AhR
阻害剤の選択性比較
| カタログ番号 | 製品カタログ | 溶解度(25°C) | ||
|---|---|---|---|---|
| 水 | DMSO | アルコール | ||
| S8842 | BAY-218 | <1 mg/mL | 80 mg/mL | 20 mg/mL |
| S2858 | StemRegenin 1 (SR1) | <1 mg/mL | 86 mg/mL | <1 mg/mL |
| S7711 | CH-223191 | <1 mg/mL | 66 mg/mL | 4 mg/mL |
| S6560 | PDM2 | <1 mg/mL | 57 mg/mL | 14 mg/mL |
| s9092 | Norisoboldine | -1 mg/mL | 62 mg/mL | -1 mg/mL |
| S7510 | UM729 | <1 mg/mL | 48 mg/mL | 9 mg/mL |
AhR製品
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| S8842新 |
BAY-218BAY-218 is a potent and selective small-molecule AhR inhibitor, inhibiting AhR nuclear translocation, dioxin response element (DRE)-luciferase reporter expression and AhR-regulated target gene expression induced by both exogenous and endogenous AhR ligands. |
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| S2858 |
StemRegenin 1 (SR1)StemRegenin 1 is an aryl hydrocarbon receptor (AhR) inhibitor with IC50 of 127 nM in a cell-free assay. |
(A,B): Number of total cells and percentage CD41a+ and CD42b+ cells from day 6 + 7 cultures induced by the various cytokine cocktails. Data are mean ± SD; n = 5. *, p<.05; **, p<.01; ***, p<.001
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| S7711 |
CH-223191CH-223191 is a potent and specific aryl hydrocarbon receptor (AhR) antagonist with IC50 of 30 nM. |
Western blots for LLC cells treated for 24 h with PM2 5 or 10 μM chrysene (diluted in DMSO to make a stock solution of 10 mM) with or without 1 μM AhR inhibitor (CH-223191, diluted in DMSO to make a stock solution of 1 mM).
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| S6560新 |
PDM2PDM2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist. |
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| s9092 |
NorisoboldineNorisoboldine, a natural aryl hydrocarbon receptor (AhR) agonist, attenuates ulcerative colitis (UC) and induces the generation of Treg cells. |
||
| S7510 |
UM729UM729 is an enhancer of aryl hydrocarbon receptor (AhR) antagonists. |
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| S8842新 |
BAY-218BAY-218 is a potent and selective small-molecule AhR inhibitor, inhibiting AhR nuclear translocation, dioxin response element (DRE)-luciferase reporter expression and AhR-regulated target gene expression induced by both exogenous and endogenous AhR ligands. |
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| S2858 |
StemRegenin 1 (SR1)StemRegenin 1 is an aryl hydrocarbon receptor (AhR) inhibitor with IC50 of 127 nM in a cell-free assay. |
2019, 10.3324/haematol.2018.205534 2019, 10.1111/jcpe.13166 2018, 9(1):4775 |
(A,B): Number of total cells and percentage CD41a+ and CD42b+ cells from day 6 + 7 cultures induced by the various cytokine cocktails. Data are mean ± SD; n = 5. *, p<.05; **, p<.01; ***, p<.001
|
| S7711 |
CH-223191CH-223191 is a potent and specific aryl hydrocarbon receptor (AhR) antagonist with IC50 of 30 nM. |
2018, 9(1):4775 2018, 14(12):2172-2184 2018, 53(4):1657-1666 |
Western blots for LLC cells treated for 24 h with PM2 5 or 10 μM chrysene (diluted in DMSO to make a stock solution of 10 mM) with or without 1 μM AhR inhibitor (CH-223191, diluted in DMSO to make a stock solution of 1 mM).
|
| S6560新 |
PDM2PDM2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist. |
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| s9092 |
NorisoboldineNorisoboldine, a natural aryl hydrocarbon receptor (AhR) agonist, attenuates ulcerative colitis (UC) and induces the generation of Treg cells. |
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| S7510 |
UM729UM729 is an enhancer of aryl hydrocarbon receptor (AhR) antagonists. |
2019, 10.3324/haematol.2018.212886 2019, 3(19):2825-2835 |
