トロンビン

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S2196 Dabigatran (BIBR 953) <1 mg/mL 0.5 mg/mL 0.01 mg/mL
S2154 Dabigatran Etexilate <1 mg/mL 126 mg/mL 12 mg/mL
S2069 Argatroban <1 mg/mL 9 mg/mL 6 mg/mL
S5074 Argatroban hydrate|Argipidine <1 mg/mL 100 mg/mL 40 mg/mL
S1346 Heparin sodium 100 mg/mL <1 mg/mL <1 mg/mL

Thrombin製品

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S2196

Dabigatran (BIBR 953)

Dabigatran (BIBR 953) is a potent nonpeptide thrombin inhibitor with an IC50 of 9.3 nM in a cell-free assay.

S2154

Dabigatran Etexilate

Dabigatran Etexilate is the prodrug of dabigatran, a potent, nonpeptidic small molecule that specifically and reversibly inhibits both free and clot-bound thrombin by binding to the active site of the thrombin molecule.

S2069

Argatroban

Argatroban is a potent and selective synthetic thrombin inhibitor with Ki ranging from 5 nM to 39 nM, used as an anticoagulant.

S4545

Warfarin

Warfarin is one of the most widely used anticoagulant drugs worldwide, used in the prevention of thrombosis and thromboembolism, the formation of blood clots in the blood vessels and their migration elsewhere in the body.

S5074

Argatroban hydrate|Argipidine

Argatroban is a direct, selective thrombin inhibitor with anticoagulant effects.

S1346

Heparin sodium

Heparin sodium, a sulfated polysaccharide belonging to the family of glycosaminoglycans, has numerous important biological activities associated with its interaction with diverse proteins, used as an anticoagulant.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S2196

Dabigatran (BIBR 953)

Dabigatran (BIBR 953) is a potent nonpeptide thrombin inhibitor with an IC50 of 9.3 nM in a cell-free assay.

S2154

Dabigatran Etexilate

Dabigatran Etexilate is the prodrug of dabigatran, a potent, nonpeptidic small molecule that specifically and reversibly inhibits both free and clot-bound thrombin by binding to the active site of the thrombin molecule.

S2069

Argatroban

Argatroban is a potent and selective synthetic thrombin inhibitor with Ki ranging from 5 nM to 39 nM, used as an anticoagulant.

S4545

Warfarin

Warfarin is one of the most widely used anticoagulant drugs worldwide, used in the prevention of thrombosis and thromboembolism, the formation of blood clots in the blood vessels and their migration elsewhere in the body.

S5074

Argatroban hydrate|Argipidine

Argatroban is a direct, selective thrombin inhibitor with anticoagulant effects.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S1346

Heparin sodium

Heparin sodium, a sulfated polysaccharide belonging to the family of glycosaminoglycans, has numerous important biological activities associated with its interaction with diverse proteins, used as an anticoagulant.

2019, 10.1007/s13238-019-0610-7

2019, 54(3):1061-1070