PPARγ 選択性阻害剤 | 作動薬 | 拮抗剤

製品コード 製品名 製品説明 Selective / Pan IC50 / Ki
S2871 T0070907

T0070907 is a potent and selective PPARγ inhibitor with IC50 of 1 nM, with a >800-fold selectivity over PPARα and PPARδ.

Selective PPARγ, IC50: 1 nM
S2505 Rosiglitazone maleate

Rosiglitazone, a member of the thiazolidinedione class of antihyperglycaemic agents, is a high-affinity selective agonist of the peroxisome proliferator-activated receptor-γ.

Selective PPARγ, IC50: 42 nM
S2590 Pioglitazone

Pioglitazone is a selective peroxisome proliferator-activated receptor-gamma (PPARgamma) agonist, used to treat diabetes.

S2915 GW9662

GW9662 is a selective PPAR antagonist for PPARγ with IC50 of 3.3 nM, with at least 100 to 1000-fold functional selectivity in cells with PPARγ versus PPARα and PPARδ.

Pan PPARγ, IC50: 3.3 nM
S7484 FH535

FH535 is a Wnt/β-catenin signaling inhibitor and also a dual PPARγ and PPARδ antagonist.