Spartalizumab (anti-PD-1)

製品コードA2017 別名: PDR001 Non-humanized mouse model applicable

For research use only. Not for use in humans.

Spartalizumab is a humanized anti-PD-1 IgG4 antibody that blocks the binding of PD-L1 and PD-L2 to PD-1. It binds to PD-1 with high affinity and inhibits the biological activity of PD-1.

サイズ 価格(税別)  
JPY 117362.00

質量管理及び製品安全説明書

PD-1/PD-L1阻害剤の選択性比較

生物活性

製品説明 Spartalizumab is a humanized anti-PD-1 IgG4 antibody that blocks the binding of PD-L1 and PD-L2 to PD-1. It binds to PD-1 with high affinity and inhibits the biological activity of PD-1.
ターゲット
PD-1 [1]
()
体内試験 In phase 1/2 studies, PDR001 has a manageable safety profile and preliminary antitumor activity in advanced solid tumors[1].

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製品説明

Formulation PBS buffer, pH 7.2
Isotype Human IgG4
Source CHO cells
Storage Store at -80°C and avoid freeze-thaw cycles.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID