Reductase

Reductase製品

All (11)
Reductase阻害剤 (9)
新製品

製品コード	製品名称	製品説明	文献中Selleckの製品使用例
S2404	Isoliquiritigenin	Isoliquiritigenin, an anti-tumor flavonoid from the root of Glycyrrhiza glabra, inhibits aldose reductase with an IC50 of 320 nM.	J Nutr Biochem, 2024, 136:109808 Biomedicines, 2022, 10(3)638 Cancer Res, 2021, 81(16):4257-4274
S1202	Dutasteride	Dutasteride (GI198745, GG-745) is a dual 5-α reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT).	Neoplasia, 2024, 57:101045 Food Chem Toxicol, 2023, 176:113764 Cancer Rep (Hoboken), 2021, e1418
S1197	Finasteride	Finasteride (MK-906) is a potent, reversible inhibitor of the rat type 1 5 alpha-reductase with K_i of 10.2 nM, used in the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB).	Biochem Pharmacol, 2025, 241:117171 Drug Des Devel Ther, 2025, 19:2393-2409 J Ethnopharmacol, 2024, 330:118227
S2035	Epalrestat	Epalrestat is an aldose reductase inhibitor with IC50 of 72 nM.	Cell Rep Med, 2023, 4(6):101056 Cell Rep Med, 2023, 4(6):101056 Free Radic Biol Med, 2021, 163:220-233
S9170	Engeletin	Engeletin (Dihydrokaempferol 3-rhamnoside), a bioactive flavonoid, has multiple biological activities such as anti-diabetic and anti-inflammatory effects. engeletin againsts LPS-stimulated endometritis in mice via negative regulation of pro-inflammatory mediators via the TLR4-regulated NF-κB pathway.	J Inflamm Res, 2022, 15:5767-5783 Biochem Biophys Res Commun, 2020, 526(2):497-504
S5803	Alrestatin	Alrestatin is an inhibitor of aldose reductase which is involved in the pathogenesis of complications of diabetes mellitus, including diabetic neuropathy.	iScience, 2022, 25(4):104153
S5910	Alpha-Estradiol	Alpha-Estradiol (α-Estradiol, 17 alpha-Estradiol, Alfatradiol, Epiestradiol, Epiestrol, Alora, 17 α-E2), a natural, non-feminizing stereoisomer, a hormonally almost inactive isomer of physiological 17 beta-estradiol (17 β-E2), is a weak inhibitor of estrogen.	Biomater Res, 2024, 28:0010
S3818	Tectoridin	Tectoridin (Shekanin), an isoflavone isolated from flowers of Pueraria thunbergiana, has several pharmacological effects including anti-cancer, anti-inflammatory, antioxidant, and hepatoprotectivy.
S1074	Poliumoside	Poliumoside exhibits significant inhibition of advanced glycation end product formation with IC50 values of 19.69 µM. In the rat lens aldose reductase assay. Poliumoside exhibits greater inhibitory effects on rat lens aldose reductase(RLAR) with IC50 values of 8.47 µM.
S5446	2-Chloro-1-(4-fluorobenzyl)benzimidazole	2-Chloro-1-(4-fluorobenzyl)benzimidazole is an aldose reductase (ALR2) inhibitor which is used for preparation of disubstituted benzimidazole derivative.
S9103	Ginsenoside Ro	Ginsenoside Ro (Chikusetsusaponin V), one of the high-abundance saponins in ginseng, is widely used as a dietary supplement and has many health-promoting effects.
S2404	Isoliquiritigenin	Isoliquiritigenin, an anti-tumor flavonoid from the root of Glycyrrhiza glabra, inhibits aldose reductase with an IC50 of 320 nM.	J Nutr Biochem, 2024, 136:109808 Biomedicines, 2022, 10(3)638 Cancer Res, 2021, 81(16):4257-4274
S1202	Dutasteride	Dutasteride (GI198745, GG-745) is a dual 5-α reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT).	Neoplasia, 2024, 57:101045 Food Chem Toxicol, 2023, 176:113764 Cancer Rep (Hoboken), 2021, e1418
S1197	Finasteride	Finasteride (MK-906) is a potent, reversible inhibitor of the rat type 1 5 alpha-reductase with K_i of 10.2 nM, used in the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB).	Biochem Pharmacol, 2025, 241:117171 Drug Des Devel Ther, 2025, 19:2393-2409 J Ethnopharmacol, 2024, 330:118227
S2035	Epalrestat	Epalrestat is an aldose reductase inhibitor with IC50 of 72 nM.	Cell Rep Med, 2023, 4(6):101056 Cell Rep Med, 2023, 4(6):101056 Free Radic Biol Med, 2021, 163:220-233
S9170	Engeletin	Engeletin (Dihydrokaempferol 3-rhamnoside), a bioactive flavonoid, has multiple biological activities such as anti-diabetic and anti-inflammatory effects. engeletin againsts LPS-stimulated endometritis in mice via negative regulation of pro-inflammatory mediators via the TLR4-regulated NF-κB pathway.	J Inflamm Res, 2022, 15:5767-5783 Biochem Biophys Res Commun, 2020, 526(2):497-504
S5803	Alrestatin	Alrestatin is an inhibitor of aldose reductase which is involved in the pathogenesis of complications of diabetes mellitus, including diabetic neuropathy.	iScience, 2022, 25(4):104153
S5910	Alpha-Estradiol	Alpha-Estradiol (α-Estradiol, 17 alpha-Estradiol, Alfatradiol, Epiestradiol, Epiestrol, Alora, 17 α-E2), a natural, non-feminizing stereoisomer, a hormonally almost inactive isomer of physiological 17 beta-estradiol (17 β-E2), is a weak inhibitor of estrogen.	Biomater Res, 2024, 28:0010
S1074	Poliumoside	Poliumoside exhibits significant inhibition of advanced glycation end product formation with IC50 values of 19.69 µM. In the rat lens aldose reductase assay. Poliumoside exhibits greater inhibitory effects on rat lens aldose reductase(RLAR) with IC50 values of 8.47 µM.
S5446	2-Chloro-1-(4-fluorobenzyl)benzimidazole	2-Chloro-1-(4-fluorobenzyl)benzimidazole is an aldose reductase (ALR2) inhibitor which is used for preparation of disubstituted benzimidazole derivative.