WH-4-023

For research use only. Not for use in humans.

製品コードS7565 別名:KIN001-112, KIN112

WH-4-023化学構造

分子量(MW):568.67

WH-4-023 is a potent and orally active Lck/Src inhibitor with IC50s of 2 nM and 6 nM in cell-free assays, respectively. Exhibits >300-fold selectivity against p38α and KDR. Also potently inhibits SIK (IC50 values are 10, 22 and 60 nM for SIK 1, 2 and 3 respectively) and displays selectivity over a range of closely related kinases.

サイズ 価格(税別) 在庫  
JPY 26400 あり
JPY 81100 あり
最寄りの販売代理店を探す

お探しのディーラーが見当たらない場合は直接こちらのメールアドレスまでお問い合わせください:[email protected]

バルク問合せ

カスタマーフィードバック(1)

  • (G-I) WB analysis of total LCK, LCK Y505, and Src Y416 expression in ALL-SIL, CCRF-CEM, and TALL-1. Cells were treated with DMSO only (Ctrl), dasatinib, bosutinib, nintedanib, or WH-4-023 overnight at the compound concentrations corresponding to the GI50 at 48 hr. Bos, bosutinib; Das, dasatinib; Nint, nintedanib; WH, WH-4-023.

    Blood, 2017, 130(25):2750-2761. WH-4-023 purchased from Selleck.

製品安全説明書

Src阻害剤の選択性比較

生物活性

製品説明 WH-4-023 is a potent and orally active Lck/Src inhibitor with IC50s of 2 nM and 6 nM in cell-free assays, respectively. Exhibits >300-fold selectivity against p38α and KDR. Also potently inhibits SIK (IC50 values are 10, 22 and 60 nM for SIK 1, 2 and 3 respectively) and displays selectivity over a range of closely related kinases.
ターゲット
Lck [1]
(Cell-free assay)
Src [1]
(Cell-free assay)
2 nM 6 nM
体外試験

WH-4-023 shows little activity on p38 and KDR. [1]

細胞データ
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
human EM-2 cell NIqzWJVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NULTRopsUW6qaXLpeIlwdiCxZjDoeY1idiCHTT2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{46OWVvMEig{txO MYfTRW5ITVJ?
human LAMA-84 cell MmW3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NV;pRZNrUW6qaXLpeIlwdiCxZjDoeY1idiCOQV3BMVg1KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oy55OHWtNFYh|ryP NUKyb3JiW0GQR1XS
human EoL-1-cell cell NVLwSGpGT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NELG[5JKdmirYnn0bY9vKG:oIHj1cYFvKEWxTD2xMYNmdGxiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD17LkWx[U0xPiEQvF2= NWXyU|NzW0GQR1XS
human MEG-01 cell MnTtS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2jHc2lvcGmkaYTpc44hd2ZiaIXtZY4hVUWJLUCxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU43O2VvMEWg{txO MkLXV2FPT0WU
human CTV-1 cell MYnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGryWFlKdmirYnn0bY9vKG:oIHj1cYFvKEOWVj2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{4yQGVvMEWg{txO NXv5WJIxW0GQR1XS
human BL-70 cell MW\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{\pdmlvcGmkaYTpc44hd2ZiaIXtZY4hSkxvN{CgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Mlcz\S1yNTFOwG0> MXfTRW5ITVJ?
human K-562 cell NUHaSmZjT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4jCdmlvcGmkaYTpc44hd2ZiaIXtZY4hUy13NkKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlAxODF4MjFOwG0> NGrTN|RUSU6JRWK=
human BV-173 cell M{\mNmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NE\z[|NKdmirYnn0bY9vKG:oIHj1cYFvKEKYLUG3N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvODByNUG0JO69VQ>? M4f3b3NCVkeHUh?=
human DOHH-2 cell M3PYb2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUXJcohq[mm2aX;uJI9nKGi3bXHuJGRQUEhvMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNFAxPTl5IN88US=> NFG2dnhUSU6JRWK=
human A704 cell NFfFdWdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVXEbGppUW6qaXLpeIlwdiCxZjDoeY1idiCDN{C0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xODF{NzFOwG0> M17kb3NCVkeHUh?=
human NCI-SNU-16 cell M3HEeWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYXnWXlOUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtV25WNTF4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6wNVU4OiEQvF2= Mn3LV2FPT0WU
human LC-2-ad cell MXPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUDoTFJvUW6qaXLpeIlwdiCxZjDoeY1idiCOQz2yMYFlKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yMkCzN{DPxE1? MYTTRW5ITVJ?
human LB2518-MEL cell MnWxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4PPTmlvcGmkaYTpc44hd2ZiaIXtZY4hVEJ{NUG4MW1GVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMES2Olch|ryP NIXOfnNUSU6JRWK=
human D-336MG cell MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MUjJcohq[mm2aX;uJI9nKGi3bXHuJGQuOzN4TVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlA1PjhzIN88US=> MmOwV2FPT0WU
human LB996-RCC cell NIDwZ3ZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NIrFdHRKdmirYnn0bY9vKG:oIHj1cYFvKEyEOUm2MXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMEW2Olgh|ryP M1rUNXNCVkeHUh?=
human Becker cell NGDJXZRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NU\weZl7UW6qaXLpeIlwdiCxZjDoeY1idiCEZXPr[ZIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjB4M{ixJO69VQ>? M1;k[nNCVkeHUh?=
human LB1047-RCC cell MmLFS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlPrTY5pcWKrdHnvckBw\iCqdX3hckBNSjFyNEetVmNEKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yN{W5NkDPxE1? M{[zSXNCVkeHUh?=
human KS-1 cell MXHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3G1V2lvcGmkaYTpc44hd2ZiaIXtZY4hU1NvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNFc4PThizszN M1LRZXNCVkeHUh?=
human MPP-89 cell MVfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2niOGlvcGmkaYTpc44hd2ZiaIXtZY4hVVCSLUi5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xQDJ{OTFOwG0> NYnaN3VmW0GQR1XS
human RXF393 cell M3L4SGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1PjPGlvcGmkaYTpc44hd2ZiaIXtZY4hWliIM{mzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4yODZ|MzFOwG0> MXfTRW5ITVJ?
LB831-BLC cell MXPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MX;Jcohq[mm2aX;uJI9nKGi3bXHuJGxDQDNzLVLMR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOTJ5MUWg{txO MVLTRW5ITVJ?
HUTU-80 cell MnL0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NE\hN5dKdmirYnn0bY9vKG:oIHj1cYFvKEiXVGWtPFAh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjF5NUK5JO69VQ>? Mn\4V2FPT0WU
A498 cell NYjoOYxKT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3jqOWlvcGmkaYTpc44hd2ZiaIXtZY4hSTR7ODDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNVg6PDVizszN NUTQ[GdFW0GQR1XS
MZ1-PC cell MnzNS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWPJcohq[mm2aX;uJI9nKGi3bXHuJG1bOS2SQzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNlI4OTZizszN MmOwV2FPT0WU
TE-8 cell MWPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXLJcohq[mm2aX;uJI9nKGi3bXHuJHRGNThiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkKzPVI1KM7:TR?= M4fHRnNCVkeHUh?=
MFH-ino cell  NIL6UlVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MV\Jcohq[mm2aX;uJI9nKGi3bXHuJG1HUC2rbn:gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlI{QTJ3IN88US=> MXjTRW5ITVJ?
TE-15 cell MlzmS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEnUOFdKdmirYnn0bY9vKG:oIHj1cYFvKFSHLUG1JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4zPDJ5NjFOwG0> M4TLTXNCVkeHUh?=
NTERA-S-cl-D1 cell NHTKPXRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M37sNmlvcGmkaYTpc44hd2ZiaIXtZY4hVlSHUlGtV{1kdC2GMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNlg5PTVizszN NH\6[4tUSU6JRWK=
COLO-829 cell NWT0dplsT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NF3PbGlKdmirYnn0bY9vKG:oIHj1cYFvKEORTF:tPFI6KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5|MUKxNkDPxE1? Mm\hV2FPT0WU
SW684 cell MU\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXrJcohq[mm2aX;uJI9nKGi3bXHuJHNYPjh2IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6zNlU5QCEQvF2= M4nydnNCVkeHUh?=
OS-RC-2 cell NX[4W203T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFH6[|RKdmirYnn0bY9vKG:oIHj1cYFvKE:VLWLDMVIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjN3MEGxJO69VQ>? MnLwV2FPT0WU
IST-MES1 cell MYLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{nJNGlvcGmkaYTpc44hd2ZiaIXtZY4hUVOWLV3FV|Eh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjN3N{KzJO69VQ>? M4DH[nNCVkeHUh?=
SNB75 cell MUPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mnj0TY5pcWKrdHnvckBw\iCqdX3hckBUVkJ5NTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuN|U4PzRizszN MmfYV2FPT0WU
SW954 cell MmT1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1P1T2lvcGmkaYTpc44hd2ZiaIXtZY4hW1d7NUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlM4OTZ|IN88US=> NIPpTmlUSU6JRWK=
RCC10RGB cell MmjRS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Ml:4TY5pcWKrdHnvckBw\iCqdX3hckBTS0NzMGLHRkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvPDJ4M{Gg{txO MV7TRW5ITVJ?
VA-ES-BJ cell NEWyZXVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWLJcohq[mm2aX;uJI9nKGi3bXHuJHZCNUWVLVLKJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE41PjJ4IN88US=> NVPNfHU6W0GQR1XS
NCI-H1648 cell MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{DObGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixOlQ5KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC53MUW4NkDPxE1? MoPxV2FPT0WU
PF-382 cell MX;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVfDXGlTUW6qaXLpeIlwdiCxZjDoeY1idiCSRj2zPFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjdyN{[zJO69VQ>? NILxN25USU6JRWK=
human Daudi cell MVjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MoOyTY5pcWKrdHnvckBw\iCqdX3hckBF[XWmaTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuO|E1OTFizszN MVjTRW5ITVJ?
SW982 cell NYXWXoI{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGPlTmxKdmirYnn0bY9vKG:oIHj1cYFvKFOZOUiyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE45PThzOTFOwG0> M1fQZXNCVkeHUh?=
SW872 cell M3Hmd2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVvJcohq[mm2aX;uJI9nKGi3bXHuJHNYQDd{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD64OlQ2QCEQvF2= MoD5V2FPT0WU
TE-12 cell NHHuRZBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVHJcohq[mm2aX;uJI9nKGi3bXHuJHRGNTF{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD64PFg{OSEQvF2= M4P4VnNCVkeHUh?=
human HOP-62 cell M1;ON2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4jGOWlvcGmkaYTpc44hd2ZiaIXtZY4hUE:SLU[yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE46OTV7OTFOwG0> NHX0XpRUSU6JRWK=
human NOS-1 cell NFzUd2dIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MX\Jcohq[mm2aX;uJI9nKGi3bXHuJG5QWy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD65OVA1PSEQvF2= Mn\HV2FPT0WU
human BL-41 cell NVyzXWVCT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2HZZWlvcGmkaYTpc44hd2ZiaIXtZY4hSkxvNEGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlAxODF|IN88US=> MYXTRW5ITVJ?
human TGBC24TKB cell Mo\4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NX7IR25KUW6qaXLpeIlwdiCxZjDoeY1idiCWR1LDNlRVU0JiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLkCzPFMyKM7:TR?= MnvKV2FPT0WU
human KGN cell NUnaSm9mT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVzJcohq[mm2aX;uJI9nKGi3bXHuJGtIViClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFwMEWyNUDPxE1? MkH2V2FPT0WU
human TK10 cell MkHMS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWPZTXRyUW6qaXLpeIlwdiCxZjDoeY1idiCWS{GwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4xQDRzODFOwG0> Mn;0V2FPT0WU
human GB-1 cell NGm2enlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnPaTY5pcWKrdHnvckBw\iCqdX3hckBISi1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT6xOlA3PCEQvF2= NUjIRm5OW0GQR1XS
human GCIY cell MmHlS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MkfJTY5pcWKrdHnvckBw\iCqdX3hckBIS0m\IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT6yN|AyKM7:TR?= MVHTRW5ITVJ?
human LXF-289 cell NXPGU|ZyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEj4PHJKdmirYnn0bY9vKG:oIHj1cYFvKEy[Rj2yPFkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjJ5MkW2JO69VQ>? Mnv0V2FPT0WU
RL95-2 cell MkT5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1vjb2lvcGmkaYTpc44hd2ZiaIXtZY4hWkx7NT2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4{OjR|NjFOwG0> NW\SZVBuW0GQR1XS
human SW962 cell NF63fnJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUH1TIJ7UW6qaXLpeIlwdiCxZjDoeY1idiCVV{m2NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvOzN5NEKg{txO M1nXUXNCVkeHUh?=
human HT-144 cell MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1:xN2lvcGmkaYTpc44hd2ZiaIXtZY4hUFRvMUS0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU41PDVzNzFOoI0> M{XVU3NCVkeHUh?=
human IST-SL2 cell MknRS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4f1eWlvcGmkaYTpc44hd2ZiaIXtZY4hUVOWLWPMNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvPDd2MkGg{txO Mmi5V2FPT0WU
human NB6 cell NUOwbppnT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVvJcohq[mm2aX;uJI9nKGi3bXHuJG5DPiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFwNkm2PVgh|ryP MVXTRW5ITVJ?
human SF126 cell NGHJNpFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYLJcohq[mm2aX;uJI9nKGi3bXHuJHNHOTJ4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT63N|E4QCEQvF2= MnvUV2FPT0WU
human BOKU cell MVTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmGyTY5pcWKrdHnvckBw\iCqdX3hckBDV0uXIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT64NFUzPyEQvF2= NUDoOXRuW0GQR1XS
human BB30-HNC cell MVrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2H3Z2lvcGmkaYTpc44hd2ZiaIXtZY4hSkJ|MD3IUmMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjh3NEeyJO69VQ>? NWDn[HdlW0GQR1XS
human KLE cell MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NELrOYJKdmirYnn0bY9vKG:oIHj1cYFvKEuORTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuPFYzOzJizszN MYXTRW5ITVJ?
human MLMA cell NHHY[oJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3SxbWlvcGmkaYTpc44hd2ZiaIXtZY4hVUyPQTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuPVI{OSEQvF2= MV;TRW5ITVJ?
human KINGS-1 cell NV;xb4x2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3HZPWlvcGmkaYTpc44hd2ZiaIXtZY4hU0mQR2OtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvQTZ6OUeg{txO MX\TRW5ITVJ?
human ES6 cell MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{LvZmlvcGmkaYTpc44hd2ZiaIXtZY4hTVN4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mj6wOVQxOSEQvF2= MYnTRW5ITVJ?
human SH-4 cell NG\vTmtIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NIj0NmlKdmirYnn0bY9vKG:oIHj1cYFvKFOKLUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlEzODV3IN88US=> Mn7xV2FPT0WU
human D-263MG cell MoK3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEGyZXZKdmirYnn0bY9vKG:oIHj1cYFvKERvMk[zUWch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjJ6OEWzJO69VQ>? M1vBOnNCVkeHUh?=
human SF268 cell MV7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWriTlBvUW6qaXLpeIlwdiCxZjDoeY1idiCVRkK2PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvPDh4OEKg{txO NUfnS5FEW0GQR1XS
human NB17 cell NULLXHNMT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFr3[plKdmirYnn0bY9vKG:oIHj1cYFvKE6EMUegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlYzQDd3IN88US=> Mn\5V2FPT0WU
human DMS-114 cell M1zae2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVjJcohq[mm2aX;uJI9nKGi3bXHuJGROWy1zMUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlc6ODJ{IN88US=> MmDGV2FPT0WU
MC116 cell M2DhWWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUX1NI1DUW6qaXLpeIlwdiCxZjDoeY1idiCPQ{GxOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvQDV5MESg{txO NGjtNolUSU6JRWK=
human NCI-H747 cell MUTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHTSTXdKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IO|Q4KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PS55NEG1PUDPxE1? NGr6eJJUSU6JRWK=
human A388 cell M3zZdmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Ml;QTY5pcWKrdHnvckBw\iCqdX3hckBCOzh6IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUSuOlc2QCEQvF2= M1\ZdnNCVkeHUh?=

他の多くの細胞株試験データをご覧になる場合はこちらをクリックして下さい

お薦めの試験操作(参考用のみ)

溶解度 (25°C)

体外 DMSO 12 mg/mL (21.1 mM) warming
Ethanol 6 mg/mL warmed (10.55 mM)
Water Insoluble
体内 左から(NMPから)右の順に溶剤を製品に加えます(文献ではなく、Selleckの実験によるデータ):
5% DMSO+30% PEG 300+5% Tween 80+ddH2O
混合させたのち直ちに使用することを推奨します。
1mg/mL

* 溶解度測定はSelleck技術部門によって行われており、その他文献に示されている溶解度と差異がある可能性がありますが、同一ロットの生産工程で起きる正常な現象ですからご安心ください。

化学情報

分子量 568.67
化学式

C32H36N6O4

CAS No. 837422-57-8
保管
in solvent
別名 KIN001-112, KIN112
Smiles COC1=CC=C(N(C(=O)OC2=C(C)C=CC=C2C)C3=CC=NC(=N3)NC4=CC=C(C=C4)N5CCN(C)CC5)C(=C1)OC

投与溶媒組成計算器(クリア溶液)

ステップ1:実験データを入力してください。(余分な消耗を考慮し動物一匹分の量を用意することをお勧めします。)
投与量 mg/kg 動物平均体重 g 投与体積(動物毎) ul 動物数
ステップ2:投与溶媒の組成を入力してください。(ロットごとに組成が異なるため、セレックから完全に溶解できる組成をお求めください。)
% DMSO % % Tween 80 % ddH2O
計算リセット

便利ツール

モル濃度計算器

モル濃度計算器

求めたい質量、体積または濃度を計算してください。

質量 (mg) = 濃度 (mM) x 体積 (mL) x 分子量 (g/mol)

モル濃度計算器方程式

  • 質量
    濃度
    体積
    分子量

*貯蔵液を準備するとき、常に、オンであるとわかる製品のバッチに特有の分子量を使って、を通してラベルとMSDS/COA(製品ページで利用可能な)。

希釈計算器

希釈計算器

貯蔵液を準備するために必要な希釈率を計算してください。Selleck希釈計算器は、以下の方程式に基づきます:

開始濃度 x 開始体積 = 最終濃度 x 最終体積

希釈の計算式

この方程式は、一般に略語を使われます:C1V1 = C2V2 ( 入力 出力 )

  • C1
    V1
    C2
    V2

常に貯蔵液を準備するとき、小びんラベルとMSDS/COA(オンラインで利用できる)で見つかる製品のバッチに特有の分子量を使ってください。

連続希釈計算器方程式

  • 連続希釈剤

  • 計算結果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量計算器

分子量计算器

そのモル質量と元素組成を計算するために、合成物の化学式を入力してください:

総分子量:g/mol

チップス: 化学式は大文字と小文字の区別ができます。C10H16N2O2 c10h16n2o2

モル濃度計算器

質量 濃度 体積 分子量

技術サポート

ストックの作り方、阻害剤の保管方法、細胞実験や動物実験の際に注意すべき点など、製品を取扱う時に問い合わせが多かった質問に対しては取扱説明書でお答えしています。

Handling Instructions

他に質問がある場合は、お気軽にお問い合わせください。

  • * 必須

Srcシグナル伝達経路

相関Src製品

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