Progesterone Receptor

Progesterone Receptor製品

All (27)
Progesterone Receptor阻害剤 (2)
Progesterone Receptor拮抗剤(1)
Progesterone Receptor作動薬(9)
Progesterone Receptorモジュレータ(1)
新製品

製品コード	製品名称	製品説明	文献中Selleckの製品使用例
S2606	Mifepristone (RU486)	Mifepristone is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively. Mifepristone promotes cell autophagy and apoptosis, decreases Bcl-2 level and increases Beclin1 level, accompanied by weakened interaction between Bcl-2 and Beclin1.Mifepristone (RU486) can be used to induce animal models of Spontaneous Abortion.	Pharmacol Res, 2025, 215:107696 Cell Death Dis, 2025, 16(1):237 J Virol, 2025, 99(2):e0147224
S2567	MPA (Medroxyprogesterone acetate)	MPA (Medroxyprogesterone acetate) is a synthetic progestin and act as a potent progesterone receptor agonist, used to treat abnormal menstruation or irregular vaginal bleeding.	Cancer Sci, 2025, 10.1111/cas.70081 Cell Prolif, 2024, e13780. J Transl Med, 2024, 22(1):478
S1304	Megestrol Acetate	Megestrol acetate (BDH1298, SC10363) is a synthetic progestogen, used to treat breast cancer and loss of appetite.	iScience, 2024, 27(10):110862 J Pers Med, 2022, 12(2)258 Hum Cell, 2022, 10.1007/s13577-022-00671-y
S1705	Progesterone	Progesterone is an endogenous steroid hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. A potent agonist of the nuclear progesterone receptor (nPR) with Kd of 1 nM; An agonist of the membrane progesterone receptors(mPRs); An antagonist of the σ1 receptor.	Bone Res, 2025, 13(1):37 Nat Commun, 2024, 15(1):8708 Dev Cell, 2024, S1534-5807(24)00326-5
S1377	Drospirenone	Drospirenone (ZK 3059) is a synthetic progestin that is an analog to spironolactone.	Acta Pharm Sin B, 2023, 13(2):662-677 Nat Cancer, 2020, 1(2):235-248 J Thromb Haemost, 2015, 13(10):1918-24
S3081	Ulipristal Acetate (CDB 2914)	Ulipristal acetate (CDB-2914, HRP 2000, RU 44675) is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure.	Nature, 2025, 10.1038/s41586-025-09684-7 J Clin Endocrinol Metab, 2019, 104(12):6256-6264 Cell Prolif, 2017, 50(5)
S4040	Norethindrone	Norethindrone (Norethisterone) is a synthetic progestin, which mimic the actions of the endogenous ovarian hormone progesterone.	Nat Cancer, 2020, 1(2):235-248
S1251	Dienogest	Dienogest (STS 557) is an orally active synthetic progesterone, used for contraception and the treatment of endometriosis.
S3167	Altrenogest	Altrenogest (A35957, RU2267,R2267) is a progestogen structurally related to veterinary steroid trenbolone.
E0527	Norgestimate	Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity.
E0937	Segesterone acetate	Segesterone acetate (Nestoron, ST-1435) is a synthetic progestin that binds to the progesterone receptor with EC50 of 50.3 nM.
S4638	Desogestrel	Desogestrel (Cerazette, Desogen, Desogestrelum, Org-2969) is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.
S4883	Lynestrenol	Lynestrenol (Ethinylestrenol) is a synthetic progestational hormone, an agonist of the progesterone receptor and has weak androgenic and estrogenic activity.
S3635	Medroxyprogesterone	Medroxyprogesterone (MP) is a synthetic pregnane steroid and a derivative of progesterone. It is a potent progesterone receptor agonist.
S4097	Dydrogesterone	Dydrogesterone (NSC 92336) is an orally active progestogen which acts directly on the uterus, producing a complete secretory endometrium in an estrogen-primed uterus.
S4507	17-Hydroxyprogesterone	17-Hydroxyprogesterone (17-OHP) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.
E2664	Cridanimod	Cridanimod, a low-Mw interferon-inducer (IFN-inducer), recognizes the intracellular signaling protein stimulator of interferon genes (STING), resulting in the STING-TBK1-IRF3 pathway activation and synthesis of type I IFNs (subtypes IFN-α and IFN-β).
E0742	Melengestrol Acetate	Melengestrol Acetate, progestational steroid suppress the AT3 tumour.
S2567	MPA (Medroxyprogesterone acetate)	MPA (Medroxyprogesterone acetate) is a synthetic progestin and act as a potent progesterone receptor agonist, used to treat abnormal menstruation or irregular vaginal bleeding.	Cancer Sci, 2025, 10.1111/cas.70081 Cell Prolif, 2024, e13780. J Transl Med, 2024, 22(1):478
S1705	Progesterone	Progesterone is an endogenous steroid hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. A potent agonist of the nuclear progesterone receptor (nPR) with Kd of 1 nM; An agonist of the membrane progesterone receptors(mPRs); An antagonist of the σ1 receptor.	Bone Res, 2025, 13(1):37 Nat Commun, 2024, 15(1):8708 Dev Cell, 2024, S1534-5807(24)00326-5
S3167	Altrenogest	Altrenogest (A35957, RU2267,R2267) is a progestogen structurally related to veterinary steroid trenbolone.
S4638	Desogestrel	Desogestrel (Cerazette, Desogen, Desogestrelum, Org-2969) is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.
S4883	Lynestrenol	Lynestrenol (Ethinylestrenol) is a synthetic progestational hormone, an agonist of the progesterone receptor and has weak androgenic and estrogenic activity.
S3635	Medroxyprogesterone	Medroxyprogesterone (MP) is a synthetic pregnane steroid and a derivative of progesterone. It is a potent progesterone receptor agonist.
S4097	Dydrogesterone	Dydrogesterone (NSC 92336) is an orally active progestogen which acts directly on the uterus, producing a complete secretory endometrium in an estrogen-primed uterus.
S4507	17-Hydroxyprogesterone	17-Hydroxyprogesterone (17-OHP) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.
E2664	Cridanimod	Cridanimod, a low-Mw interferon-inducer (IFN-inducer), recognizes the intracellular signaling protein stimulator of interferon genes (STING), resulting in the STING-TBK1-IRF3 pathway activation and synthesis of type I IFNs (subtypes IFN-α and IFN-β).
S1304	Megestrol Acetate	Megestrol acetate (BDH1298, SC10363) is a synthetic progestogen, used to treat breast cancer and loss of appetite.	iScience, 2024, 27(10):110862 J Pers Med, 2022, 12(2)258 Hum Cell, 2022, 10.1007/s13577-022-00671-y
E0742	Melengestrol Acetate	Melengestrol Acetate, progestational steroid suppress the AT3 tumour.
S2606	Mifepristone (RU486)	Mifepristone is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively. Mifepristone promotes cell autophagy and apoptosis, decreases Bcl-2 level and increases Beclin1 level, accompanied by weakened interaction between Bcl-2 and Beclin1.Mifepristone (RU486) can be used to induce animal models of Spontaneous Abortion.	Pharmacol Res, 2025, 215:107696 Cell Death Dis, 2025, 16(1):237 J Virol, 2025, 99(2):e0147224
S2567	MPA (Medroxyprogesterone acetate)	MPA (Medroxyprogesterone acetate) is a synthetic progestin and act as a potent progesterone receptor agonist, used to treat abnormal menstruation or irregular vaginal bleeding.	Cancer Sci, 2025, 10.1111/cas.70081 Cell Prolif, 2024, e13780. J Transl Med, 2024, 22(1):478
S1705	Progesterone	Progesterone is an endogenous steroid hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. A potent agonist of the nuclear progesterone receptor (nPR) with Kd of 1 nM; An agonist of the membrane progesterone receptors(mPRs); An antagonist of the σ1 receptor.	Bone Res, 2025, 13(1):37 Nat Commun, 2024, 15(1):8708 Dev Cell, 2024, S1534-5807(24)00326-5
S3167	Altrenogest	Altrenogest (A35957, RU2267,R2267) is a progestogen structurally related to veterinary steroid trenbolone.
S4638	Desogestrel	Desogestrel (Cerazette, Desogen, Desogestrelum, Org-2969) is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.
S4883	Lynestrenol	Lynestrenol (Ethinylestrenol) is a synthetic progestational hormone, an agonist of the progesterone receptor and has weak androgenic and estrogenic activity.
S3635	Medroxyprogesterone	Medroxyprogesterone (MP) is a synthetic pregnane steroid and a derivative of progesterone. It is a potent progesterone receptor agonist.
S4097	Dydrogesterone	Dydrogesterone (NSC 92336) is an orally active progestogen which acts directly on the uterus, producing a complete secretory endometrium in an estrogen-primed uterus.
S4507	17-Hydroxyprogesterone	17-Hydroxyprogesterone (17-OHP) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.
E2664	Cridanimod	Cridanimod, a low-Mw interferon-inducer (IFN-inducer), recognizes the intracellular signaling protein stimulator of interferon genes (STING), resulting in the STING-TBK1-IRF3 pathway activation and synthesis of type I IFNs (subtypes IFN-α and IFN-β).
S3081	Ulipristal Acetate (CDB 2914)	Ulipristal acetate (CDB-2914, HRP 2000, RU 44675) is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure.	Nature, 2025, 10.1038/s41586-025-09684-7 J Clin Endocrinol Metab, 2019, 104(12):6256-6264 Cell Prolif, 2017, 50(5)