| S2057 |
Cyclophosphamide Monohydrate
|
Cyclophosphamide Monohydrate is a nitrogen mustard alkylating agent, it attaches the alkyl group to the guanine base of DNA, shown to crosslink DNA, causing strand breakage and inducing mutations.Cyclophosphamide (NSC-26271) Monohydrate can be used to induce animal models of Anemia. |
-
Cell Rep Med, 2025, S2666-3791(25)00102-8
-
Cell Mol Life Sci, 2025, 82(1):164
-
Int J Mol Sci, 2025, 26(17)8494
|
|
| S8126 |
MK571
|
MK571 is a selective, orally active CysLT1 receptor(Cysteinyl leukotriene receptor) antagonist. |
-
Nat Commun, 2025, 16(1):6942
-
STAR Protoc, 2025, 6(2):103777
-
Cancers (Basel), 2023, 15(15)3774
|
|
| S4154 |
Cholesterol
|
Cholesterol(Cholesterin) is the principal sterol of all higher animals required to build and maintain membranes. |
-
Nat Commun, 2024, 15(1):6740
-
Mar Drugs, 2024, 22(4)174
-
Clin Transl Med, 2023, 13(9):e1415
|
|
| S1601 |
Reserpine
|
Reserpine is an inhibitor of multidrug efflux pumps, used as an antipsychotic and antihypertensive drug.Reserpine can be used to induce animal models of Gastric and Intestinal Ulcers. |
-
Mol Psychiatry, 2025, 10.1038/s41380-025-03374-6
-
J Immunother Cancer, 2024, 12(11)e009805
-
Int J Mol Sci, 2022, 23(9)4597
|
|
| S1622 |
Prednisone
|
Prednisone is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound. |
-
Chin Med, 2025, 20(1):135
-
Blood Cancer J, 2022, 12(3):36
-
Int J Mol Sci, 2022, 23(7)3834
|
|
| S1217 |
Cyclophosphamide
|
Cyclophosphamide(NSC 26271,Endoxan, Cytoxan, Neosar, Procytox, Revimmune, Cytophosphane) is a nitrogen mustard alkylating agent from the oxazophorines group. |
-
Neurotherapeutics, 2025, 22(1):e00480
-
Sci Rep, 2025, 15(1):2893
-
Front Biosci (Landmark Ed), 2025, 30(11):45744
|
|
| S2555 |
Clarithromycin
|
Clarithromycin (A-56268) is a macrolide antibiotic and a CYP3A4 inhibitor, used to treat a number of bacterial infections. |
-
Circulation, 2024, 150(7):563-576
-
Microorganisms, 2022, 10(7)1421
-
Cell Biol Toxicol, 2021, 10.1007/s10565-021-09646-5
|
|
| S1645 |
Ketoprofen
|
Ketoprofen (RP-19583) is a dual COX1/2 inhibitor, used as a nonsteroidal anti-inflammatory drug to treat arthritis-related inflammatory pains. |
-
Signal Transduct Target Ther, 2022, 7(1):46
-
J Nucl Med, 2020, jnumed.120.249367
|
|
| S1424 |
Prazosin HCl
|
Prazosin HCl (cp-12299-1) is a competitive alpha-1 adrenoceptor antagonist, used to treat high blood pressure or benign prostatic hyperplasia. |
-
J Physiol Sci, 2025, 75(2):100016
-
J Immunother Cancer, 2024, 12(11)e009805
-
BMC Pharmacol Toxicol, 2020, 21(1):61
|
|
| S2466 |
Estriol
|
Estriol (NSC-12169) is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells. |
-
Mol Cell, 2019, 75(6):1103-1116.e9
|
|
| S1679 |
Flurbiprofen
|
Flurbiprofen is a member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs). |
|
|
| S2076 |
Lisinopril dihydrate
|
Lisinopril dihydrate(MK-521 dihydrate) is an angiotensin-converting enzyme (ACE) inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications of diabetes. |
-
J Immunother Cancer, 2024, 12(11)e009805
|
|
| E2970 |
Gramicidin
|
Gramicidin from Bacillus aneurinolyticus (Bacillus brevis) is an antimicrobial peptide that destroys gram-positive bacteria. It inhibits the growth of bacteria by forming pores and channels in the cell wall, which increase its permeability to monovalent cations. |
|
|
| S5789 |
Propafenone
|
Propafenone (SA-79) is an orally active sodium channel blocking agent and a beta-adrenoceptor (β-adrenergic receptor) antagonist. Propafenone offers a broad spectrum of activity in the treatment of cardiac arrhythmias.Propafenone can be used to induce animal models of Heart Failure. |
|
|
| E4812 |
Fluoxetine
|
Fluoxetine (LY-110140 free base) is a selective 5-hydroxytryptamine (5-HT) reuptake inhibitor. Fluoxetine is used widely in the treatment of depression, anxiety-related symptoms and also displays anticonvulsant activity. |
|
|
| S4210 |
Benzocaine
|
Benzocaine(ethyl 4-aminobenzoate) is the ethyl ester of p-aminobenzoic acid (PABA), it is a local anesthetic commonly used as a topical pain reliever or in cough drops. |
|
|
| E6074New |
Reserpine hydrochloride
|
Reserpine hydrochloride (Serpivite hydrochloride) is a potent inhibitor of the vesicular monoamine transporter 2 (VMAT2) and depletes monoamines from nerve terminals. It exhibits the potential to produce a pharmacological model of depression in animals. |
|
|
| E0209 |
Cinobufotalin
|
Cinobufotalin, extracted from the skin secretion of the giant toad, is a novel SREBP1 inhibitor that suppresses proliferation of hepatocellular carcinoma by targeting lipogenesis. |
|
|
| E4900 |
Enalapril
|
Enalapril(Eletriptan, Amprace, Vaseretic) is an inhibitor of angiotensin-converting enzyme (ACE), primarily used to treat hypertension, heart failure, and asymptomatic left ventricular dysfunction. It also attenuates frailty in aging mice. |
-
Biochem Pharmacol, 2025, 240:117098
|
|
| S4154 |
Cholesterol
|
Cholesterol(Cholesterin) is the principal sterol of all higher animals required to build and maintain membranes. |
-
Nat Commun, 2024, 15(1):6740
-
Mar Drugs, 2024, 22(4)174
-
Clin Transl Med, 2023, 13(9):e1415
|
|
| S1622 |
Prednisone
|
Prednisone is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound. |
-
Chin Med, 2025, 20(1):135
-
Blood Cancer J, 2022, 12(3):36
-
Int J Mol Sci, 2022, 23(7)3834
|
|
| S8126 |
MK571
|
MK571 is a selective, orally active CysLT1 receptor(Cysteinyl leukotriene receptor) antagonist. |
- Nat Commun, 2025, 16(1):6942
- STAR Protoc, 2025, 6(2):103777
- Cancers (Basel), 2023, 15(15)3774
|
|
| S1601 |
Reserpine
|
Reserpine is an inhibitor of multidrug efflux pumps, used as an antipsychotic and antihypertensive drug.Reserpine can be used to induce animal models of Gastric and Intestinal Ulcers. |
- Mol Psychiatry, 2025, 10.1038/s41380-025-03374-6
- J Immunother Cancer, 2024, 12(11)e009805
- Int J Mol Sci, 2022, 23(9)4597
|
|
| S1217 |
Cyclophosphamide
|
Cyclophosphamide(NSC 26271,Endoxan, Cytoxan, Neosar, Procytox, Revimmune, Cytophosphane) is a nitrogen mustard alkylating agent from the oxazophorines group. |
- Neurotherapeutics, 2025, 22(1):e00480
- Sci Rep, 2025, 15(1):2893
- Front Biosci (Landmark Ed), 2025, 30(11):45744
|
|
| S2555 |
Clarithromycin
|
Clarithromycin (A-56268) is a macrolide antibiotic and a CYP3A4 inhibitor, used to treat a number of bacterial infections. |
- Circulation, 2024, 150(7):563-576
- Microorganisms, 2022, 10(7)1421
- Cell Biol Toxicol, 2021, 10.1007/s10565-021-09646-5
|
|
| S1645 |
Ketoprofen
|
Ketoprofen (RP-19583) is a dual COX1/2 inhibitor, used as a nonsteroidal anti-inflammatory drug to treat arthritis-related inflammatory pains. |
- Signal Transduct Target Ther, 2022, 7(1):46
- J Nucl Med, 2020, jnumed.120.249367
|
|
| S2076 |
Lisinopril dihydrate
|
Lisinopril dihydrate(MK-521 dihydrate) is an angiotensin-converting enzyme (ACE) inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications of diabetes. |
- J Immunother Cancer, 2024, 12(11)e009805
|
|
| E2970 |
Gramicidin
|
Gramicidin from Bacillus aneurinolyticus (Bacillus brevis) is an antimicrobial peptide that destroys gram-positive bacteria. It inhibits the growth of bacteria by forming pores and channels in the cell wall, which increase its permeability to monovalent cations. |
|
|
| S5789 |
Propafenone
|
Propafenone (SA-79) is an orally active sodium channel blocking agent and a beta-adrenoceptor (β-adrenergic receptor) antagonist. Propafenone offers a broad spectrum of activity in the treatment of cardiac arrhythmias.Propafenone can be used to induce animal models of Heart Failure. |
|
|
| E4812 |
Fluoxetine
|
Fluoxetine (LY-110140 free base) is a selective 5-hydroxytryptamine (5-HT) reuptake inhibitor. Fluoxetine is used widely in the treatment of depression, anxiety-related symptoms and also displays anticonvulsant activity. |
|
|
| S4210 |
Benzocaine
|
Benzocaine(ethyl 4-aminobenzoate) is the ethyl ester of p-aminobenzoic acid (PABA), it is a local anesthetic commonly used as a topical pain reliever or in cough drops. |
|
|
| E6074New |
Reserpine hydrochloride
|
Reserpine hydrochloride (Serpivite hydrochloride) is a potent inhibitor of the vesicular monoamine transporter 2 (VMAT2) and depletes monoamines from nerve terminals. It exhibits the potential to produce a pharmacological model of depression in animals. |
|
|
| E0209 |
Cinobufotalin
|
Cinobufotalin, extracted from the skin secretion of the giant toad, is a novel SREBP1 inhibitor that suppresses proliferation of hepatocellular carcinoma by targeting lipogenesis. |
|
|
| E4900 |
Enalapril
|
Enalapril(Eletriptan, Amprace, Vaseretic) is an inhibitor of angiotensin-converting enzyme (ACE), primarily used to treat hypertension, heart failure, and asymptomatic left ventricular dysfunction. It also attenuates frailty in aging mice. |
- Biochem Pharmacol, 2025, 240:117098
|
|