トロンビン
阻害剤の選択性比較
| カタログ番号 | 製品カタログ | 溶解度(25°C) | ||
|---|---|---|---|---|
| 水 | DMSO | アルコール | ||
| S2196 | Dabigatran (BIBR 953) | <1 mg/mL | 0.5 mg/mL | '0.01 mg/mL |
| S2154 | Dabigatran (BIBR-1048) etexilate | <1 mg/mL | 126 mg/mL | '12 mg/mL |
| S1346 | Heparin sodium | 100 mg/mL | <1 mg/mL | <1 mg/mL |
| S2069 | Argatroban (MCI-9038) | <1 mg/mL | 9 mg/mL | '6 mg/mL |
| S5960 | Dabigatran etexilate mesylate | <1 mg/mL | 100 mg/mL | '''20 mg/mL |
| S5074 | Argatroban Monohydrate | <1 mg/mL | 100 mg/mL | 40 mg/mL |
Thrombin製品
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| S2196 |
Dabigatran (BIBR 953)Dabigatran (BIBR 953) is a potent nonpeptide thrombin inhibitor with an IC50 of 9.3 nM in a cell-free assay. |
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| S2154 |
Dabigatran (BIBR-1048) etexilateDabigatran Etexilate (BIBR-1048) is the prodrug of dabigatran, a potent, nonpeptidic small molecule that specifically and reversibly inhibits both free and clot-bound thrombin by binding to the active site of the thrombin molecule. |
|
|
| S1346 |
Heparin sodiumHeparin sodium, a sulfated polysaccharide belonging to the family of glycosaminoglycans, has numerous important biological activities associated with its interaction with diverse proteins. Heparin is used as an anticoagulant primarily through its interaction with AT III by enhancing AT-IIImediated inhibition of blood coagulation factors, including thrombin and factor Xa. Heparin prevents the induction of autophagy. |
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| S2069 |
Argatroban (MCI-9038)Argatroban (MCI-9038) is a potent and selective synthetic thrombin inhibitor with Ki ranging from 5 nM to 39 nM, used as an anticoagulant. |
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| S4545 |
WarfarinWarfarin (Athrombine K, Coumadin, Coumafene, WARF 42, Zoocoumarin) is one of the most widely used anticoagulant drugs worldwide, used in the prevention of thrombosis and thromboembolism, the formation of blood clots in the blood vessels and their migration elsewhere in the body. |
||
| S5960 |
Dabigatran etexilate mesylateDabigatran etexilate mesylate (Pradaxa, BIBR 1048MS, Dabigatran etexilate methanesulfonate) is an orally active prodrug of Dabigatran which is a reversible and selective, direct thrombin inhibitor (DTI). Dabigatran selectively and reversibly inhibits human thrombin with Ki of 4.5 nM and thrombin-induced platelet aggregation with IC50 of 10 nM. |
||
| S5074 |
Argatroban MonohydrateArgatroban (Argatroban hydrate, Argipidine) is a direct, selective thrombin inhibitor with anticoagulant effects. |
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| S2196 |
Dabigatran (BIBR 953)Dabigatran (BIBR 953) is a potent nonpeptide thrombin inhibitor with an IC50 of 9.3 nM in a cell-free assay. |
|
|
| S2154 |
Dabigatran (BIBR-1048) etexilateDabigatran Etexilate (BIBR-1048) is the prodrug of dabigatran, a potent, nonpeptidic small molecule that specifically and reversibly inhibits both free and clot-bound thrombin by binding to the active site of the thrombin molecule. |
|
|
| S1346 |
Heparin sodiumHeparin sodium, a sulfated polysaccharide belonging to the family of glycosaminoglycans, has numerous important biological activities associated with its interaction with diverse proteins. Heparin is used as an anticoagulant primarily through its interaction with AT III by enhancing AT-IIImediated inhibition of blood coagulation factors, including thrombin and factor Xa. Heparin prevents the induction of autophagy. |
||
| S2069 |
Argatroban (MCI-9038)Argatroban (MCI-9038) is a potent and selective synthetic thrombin inhibitor with Ki ranging from 5 nM to 39 nM, used as an anticoagulant. |
||
| S4545 |
WarfarinWarfarin (Athrombine K, Coumadin, Coumafene, WARF 42, Zoocoumarin) is one of the most widely used anticoagulant drugs worldwide, used in the prevention of thrombosis and thromboembolism, the formation of blood clots in the blood vessels and their migration elsewhere in the body. |
||
| S5960 |
Dabigatran etexilate mesylateDabigatran etexilate mesylate (Pradaxa, BIBR 1048MS, Dabigatran etexilate methanesulfonate) is an orally active prodrug of Dabigatran which is a reversible and selective, direct thrombin inhibitor (DTI). Dabigatran selectively and reversibly inhibits human thrombin with Ki of 4.5 nM and thrombin-induced platelet aggregation with IC50 of 10 nM. |
||
| S5074 |
Argatroban MonohydrateArgatroban (Argatroban hydrate, Argipidine) is a direct, selective thrombin inhibitor with anticoagulant effects. |
