AhR

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S8842 BAY-218 <1 mg/mL 80 mg/mL 20 mg/mL
S2858 StemRegenin 1 (SR1) <1 mg/mL 86 mg/mL <1 mg/mL
S7711 CH-223191 <1 mg/mL 66 mg/mL 4 mg/mL
S6560 PDM2 <1 mg/mL 57 mg/mL 14 mg/mL
s9092 Norisoboldine -1 mg/mL 62 mg/mL -1 mg/mL
S7510 UM729 <1 mg/mL 48 mg/mL 9 mg/mL

AhR製品

新AhR製品
製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S8842

BAY-218

BAY-218 is a potent and selective small-molecule AhR inhibitor, inhibiting AhR nuclear translocation, dioxin response element (DRE)-luciferase reporter expression and AhR-regulated target gene expression induced by both exogenous and endogenous AhR ligands.

S2858

StemRegenin 1 (SR1)

StemRegenin 1 is an aryl hydrocarbon receptor (AhR) inhibitor with IC50 of 127 nM in a cell-free assay.

S7711

CH-223191

CH-223191 is a potent and specific aryl hydrocarbon receptor (AhR) antagonist with IC50 of 30 nM.

S6560

PDM2

PDM2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.

s9092

Norisoboldine

Norisoboldine, a natural aryl hydrocarbon receptor (AhR) agonist, attenuates ulcerative colitis (UC) and induces the generation of Treg cells.

S7510

UM729

UM729 is an enhancer of aryl hydrocarbon receptor (AhR) antagonists.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S8842

BAY-218

BAY-218 is a potent and selective small-molecule AhR inhibitor, inhibiting AhR nuclear translocation, dioxin response element (DRE)-luciferase reporter expression and AhR-regulated target gene expression induced by both exogenous and endogenous AhR ligands.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S2858

StemRegenin 1 (SR1)

StemRegenin 1 is an aryl hydrocarbon receptor (AhR) inhibitor with IC50 of 127 nM in a cell-free assay.

2019, 10.3324/haematol.2018.205534

2019, 10.1111/jcpe.13166

2018, 9(1):4775

S7711

CH-223191

CH-223191 is a potent and specific aryl hydrocarbon receptor (AhR) antagonist with IC50 of 30 nM.

2018, 9(1):4775

2018, 14(12):2172-2184

2018, 53(4):1657-1666

S6560

PDM2

PDM2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
s9092

Norisoboldine

Norisoboldine, a natural aryl hydrocarbon receptor (AhR) agonist, attenuates ulcerative colitis (UC) and induces the generation of Treg cells.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S7510

UM729

UM729 is an enhancer of aryl hydrocarbon receptor (AhR) antagonists.

2019, 10.3324/haematol.2018.212886