Fungal
阻害剤の選択性比較
カタログ番号 | 製品カタログ | 溶解度(25°C) | ||
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水 | DMSO | アルコール | ||
S1517 | Natamycin | <1 mg/mL | 7 mg/mL | '<1 mg/mL |
S2476 | Itraconazole (R 51211) | <1 mg/mL | 7 mg/mL | '''<1 mg/mL |
S1331 | Fluconazole (UK 49858) | <1 mg/mL | 61 mg/mL | ''61 mg/mL |
S1934 | Nystatin (Fungicidin) | <1 mg/mL | 19 mg/mL | <1 mg/mL |
S1725 | Terbinafine | <1 mg/mL | 58 mg/mL | '58 mg/mL |
S1606 | Clotrimazole | <1 mg/mL | 11 mg/mL | '69 mg/mL |
S1956 | Miconazole Nitrate | <1 mg/mL | 96 mg/mL | '1 mg/mL |
S1666 | Flucytosine | 5 mg/mL | 8 mg/mL | '''<1 mg/mL |
S2557 | Terbinafine HCl | <1 mg/mL | 66 mg/mL | '66 mg/mL |
S3073 | Caspofungin (MK-0991) Acetate | 100 mg/mL | -1 mg/mL | '''-1 mg/mL |
S2528 | Ciclopirox | <1 mg/mL | 42 mg/mL | '42 mg/mL |
S3019 | Ciclopirox ethanolamine | <1 mg/mL | 6 mg/mL | '30 mg/mL |
S2535 | Econazole nitrate | <1 mg/mL | 89 mg/mL | ''5 mg/mL |
S1854 | Bifonazole | <1 mg/mL | 62 mg/mL | '20 mg/mL |
S3079 | Atovaquone | <1 mg/mL | 5 mg/mL | '<1 mg/mL |
S1997 | Liranaftate | <1 mg/mL | <1 mg/mL | ''<1 mg/mL |
S3161 | Sertaconazole nitrate | <1 mg/mL | 100 mg/mL | '<1 mg/mL |
S2031 | Fenticonazole Nitrate | <1 mg/mL | 104 mg/mL | '2 mg/mL |
S1676 | Amorolfine HCl | 9 mg/mL | 28 mg/mL | '71 mg/mL |
S4075 | Zinc Pyrithione | <1 mg/mL | 30 mg/mL | '<1 mg/mL |
S2536 | Miconazole | <1 mg/mL | 83 mg/mL | '83 mg/mL |
S1910 | Tioconazole | <1 mg/mL | 78 mg/mL | '78 mg/mL |
S4120 | Sulconazole Nitrate | <1 mg/mL | 92 mg/mL | ''<1 mg/mL |
S3154 | Butenafine HCl | <1 mg/mL | 70 mg/mL | '70 mg/mL |
S3156 | Naftifine HCl | <1 mg/mL | <1 mg/mL | '8 mg/mL |
S1833 | Butoconazole nitrate | <1 mg/mL | 95 mg/mL | ''<1 mg/mL |
S4806 | Potassium 1-Naphthaleneacetate | -1 mg/mL | 44 mg/mL | '-1 mg/mL |
S9200 | Pneumocandin B0 | -1 mg/mL | 100 mg/mL | -1 mg/mL |
S0917 | Allosecurinin | -1 mg/mL | 100 mg/mL | -1 mg/mL |
S6254 | Hydrocinnamic acid | -1 mg/mL | 30 mg/mL | '-1 mg/mL |
S4581 | Triacetin | ' mg/mL | ||
S0938 | Sakuranetin | -1 mg/mL | 57 mg/mL | -1 mg/mL |
S5944 | Butenafine | <1 mg/mL | 63 mg/mL | '63 mg/mL |
S0832 | Dimboa | ' mg/mL | ||
S5359 | Butoconazole | -1 mg/mL | 82 mg/mL | '-1 mg/mL |
S8095 | Tubercidin | <1 mg/mL | 53 mg/mL | '<1 mg/mL |
S3966 | Nifuratel | <1 mg/mL | 57 mg/mL | '<1 mg/mL |
S3373 | Deoxylapachol | ' mg/mL | ||
S3307 | Galangin 3-methyl ether | -1 mg/mL | 100 mg/mL | -1 mg/mL |
S4970 | Nerol | ' mg/mL | ||
S3829 | Isoalantolactone | -1 mg/mL | 46 mg/mL | -1 mg/mL |
S2058 | Tolnaftate | <1 mg/mL | 62 mg/mL | '<1 mg/mL |
S4584 | Butylparaben | 38 mg/mL | 38 mg/mL | '38 mg/mL |
S0770 | Camalexin | ' mg/mL | ||
S0971 | Kakuol | ' mg/mL | ||
S5080 | Neticonazole | 60 mg/mL | 60 mg/mL | ''60 mg/mL |
S4996 | Tavaborole (AN-2690) | <1 mg/mL | 30 mg/mL | ''30 mg/mL |
S5271 | Suloctidil | -1 mg/mL | 67 mg/mL | '-1 mg/mL |
S4755 | lanosterol | <1 mg/mL | <1 mg/mL | '6 mg/mL |
S3532 | AN-2718 | <1 mg/mL | 34 mg/mL | 34 mg/mL |
S3778 | Patchouli alcohol | -1 mg/mL | 44 mg/mL | -1 mg/mL |
S4963 | Purpurin | -1 mg/mL | 51 mg/mL | -1 mg/mL |
S4178 | Climbazole | <1 mg/mL | 59 mg/mL | '59 mg/mL |
S3646 | Thimerosal | 80 mg/mL | 80 mg/mL | ''20 mg/mL |
S6270 | 2-Aminoisobutyric acid | 10 mg/mL | <1 mg/mL | '-1 mg/mL |
S4187 | Salicylanilide | <1 mg/mL | 43 mg/mL | '18 mg/mL |
S3676 | Carbendazim | <1 mg/mL | 17 mg/mL | '<1 mg/mL |
S4258 | Luliconazole | <1 mg/mL | 71 mg/mL | '5 mg/mL |
S9350 | Ethyl 4-Methoxycinnamate | -1 mg/mL | 41 mg/mL | -1 mg/mL |
S9057 | Sinigrin | -1 mg/mL | 79 mg/mL | -1 mg/mL |
S2534 | Isoconazole nitrate | <1 mg/mL | 41 mg/mL | '4 mg/mL |
S5704 | Myclobutanil | -1 mg/mL | 58 mg/mL | '-1 mg/mL |
S3705 | Chlorobutanol | <1 mg/mL | 35 mg/mL | ''35 mg/mL |
S9072 | Sweroside | -1 mg/mL | 71 mg/mL | -1 mg/mL |
S2321 | Magnolol | <1 mg/mL | 53 mg/mL | 53 mg/mL |
S6408 | Hexetidine | ' mg/mL | ||
S5033 | Terconazole | <1 mg/mL | 49 mg/mL | ''100 mg/mL |
S5025 | Efinaconazole | <1 mg/mL | 69 mg/mL | '69 mg/mL |
S3588 | Hexylene glycol | ' mg/mL | ||
S3595 | D-Gluconic acid | ' mg/mL | ||
S9413 | Yangonin | -1 mg/mL | 51 mg/mL | -1 mg/mL |
S5724 | Dichlorophen | -1 mg/mL | 54 mg/mL | ''-1 mg/mL |
S5829 | Monomyristin | <1 mg/mL | 60 mg/mL | '60 mg/mL |
S4601 | Clioquinol | <1 mg/mL | 61 mg/mL | '1 mg/mL |
S6451 | Salifungin | <1 mg/mL | 65 mg/mL | '5 mg/mL |
S3722 | Isavuconazole | <1 mg/mL | 87 mg/mL | '87 mg/mL |
S5541 | Dimetridazole | -1 mg/mL | 28 mg/mL | '-1 mg/mL |
S3979 | Zinc Undecylenate | -1 mg/mL | 36 mg/mL | '-1 mg/mL |
S6467 | Fosfluconazole | <1 mg/mL | 19 mg/mL | '<1 mg/mL |
S9444 | Tomatine | -1 mg/mL | 100 mg/mL | -1 mg/mL |
S4525 | Ethylparaben | <1 mg/mL | 33 mg/mL | ''33 mg/mL |
S4878 | Neticonazole Hydrochloride | -1 mg/mL | 67 mg/mL | '-1 mg/mL |
S5845 | Chalcone | <1 mg/mL | 42 mg/mL | ''42 mg/mL |
S4793 | Cedryl acetate | -1 mg/mL | 52 mg/mL | -1 mg/mL |
S5512 | Juglone | -1 mg/mL | 34 mg/mL | -1 mg/mL |
S4516 | (+)-Camphor | <1 mg/mL | 30 mg/mL | '30 mg/mL |
S5373 | Pseudolaric Acid B | <1 mg/mL | 86 mg/mL | 86 mg/mL |
S4843 | Potassium acetate | -1 mg/mL | 6 mg/mL | '-1 mg/mL |
S4286 | Anidulafungin (LY303366) | <1 mg/mL | 100 mg/mL | '<1 mg/mL |
S3910 | 4',7-Dimethoxyisoflavone | -1 mg/mL | 4 mg/mL | -1 mg/mL |
S4287 | Micafungin (FK 463) Sodium | 100 mg/mL | -1 mg/mL | '''-1 mg/mL |
S4559 | Cloxiquine | <1 mg/mL | 35 mg/mL | ''35 mg/mL |
S3985 | Methyl 4-hydroxybenzoate | -1 mg/mL | 30 mg/mL | '-1 mg/mL |
S0491 | Manogepix (E1210) | <1 mg/mL | 72 mg/mL | '20 mg/mL |
S3990 | Trans-Anethole | -1 mg/mL | 29 mg/mL | -1 mg/mL |
S1442 | Voriconazole (UK-109496) | <1 mg/mL | 70 mg/mL | ''20 mg/mL |
S5174 | Kojic acid | -1 mg/mL | 28 mg/mL | -1 mg/mL |
S5083 | Lentinan | -1 mg/mL | 100 mg/mL | -1 mg/mL |
Fungal製品
製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
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S1517 |
NatamycinNatamycin (Pimaricin), a natural and versatile anti-fungal agent during fermentation by the bacterium Streptomyces natalensis, commonly found in soil; with little to no flavour interference |
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S2476 |
Itraconazole (R 51211)Itraconazole (R 51211) is a relatively potent inhibitor of CYP3A4 with IC50 of 6.1 nM, used as a triazole antifungal agent. Itraconazole is a potent antagonist of the Hedgehog (Hh) signaling pathway. Itraconazole suppresses the growth of glioblastoma through induction of autophagy. |
![]() ![]() Resistance to itraconazole in MA cells. The parental SUM149-Luc cell line and MA1 cells were treated in parallel with 1 mM itraconazole for 9 days (which killed most of the cells in the parental cell line) and were allowed to recover and grow in a drug-free medium for 5 days before being stained. Since itraconazole was ineffective in killing MA1 cells, the cells grew into a continuous monolayer rather than colonies. |
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S1331 |
Fluconazole (UK 49858)Fluconazole (UK 49858) is a fungal lanosterol 14 alpha-demethylase inhibitor, which thereby prevents the formation of ergosterol,used in the treatment and prevention of superficial and systemic fungal infections. |
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S1934 |
Nystatin (Fungicidin)Nystatin, which belongs to the polyene group of antimycotics, is frequently used as a topical agent in the treatment of oro-pharyngeal candidosis. |
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S1725 |
TerbinafineTerbinafine (SF 86-327) is used to treat infections caused by a fungus. It works by killing the fungus or preventing its growth. |
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S1606 |
ClotrimazoleClotrimazole (BAY b 5097, FB 5097) alters the permeability of the fungal cell wall by inhibiting the biosynthesis of ergosterol, used in the treatment of fungal infections. |
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S1956 |
Miconazole NitrateMiconazole (NSC 169434) Nitrate is an imidazole antifungal agent by inhibiting ergosterol biosynthesis and inducing ROS, used to treat vaginal yeast infections. |
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S1666 |
FlucytosineFlucytosine (5-Fluorocytosine, 5-FC, NSC 103805, Ro 2-9915) is an antifungal drug with IC50 of 0.93 μM in C. albicans. |
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S2557 |
Terbinafine HClTerbinafine HCl (KWD 201) inhibits ergosterol synthesis by inhibiting squalene epoxidase, used as an antifungal drug. |
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S3073 |
Caspofungin (MK-0991) AcetateCaspofungin Acetate (MK-0991, L-743872) is an lipopeptide antifungal β-1,3-glucan synthase inhibitor. |
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S2528 |
CiclopiroxCiclopirox is a broad-spectrum antifungal agent working as an iron chelator. |
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S3019 |
Ciclopirox ethanolamineCiclopirox ethanolamine (Ciclopirox olamine, HOE 296) is a broad-spectrum antifungal agent working as an iron chelator. |
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S2535 |
Econazole nitrateEconazole Nitrate (NSC 243115) is a Ca2+ channel blocker, used as an antifungal medicine that fights infections caused by fungus. |
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S1854 |
BifonazoleBifonazole (Bay h 4502) is a substituted imidazole antifungal agent. |
![]() ![]() Percentage of MBP+ oligodendrocytes generated from OPCs following treatment with azoles (c). n ≥ 4 wells per condition.
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S3079 |
AtovaquoneAtovaquone (Atavaquone) is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia. |
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S1997 |
LiranaftateLiranaftate is a squalene epoxidase inhibitor with anti-fungicidal activities. |
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S3161 |
Sertaconazole nitrateSertaconazole nitrate (FI-7045) is a topical broad-spectrum antifungal that is developed to provide an additional agent for the treatment of superficial cutaneous and mucosal infections. |
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S2031 |
Fenticonazole NitrateFenticonazole Nitrate is an azole antifungal agent. |
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S1676 |
Amorolfine HClAmorolfine HCl is an antifungal reagent. |
![]() ![]() b, GC–MS-based quantification of three metabolite levels in human glioma cells (GBM528) treated for 24 h with the indicated small molecules at the following concentrations: tamoxifen, 100 nM; clemastine, 2 μM; ifenprodil, 2 μM; ketoconazole, 2.5 μM; amorolfine, 100 nM. Left, lanosterol; centre, zymostenol; right, 14-dehydrozymostenol. n = 2 wells per condition.
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S4075 |
Zinc PyrithioneZinc pyrithione (OM-1563) is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump. |
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S2536 |
MiconazoleMiconazole (Monistat) is an imidazole antifungal agent. |
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S1910 |
TioconazoleTioconazole (UK-20349) is an antifungal medication with an average IC50 of 1.7 μM. |
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S4120 |
Sulconazole NitrateSulconazole Nitrate is an imidazole derivative with broad-spectrum antifungal activity. |
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S3154 |
Butenafine HClButenafine HCl (KP-363) is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase. |
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S3156 |
Naftifine HClNaftifine is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis, probably involves selectively blocking sterol biosynthesis via inhibition of the squalene 2,3-epoxidase enzyme. |
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S1833 |
Butoconazole nitrateButoconazole nitrate (RS-35887) is an anti-fungal agent that inhibits PHA-stimulated release of cytokines-- IL-2, TNFα, IFN and GM-CSF from human peripheral blood lymphocytes (IC50 of 7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL and 7.6 μg/mL, respectively). |
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S4806 |
Potassium 1-NaphthaleneacetatePotassium 1-Naphthaleneacetate (KANU, α-Naphthaleneacetic Acid Potassium Salt) is being studied as a synthetic growth factor that affects conidial germination, sporulation, mycelial growth, cell surface morphology, and the viability of certain fungal plant pathogens. |
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S9200 |
Pneumocandin B0Pneumocandin B0 (L-688786) is a natural product and a key intermediate in the synthesis of the antifungal agent. |
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S0917 |
AllosecurininAllosecurinine (Phyllochrysine) is a Securinega alkaloid isolated from M.indica and M.discoidea with antifungal activity. |
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S6254 |
Hydrocinnamic acidHydrocinnamic acid (3-phenylpropionic acid, Benzylacetic acid) is a substrate of the enzyme oxidoreductases in the pathway phenylalanine metabolism (KEGG). It is an antifungal agent and a metabolite. |
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S4581 |
TriacetinTriacetin (Glycerol triacetate, Glyceryl triacetate, Glycerin triacetate, 1,2,3-Triacetoxypropane) is a triglyceride that is used as an antifungal agent. |
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S5553 |
Kasugamycin hydrochlorideKasugamycin is an aminoglycosidic antibiotic isolated from Streptomyces kasugaensis, showing broad-spectrum anti-fungal activity against yeast and various fungus species. |
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S0938 |
SakuranetinSakuranetin belongs to the group of methoxylated flavanones, with a widely bioactivity of antiproliferative against human cell lines typical for B16BL6 melanoma, esophageal squamous cell carcinoma (ESCC) and colon cancer (Colo 320), antiviral activity towards human rhinovirus 3 and influenza B virus, antioxidant, antimicrobial, antiinflammatory, antiparasitic, antimutagenic, and antiallergic properties. |
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S5944 |
ButenafineButenafine is a synthetic benzylamine antifungal agent. |
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S0832 |
DimboaDimboa (2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one) is an antifungal agent used in crops. |
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S5359 |
ButoconazoleButoconazole is an imidazole antifungal used in gynecology. |
![]() ![]() Percentage of MBP+ oligodendrocytes generated from OPCs following treatment with azoles (c). n ≥ 4 wells per condition.
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S8095 |
TubercidinTubercidin (7-deaza-adenosine), an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhibits antifungal and antiviral activities. |
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S3966 |
NifuratelNifuratel is a nitrofuran derivative with local antiprotozoal and antifungal activity and a broad spectrum of antibacterial action. |
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S3373 |
DeoxylapacholDeoxylapachol is a major cytotoxic component of New Zealand brown alga, Landsburgia quercifolia with antifungal and anti-cancer activity. |
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S3307 |
Galangin 3-methyl etherGalangin 3-methyl ether (3-O-Methylgalangin, 3-Methylgalangin), isolated from Lychnophora markgravii aerial parts, shows strong antibacterial and antifungal effects. |
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S4970 |
NerolNerol (Cis-Geraniol, Neryl alcohol) is a monoterpene found in many essential oils such as lemongrass and hops. |
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S3829 |
IsoalantolactoneIsoalantolactone, one of the major sesquiterpene lactone compounds, is isolated from the roots of Anula helenium and possesses multiple biological activities including antifungal, anthelmintic, antimicrobial, anti-inflammatory, antitrypanosomal activities and antiproliferative effects on several cancer cell lines, such as colon, melanoma, ovary, prostate, lung, and leukemia. |
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S2058 |
TolnaftateTolnaftate is a synthetic thiocarbamate used as an anti-fungal agent. |
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S4584 |
ButylparabenButylparaben (Butyl parahydroxybenzoate, Butyl 4-hydroxybenzoate) is a chemical compound commonly used as an antifungal preservative in cosmetic products. |
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S0770 |
CamalexinCamalexin, a phytoalexin isolated from Camelina sativa and Arabidopsis (Cruciferae), can induce reactive oxygen species (ROS) production. Camalexin has antibacterial, antifungal, antiproliferative and anticancer activities. |
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S0971 |
KakuolKakuol is a natural compound extracted from the rhizomes of Asarum sieboldii with antifungal activity. |
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S5080 |
NeticonazoleNeticonazole (SS717) is a selecvie inhibitor of exosome biogenesis and secretion. Neticonazole exhibits Neticonazole antifungal and antitumor activity. |
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S6118 |
Terpinen-4-olTerpinen-4-ol, a naturally occurring monoterpene, is the main bioactive component of tea-tree oil and has been shown to have many biological activities such as antifungal properties. |
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S4996 |
Tavaborole (AN-2690)Tavaborole (AN-2690) is a boron-containing small molecule with broad spectrum antifungal activity. |
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S5271 |
SuloctidilSuloctidil, a sulfur-containing aminoalcohol showing to inhibit human platelet aggregation, is a peripheral vasodilator and a potential antifungal agent. |
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S4755 |
lanosterolLanosterol is a tetracyclic triterpenoid and is the compound from which all animal and fungal steroids are derived. By contrast plant steroids are produced via cycloartenol. |
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S3532 |
AN-2718AN-2718, an inhibitor of fungal growth that blocks protein synthesis via the oxaborole tRNA trapping (OBORT) mechanism. |
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S3778 |
Patchouli alcoholPatchouli alcohol (Patchoulol, Patchouli camphor), an ingredient in pogostemonis herba, has various pharmacological activities and acts as an inhibitor of asexual fungal propagation, inflammation, the influenza virus, and tumorigenesis. |
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S4963 |
PurpurinPurpurin (1,2,4-Trihydroxyanthraquinone, Hydroxylizaric acid, Verantin) is one of the natural colorants extracted from madder roots and other Rubiaceae family plants. It exhibits anti-angiogenic, antifungal, antibiotic, and antioxidative activities. Purpurin strongly inhibits the activities of CYP1A1, CYP1A2 and CYP1B1. |
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S4178 |
ClimbazoleClimbazole is a broad-spectrum imidazole antifungal agent that can provide anti-dandruff benefits. |
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S3646 |
ThimerosalThimerosal (Thiomersalate, Mercurothiolate) is a well-established antiseptic and antifungal agent and usually used as a preservative in vaccines, immunoglobulin preparations, skin test antigens, antivenins, ophthalmic and nasal products, and tattoo inks. |
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S6270 |
2-Aminoisobutyric acid2-Aminoisobutyric acid (NSC-16590, 2-Methylalanine, H-Aib-OH) is a rare, non-protein amino acid and end-product of pyrimidine metabolism, excreted in urine and found in some antibiotics of fungal origin. |
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S4187 |
SalicylanilideSalicylanilides (WR10019) are a group of compounds with a wide range of biological activities including antiviral potency, antibacterial (including antimycobacterial) and antifungal activities. |
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S3676 |
CarbendazimCarbendazim (Mercarzole, Carbendazole) is a broad-spectrum systemic antimycotic and can be used to control a broad range of diseases on field crops, fruits, and vegetables, including sclerotinia rot of canola, wheat head blight, peanut leaf spot, and SB on rice. Its mode of action is to inhibit the formation of mitotic microtubules in of fungi. |
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S4258 |
LuliconazoleLuliconazole is a broad-spectrum antifungal drug. |
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S9350 |
Ethyl 4-MethoxycinnamateEthyl 4-Methoxycinnamate (Ethyl p-methoxycinnamate, 4-Methoxycinnamic Acid Ethyl Ester), a natural product found in K. galanga and C. zedoaria extracts, has anti-inflammatory, antiangiogenic, antifungal, larvicidal, and analgesic activities. |
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S9057 |
SinigrinSinigrin (Allylglucosinolate, 2-Propenylglucosinolate) is a glucosinolate found in some plants of the Brassicaceae family and exerts various activities including anticancer, anti-inflammatory, antibacterial, antifungal, antioxidant, and wound healing effects. |
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S2534 |
Isoconazole nitrateIsoconazole nitrate (Travogen) is an azole antifungal reagent. |
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S5704 |
MyclobutanilMyclobutanil is a widely used triazole fungicide and also a steroid demethylation inhibitor. |
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S3705 |
ChlorobutanolChlorobutanol (Chlorbutol, Chloreton, Chloretone, Chlortran|, trichloro-2-methyl-2-propanol) is a preservative, sedative, hypnotic and weak local anesthetic with antibacterial and antifungal properties. |
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S3860 |
AllicinAllicin (Diallyl Thiosulfinate), the main biologically active component of the freshly crushed garlic extracts, possesses various biological activities including antibacterial, antifungal and antiparasitic effects. |
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S9072 |
SwerosideSweroside, a bioactive herbal ingredient isolated from Fructus Corni, exhibits diverse biological activities, such as anti-fungal, anti-diabetic, anti-inflammatory, and anti-tumor effects. |
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S2321 |
MagnololMagnolol (NSC 293099) is a bioactive lignin found in the bark of the Houpu magnolia (Magnolia officinalis) which shows antifungal properties. It can block TNF-α-induced NF-KB activation. |
![]() ![]() Magnolol reduces RNV areas and avascular areas in OIR mice. Mice retinas from OIR group (a, b) and OIR + Magnolol (25 mg/kg) group (c, d) were harvested at P17 and subjected to wholemount immunostaining with IB4 (red), showing neovascular areas (green) and avascular areas (yellow).
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S6408 |
HexetidineHexetidine is an anti-bacterial and anti-fungal agent with local anesthetic, astringent, deodorant and antiplaque activity. |
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S5033 |
TerconazoleTerconazole (Terazol 3, Terazol 7, Triaconazole, Gyno-Terazol) is a new, broad-spectrum, triazole antifungal agent which is primarily used to treat vaginal fungal infections. |
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S5025 |
EfinaconazoleEfinaconazole (KP-103) is an inhibitor of 14 alpha-demethylase which is involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes. |
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S3588 |
Hexylene glycolHexylene glycol (HG, 2-Methyl-2,4-pentanediol, MPD) is an oxygenated solvent derived from acetone that has been used widely in industrial chemicals and cosmetics. Hexylene glycol exhibits antibacterial and antifungal properties. |
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S3595 |
D-Gluconic acidD-Gluconic acid is an antifungal agent. |
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S9413 |
YangoninYangonin (Y100550) is a dienolide kavalactone originally found in Piper methysticum (kava plant) and exhibits neuroprotective, neuromodulatory, and antifungal activities. It activates cannabinoid (CB1) receptors and potentiates the effects of GABA-A receptors. |
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S5724 |
DichlorophenDichlorophen (Dichlorophene, Bis(5-chloro-2-hydroxyphenyl)methane) is an anticestodal agent, fungicide, germicide, and antimicrobial agent. |
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S5829 |
MonomyristinMonomyristin (Glyceryl myristate, 2,3-Dihydroxypropyl tetradecanoate), a monoacylglyceride, shows high antibacterial and antifungal activities. |
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S4601 |
ClioquinolClioquinol (Iodochlorhydroxyquin, Chinoform) is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities. |
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S6451 |
SalifunginSalifungin (Multifungin, Bromosalicylchloranilide) is an antifungal and may cause allergic contact dermatitis in some individuals. |
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S3722 |
IsavuconazoleIsavuconazole (BAL-4815, RO-0094815) is a new extended-spectrum triazole with activity against yeasts, molds, and dimorphic fungi that inhibits cytochrome P450 (CYP)-dependent 14α-lanosterol demethylation, which is essential for fungal cell membrane ergosterol synthesis. |
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S5541 |
DimetridazoleDimetridazole is an anti-fungal and anti-protozoal used for the control of infection in pigs, poultry, turkeys, game birds, pigeons and other caged birds. |
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S3979 |
Zinc UndecylenateZinc Undecylenate (Zinc diundec-10-enoate, Zinc 10-undecenoate) is a natural or synthetic fungistatic fatty acid, antifungal Zinc Undecylenate is used topically in creams against fungal infections, eczemas, ringworm, and other cutaneous conditions. |
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S5086 |
p-Anisaldehydep-Anisaldehyde (4-Methoxybenzaldehyde, Anisaldehyde, Anisic aldehyde, P-Methoxybenzaldehyde, 4-Anisaldehyde), an extract from Pimpinella anisum seeds, exhibits antifungal activity against a number of yeast and mold strains in laboratory media, fruit purees and fruit juices. |
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S6467 |
FosfluconazoleFosfluconazole is a water-soluble phosphate prodrug of fluconazole, which is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections. |
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S9444 |
TomatineTomatine (Lycopersicin) is a natural glycoalkaloid with fungicidal, antimicrobial, and insecticidal properties. |
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S4525 |
EthylparabenEthylparaben (Ethyl parahydroxybenzoate, Ethyl 4-hydroxybenzoate) is the ethyl ester of p-hydroxybenzoic acid, used as an antifungal preservative and food additive. It is a standardized chemical allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. |
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S4878 |
Neticonazole HydrochlorideNeticonazole is an imidazole antifungal for the treatment of fungal skin infections. |
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S5845 |
ChalconeChalcone (benzylideneacetophenone, phenyl styryl ketone, benzalacetophenone, β-phenylacrylophenone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones with antibacterial, antifungal, antitumor and anti-inflammatory properties. |
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S4793 |
Cedryl acetateCedryl Acetate (Cedrol acetate, Cedranyl acetate), an acetylated from cedarwood oil, has been applied to chemistry for its properties as a chiral and cell signaling reagent with antifungal and immunotoxicity functions. Cedryl acetate exhibits α-glucosidase inhibitory activity. |
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S5512 |
JugloneJuglone (Regianin, 5-Hydroxy-1,4-naphthoquinone), a natural naphthoquinone found in the black walnut and other plants, has moderate antifungal activity and growth-stimulating effects to many types of plants. It sometimes can be used as an herbicide, as a dye for cloth and inks, and as a coloring agent for foods and cosmetics. |
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S4516 |
(+)-CamphorCamphor is a waxy, flammable, white or transparent solid with a strong aroma, often used to relieve pain, reduce itching and treat fungal infections. It can activate TRPV1 and TRPV3. |
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S5373 |
Pseudolaric Acid BPseudolaric Acid B, a natural diterpenoid compound isolated from the root and trunk bark of Pseudolaric kaempferi Gordon, has anti-fungal and anti-fertility properties. |
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S4843 |
Potassium acetatePotassium acetate (Diuretic salt, Potassium ethanoate) is the potassium salt of acetic acid, which is a synthetic carboxylic acid with antibacterial and antifungal properties. |
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S4286 |
Anidulafungin (LY303366)Anidulafungin (LY303366), an echinocandin derivative, inhibits glucan synthase activity, used as an antifungal drug. |
![]() ![]() Effect of Anidulafungin on hemolysis. Arithmetic means ± SEM (n = 8) of the percentage of hemolytic erythrocytes following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Anidulafungin (1.5-6 μg/ml). ***(p<0.001) indicates significant difference from the absence of Anidulafungin (ANOVA).
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S3910 |
4',7-Dimethoxyisoflavone4',7-Dimethoxyisoflavone, isolated from the leaves of Albizzia lebbeck, shows antifungal activity in vitro. |
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S4287 |
Micafungin (FK 463) SodiumMicafungin Sodium (FK463, Mycamine) is an inhibitor of 1, 3-beta-D-glucan synthesis, used as an antifungal drug. |
![]() ![]() Effect of Micafungin on erythrocyte forward scatter. A. Original histogram of forward scatter of erythrocytes following exposure for 48 hours to Ringer solution without (grey area) and with (black line) presense of 25 µg/ml Micafungin. B. Arithmetic means ± SEM (n = 14) of the erythrocyte forward scatter (FSC) following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Micafungin (10-25 µg/ml). C. Arithmetic means ± SEM (n = 14) of the percentage of erythrocytes with forward scatter(FSC) <200 following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Micafungin (10-25 µg/ml). D. Arithmetic means ± SEM (n = 14) of the percentage of erythrocytes with forward scatter (FSC) >800 following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Micafungin (10-25 µg/ml). ***(p<0.001) indicates significant difference from the absence of Micafungin (ANOVA).
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S4559 |
CloxiquineCloxiquine (5-Chloro-8-quinolinol, Dermofungin) is an antibacterial, antifungal, antiaging and antituberculosis drug. |
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S3985 |
Methyl 4-hydroxybenzoateMethyl 4-hydroxybenzoate (Methylparaben, Methyl p-hydroxybenzoate, Nipagin) is an anti-fungal agent often used in a variety of cosmetics, personal-care products and food preservatives. |
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S0491 |
Manogepix (E1210)Manogepix (E1210, MGX, APX001A) is a broad-spectrum and orally active antifungal agent that inhibits Gwt1/Gwt1p (GPI-anchored wall transfer protein 1), a protein that plays an important role in fungal cell wall integrity. |
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S3990 |
Trans-AnetholeTrans-anethole (4-Propenylanisole) is a phenylpropene derivative found in many essential oils, including anise oil. It has neuromodulatory, anxiolytic, antioxidative, antifungal, anti-inflammatory, and immunomodulatory activities. |
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S1442 |
Voriconazole (UK-109496)Voriconazole (UK-109496) is a new triazole derivative similar to fluconazole and itraconazole that acts by inhibiting fungal cytochrome P-450-dependent, 14-alpha-sterol demethylase-mediated synthesis of ergosterol. |
![]() ![]() Voriconazole increases the osteogenic activity of human osteoblasts in vitro. Osteoblasts were exposed to voriconazole (VCZ) or fluconazole (FCZ) at 15 or 200 μg/ml in osteoinductive medium (OS+) for up to 7 days. As a positive control, cells were also exposed to sodium fluoride (NaF) at 10 μM in nonosteoinductive medium (OS−). Osteoblastic differentiation was evaluated by measuring alkaline phosphatase (ALP) activity (A) and staining for calcium deposition with alazarin red S stain (B and C); calcium deposition was quantified by measuring the absorbance (A415) of extracted alazarin red S (B) and was assessed by the light microscopic appearance (white arrows) of stained osteoblast cultures (C). Values represent the means ± SD. *, P < 0.05, compared to osteoblasts grown under osteogenic conditions without treatment. |
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S5174 |
Kojic acidKojic acid is a fungal metabolite that inhibits tyrosinase with an IC50 value of 30.6 µM for mushroom tyrosinase. It is a synthetic intermediate used for production of food additives. |
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S5083 |
LentinanLentinan (A823605, Bromoduline), isolated and purified from a hot water extract of Lentinula edodes fruit bodies, is a fungal polysaccharide immunomodulator with anti-tumor effects. |
製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
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S1517 |
NatamycinNatamycin (Pimaricin), a natural and versatile anti-fungal agent during fermentation by the bacterium Streptomyces natalensis, commonly found in soil; with little to no flavour interference |
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S2476 |
Itraconazole (R 51211)Itraconazole (R 51211) is a relatively potent inhibitor of CYP3A4 with IC50 of 6.1 nM, used as a triazole antifungal agent. Itraconazole is a potent antagonist of the Hedgehog (Hh) signaling pathway. Itraconazole suppresses the growth of glioblastoma through induction of autophagy. |
![]() ![]() Resistance to itraconazole in MA cells. The parental SUM149-Luc cell line and MA1 cells were treated in parallel with 1 mM itraconazole for 9 days (which killed most of the cells in the parental cell line) and were allowed to recover and grow in a drug-free medium for 5 days before being stained. Since itraconazole was ineffective in killing MA1 cells, the cells grew into a continuous monolayer rather than colonies. |
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S1331 |
Fluconazole (UK 49858)Fluconazole (UK 49858) is a fungal lanosterol 14 alpha-demethylase inhibitor, which thereby prevents the formation of ergosterol,used in the treatment and prevention of superficial and systemic fungal infections. |
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S1934 |
Nystatin (Fungicidin)Nystatin, which belongs to the polyene group of antimycotics, is frequently used as a topical agent in the treatment of oro-pharyngeal candidosis. |
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S1725 |
TerbinafineTerbinafine (SF 86-327) is used to treat infections caused by a fungus. It works by killing the fungus or preventing its growth. |
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S1606 |
ClotrimazoleClotrimazole (BAY b 5097, FB 5097) alters the permeability of the fungal cell wall by inhibiting the biosynthesis of ergosterol, used in the treatment of fungal infections. |
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S1956 |
Miconazole NitrateMiconazole (NSC 169434) Nitrate is an imidazole antifungal agent by inhibiting ergosterol biosynthesis and inducing ROS, used to treat vaginal yeast infections. |
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S1666 |
FlucytosineFlucytosine (5-Fluorocytosine, 5-FC, NSC 103805, Ro 2-9915) is an antifungal drug with IC50 of 0.93 μM in C. albicans. |
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S2557 |
Terbinafine HClTerbinafine HCl (KWD 201) inhibits ergosterol synthesis by inhibiting squalene epoxidase, used as an antifungal drug. |
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S3073 |
Caspofungin (MK-0991) AcetateCaspofungin Acetate (MK-0991, L-743872) is an lipopeptide antifungal β-1,3-glucan synthase inhibitor. |
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S2528 |
CiclopiroxCiclopirox is a broad-spectrum antifungal agent working as an iron chelator. |
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S3019 |
Ciclopirox ethanolamineCiclopirox ethanolamine (Ciclopirox olamine, HOE 296) is a broad-spectrum antifungal agent working as an iron chelator. |
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S2535 |
Econazole nitrateEconazole Nitrate (NSC 243115) is a Ca2+ channel blocker, used as an antifungal medicine that fights infections caused by fungus. |
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S1854 |
BifonazoleBifonazole (Bay h 4502) is a substituted imidazole antifungal agent. |
![]() ![]() Percentage of MBP+ oligodendrocytes generated from OPCs following treatment with azoles (c). n ≥ 4 wells per condition.
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S3079 |
AtovaquoneAtovaquone (Atavaquone) is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia. |
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S1997 |
LiranaftateLiranaftate is a squalene epoxidase inhibitor with anti-fungicidal activities. |
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S3161 |
Sertaconazole nitrateSertaconazole nitrate (FI-7045) is a topical broad-spectrum antifungal that is developed to provide an additional agent for the treatment of superficial cutaneous and mucosal infections. |
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S2031 |
Fenticonazole NitrateFenticonazole Nitrate is an azole antifungal agent. |
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S1676 |
Amorolfine HClAmorolfine HCl is an antifungal reagent. |
![]() ![]() b, GC–MS-based quantification of three metabolite levels in human glioma cells (GBM528) treated for 24 h with the indicated small molecules at the following concentrations: tamoxifen, 100 nM; clemastine, 2 μM; ifenprodil, 2 μM; ketoconazole, 2.5 μM; amorolfine, 100 nM. Left, lanosterol; centre, zymostenol; right, 14-dehydrozymostenol. n = 2 wells per condition.
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S4075 |
Zinc PyrithioneZinc pyrithione (OM-1563) is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump. |
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S2536 |
MiconazoleMiconazole (Monistat) is an imidazole antifungal agent. |
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S1910 |
TioconazoleTioconazole (UK-20349) is an antifungal medication with an average IC50 of 1.7 μM. |
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S4120 |
Sulconazole NitrateSulconazole Nitrate is an imidazole derivative with broad-spectrum antifungal activity. |
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S3154 |
Butenafine HClButenafine HCl (KP-363) is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase. |
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S3156 |
Naftifine HClNaftifine is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis, probably involves selectively blocking sterol biosynthesis via inhibition of the squalene 2,3-epoxidase enzyme. |
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S1833 |
Butoconazole nitrateButoconazole nitrate (RS-35887) is an anti-fungal agent that inhibits PHA-stimulated release of cytokines-- IL-2, TNFα, IFN and GM-CSF from human peripheral blood lymphocytes (IC50 of 7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL and 7.6 μg/mL, respectively). |
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S4806 |
Potassium 1-NaphthaleneacetatePotassium 1-Naphthaleneacetate (KANU, α-Naphthaleneacetic Acid Potassium Salt) is being studied as a synthetic growth factor that affects conidial germination, sporulation, mycelial growth, cell surface morphology, and the viability of certain fungal plant pathogens. |
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S9200 |
Pneumocandin B0Pneumocandin B0 (L-688786) is a natural product and a key intermediate in the synthesis of the antifungal agent. |
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S0917 |
AllosecurininAllosecurinine (Phyllochrysine) is a Securinega alkaloid isolated from M.indica and M.discoidea with antifungal activity. |
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S6254 |
Hydrocinnamic acidHydrocinnamic acid (3-phenylpropionic acid, Benzylacetic acid) is a substrate of the enzyme oxidoreductases in the pathway phenylalanine metabolism (KEGG). It is an antifungal agent and a metabolite. |
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S4581 |
TriacetinTriacetin (Glycerol triacetate, Glyceryl triacetate, Glycerin triacetate, 1,2,3-Triacetoxypropane) is a triglyceride that is used as an antifungal agent. |
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S5553 |
Kasugamycin hydrochlorideKasugamycin is an aminoglycosidic antibiotic isolated from Streptomyces kasugaensis, showing broad-spectrum anti-fungal activity against yeast and various fungus species. |
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S0938 |
SakuranetinSakuranetin belongs to the group of methoxylated flavanones, with a widely bioactivity of antiproliferative against human cell lines typical for B16BL6 melanoma, esophageal squamous cell carcinoma (ESCC) and colon cancer (Colo 320), antiviral activity towards human rhinovirus 3 and influenza B virus, antioxidant, antimicrobial, antiinflammatory, antiparasitic, antimutagenic, and antiallergic properties. |
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S5944 |
ButenafineButenafine is a synthetic benzylamine antifungal agent. |
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S0832 |
DimboaDimboa (2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one) is an antifungal agent used in crops. |
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S5359 |
ButoconazoleButoconazole is an imidazole antifungal used in gynecology. |
![]() ![]() Percentage of MBP+ oligodendrocytes generated from OPCs following treatment with azoles (c). n ≥ 4 wells per condition.
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S8095 |
TubercidinTubercidin (7-deaza-adenosine), an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhibits antifungal and antiviral activities. |
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S3966 |
NifuratelNifuratel is a nitrofuran derivative with local antiprotozoal and antifungal activity and a broad spectrum of antibacterial action. |
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S3373 |
DeoxylapacholDeoxylapachol is a major cytotoxic component of New Zealand brown alga, Landsburgia quercifolia with antifungal and anti-cancer activity. |
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S3307 |
Galangin 3-methyl etherGalangin 3-methyl ether (3-O-Methylgalangin, 3-Methylgalangin), isolated from Lychnophora markgravii aerial parts, shows strong antibacterial and antifungal effects. |
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S4970 |
NerolNerol (Cis-Geraniol, Neryl alcohol) is a monoterpene found in many essential oils such as lemongrass and hops. |
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S3829 |
IsoalantolactoneIsoalantolactone, one of the major sesquiterpene lactone compounds, is isolated from the roots of Anula helenium and possesses multiple biological activities including antifungal, anthelmintic, antimicrobial, anti-inflammatory, antitrypanosomal activities and antiproliferative effects on several cancer cell lines, such as colon, melanoma, ovary, prostate, lung, and leukemia. |
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S2058 |
TolnaftateTolnaftate is a synthetic thiocarbamate used as an anti-fungal agent. |
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S4584 |
ButylparabenButylparaben (Butyl parahydroxybenzoate, Butyl 4-hydroxybenzoate) is a chemical compound commonly used as an antifungal preservative in cosmetic products. |
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S0770 |
CamalexinCamalexin, a phytoalexin isolated from Camelina sativa and Arabidopsis (Cruciferae), can induce reactive oxygen species (ROS) production. Camalexin has antibacterial, antifungal, antiproliferative and anticancer activities. |
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S0971 |
KakuolKakuol is a natural compound extracted from the rhizomes of Asarum sieboldii with antifungal activity. |
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S5080 |
NeticonazoleNeticonazole (SS717) is a selecvie inhibitor of exosome biogenesis and secretion. Neticonazole exhibits Neticonazole antifungal and antitumor activity. |
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S6118 |
Terpinen-4-olTerpinen-4-ol, a naturally occurring monoterpene, is the main bioactive component of tea-tree oil and has been shown to have many biological activities such as antifungal properties. |
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S4996 |
Tavaborole (AN-2690)Tavaborole (AN-2690) is a boron-containing small molecule with broad spectrum antifungal activity. |
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S5271 |
SuloctidilSuloctidil, a sulfur-containing aminoalcohol showing to inhibit human platelet aggregation, is a peripheral vasodilator and a potential antifungal agent. |
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S4755 |
lanosterolLanosterol is a tetracyclic triterpenoid and is the compound from which all animal and fungal steroids are derived. By contrast plant steroids are produced via cycloartenol. |
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S3532 |
AN-2718AN-2718, an inhibitor of fungal growth that blocks protein synthesis via the oxaborole tRNA trapping (OBORT) mechanism. |
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S3778 |
Patchouli alcoholPatchouli alcohol (Patchoulol, Patchouli camphor), an ingredient in pogostemonis herba, has various pharmacological activities and acts as an inhibitor of asexual fungal propagation, inflammation, the influenza virus, and tumorigenesis. |
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S4963 |
PurpurinPurpurin (1,2,4-Trihydroxyanthraquinone, Hydroxylizaric acid, Verantin) is one of the natural colorants extracted from madder roots and other Rubiaceae family plants. It exhibits anti-angiogenic, antifungal, antibiotic, and antioxidative activities. Purpurin strongly inhibits the activities of CYP1A1, CYP1A2 and CYP1B1. |
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S4178 |
ClimbazoleClimbazole is a broad-spectrum imidazole antifungal agent that can provide anti-dandruff benefits. |
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S3646 |
ThimerosalThimerosal (Thiomersalate, Mercurothiolate) is a well-established antiseptic and antifungal agent and usually used as a preservative in vaccines, immunoglobulin preparations, skin test antigens, antivenins, ophthalmic and nasal products, and tattoo inks. |
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S6270 |
2-Aminoisobutyric acid2-Aminoisobutyric acid (NSC-16590, 2-Methylalanine, H-Aib-OH) is a rare, non-protein amino acid and end-product of pyrimidine metabolism, excreted in urine and found in some antibiotics of fungal origin. |
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S4187 |
SalicylanilideSalicylanilides (WR10019) are a group of compounds with a wide range of biological activities including antiviral potency, antibacterial (including antimycobacterial) and antifungal activities. |
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S3676 |
CarbendazimCarbendazim (Mercarzole, Carbendazole) is a broad-spectrum systemic antimycotic and can be used to control a broad range of diseases on field crops, fruits, and vegetables, including sclerotinia rot of canola, wheat head blight, peanut leaf spot, and SB on rice. Its mode of action is to inhibit the formation of mitotic microtubules in of fungi. |
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S4258 |
LuliconazoleLuliconazole is a broad-spectrum antifungal drug. |
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S9350 |
Ethyl 4-MethoxycinnamateEthyl 4-Methoxycinnamate (Ethyl p-methoxycinnamate, 4-Methoxycinnamic Acid Ethyl Ester), a natural product found in K. galanga and C. zedoaria extracts, has anti-inflammatory, antiangiogenic, antifungal, larvicidal, and analgesic activities. |
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S9057 |
SinigrinSinigrin (Allylglucosinolate, 2-Propenylglucosinolate) is a glucosinolate found in some plants of the Brassicaceae family and exerts various activities including anticancer, anti-inflammatory, antibacterial, antifungal, antioxidant, and wound healing effects. |
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S2534 |
Isoconazole nitrateIsoconazole nitrate (Travogen) is an azole antifungal reagent. |
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S5704 |
MyclobutanilMyclobutanil is a widely used triazole fungicide and also a steroid demethylation inhibitor. |
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S3705 |
ChlorobutanolChlorobutanol (Chlorbutol, Chloreton, Chloretone, Chlortran|, trichloro-2-methyl-2-propanol) is a preservative, sedative, hypnotic and weak local anesthetic with antibacterial and antifungal properties. |
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S3860 |
AllicinAllicin (Diallyl Thiosulfinate), the main biologically active component of the freshly crushed garlic extracts, possesses various biological activities including antibacterial, antifungal and antiparasitic effects. |
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S9072 |
SwerosideSweroside, a bioactive herbal ingredient isolated from Fructus Corni, exhibits diverse biological activities, such as anti-fungal, anti-diabetic, anti-inflammatory, and anti-tumor effects. |
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S2321 |
MagnololMagnolol (NSC 293099) is a bioactive lignin found in the bark of the Houpu magnolia (Magnolia officinalis) which shows antifungal properties. It can block TNF-α-induced NF-KB activation. |
![]() ![]() Magnolol reduces RNV areas and avascular areas in OIR mice. Mice retinas from OIR group (a, b) and OIR + Magnolol (25 mg/kg) group (c, d) were harvested at P17 and subjected to wholemount immunostaining with IB4 (red), showing neovascular areas (green) and avascular areas (yellow).
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S6408 |
HexetidineHexetidine is an anti-bacterial and anti-fungal agent with local anesthetic, astringent, deodorant and antiplaque activity. |
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S5033 |
TerconazoleTerconazole (Terazol 3, Terazol 7, Triaconazole, Gyno-Terazol) is a new, broad-spectrum, triazole antifungal agent which is primarily used to treat vaginal fungal infections. |
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S5025 |
EfinaconazoleEfinaconazole (KP-103) is an inhibitor of 14 alpha-demethylase which is involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes. |
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S3588 |
Hexylene glycolHexylene glycol (HG, 2-Methyl-2,4-pentanediol, MPD) is an oxygenated solvent derived from acetone that has been used widely in industrial chemicals and cosmetics. Hexylene glycol exhibits antibacterial and antifungal properties. |
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S3595 |
D-Gluconic acidD-Gluconic acid is an antifungal agent. |
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S9413 |
YangoninYangonin (Y100550) is a dienolide kavalactone originally found in Piper methysticum (kava plant) and exhibits neuroprotective, neuromodulatory, and antifungal activities. It activates cannabinoid (CB1) receptors and potentiates the effects of GABA-A receptors. |
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S5724 |
DichlorophenDichlorophen (Dichlorophene, Bis(5-chloro-2-hydroxyphenyl)methane) is an anticestodal agent, fungicide, germicide, and antimicrobial agent. |
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S5829 |
MonomyristinMonomyristin (Glyceryl myristate, 2,3-Dihydroxypropyl tetradecanoate), a monoacylglyceride, shows high antibacterial and antifungal activities. |
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S4601 |
ClioquinolClioquinol (Iodochlorhydroxyquin, Chinoform) is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities. |
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S6451 |
SalifunginSalifungin (Multifungin, Bromosalicylchloranilide) is an antifungal and may cause allergic contact dermatitis in some individuals. |
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S3722 |
IsavuconazoleIsavuconazole (BAL-4815, RO-0094815) is a new extended-spectrum triazole with activity against yeasts, molds, and dimorphic fungi that inhibits cytochrome P450 (CYP)-dependent 14α-lanosterol demethylation, which is essential for fungal cell membrane ergosterol synthesis. |
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S5541 |
DimetridazoleDimetridazole is an anti-fungal and anti-protozoal used for the control of infection in pigs, poultry, turkeys, game birds, pigeons and other caged birds. |
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S3979 |
Zinc UndecylenateZinc Undecylenate (Zinc diundec-10-enoate, Zinc 10-undecenoate) is a natural or synthetic fungistatic fatty acid, antifungal Zinc Undecylenate is used topically in creams against fungal infections, eczemas, ringworm, and other cutaneous conditions. |
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S5086 |
p-Anisaldehydep-Anisaldehyde (4-Methoxybenzaldehyde, Anisaldehyde, Anisic aldehyde, P-Methoxybenzaldehyde, 4-Anisaldehyde), an extract from Pimpinella anisum seeds, exhibits antifungal activity against a number of yeast and mold strains in laboratory media, fruit purees and fruit juices. |
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S6467 |
FosfluconazoleFosfluconazole is a water-soluble phosphate prodrug of fluconazole, which is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections. |
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S9444 |
TomatineTomatine (Lycopersicin) is a natural glycoalkaloid with fungicidal, antimicrobial, and insecticidal properties. |
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S4525 |
EthylparabenEthylparaben (Ethyl parahydroxybenzoate, Ethyl 4-hydroxybenzoate) is the ethyl ester of p-hydroxybenzoic acid, used as an antifungal preservative and food additive. It is a standardized chemical allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. |
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S4878 |
Neticonazole HydrochlorideNeticonazole is an imidazole antifungal for the treatment of fungal skin infections. |
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S5845 |
ChalconeChalcone (benzylideneacetophenone, phenyl styryl ketone, benzalacetophenone, β-phenylacrylophenone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones with antibacterial, antifungal, antitumor and anti-inflammatory properties. |
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S4793 |
Cedryl acetateCedryl Acetate (Cedrol acetate, Cedranyl acetate), an acetylated from cedarwood oil, has been applied to chemistry for its properties as a chiral and cell signaling reagent with antifungal and immunotoxicity functions. Cedryl acetate exhibits α-glucosidase inhibitory activity. |
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S5512 |
JugloneJuglone (Regianin, 5-Hydroxy-1,4-naphthoquinone), a natural naphthoquinone found in the black walnut and other plants, has moderate antifungal activity and growth-stimulating effects to many types of plants. It sometimes can be used as an herbicide, as a dye for cloth and inks, and as a coloring agent for foods and cosmetics. |
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S4516 |
(+)-CamphorCamphor is a waxy, flammable, white or transparent solid with a strong aroma, often used to relieve pain, reduce itching and treat fungal infections. It can activate TRPV1 and TRPV3. |
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S5373 |
Pseudolaric Acid BPseudolaric Acid B, a natural diterpenoid compound isolated from the root and trunk bark of Pseudolaric kaempferi Gordon, has anti-fungal and anti-fertility properties. |
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S4843 |
Potassium acetatePotassium acetate (Diuretic salt, Potassium ethanoate) is the potassium salt of acetic acid, which is a synthetic carboxylic acid with antibacterial and antifungal properties. |
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S4286 |
Anidulafungin (LY303366)Anidulafungin (LY303366), an echinocandin derivative, inhibits glucan synthase activity, used as an antifungal drug. |
![]() ![]() Effect of Anidulafungin on hemolysis. Arithmetic means ± SEM (n = 8) of the percentage of hemolytic erythrocytes following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Anidulafungin (1.5-6 μg/ml). ***(p<0.001) indicates significant difference from the absence of Anidulafungin (ANOVA).
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S3910 |
4',7-Dimethoxyisoflavone4',7-Dimethoxyisoflavone, isolated from the leaves of Albizzia lebbeck, shows antifungal activity in vitro. |
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S4287 |
Micafungin (FK 463) SodiumMicafungin Sodium (FK463, Mycamine) is an inhibitor of 1, 3-beta-D-glucan synthesis, used as an antifungal drug. |
![]() ![]() Effect of Micafungin on erythrocyte forward scatter. A. Original histogram of forward scatter of erythrocytes following exposure for 48 hours to Ringer solution without (grey area) and with (black line) presense of 25 µg/ml Micafungin. B. Arithmetic means ± SEM (n = 14) of the erythrocyte forward scatter (FSC) following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Micafungin (10-25 µg/ml). C. Arithmetic means ± SEM (n = 14) of the percentage of erythrocytes with forward scatter(FSC) <200 following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Micafungin (10-25 µg/ml). D. Arithmetic means ± SEM (n = 14) of the percentage of erythrocytes with forward scatter (FSC) >800 following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Micafungin (10-25 µg/ml). ***(p<0.001) indicates significant difference from the absence of Micafungin (ANOVA).
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S4559 |
CloxiquineCloxiquine (5-Chloro-8-quinolinol, Dermofungin) is an antibacterial, antifungal, antiaging and antituberculosis drug. |
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S3985 |
Methyl 4-hydroxybenzoateMethyl 4-hydroxybenzoate (Methylparaben, Methyl p-hydroxybenzoate, Nipagin) is an anti-fungal agent often used in a variety of cosmetics, personal-care products and food preservatives. |
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S0491 |
Manogepix (E1210)Manogepix (E1210, MGX, APX001A) is a broad-spectrum and orally active antifungal agent that inhibits Gwt1/Gwt1p (GPI-anchored wall transfer protein 1), a protein that plays an important role in fungal cell wall integrity. |
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S3990 |
Trans-AnetholeTrans-anethole (4-Propenylanisole) is a phenylpropene derivative found in many essential oils, including anise oil. It has neuromodulatory, anxiolytic, antioxidative, antifungal, anti-inflammatory, and immunomodulatory activities. |
製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
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S1442 |
Voriconazole (UK-109496)Voriconazole (UK-109496) is a new triazole derivative similar to fluconazole and itraconazole that acts by inhibiting fungal cytochrome P-450-dependent, 14-alpha-sterol demethylase-mediated synthesis of ergosterol. |
2022, 10(1):e0200721 2022, 22(1):21 2021, 12:649026 |
![]() ![]() Voriconazole increases the osteogenic activity of human osteoblasts in vitro. Osteoblasts were exposed to voriconazole (VCZ) or fluconazole (FCZ) at 15 or 200 μg/ml in osteoinductive medium (OS+) for up to 7 days. As a positive control, cells were also exposed to sodium fluoride (NaF) at 10 μM in nonosteoinductive medium (OS−). Osteoblastic differentiation was evaluated by measuring alkaline phosphatase (ALP) activity (A) and staining for calcium deposition with alazarin red S stain (B and C); calcium deposition was quantified by measuring the absorbance (A415) of extracted alazarin red S (B) and was assessed by the light microscopic appearance (white arrows) of stained osteoblast cultures (C). Values represent the means ± SD. *, P < 0.05, compared to osteoblasts grown under osteogenic conditions without treatment. |
S5174 |
Kojic acidKojic acid is a fungal metabolite that inhibits tyrosinase with an IC50 value of 30.6 µM for mushroom tyrosinase. It is a synthetic intermediate used for production of food additives. |
2017, 18(9) |
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S5083 |
LentinanLentinan (A823605, Bromoduline), isolated and purified from a hot water extract of Lentinula edodes fruit bodies, is a fungal polysaccharide immunomodulator with anti-tumor effects. |