|
| S2154 |
Dabigatran EtexilateDabigatran Etexilate is the prodrug of dabigatran, a potent, nonpeptidic small molecule that specifically and reversibly inhibits both free and clot-bound thrombin by binding to the active site of the thrombin molecule. |
|
|
| S2069 |
ArgatrobanArgatroban is a potent and selective synthetic thrombin inhibitor with Ki ranging from 5 nM to 39 nM, used as an anticoagulant. |
||
| S4545新 |
WarfarinWarfarin is one of the most widely used anticoagulant drugs worldwide, used in the prevention of thrombosis and thromboembolism, the formation of blood clots in the blood vessels and their migration elsewhere in the body. |
||
| S5074 |
Argatroban hydrate|ArgipidineArgatroban is a direct, selective thrombin inhibitor with anticoagulant effects. |
||
| S1346 |
Heparin sodiumHeparin sodium, a sulfated polysaccharide belonging to the family of glycosaminoglycans, has numerous important biological activities associated with its interaction with diverse proteins, used as an anticoagulant. |
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| S2196 |
Dabigatran (BIBR 953)Dabigatran (BIBR 953) is a potent nonpeptide thrombin inhibitor with an IC50 of 9.3 nM in a cell-free assay. |
|
|
| S2154 |
Dabigatran EtexilateDabigatran Etexilate is the prodrug of dabigatran, a potent, nonpeptidic small molecule that specifically and reversibly inhibits both free and clot-bound thrombin by binding to the active site of the thrombin molecule. |
|
|
| S2069 |
ArgatrobanArgatroban is a potent and selective synthetic thrombin inhibitor with Ki ranging from 5 nM to 39 nM, used as an anticoagulant. |
||
| S4545新 |
WarfarinWarfarin is one of the most widely used anticoagulant drugs worldwide, used in the prevention of thrombosis and thromboembolism, the formation of blood clots in the blood vessels and their migration elsewhere in the body. |
||
| S5074 |
Argatroban hydrate|ArgipidineArgatroban is a direct, selective thrombin inhibitor with anticoagulant effects. |
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| S1346 |
Heparin sodiumHeparin sodium, a sulfated polysaccharide belonging to the family of glycosaminoglycans, has numerous important biological activities associated with its interaction with diverse proteins, used as an anticoagulant. |
2019, 10.1007/s13238-019-0610-7 2019, 54(3):1061-1070 |
