Fungal

阻害剤の選択性比較

カタログ番号	製品カタログ	溶解度(25°C)
カタログ番号	製品カタログ	水	DMSO	アルコール
S1517	Natamycin	<1 mg/mL	7 mg/mL	'<1 mg/mL
S2476	Itraconazole (R 51211)	<1 mg/mL	7 mg/mL	'''<1 mg/mL
S1331	Fluconazole (UK 49858)	<1 mg/mL	61 mg/mL	''61 mg/mL
S1934	Nystatin (Fungicidin)	<1 mg/mL	19 mg/mL	<1 mg/mL
S5080	Neticonazole	60 mg/mL	60 mg/mL	''60 mg/mL
S3588	Hexylene glycol			' mg/mL
S3595	D-Gluconic acid			' mg/mL
S3532	AN-2718			' mg/mL
S0938	Sakuranetin			' mg/mL
S0832	Dimboa			' mg/mL
S0971	Kakuol			' mg/mL
S3373	Deoxylapachol			' mg/mL
S3307	Galangin 3-methyl ether	-1 mg/mL	100 mg/mL	-1 mg/mL
S0917	Allosecurinin	-1 mg/mL	100 mg/mL	-1 mg/mL
S1725	Terbinafine	<1 mg/mL	58 mg/mL	'58 mg/mL
S1606	Clotrimazole	<1 mg/mL	11 mg/mL	'69 mg/mL
S1956	Miconazole Nitrate	<1 mg/mL	96 mg/mL	'1 mg/mL
S1666	Flucytosine	5 mg/mL	8 mg/mL	''<1 mg/mL
S2557	Terbinafine HCl	<1 mg/mL	66 mg/mL	'66 mg/mL
S3073	Caspofungin (MK-0991) Acetate	100 mg/mL	-1 mg/mL	'''-1 mg/mL
S2528	Ciclopirox	<1 mg/mL	42 mg/mL	'42 mg/mL
S3019	Ciclopirox ethanolamine	<1 mg/mL	6 mg/mL	'30 mg/mL
S2535	Econazole nitrate	<1 mg/mL	89 mg/mL	''5 mg/mL
S1854	Bifonazole	<1 mg/mL	62 mg/mL	'20 mg/mL
S3079	Atovaquone	<1 mg/mL	5 mg/mL	'<1 mg/mL
S1997	Liranaftate	<1 mg/mL	<1 mg/mL	''<1 mg/mL
S3161	Sertaconazole nitrate	<1 mg/mL	100 mg/mL	'<1 mg/mL
S2031	Fenticonazole Nitrate	<1 mg/mL	104 mg/mL	'2 mg/mL
S1676	Amorolfine HCl	9 mg/mL	28 mg/mL	'71 mg/mL
S4075	Zinc Pyrithione	<1 mg/mL	30 mg/mL	'<1 mg/mL
S2536	Miconazole	<1 mg/mL	83 mg/mL	'83 mg/mL
S1910	Tioconazole	<1 mg/mL	78 mg/mL	'78 mg/mL
S4120	Sulconazole Nitrate	<1 mg/mL	92 mg/mL	''<1 mg/mL
S3154	Butenafine HCl	<1 mg/mL	70 mg/mL	'70 mg/mL
S3156	Naftifine HCl	<1 mg/mL	<1 mg/mL	'8 mg/mL
S1833	Butoconazole nitrate	<1 mg/mL	95 mg/mL	''<1 mg/mL
S4806	Potassium 1-Naphthaleneacetate	-1 mg/mL	44 mg/mL	'-1 mg/mL
S9200	Pneumocandin B0	-1 mg/mL	100 mg/mL	-1 mg/mL
S6254	Hydrocinnamic acid	-1 mg/mL	30 mg/mL	'-1 mg/mL
S4581	Triacetin			' mg/mL
S5944	Butenafine	<1 mg/mL	63 mg/mL	'63 mg/mL
S5359	Butoconazole	-1 mg/mL	82 mg/mL	'-1 mg/mL
S8095	Tubercidin	<1 mg/mL	53 mg/mL	'<1 mg/mL
S3966	Nifuratel	<1 mg/mL	57 mg/mL	'<1 mg/mL
S4970	Nerol			' mg/mL
S3829	Isoalantolactone	-1 mg/mL	46 mg/mL	-1 mg/mL
S2058	Tolnaftate	<1 mg/mL	62 mg/mL	'<1 mg/mL
S4584	Butylparaben	38 mg/mL	38 mg/mL	'38 mg/mL
S0770	Camalexin			' mg/mL
S4996	Tavaborole (AN-2690)	<1 mg/mL	30 mg/mL	''30 mg/mL
S5271	Suloctidil	-1 mg/mL	67 mg/mL	'-1 mg/mL
S4755	lanosterol	<1 mg/mL	<1 mg/mL	'6 mg/mL
S3778	Patchouli alcohol	-1 mg/mL	44 mg/mL	-1 mg/mL
S4963	Purpurin	-1 mg/mL	51 mg/mL	-1 mg/mL
S4178	Climbazole	<1 mg/mL	59 mg/mL	'59 mg/mL
S6270	2-Aminoisobutyric acid	10 mg/mL	<1 mg/mL	'-1 mg/mL
S4187	Salicylanilide	<1 mg/mL	43 mg/mL	'18 mg/mL
S3676	Carbendazim	<1 mg/mL	17 mg/mL	'<1 mg/mL
S4258	Luliconazole	<1 mg/mL	71 mg/mL	'5 mg/mL
S9350	Ethyl 4-Methoxycinnamate	-1 mg/mL	41 mg/mL	-1 mg/mL
S9057	Sinigrin	-1 mg/mL	79 mg/mL	-1 mg/mL
S2534	Isoconazole nitrate	<1 mg/mL	41 mg/mL	'4 mg/mL
S5704	Myclobutanil	-1 mg/mL	58 mg/mL	'-1 mg/mL
S3705	Chlorobutanol	<1 mg/mL	35 mg/mL	''35 mg/mL
S9072	Sweroside	-1 mg/mL	71 mg/mL	-1 mg/mL
S2321	Magnolol	<1 mg/mL	53 mg/mL	53 mg/mL
S6408	Hexetidine			' mg/mL
S5033	Terconazole	<1 mg/mL	49 mg/mL	''100 mg/mL
S5025	Efinaconazole	<1 mg/mL	69 mg/mL	'69 mg/mL
S9413	Yangonin	-1 mg/mL	51 mg/mL	-1 mg/mL
S5724	Dichlorophen	-1 mg/mL	54 mg/mL	''-1 mg/mL
S5829	Monomyristin	<1 mg/mL	60 mg/mL	'60 mg/mL
S4601	Clioquinol	<1 mg/mL	61 mg/mL	'1 mg/mL
S6451	Salifungin	<1 mg/mL	65 mg/mL	'5 mg/mL
S3722	Isavuconazole	<1 mg/mL	87 mg/mL	'87 mg/mL
S5541	Dimetridazole	-1 mg/mL	28 mg/mL	'-1 mg/mL
S3979	Zinc Undecylenate	-1 mg/mL	36 mg/mL	'-1 mg/mL
S6467	Fosfluconazole	<1 mg/mL	19 mg/mL	'<1 mg/mL
S9444	Tomatine	-1 mg/mL	100 mg/mL	-1 mg/mL
S4525	Ethylparaben	<1 mg/mL	33 mg/mL	''33 mg/mL
S4878	Neticonazole Hydrochloride	-1 mg/mL	67 mg/mL	'-1 mg/mL
S5845	Chalcone	<1 mg/mL	42 mg/mL	''42 mg/mL
S4793	Cedryl acetate	-1 mg/mL	52 mg/mL	-1 mg/mL
S5512	Juglone	-1 mg/mL	34 mg/mL	-1 mg/mL
S4516	(+)-Camphor	<1 mg/mL	30 mg/mL	'30 mg/mL
S5373	Pseudolaric Acid B	<1 mg/mL	86 mg/mL	86 mg/mL
S4843	Potassium acetate	-1 mg/mL	6 mg/mL	'-1 mg/mL
S4286	Anidulafungin (LY303366)	<1 mg/mL	100 mg/mL	'<1 mg/mL
S3910	4',7-Dimethoxyisoflavone	-1 mg/mL	4 mg/mL	-1 mg/mL
S4287	Micafungin (FK 463) Sodium	100 mg/mL	-1 mg/mL	'''-1 mg/mL
S4559	Cloxiquine	<1 mg/mL	35 mg/mL	''35 mg/mL
S3985	Methyl 4-hydroxybenzoate	-1 mg/mL	30 mg/mL	'-1 mg/mL
S0491	Manogepix (E1210)	<1 mg/mL	72 mg/mL	'20 mg/mL
S3990	Trans-Anethole	-1 mg/mL	29 mg/mL	-1 mg/mL
S1442	Voriconazole (UK-109496)	<1 mg/mL	70 mg/mL	''20 mg/mL
S5174	Kojic acid	-1 mg/mL	28 mg/mL	-1 mg/mL
S5083	Lentinan	-1 mg/mL	100 mg/mL	-1 mg/mL

Fungal製品

All (101) Fungal阻害剤(98)

製品コード	製品説明	文献中Selleckの製品使用例	お客様のフィードバック
S1517	Natamycin Natamycin (Pimaricin), a natural and versatile anti-fungal agent during fermentation by the bacterium Streptomyces natalensis, commonly found in soil; with little to no flavour interference	Expert Opin Drug Deliv, 2020, 17(3):407-421 BMC Microbiol, 2020, 20(1):275
S2476	Itraconazole (R 51211) Itraconazole (R 51211) is a relatively potent inhibitor of CYP3A4 with IC50 of 6.1 nM, used as a triazole antifungal agent. Itraconazole is a potent antagonist of the Hedgehog (Hh) signaling pathway. Itraconazole suppresses the growth of glioblastoma through induction of autophagy.	Nat Biotechnol, 2021, 10.1038/s41587-021-00860-4 Front Microbiol, 2021, 12:649026 Antimicrob Agents Chemother, 2020, 6 pii: AAC	Resistance to itraconazole in MA cells. The parental SUM149-Luc cell line and MA1 cells were treated in parallel with 1 mM itraconazole for 9 days (which killed most of the cells in the parental cell line) and were allowed to recover and grow in a drug-free medium for 5 days before being stained. Since itraconazole was ineffective in killing MA1 cells, the cells grew into a continuous monolayer rather than colonies.
S1331	Fluconazole (UK 49858) Fluconazole (UK 49858) is a fungal lanosterol 14 alpha-demethylase inhibitor, which thereby prevents the formation of ergosterol,used in the treatment and prevention of superficial and systemic fungal infections.	Front Microbiol, 2021, 12:649026 ACS Omega, 2021, 6(12):8477-8487 PLoS Pathog, 2020, 16;16(3):e1008341
S1934	Nystatin (Fungicidin) Nystatin, which belongs to the polyene group of antimycotics, is frequently used as a topical agent in the treatment of oro-pharyngeal candidosis.	J Colloid Interface Sci, 2021, 601:650-660 Biochim Biophys Acta Mol Cell Res, 2020, 1867(5):118676 Neoplasia, 2020, 22(10):470-483
S5080^新	Neticonazole Neticonazole (SS717) is a selecvie inhibitor of exosome biogenesis and secretion. Neticonazole exhibits Neticonazole antifungal and antitumor activity.
S3588^新	Hexylene glycol Hexylene glycol (HG, 2-Methyl-2,4-pentanediol, MPD) is an oxygenated solvent derived from acetone that has been used widely in industrial chemicals and cosmetics. Hexylene glycol exhibits antibacterial and antifungal properties.
S3595^新	D-Gluconic acid D-Gluconic acid is an antifungal agent.
S3532^新	AN-2718 AN-2718 is an inhibitor of fungal growth that blocks protein synthesis via the oxaborole tRNA trapping (OBORT) mechanism.
S0938^新	Sakuranetin Sakuranetin is a rice flavonoid phytoalexin that shows antifungal activity. Sakuranetin has anti-inflammatory and antioxidative activities. Sakuranetin ameliorates LPS-induced acute lung injury.
S0832^新	Dimboa Dimboa (2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one) is an antifungal agent used in crops.
S0971^新	Kakuol Kakuol is a natural compound extracted from the rhizomes of Asarum sieboldii with antifungal activity.
S3373^新	Deoxylapachol Deoxylapachol is a major cytotoxic component of New Zealand brown alga, Landsburgia quercifolia with antifungal and anti-cancer activity.
S3307^新	Galangin 3-methyl ether Galangin 3-methyl ether (3-O-Methylgalangin, 3-Methylgalangin), isolated from Lychnophora markgravii aerial parts, shows strong antibacterial and antifungal effects.
S0917^新	Allosecurinin Allosecurinine (Phyllochrysine) is a Securinega alkaloid isolated from M.indica and M.discoidea with antifungal activity.
S1725	Terbinafine Terbinafine (SF 86-327) is used to treat infections caused by a fungus. It works by killing the fungus or preventing its growth.	J Cell Mol Med, 2020, 25 Arch Dermatol Res, 2020, 312(5):337-352 Eur J Pharm Sci, 2019, 136:104945
S1606	Clotrimazole Clotrimazole (BAY b 5097, FB 5097) alters the permeability of the fungal cell wall by inhibiting the biosynthesis of ergosterol, used in the treatment of fungal infections.	Nat Biotechnol, 2021, 10.1038/s41587-021-00860-4 J Cell Physiol, 2020, 10.1002 J Biol Chem, 2018, 293(1):333-344
S1956	Miconazole Nitrate Miconazole (NSC 169434) Nitrate is an imidazole antifungal agent by inhibiting ergosterol biosynthesis and inducing ROS, used to treat vaginal yeast infections.	Nat Biotechnol, 2021, 10.1038/s41587-021-00860-4 Biomol Ther (Seoul), 2020, 25 Cell Death Dis, 2019, 10(6):413
S1666	Flucytosine Flucytosine (5-Fluorocytosine, 5-FC, 5-Fluorocytosine, NSC 103805, Ro 2-9915) is an antifungal drug with IC50 of 0.93 μM in C. albicans.
S2557	Terbinafine HCl Terbinafine HCl (KWD 201) inhibits ergosterol synthesis by inhibiting squalene epoxidase, used as an antifungal drug.	Hum Mol Genet, 2020, ddaa244 J Cell Mol Med, 2020, 25
S3073	Caspofungin (MK-0991) Acetate Caspofungin Acetate (MK-0991, L-743872) is an lipopeptide antifungal β-1,3-glucan synthase inhibitor.	Pharmaceuticals (Basel), 2021, 14(4)338 Antimicrob Agents Chemother, 2020, 64(2) Biotechnol Adv, 2019, 37(6):107352
S2528	Ciclopirox Ciclopirox is a broad-spectrum antifungal agent working as an iron chelator.	Free Radic Res, 2021, 1-18 bioRxiv, 2019, 10.1101/748129
S3019	Ciclopirox ethanolamine Ciclopirox ethanolamine (Ciclopirox olamine, HOE 296) is a broad-spectrum antifungal agent working as an iron chelator.	ACS Omega, 2021, 6(12):8477-8487 bioRxiv, 2019, 10.1101/748129
S2535	Econazole nitrate Econazole Nitrate (NSC 243115) is a Ca2+ channel blocker, used as an antifungal medicine that fights infections caused by fungus.	Biomol Ther (Seoul), 2020, 25
S1854	Bifonazole Bifonazole (Bay h 4502) is a substituted imidazole antifungal agent.	Nature, 2018, 560(7718):372-376	Percentage of MBP+ oligodendrocytes generated from OPCs following treatment with azoles (c). n ≥ 4 wells per condition.
S3079	Atovaquone Atovaquone (Atavaquone) is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.	Sci Rep, 2019, 9(1):536 Sci Transl Med, 2015, 7(290):290ra89
S1997	Liranaftate Liranaftate is a squalene epoxidase inhibitor with anti-fungicidal activities.
S3161	Sertaconazole nitrate Sertaconazole nitrate (FI-7045) is a topical broad-spectrum antifungal that is developed to provide an additional agent for the treatment of superficial cutaneous and mucosal infections.
S2031	Fenticonazole Nitrate Fenticonazole Nitrate is an azole antifungal agent.
S1676	Amorolfine HCl Amorolfine HCl is an antifungal reagent.	Nat Commun, 2021, 12(1):652 Cell Chem Biol, 2019, 26(4):593-599 Nature, 2018, 560(7718):372-376	b, GC–MS-based quantification of three metabolite levels in human glioma cells (GBM528) treated for 24 h with the indicated small molecules at the following concentrations: tamoxifen, 100 nM; clemastine, 2 μM; ifenprodil, 2 μM; ketoconazole, 2.5 μM; amorolfine, 100 nM. Left, lanosterol; centre, zymostenol; right, 14-dehydrozymostenol. n = 2 wells per condition.
S4075	Zinc Pyrithione Zinc pyrithione (OM-1563) is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.	Cell Chem Biol, 2021, S2451-9456(21)00213-0 Biol Reprod, 2019, 100(2):468-478 Cell Syst, 2017, 4(6-:600-610
S2536	Miconazole Miconazole (Monistat) is an imidazole antifungal agent.	Drug Test Anal, 2020, 10.1002/dta.2917 Biomol Ther (Seoul), 2020, 25
S1910	Tioconazole Tioconazole (UK-20349) is an antifungal medication with an average IC50 of 1.7 μM.	Chem Biol Drug Des, 2016, 10.1111/cbdd.12872
S4120	Sulconazole Nitrate Sulconazole Nitrate is an imidazole derivative with broad-spectrum antifungal activity.
S3154	Butenafine HCl Butenafine HCl (KP-363) is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase.
S3156	Naftifine HCl Naftifine is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis, probably involves selectively blocking sterol biosynthesis via inhibition of the squalene 2,3-epoxidase enzyme.
S1833	Butoconazole nitrate Butoconazole nitrate (RS-35887) is an anti-fungal agent that inhibits PHA-stimulated release of cytokines-- IL-2, TNFα, IFN and GM-CSF from human peripheral blood lymphocytes (IC50 of 7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL and 7.6 μg/mL, respectively).
S4806	Potassium 1-Naphthaleneacetate Potassium 1-Naphthaleneacetate (KANU, α-Naphthaleneacetic Acid Potassium Salt) is being studied as a synthetic growth factor that affects conidial germination, sporulation, mycelial growth, cell surface morphology, and the viability of certain fungal plant pathogens.
S9200	Pneumocandin B0 Pneumocandin B0 (L-688786) is a natural product and a key intermediate in the synthesis of the antifungal agent.
S6254	Hydrocinnamic acid Hydrocinnamic acid (3-phenylpropionic acid, Benzylacetic acid) is a substrate of the enzyme oxidoreductases in the pathway phenylalanine metabolism (KEGG). It is an antifungal agent and a metabolite.
S4581	Triacetin Triacetin (Glycerol triacetate, Glyceryl triacetate, Glycerin triacetate, 1,2,3-Triacetoxypropane) is a triglyceride that is used as an antifungal agent.
S5553	Kasugamycin hydrochloride Kasugamycin is an aminoglycosidic antibiotic isolated from Streptomyces kasugaensis, showing broad-spectrum anti-fungal activity against yeast and various fungus species.
S5944	Butenafine Butenafine is a synthetic benzylamine antifungal agent.
S5359	Butoconazole Butoconazole is an imidazole antifungal used in gynecology.	Nature, 2018, 560(7718):372-376	Percentage of MBP+ oligodendrocytes generated from OPCs following treatment with azoles (c). n ≥ 4 wells per condition.
S8095	Tubercidin Tubercidin (7-deaza-adenosine), an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhibits antifungal and antiviral activities.	Mol Cell, 2020, 80(6):1104-1122.e9
S3966	Nifuratel Nifuratel is a nitrofuran derivative with local antiprotozoal and antifungal activity and a broad spectrum of antibacterial action.
S4970	Nerol Nerol (Cis-Geraniol, Neryl alcohol) is a monoterpene found in many essential oils such as lemongrass and hops.
S3829	Isoalantolactone Isoalantolactone, one of the major sesquiterpene lactone compounds, is isolated from the roots of Anula helenium and possesses multiple biological activities including antifungal, anthelmintic, antimicrobial, anti-inflammatory, antitrypanosomal activities and antiproliferative effects on several cancer cell lines, such as colon, melanoma, ovary, prostate, lung, and leukemia.
S2058	Tolnaftate Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent.	Cancer Cell Int, 2020, 19;20:58 Hum Cell, 2020, 10.1007/s13577-020-00420-z Hum Cell, 2020, 10.1007/s13577-020-00425-8
S4584	Butylparaben Butylparaben (Butyl parahydroxybenzoate, Butyl 4-hydroxybenzoate) is a chemical compound commonly used as an antifungal preservative in cosmetic products.	Environ Toxicol, 2018, 33(4):436-445
S0770	Camalexin Camalexin, a phytoalexin isolated from Camelina sativa and Arabidopsis (Cruciferae), can induce reactive oxygen species (ROS) production. Camalexin has antibacterial, antifungal, antiproliferative and anticancer activities.
S6118	Terpinen-4-ol Terpinen-4-ol, a naturally occurring monoterpene, is the main bioactive component of tea-tree oil and has been shown to have many biological activities such as antifungal properties.
S4996	Tavaborole (AN-2690) Tavaborole (AN-2690) is a boron-containing small molecule with broad spectrum antifungal activity.
S5271	Suloctidil Suloctidil, a sulfur-containing aminoalcohol showing to inhibit human platelet aggregation, is a peripheral vasodilator and a potential antifungal agent.
S4755	lanosterol Lanosterol is a tetracyclic triterpenoid and is the compound from which all animal and fungal steroids are derived. By contrast plant steroids are produced via cycloartenol.
S3778	Patchouli alcohol Patchouli alcohol (Patchoulol, Patchouli camphor), an ingredient in pogostemonis herba, has various pharmacological activities and acts as an inhibitor of asexual fungal propagation, inflammation, the influenza virus, and tumorigenesis.
S4963	Purpurin Purpurin (1,2,4-Trihydroxyanthraquinone, Hydroxylizaric acid, Verantin) is one of the natural colorants extracted from madder roots and other Rubiaceae family plants. It exhibits anti-angiogenic, antifungal, antibiotic, and antioxidative activities. Purpurin strongly inhibits the activities of CYP1A1, CYP1A2 and CYP1B1.
S4178	Climbazole Climbazole is a broad-spectrum imidazole antifungal agent that can provide anti-dandruff benefits.
S6270	2-Aminoisobutyric acid 2-Aminoisobutyric acid (NSC-16590, 2-Methylalanine, H-Aib-OH) is a rare, non-protein amino acid and end-product of pyrimidine metabolism, excreted in urine and found in some antibiotics of fungal origin.
S4187	Salicylanilide Salicylanilides (WR10019) are a group of compounds with a wide range of biological activities including antiviral potency, antibacterial (including antimycobacterial) and antifungal activities.	Hum Mol Genet, 2020, ddaa244
S3676	Carbendazim Carbendazim (Mercarzole, Carbendazole) is a broad-spectrum systemic antimycotic and can be used to control a broad range of diseases on field crops, fruits, and vegetables, including sclerotinia rot of canola, wheat head blight, peanut leaf spot, and SB on rice. Its mode of action is to inhibit the formation of mitotic microtubules in of fungi.
S4258	Luliconazole Luliconazole is a broad-spectrum antifungal drug.
S9350	Ethyl 4-Methoxycinnamate Ethyl 4-Methoxycinnamate (Ethyl p-methoxycinnamate, 4-Methoxycinnamic Acid Ethyl Ester), a natural product found in K. galanga and C. zedoaria extracts, has anti-inflammatory, antiangiogenic, antifungal, larvicidal, and analgesic activities.
S9057	Sinigrin Sinigrin (Allylglucosinolate, 2-Propenylglucosinolate) is a glucosinolate found in some plants of the Brassicaceae family and exerts various activities including anticancer, anti-inflammatory, antibacterial, antifungal, antioxidant, and wound healing effects.	J Invest Dermatol, 2018, 138(12):2644-2652
S2534	Isoconazole nitrate Isoconazole nitrate (Travogen) is an azole antifungal reagent.
S5704	Myclobutanil Myclobutanil is a widely used triazole fungicide and also a steroid demethylation inhibitor.
S3705	Chlorobutanol Chlorobutanol (Chlorbutol, Chloreton, Chloretone, Chlortran\|, trichloro-2-methyl-2-propanol) is a preservative, sedative, hypnotic and weak local anesthetic with antibacterial and antifungal properties.
S3860	Allicin Allicin (Diallyl Thiosulfinate), the main biologically active component of the freshly crushed garlic extracts, possesses various biological activities including antibacterial, antifungal and antiparasitic effects.
S9072	Sweroside Sweroside, a bioactive herbal ingredient isolated from Fructus Corni, exhibits diverse biological activities, such as anti-fungal, anti-diabetic, anti-inflammatory, and anti-tumor effects.
S2321	Magnolol Magnolol (NSC 293099) is a bioactive lignin found in the bark of the Houpu magnolia (Magnolia officinalis) which shows antifungal properties. It can block TNF-α-induced NF-KB activation.	Neoplasia, 2020, 22(11):576-589 J Chromatogr A, 2020, 1625:461230 Micromachines, 2018, 9(6)	Magnolol reduces RNV areas and avascular areas in OIR mice. Mice retinas from OIR group (a, b) and OIR + Magnolol (25 mg/kg) group (c, d) were harvested at P17 and subjected to wholemount immunostaining with IB4 (red), showing neovascular areas (green) and avascular areas (yellow).
S6408	Hexetidine Hexetidine is an anti-bacterial and anti-fungal agent with local anesthetic, astringent, deodorant and antiplaque activity.
S5033	Terconazole Terconazole (Terazol 3, Terazol 7, Triaconazole, Gyno-Terazol) is a new, broad-spectrum, triazole antifungal agent which is primarily used to treat vaginal fungal infections.	bioRxiv, 2020, 2020/9/20.4.7.30734
S5025	Efinaconazole Efinaconazole (KP-103) is an inhibitor of 14 alpha-demethylase which is involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes.
S9413	Yangonin Yangonin (Y100550) is a dienolide kavalactone originally found in Piper methysticum (kava plant) and exhibits neuroprotective, neuromodulatory, and antifungal activities. It activates cannabinoid (CB1) receptors and potentiates the effects of GABA-A receptors.
S5724	Dichlorophen Dichlorophen (Dichlorophene, Bis(5-chloro-2-hydroxyphenyl)methane) is an anticestodal agent, fungicide, germicide, and antimicrobial agent.
S5829	Monomyristin Monomyristin (Glyceryl myristate, 2,3-Dihydroxypropyl tetradecanoate), a monoacylglyceride, shows high antibacterial and antifungal activities.
S4601	Clioquinol Clioquinol (Iodochlorhydroxyquin, Chinoform) is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities.	FASEB J, 2019, 10.1096/fj.201802603RR
S6451	Salifungin Salifungin (Multifungin, Bromosalicylchloranilide) is an antifungal and may cause allergic contact dermatitis in some individuals.
S3722	Isavuconazole Isavuconazole (BAL-4815, RO-0094815) is a new extended-spectrum triazole with activity against yeasts, molds, and dimorphic fungi that inhibits cytochrome P450 (CYP)-dependent 14α-lanosterol demethylation, which is essential for fungal cell membrane ergosterol synthesis.
S5541	Dimetridazole Dimetridazole is an anti-fungal and anti-protozoal used for the control of infection in pigs, poultry, turkeys, game birds, pigeons and other caged birds.
S3979	Zinc Undecylenate Zinc Undecylenate (Zinc diundec-10-enoate, Zinc 10-undecenoate) is a natural or synthetic fungistatic fatty acid, antifungal Zinc Undecylenate is used topically in creams against fungal infections, eczemas, ringworm, and other cutaneous conditions.
S5086	p-Anisaldehyde p-Anisaldehyde (4-Methoxybenzaldehyde, Anisaldehyde, Anisic aldehyde, P-Methoxybenzaldehyde, 4-Anisaldehyde), an extract from Pimpinella anisum seeds, exhibits antifungal activity against a number of yeast and mold strains in laboratory media, fruit purees and fruit juices.
S6467	Fosfluconazole Fosfluconazole is a water-soluble phosphate prodrug of fluconazole, which is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.
S9444	Tomatine Tomatine (Lycopersicin) is a natural glycoalkaloid with fungicidal, antimicrobial, and insecticidal properties.
S4525	Ethylparaben Ethylparaben (Ethyl parahydroxybenzoate, Ethyl 4-hydroxybenzoate) is the ethyl ester of p-hydroxybenzoic acid, used as an antifungal preservative and food additive. It is a standardized chemical allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity.
S4878	Neticonazole Hydrochloride Neticonazole is an imidazole antifungal for the treatment of fungal skin infections.
S5845	Chalcone Chalcone (benzylideneacetophenone, phenyl styryl ketone, benzalacetophenone, β-phenylacrylophenone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones with antibacterial, antifungal, antitumor and anti-inflammatory properties.
S4793	Cedryl acetate Cedryl Acetate (Cedrol acetate, Cedranyl acetate), an acetylated from cedarwood oil, has been applied to chemistry for its properties as a chiral and cell signaling reagent with antifungal and immunotoxicity functions. Cedryl acetate exhibits α-glucosidase inhibitory activity.
S5512	Juglone Juglone (Regianin, 5-Hydroxy-1,4-naphthoquinone), a natural naphthoquinone found in the black walnut and other plants, has moderate antifungal activity and growth-stimulating effects to many types of plants. It sometimes can be used as an herbicide, as a dye for cloth and inks, and as a coloring agent for foods and cosmetics.	Nat Commun, 2019, 10(1):4013
S4516	(+)-Camphor Camphor is a waxy, flammable, white or transparent solid with a strong aroma, often used to relieve pain, reduce itching and treat fungal infections. It can activate TRPV1 and TRPV3.
S5373	Pseudolaric Acid B Pseudolaric Acid B, a natural diterpenoid compound isolated from the root and trunk bark of Pseudolaric kaempferi Gordon, has anti-fungal and anti-fertility properties.	Eur J Pharmacol, 2020, 876:173064
S4843	Potassium acetate Potassium acetate (Diuretic salt, Potassium ethanoate) is the potassium salt of acetic acid, which is a synthetic carboxylic acid with antibacterial and antifungal properties.
S4286	Anidulafungin (LY303366) Anidulafungin (LY303366), an echinocandin derivative, inhibits glucan synthase activity, used as an antifungal drug.	Pharmaceuticals (Basel), 2021, 14(4)338 Emerg Microbes Infect, 2020, 1-53 Antimicrob Agents Chemother, 2020, 64(2)	Effect of Anidulafungin on hemolysis. Arithmetic means ± SEM (n = 8) of the percentage of hemolytic erythrocytes following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Anidulafungin (1.5-6 μg/ml). ***(p<0.001) indicates significant difference from the absence of Anidulafungin (ANOVA).
S3910	4',7-Dimethoxyisoflavone 4',7-Dimethoxyisoflavone, isolated from the leaves of Albizzia lebbeck, shows antifungal activity in vitro.
S4287	Micafungin (FK 463) Sodium Micafungin Sodium (FK463, Mycamine) is an inhibitor of 1, 3-beta-D-glucan synthesis, used as an antifungal drug.	Bioorg Med Chem, 2021, 44:116293 Pharmaceuticals (Basel), 2021, 14(4)338 Antimicrob Agents Chemother, 2020, 64(2)	Effect of Micafungin on erythrocyte forward scatter. A. Original histogram of forward scatter of erythrocytes following exposure for 48 hours to Ringer solution without (grey area) and with (black line) presense of 25 µg/ml Micafungin. B. Arithmetic means ± SEM (n = 14) of the erythrocyte forward scatter (FSC) following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Micafungin (10-25 µg/ml). C. Arithmetic means ± SEM (n = 14) of the percentage of erythrocytes with forward scatter(FSC) <200 following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Micafungin (10-25 µg/ml). D. Arithmetic means ± SEM (n = 14) of the percentage of erythrocytes with forward scatter (FSC) >800 following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Micafungin (10-25 µg/ml). ***(p<0.001) indicates significant difference from the absence of Micafungin (ANOVA).
S4559	Cloxiquine Cloxiquine (5-Chloro-8-quinolinol, Dermofungin) is an antibacterial, antifungal, antiaging and antituberculosis drug.
S3985	Methyl 4-hydroxybenzoate Methyl 4-hydroxybenzoate (Methylparaben, Methyl p-hydroxybenzoate, Nipagin) is an anti-fungal agent often used in a variety of cosmetics, personal-care products and food preservatives.
S0491	Manogepix (E1210) Manogepix (E1210, MGX, APX001A) is a broad-spectrum and orally active antifungal agent that inhibits Gwt1/Gwt1p (GPI-anchored wall transfer protein 1), a protein that plays an important role in fungal cell wall integrity.
S3990	Trans-Anethole Trans-anethole (4-Propenylanisole) is a phenylpropene derivative found in many essential oils, including anise oil. It has neuromodulatory, anxiolytic, antioxidative, antifungal, anti-inflammatory, and immunomodulatory activities.
S1442	Voriconazole (UK-109496) Voriconazole (UK-109496) is a new triazole derivative similar to fluconazole and itraconazole that acts by inhibiting fungal cytochrome P-450-dependent, 14-alpha-sterol demethylase-mediated synthesis of ergosterol.	Front Microbiol, 2021, 12:649026 Antimicrob Agents Chemother, 2020, 6 pii: AAC Front Microbiol, 2020, 11:579362	Voriconazole increases the osteogenic activity of human osteoblasts in vitro. Osteoblasts were exposed to voriconazole (VCZ) or fluconazole (FCZ) at 15 or 200 μg/ml in osteoinductive medium (OS+) for up to 7 days. As a positive control, cells were also exposed to sodium fluoride (NaF) at 10 μM in nonosteoinductive medium (OS−). Osteoblastic differentiation was evaluated by measuring alkaline phosphatase (ALP) activity (A) and staining for calcium deposition with alazarin red S stain (B and C); calcium deposition was quantified by measuring the absorbance (A415) of extracted alazarin red S (B) and was assessed by the light microscopic appearance (white arrows) of stained osteoblast cultures (C). Values represent the means ± SD. *, P < 0.05, compared to osteoblasts grown under osteogenic conditions without treatment.
S5174	Kojic acid Kojic acid is a fungal metabolite that inhibits tyrosinase with an IC50 value of 30.6 µM for mushroom tyrosinase. It is a synthetic intermediate used for production of food additives.	Int J Mol Sci, 2017, 18(9)
S5083	Lentinan Lentinan (A823605, Bromoduline), isolated and purified from a hot water extract of Lentinula edodes fruit bodies, is a fungal polysaccharide immunomodulator with anti-tumor effects.

製品コード	製品説明	文献中Selleckの製品使用例	お客様のフィードバック
S1517	Natamycin Natamycin (Pimaricin), a natural and versatile anti-fungal agent during fermentation by the bacterium Streptomyces natalensis, commonly found in soil; with little to no flavour interference	Expert Opin Drug Deliv, 2020, 17(3):407-421 BMC Microbiol, 2020, 20(1):275
S2476	Itraconazole (R 51211) Itraconazole (R 51211) is a relatively potent inhibitor of CYP3A4 with IC50 of 6.1 nM, used as a triazole antifungal agent. Itraconazole is a potent antagonist of the Hedgehog (Hh) signaling pathway. Itraconazole suppresses the growth of glioblastoma through induction of autophagy.	Nat Biotechnol, 2021, 10.1038/s41587-021-00860-4 Front Microbiol, 2021, 12:649026 Antimicrob Agents Chemother, 2020, 6 pii: AAC	Resistance to itraconazole in MA cells. The parental SUM149-Luc cell line and MA1 cells were treated in parallel with 1 mM itraconazole for 9 days (which killed most of the cells in the parental cell line) and were allowed to recover and grow in a drug-free medium for 5 days before being stained. Since itraconazole was ineffective in killing MA1 cells, the cells grew into a continuous monolayer rather than colonies.
S1331	Fluconazole (UK 49858) Fluconazole (UK 49858) is a fungal lanosterol 14 alpha-demethylase inhibitor, which thereby prevents the formation of ergosterol,used in the treatment and prevention of superficial and systemic fungal infections.	Front Microbiol, 2021, 12:649026 ACS Omega, 2021, 6(12):8477-8487 PLoS Pathog, 2020, 16;16(3):e1008341
S1934	Nystatin (Fungicidin) Nystatin, which belongs to the polyene group of antimycotics, is frequently used as a topical agent in the treatment of oro-pharyngeal candidosis.	J Colloid Interface Sci, 2021, 601:650-660 Biochim Biophys Acta Mol Cell Res, 2020, 1867(5):118676 Neoplasia, 2020, 22(10):470-483
S5080^新	Neticonazole Neticonazole (SS717) is a selecvie inhibitor of exosome biogenesis and secretion. Neticonazole exhibits Neticonazole antifungal and antitumor activity.
S3588^新	Hexylene glycol Hexylene glycol (HG, 2-Methyl-2,4-pentanediol, MPD) is an oxygenated solvent derived from acetone that has been used widely in industrial chemicals and cosmetics. Hexylene glycol exhibits antibacterial and antifungal properties.
S3595^新	D-Gluconic acid D-Gluconic acid is an antifungal agent.
S3532^新	AN-2718 AN-2718 is an inhibitor of fungal growth that blocks protein synthesis via the oxaborole tRNA trapping (OBORT) mechanism.
S0938^新	Sakuranetin Sakuranetin is a rice flavonoid phytoalexin that shows antifungal activity. Sakuranetin has anti-inflammatory and antioxidative activities. Sakuranetin ameliorates LPS-induced acute lung injury.
S0832^新	Dimboa Dimboa (2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one) is an antifungal agent used in crops.
S0971^新	Kakuol Kakuol is a natural compound extracted from the rhizomes of Asarum sieboldii with antifungal activity.
S3373^新	Deoxylapachol Deoxylapachol is a major cytotoxic component of New Zealand brown alga, Landsburgia quercifolia with antifungal and anti-cancer activity.
S3307^新	Galangin 3-methyl ether Galangin 3-methyl ether (3-O-Methylgalangin, 3-Methylgalangin), isolated from Lychnophora markgravii aerial parts, shows strong antibacterial and antifungal effects.
S0917^新	Allosecurinin Allosecurinine (Phyllochrysine) is a Securinega alkaloid isolated from M.indica and M.discoidea with antifungal activity.
S1725	Terbinafine Terbinafine (SF 86-327) is used to treat infections caused by a fungus. It works by killing the fungus or preventing its growth.	J Cell Mol Med, 2020, 25 Arch Dermatol Res, 2020, 312(5):337-352 Eur J Pharm Sci, 2019, 136:104945
S1606	Clotrimazole Clotrimazole (BAY b 5097, FB 5097) alters the permeability of the fungal cell wall by inhibiting the biosynthesis of ergosterol, used in the treatment of fungal infections.	Nat Biotechnol, 2021, 10.1038/s41587-021-00860-4 J Cell Physiol, 2020, 10.1002 J Biol Chem, 2018, 293(1):333-344
S1956	Miconazole Nitrate Miconazole (NSC 169434) Nitrate is an imidazole antifungal agent by inhibiting ergosterol biosynthesis and inducing ROS, used to treat vaginal yeast infections.	Nat Biotechnol, 2021, 10.1038/s41587-021-00860-4 Biomol Ther (Seoul), 2020, 25 Cell Death Dis, 2019, 10(6):413
S1666	Flucytosine Flucytosine (5-Fluorocytosine, 5-FC, 5-Fluorocytosine, NSC 103805, Ro 2-9915) is an antifungal drug with IC50 of 0.93 μM in C. albicans.
S2557	Terbinafine HCl Terbinafine HCl (KWD 201) inhibits ergosterol synthesis by inhibiting squalene epoxidase, used as an antifungal drug.	Hum Mol Genet, 2020, ddaa244 J Cell Mol Med, 2020, 25
S3073	Caspofungin (MK-0991) Acetate Caspofungin Acetate (MK-0991, L-743872) is an lipopeptide antifungal β-1,3-glucan synthase inhibitor.	Pharmaceuticals (Basel), 2021, 14(4)338 Antimicrob Agents Chemother, 2020, 64(2) Biotechnol Adv, 2019, 37(6):107352
S2528	Ciclopirox Ciclopirox is a broad-spectrum antifungal agent working as an iron chelator.	Free Radic Res, 2021, 1-18 bioRxiv, 2019, 10.1101/748129
S3019	Ciclopirox ethanolamine Ciclopirox ethanolamine (Ciclopirox olamine, HOE 296) is a broad-spectrum antifungal agent working as an iron chelator.	ACS Omega, 2021, 6(12):8477-8487 bioRxiv, 2019, 10.1101/748129
S2535	Econazole nitrate Econazole Nitrate (NSC 243115) is a Ca2+ channel blocker, used as an antifungal medicine that fights infections caused by fungus.	Biomol Ther (Seoul), 2020, 25
S1854	Bifonazole Bifonazole (Bay h 4502) is a substituted imidazole antifungal agent.	Nature, 2018, 560(7718):372-376	Percentage of MBP+ oligodendrocytes generated from OPCs following treatment with azoles (c). n ≥ 4 wells per condition.
S3079	Atovaquone Atovaquone (Atavaquone) is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.	Sci Rep, 2019, 9(1):536 Sci Transl Med, 2015, 7(290):290ra89
S1997	Liranaftate Liranaftate is a squalene epoxidase inhibitor with anti-fungicidal activities.
S3161	Sertaconazole nitrate Sertaconazole nitrate (FI-7045) is a topical broad-spectrum antifungal that is developed to provide an additional agent for the treatment of superficial cutaneous and mucosal infections.
S2031	Fenticonazole Nitrate Fenticonazole Nitrate is an azole antifungal agent.
S1676	Amorolfine HCl Amorolfine HCl is an antifungal reagent.	Nat Commun, 2021, 12(1):652 Cell Chem Biol, 2019, 26(4):593-599 Nature, 2018, 560(7718):372-376	b, GC–MS-based quantification of three metabolite levels in human glioma cells (GBM528) treated for 24 h with the indicated small molecules at the following concentrations: tamoxifen, 100 nM; clemastine, 2 μM; ifenprodil, 2 μM; ketoconazole, 2.5 μM; amorolfine, 100 nM. Left, lanosterol; centre, zymostenol; right, 14-dehydrozymostenol. n = 2 wells per condition.
S4075	Zinc Pyrithione Zinc pyrithione (OM-1563) is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.	Cell Chem Biol, 2021, S2451-9456(21)00213-0 Biol Reprod, 2019, 100(2):468-478 Cell Syst, 2017, 4(6-:600-610
S2536	Miconazole Miconazole (Monistat) is an imidazole antifungal agent.	Drug Test Anal, 2020, 10.1002/dta.2917 Biomol Ther (Seoul), 2020, 25
S1910	Tioconazole Tioconazole (UK-20349) is an antifungal medication with an average IC50 of 1.7 μM.	Chem Biol Drug Des, 2016, 10.1111/cbdd.12872
S4120	Sulconazole Nitrate Sulconazole Nitrate is an imidazole derivative with broad-spectrum antifungal activity.
S3154	Butenafine HCl Butenafine HCl (KP-363) is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase.
S3156	Naftifine HCl Naftifine is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis, probably involves selectively blocking sterol biosynthesis via inhibition of the squalene 2,3-epoxidase enzyme.
S1833	Butoconazole nitrate Butoconazole nitrate (RS-35887) is an anti-fungal agent that inhibits PHA-stimulated release of cytokines-- IL-2, TNFα, IFN and GM-CSF from human peripheral blood lymphocytes (IC50 of 7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL and 7.6 μg/mL, respectively).
S4806	Potassium 1-Naphthaleneacetate Potassium 1-Naphthaleneacetate (KANU, α-Naphthaleneacetic Acid Potassium Salt) is being studied as a synthetic growth factor that affects conidial germination, sporulation, mycelial growth, cell surface morphology, and the viability of certain fungal plant pathogens.
S9200	Pneumocandin B0 Pneumocandin B0 (L-688786) is a natural product and a key intermediate in the synthesis of the antifungal agent.
S6254	Hydrocinnamic acid Hydrocinnamic acid (3-phenylpropionic acid, Benzylacetic acid) is a substrate of the enzyme oxidoreductases in the pathway phenylalanine metabolism (KEGG). It is an antifungal agent and a metabolite.
S4581	Triacetin Triacetin (Glycerol triacetate, Glyceryl triacetate, Glycerin triacetate, 1,2,3-Triacetoxypropane) is a triglyceride that is used as an antifungal agent.
S5553	Kasugamycin hydrochloride Kasugamycin is an aminoglycosidic antibiotic isolated from Streptomyces kasugaensis, showing broad-spectrum anti-fungal activity against yeast and various fungus species.
S5944	Butenafine Butenafine is a synthetic benzylamine antifungal agent.
S5359	Butoconazole Butoconazole is an imidazole antifungal used in gynecology.	Nature, 2018, 560(7718):372-376	Percentage of MBP+ oligodendrocytes generated from OPCs following treatment with azoles (c). n ≥ 4 wells per condition.
S8095	Tubercidin Tubercidin (7-deaza-adenosine), an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhibits antifungal and antiviral activities.	Mol Cell, 2020, 80(6):1104-1122.e9
S3966	Nifuratel Nifuratel is a nitrofuran derivative with local antiprotozoal and antifungal activity and a broad spectrum of antibacterial action.
S4970	Nerol Nerol (Cis-Geraniol, Neryl alcohol) is a monoterpene found in many essential oils such as lemongrass and hops.
S3829	Isoalantolactone Isoalantolactone, one of the major sesquiterpene lactone compounds, is isolated from the roots of Anula helenium and possesses multiple biological activities including antifungal, anthelmintic, antimicrobial, anti-inflammatory, antitrypanosomal activities and antiproliferative effects on several cancer cell lines, such as colon, melanoma, ovary, prostate, lung, and leukemia.
S2058	Tolnaftate Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent.	Cancer Cell Int, 2020, 19;20:58 Hum Cell, 2020, 10.1007/s13577-020-00420-z Hum Cell, 2020, 10.1007/s13577-020-00425-8
S4584	Butylparaben Butylparaben (Butyl parahydroxybenzoate, Butyl 4-hydroxybenzoate) is a chemical compound commonly used as an antifungal preservative in cosmetic products.	Environ Toxicol, 2018, 33(4):436-445
S0770	Camalexin Camalexin, a phytoalexin isolated from Camelina sativa and Arabidopsis (Cruciferae), can induce reactive oxygen species (ROS) production. Camalexin has antibacterial, antifungal, antiproliferative and anticancer activities.
S6118	Terpinen-4-ol Terpinen-4-ol, a naturally occurring monoterpene, is the main bioactive component of tea-tree oil and has been shown to have many biological activities such as antifungal properties.
S4996	Tavaborole (AN-2690) Tavaborole (AN-2690) is a boron-containing small molecule with broad spectrum antifungal activity.
S5271	Suloctidil Suloctidil, a sulfur-containing aminoalcohol showing to inhibit human platelet aggregation, is a peripheral vasodilator and a potential antifungal agent.
S4755	lanosterol Lanosterol is a tetracyclic triterpenoid and is the compound from which all animal and fungal steroids are derived. By contrast plant steroids are produced via cycloartenol.
S3778	Patchouli alcohol Patchouli alcohol (Patchoulol, Patchouli camphor), an ingredient in pogostemonis herba, has various pharmacological activities and acts as an inhibitor of asexual fungal propagation, inflammation, the influenza virus, and tumorigenesis.
S4963	Purpurin Purpurin (1,2,4-Trihydroxyanthraquinone, Hydroxylizaric acid, Verantin) is one of the natural colorants extracted from madder roots and other Rubiaceae family plants. It exhibits anti-angiogenic, antifungal, antibiotic, and antioxidative activities. Purpurin strongly inhibits the activities of CYP1A1, CYP1A2 and CYP1B1.
S4178	Climbazole Climbazole is a broad-spectrum imidazole antifungal agent that can provide anti-dandruff benefits.
S6270	2-Aminoisobutyric acid 2-Aminoisobutyric acid (NSC-16590, 2-Methylalanine, H-Aib-OH) is a rare, non-protein amino acid and end-product of pyrimidine metabolism, excreted in urine and found in some antibiotics of fungal origin.
S4187	Salicylanilide Salicylanilides (WR10019) are a group of compounds with a wide range of biological activities including antiviral potency, antibacterial (including antimycobacterial) and antifungal activities.	Hum Mol Genet, 2020, ddaa244
S3676	Carbendazim Carbendazim (Mercarzole, Carbendazole) is a broad-spectrum systemic antimycotic and can be used to control a broad range of diseases on field crops, fruits, and vegetables, including sclerotinia rot of canola, wheat head blight, peanut leaf spot, and SB on rice. Its mode of action is to inhibit the formation of mitotic microtubules in of fungi.
S4258	Luliconazole Luliconazole is a broad-spectrum antifungal drug.
S9350	Ethyl 4-Methoxycinnamate Ethyl 4-Methoxycinnamate (Ethyl p-methoxycinnamate, 4-Methoxycinnamic Acid Ethyl Ester), a natural product found in K. galanga and C. zedoaria extracts, has anti-inflammatory, antiangiogenic, antifungal, larvicidal, and analgesic activities.
S9057	Sinigrin Sinigrin (Allylglucosinolate, 2-Propenylglucosinolate) is a glucosinolate found in some plants of the Brassicaceae family and exerts various activities including anticancer, anti-inflammatory, antibacterial, antifungal, antioxidant, and wound healing effects.	J Invest Dermatol, 2018, 138(12):2644-2652
S2534	Isoconazole nitrate Isoconazole nitrate (Travogen) is an azole antifungal reagent.
S5704	Myclobutanil Myclobutanil is a widely used triazole fungicide and also a steroid demethylation inhibitor.
S3705	Chlorobutanol Chlorobutanol (Chlorbutol, Chloreton, Chloretone, Chlortran\|, trichloro-2-methyl-2-propanol) is a preservative, sedative, hypnotic and weak local anesthetic with antibacterial and antifungal properties.
S3860	Allicin Allicin (Diallyl Thiosulfinate), the main biologically active component of the freshly crushed garlic extracts, possesses various biological activities including antibacterial, antifungal and antiparasitic effects.
S9072	Sweroside Sweroside, a bioactive herbal ingredient isolated from Fructus Corni, exhibits diverse biological activities, such as anti-fungal, anti-diabetic, anti-inflammatory, and anti-tumor effects.
S2321	Magnolol Magnolol (NSC 293099) is a bioactive lignin found in the bark of the Houpu magnolia (Magnolia officinalis) which shows antifungal properties. It can block TNF-α-induced NF-KB activation.	Neoplasia, 2020, 22(11):576-589 J Chromatogr A, 2020, 1625:461230 Micromachines, 2018, 9(6)	Magnolol reduces RNV areas and avascular areas in OIR mice. Mice retinas from OIR group (a, b) and OIR + Magnolol (25 mg/kg) group (c, d) were harvested at P17 and subjected to wholemount immunostaining with IB4 (red), showing neovascular areas (green) and avascular areas (yellow).
S6408	Hexetidine Hexetidine is an anti-bacterial and anti-fungal agent with local anesthetic, astringent, deodorant and antiplaque activity.
S5033	Terconazole Terconazole (Terazol 3, Terazol 7, Triaconazole, Gyno-Terazol) is a new, broad-spectrum, triazole antifungal agent which is primarily used to treat vaginal fungal infections.	bioRxiv, 2020, 2020/9/20.4.7.30734
S5025	Efinaconazole Efinaconazole (KP-103) is an inhibitor of 14 alpha-demethylase which is involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes.
S9413	Yangonin Yangonin (Y100550) is a dienolide kavalactone originally found in Piper methysticum (kava plant) and exhibits neuroprotective, neuromodulatory, and antifungal activities. It activates cannabinoid (CB1) receptors and potentiates the effects of GABA-A receptors.
S5724	Dichlorophen Dichlorophen (Dichlorophene, Bis(5-chloro-2-hydroxyphenyl)methane) is an anticestodal agent, fungicide, germicide, and antimicrobial agent.
S5829	Monomyristin Monomyristin (Glyceryl myristate, 2,3-Dihydroxypropyl tetradecanoate), a monoacylglyceride, shows high antibacterial and antifungal activities.
S4601	Clioquinol Clioquinol (Iodochlorhydroxyquin, Chinoform) is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities.	FASEB J, 2019, 10.1096/fj.201802603RR
S6451	Salifungin Salifungin (Multifungin, Bromosalicylchloranilide) is an antifungal and may cause allergic contact dermatitis in some individuals.
S3722	Isavuconazole Isavuconazole (BAL-4815, RO-0094815) is a new extended-spectrum triazole with activity against yeasts, molds, and dimorphic fungi that inhibits cytochrome P450 (CYP)-dependent 14α-lanosterol demethylation, which is essential for fungal cell membrane ergosterol synthesis.
S5541	Dimetridazole Dimetridazole is an anti-fungal and anti-protozoal used for the control of infection in pigs, poultry, turkeys, game birds, pigeons and other caged birds.
S3979	Zinc Undecylenate Zinc Undecylenate (Zinc diundec-10-enoate, Zinc 10-undecenoate) is a natural or synthetic fungistatic fatty acid, antifungal Zinc Undecylenate is used topically in creams against fungal infections, eczemas, ringworm, and other cutaneous conditions.
S5086	p-Anisaldehyde p-Anisaldehyde (4-Methoxybenzaldehyde, Anisaldehyde, Anisic aldehyde, P-Methoxybenzaldehyde, 4-Anisaldehyde), an extract from Pimpinella anisum seeds, exhibits antifungal activity against a number of yeast and mold strains in laboratory media, fruit purees and fruit juices.
S6467	Fosfluconazole Fosfluconazole is a water-soluble phosphate prodrug of fluconazole, which is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.
S9444	Tomatine Tomatine (Lycopersicin) is a natural glycoalkaloid with fungicidal, antimicrobial, and insecticidal properties.
S4525	Ethylparaben Ethylparaben (Ethyl parahydroxybenzoate, Ethyl 4-hydroxybenzoate) is the ethyl ester of p-hydroxybenzoic acid, used as an antifungal preservative and food additive. It is a standardized chemical allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity.
S4878	Neticonazole Hydrochloride Neticonazole is an imidazole antifungal for the treatment of fungal skin infections.
S5845	Chalcone Chalcone (benzylideneacetophenone, phenyl styryl ketone, benzalacetophenone, β-phenylacrylophenone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones with antibacterial, antifungal, antitumor and anti-inflammatory properties.
S4793	Cedryl acetate Cedryl Acetate (Cedrol acetate, Cedranyl acetate), an acetylated from cedarwood oil, has been applied to chemistry for its properties as a chiral and cell signaling reagent with antifungal and immunotoxicity functions. Cedryl acetate exhibits α-glucosidase inhibitory activity.
S5512	Juglone Juglone (Regianin, 5-Hydroxy-1,4-naphthoquinone), a natural naphthoquinone found in the black walnut and other plants, has moderate antifungal activity and growth-stimulating effects to many types of plants. It sometimes can be used as an herbicide, as a dye for cloth and inks, and as a coloring agent for foods and cosmetics.	Nat Commun, 2019, 10(1):4013
S4516	(+)-Camphor Camphor is a waxy, flammable, white or transparent solid with a strong aroma, often used to relieve pain, reduce itching and treat fungal infections. It can activate TRPV1 and TRPV3.
S5373	Pseudolaric Acid B Pseudolaric Acid B, a natural diterpenoid compound isolated from the root and trunk bark of Pseudolaric kaempferi Gordon, has anti-fungal and anti-fertility properties.	Eur J Pharmacol, 2020, 876:173064
S4843	Potassium acetate Potassium acetate (Diuretic salt, Potassium ethanoate) is the potassium salt of acetic acid, which is a synthetic carboxylic acid with antibacterial and antifungal properties.
S4286	Anidulafungin (LY303366) Anidulafungin (LY303366), an echinocandin derivative, inhibits glucan synthase activity, used as an antifungal drug.	Pharmaceuticals (Basel), 2021, 14(4)338 Emerg Microbes Infect, 2020, 1-53 Antimicrob Agents Chemother, 2020, 64(2)	Effect of Anidulafungin on hemolysis. Arithmetic means ± SEM (n = 8) of the percentage of hemolytic erythrocytes following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Anidulafungin (1.5-6 μg/ml). ***(p<0.001) indicates significant difference from the absence of Anidulafungin (ANOVA).
S3910	4',7-Dimethoxyisoflavone 4',7-Dimethoxyisoflavone, isolated from the leaves of Albizzia lebbeck, shows antifungal activity in vitro.
S4287	Micafungin (FK 463) Sodium Micafungin Sodium (FK463, Mycamine) is an inhibitor of 1, 3-beta-D-glucan synthesis, used as an antifungal drug.	Bioorg Med Chem, 2021, 44:116293 Pharmaceuticals (Basel), 2021, 14(4)338 Antimicrob Agents Chemother, 2020, 64(2)	Effect of Micafungin on erythrocyte forward scatter. A. Original histogram of forward scatter of erythrocytes following exposure for 48 hours to Ringer solution without (grey area) and with (black line) presense of 25 µg/ml Micafungin. B. Arithmetic means ± SEM (n = 14) of the erythrocyte forward scatter (FSC) following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Micafungin (10-25 µg/ml). C. Arithmetic means ± SEM (n = 14) of the percentage of erythrocytes with forward scatter(FSC) <200 following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Micafungin (10-25 µg/ml). D. Arithmetic means ± SEM (n = 14) of the percentage of erythrocytes with forward scatter (FSC) >800 following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Micafungin (10-25 µg/ml). ***(p<0.001) indicates significant difference from the absence of Micafungin (ANOVA).
S4559	Cloxiquine Cloxiquine (5-Chloro-8-quinolinol, Dermofungin) is an antibacterial, antifungal, antiaging and antituberculosis drug.
S3985	Methyl 4-hydroxybenzoate Methyl 4-hydroxybenzoate (Methylparaben, Methyl p-hydroxybenzoate, Nipagin) is an anti-fungal agent often used in a variety of cosmetics, personal-care products and food preservatives.
S0491	Manogepix (E1210) Manogepix (E1210, MGX, APX001A) is a broad-spectrum and orally active antifungal agent that inhibits Gwt1/Gwt1p (GPI-anchored wall transfer protein 1), a protein that plays an important role in fungal cell wall integrity.
S3990	Trans-Anethole Trans-anethole (4-Propenylanisole) is a phenylpropene derivative found in many essential oils, including anise oil. It has neuromodulatory, anxiolytic, antioxidative, antifungal, anti-inflammatory, and immunomodulatory activities.

製品コード	製品説明	文献中Selleckの製品使用例	お客様のフィードバック
S1442	Voriconazole (UK-109496) Voriconazole (UK-109496) is a new triazole derivative similar to fluconazole and itraconazole that acts by inhibiting fungal cytochrome P-450-dependent, 14-alpha-sterol demethylase-mediated synthesis of ergosterol.	Front Microbiol, 2021, 12:649026 Antimicrob Agents Chemother, 2020, 6 pii: AAC Front Microbiol, 2020, 11:579362	Voriconazole increases the osteogenic activity of human osteoblasts in vitro. Osteoblasts were exposed to voriconazole (VCZ) or fluconazole (FCZ) at 15 or 200 μg/ml in osteoinductive medium (OS+) for up to 7 days. As a positive control, cells were also exposed to sodium fluoride (NaF) at 10 μM in nonosteoinductive medium (OS−). Osteoblastic differentiation was evaluated by measuring alkaline phosphatase (ALP) activity (A) and staining for calcium deposition with alazarin red S stain (B and C); calcium deposition was quantified by measuring the absorbance (A415) of extracted alazarin red S (B) and was assessed by the light microscopic appearance (white arrows) of stained osteoblast cultures (C). Values represent the means ± SD. *, P < 0.05, compared to osteoblasts grown under osteogenic conditions without treatment.
S5174	Kojic acid Kojic acid is a fungal metabolite that inhibits tyrosinase with an IC50 value of 30.6 µM for mushroom tyrosinase. It is a synthetic intermediate used for production of food additives.	Int J Mol Sci, 2017, 18(9)
S5083	Lentinan Lentinan (A823605, Bromoduline), isolated and purified from a hot water extract of Lentinula edodes fruit bodies, is a fungal polysaccharide immunomodulator with anti-tumor effects.

製品コード

製品説明

文献中Selleckの製品使用例

お客様のフィードバック

S1442

Voriconazole (UK-109496)

Voriconazole (UK-109496) is a new triazole derivative similar to fluconazole and itraconazole that acts by inhibiting fungal cytochrome P-450-dependent, 14-alpha-sterol demethylase-mediated synthesis of ergosterol.

Front Microbiol, 2021, 12:649026

Antimicrob Agents Chemother, 2020, 6 pii: AAC

Front Microbiol, 2020, 11:579362

S5174

Kojic acid

Kojic acid is a fungal metabolite that inhibits tyrosinase with an IC50 value of 30.6 µM for mushroom tyrosinase. It is a synthetic intermediate used for production of food additives.

Int J Mol Sci, 2017, 18(9)

S5083

Lentinan

Lentinan (A823605, Bromoduline), isolated and purified from a hot water extract of Lentinula edodes fruit bodies, is a fungal polysaccharide immunomodulator with anti-tumor effects.

研究分野別

製品類型

Fungal

阻害剤の選択性比較

Fungal製品